Clinical trials: Point of Care Testing
Syphilis
Investigational Study to Evaluate the DPP® Syphilis Screen & Confirm Antibody Point-of-care Test (POCT) to Diagnose Infectious Syphilis
The goal of this observational study is to evaluate the sensitivity, specificity, and utility of the DPP® Syphilis Screen \& Confirm antibody point-of-care test (POCT) to diagnose infectious syphilis in participants attending the…
- Trial name
- NCT06927843
- Testing
- point of care test
- Where
- Canada
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Pulmonary Artery Hypertension
Assessing the Repeatability of NT-proBNP Testing Using Laboratory and Point of Care Testing in PAH
The purpose of this study is to examine N-terminal pro brain natriuretic peptide (NT-proBNP) and brain natriuretic peptide (BNP) biomarkers in a number of different settings including assessing the repeatability of laboratory and…
- Trial name
- REPEAT-PAH (NCT05421949)
- Testing
- Exercise group
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Preeclampsia
CercaTest™ Red Urine Test for Predicting Preeclampsia
The goal of this observational study is to predict preeclampsia in pregnant women aged 18 years or older with a singleton pregnancy at 20 or more weeks of gestation who present with suspected signs or symptoms of preeclampsia.
- Trial name
- PRE-CERCA (NCT07625501)
- Where
- Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- Chinese University of Hong Kong
Sexually Transmitted Infection, Chlamydia
Investigating Point-of-care Diagnostics for Sexually Transmitted Infections and Antimicrobial Resistance in Primary Care in Zimbabwe
A prospective interventional study to evaluate a strategy of point-of-care testing for sexually transmitted infections including chlamydia, gonorrhoea, trichomoniasis, syphilis, and Hepatitis B with comprehensive case management…
- Conditions
- Sexually Transmitted Infection, Chlamydia, Gonorrhea, Trichomoniasis
- Trial name
- IPSAZ (NCT05541081)
- Testing
- Point-of-care STI testing
- Where
- Zimbabwe
- Volunteers
- 1,005 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Hepatitis C, Chronic
HCV RNA Fingerstick Assay as Useful Point of Care of Diagnostic Tool for Drug Users in Brussels
The main objective of this study is to assess the interest (linkage to care) of the Cepheid GeneXpert HCV VL Fingerstick test in Brussels among drug users or former users in contact with the Réseau Hépatite C Bruxelles…
- Trial name
- NCT04610762
- Testing
- GeneXpert HCV VL Fingerstick test
- Where
- Belgium
- Volunteers
- 103 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Syphilis
The Feasibility of Implementing Syphilis Point-of-care Testing Into a Prenatal Clinic for People Facing Barriers to Care
The goal of this clinical trial is to learn if a finger-prick blood test for rapid diagnosis of syphilis infection can be implemented in a low-barrier prenatal clinic for people at risk of syphilis in pregnancy.
- Trial name
- PRESSING (NCT06829602)
- Testing
- Rapid Syphilis/HIV point-of-care test
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- McMaster University
Platelet Aggregation, Spontaneous, Atherosclerosis
Effects of Fish Oil on Platelet Function and Coagulation
Many patients undergoing surgery use naturopathic drugs, including fish oil. Fish oil has been reported to increase bleeding in patients through inhibiting platelet aggregation and prolonging of clot formation time.
- Conditions
- Platelet Aggregation, Spontaneous, Atherosclerosis, Surgery
- Trial name
- FOILP (NCT03048981)
- Testing
- Fish oil
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Region Skane
C.Surgical Procedure; Cardiac, Blood Transfusion
Cost-Utility Analysis of Management of Peri Operative Haemorrhage Following Cardiac Surgery With Cardiopulmonary Bypass
Peri operative haemorrhage following cardio Pulmonary Bypass may occur in 5 to 10% of cardiac surgical interventions. Treatment of such complication often necessitates various combinations therapeutic intervention including…
- Conditions
- C.Surgical Procedure; Cardiac, Blood Transfusion, Blood Coagulation Disorders, Bypass, Cardiopulmonary
- Trial name
- IMOTEC (NCT02972684)
- Testing
- Thrombo-elastometry POC testing
- Where
- 15 sites in France
- Volunteers
- 1,098 people
- Sponsor
- Nantes University Hospital
Cervical Cancer
Comparison of Cervical Cancer Screening Tests in HIV-infected Women in Lusaka, Zambia
This study will compare the test performance characteristics of visual inspection with acetic acid (VIA), Xpert HPV, and OncoE6 in HIV-infected women, to inform the possible inclusion of these molecular tests in future cervical…
- Trial name
- NCT02688816
- Testing
- Xpert HPV, OncoE6
- Where
- Zambia
- Volunteers
- 200 people
- Sponsor
- Carla Chibwesha, MD
Multiplex Testing of HIV, HBV, HCV and Syphilis, HIV
Clinical Performance Evaluation of MagIA IVD-MD Multiplex Testing (HIV/HBV/HCV/Syphilis)
Performance study to evaluate the clinical performance of the In-Vitro Diagnostics Medical Device MagIA H3S (a Multiplex Point-of-Care test for the combined detection of Human Immunodeficiency Virus (HIV), Hepatitis B and C and…
- Conditions
- Multiplex Testing of HIV, HBV, HCV and Syphilis, HIV, HBV, HCV
- Trial name
- MAGICS IBCS (NCT07170748)
- Where
- 2 sites in Côte d’Ivoire, Kenya
- Volunteers
- 2,950 people, healthy volunteers welcome
- Sponsor
- MagIA Diagnostics
Urinary Tract Infection (Diagnosis)
Rapid Point-of-care Bacteriuria and Microbial Susceptibility for Women With Suspected Uncomplicated Urinary Tract Infections: Diagnostic Accuracy in General Practice.
In this study, adult women presenting at their general practitioner with a likely bladder infection (with symptoms like a burning sensation when urinating, pain in the lower abdomen, and frequent or urgent need to urinate) will…
- Trial name
- NCT06625268
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Wuerzburg University Hospital
HIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV)
Combating Related Epidemics in HCV
This is a two-arm cluster randomized control trial to evaluate the effectiveness of a single-visit point-of-care (POC) test and treat bundle (intervention arm) compared to the current standard-of-care (SOC, control arm).
- Conditions
- HIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV), HEPATITIS C (HCV)
- Trial name
- CREST (NCT07560046)
- Testing
- Cepheid GeneXpert HCV Test, Abbott Determine HIV - 1/2 Ag/Ab, Abbott Determine HbsAg 2
- Volunteers
- 1,280 people
- Sponsor
- Duke University
Sepsis
Analytical Validation of the abioSCOPE Device With a PSP Test: Point-of-Care Precision, Sample Type Comparison and Sample Stability
Abionic SA has developed a novel point-of-care (POC) platform, the abioSCOPE, and an in vitro diagnostic kit for the quantification of the pancreatic stone protein (PSP) to be analyzed specifically with the abioSCOPE® device.
- Trial name
- AB-PSP-005 (NCT04797117)
- Testing
- blood sample
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Limoges
Early Infant HIV Diagnosis
Point of Care Virologic Testing to Improve Outcomes of HIV-Infected Children
This is a two-arm, unmasked, randomized, controlled trial to test the effectiveness of the Alere Q point-of-care (POC) HIV diagnostic assay for use in resource-poor settings.
- Trial name
- NCT02682810
- Testing
- DNA PCR HIV diagnostic test, Alere Q
- Where
- 6 sites in Zambia
- Volunteers
- 4,000 people
- Sponsor
- University of North Carolina, Chapel Hill
Infectious Diseases, Emerging
Development of a Rapid Diagnostic Test to Identify Crimean-Congo Hemorrhagic Fever - Research and Development Testing
Background Crimean-Congo Haemorrhagic Fever (CCHF) is a rare disease with a death rate between 10% and 50%, rising to 80% during outbreaks.
- Trial name
- DETECT-R&D (NCT06894758)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Celiac Disease
ICT Tools for the Diagnosis of Autoimmune Diseases
The ITAMA project, which ended in 03/2022, came from the need to increase/anticipate the number of diagnosed cases of celiac disease (CD).
- Trial name
- ITAMA_CAP (NCT05715970)
- Testing
- PoCT+questionnaire administration
- Where
- 2 sites in Italy, Malta
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Anticoagulation With NOAC
Specific PoC Testing of Coagulation in Patients Treated With DOAC 1
The investigators study aims to test the correlation between the Cascade Abrazo point-of-care testing (POCT) device (Helena Laboratories, USA) and plasma levels of apixaban, dabigatran, edoxaban and rivaroxaban, and to determine…
- Trial name
- SPOCT-DOAC 1 (NCT02825394)
- Testing
- anti-Xa activity point-of-care testing (aXa-POCT), ecarin clotting time point-of-care testing (ECT-POCT)
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- University Hospital Tuebingen
Neonatal Disorder
Gastric Lipase Enhanced Nasogastric Tube Study in Neonates
The newborn infants who are sick and those who are born prior to due date (preterm) are admitted to the neonatal unit. These babies are unable to feed through their mouth, so a special tube is passed through their nose to the…
- Trial name
- NCT04271995
- Where
- United Kingdom
- Volunteers
- 233 people
- Sponsor
- Imperial College London
Severe Sepsis With Septic Shock, Lactate Blood Increase
Saving Lives by Early Detection and Treatment of Sepsis and Septic Shock by Point of Care Lactate Test in Adults
Burden: The global burden of sepsis is difficult to ascertain, although a recent scientific publication estimated that in 2017 there were 48.9 million cases and 11 million sepsis-related deaths worldwide, which accounted for…
- Trial name
- POCLactate (NCT05108467)
- Testing
- Point of care Lactate
- Where
- Bangladesh
- Volunteers
- 80 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Hepatitis C
Rapid Point-of-care Testing for Hepatitis C in Community Clinics (RAPID-EC) Pilot Study
The Rapid-EC pilot study will determine feasibility of providing rapid point-of-care (POC) testing for HCV in community clinics, and whether the availability of POC testing increases uptake of testing, engagement in care and…
- Trial name
- NCT03231930
- Testing
- OraQuick HCV Ab test, Xpert HCV viral load test
- Where
- 3 sites in Australia
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Macfarlane Burnet Institute for Medical Research and Public Health Ltd