Clinical trials: Point-of-Care Systems
Abdominal Pain, Thoracic Pain
PoCUS Impact on the Diagnostic Approach for Thoracic and Abdominal Pain in the ED
Many medical specialties and paramedical fields are increasingly using point-of-care ultrasound (PoCUS). In daily practice, thoracic and abdominal pain constitute a significant portion of emergency department consultations.
- Trial name
- DATAPUS (NCT06827730)
- Testing
- Point of care ultrasound
- Where
- Belgium
- Volunteers
- 406 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Free Air in Abdomen
Point of Care Ultrasound for Diagnosis of Abdominal Free Air
This study evaluates the ability of ultrasound to identify intraperitoneal free air. The study will consist of blinded review of abdominal ultrasound images of patients before and after laparoscopic surgery, a procedure which…
- Trial name
- NCT03719872
- Testing
- Pre-Operative Transabdominal Ultrasound, Post-Operative Transabdominal Ultrasound
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- David Blehar
Emergencies, Care
Impact of Biological Point of Care Devices Implementation on the Length of Stay of Patients in Emergency Room
"Main objective: to demonstrate that the implementation of an extended panel solution for the point of care analysis of biological parameters (point of care : POC) in an emergency department (ED) reduces the length of stay (LOS)…
- Trial name
- SUPOC (NCT03840564)
- Testing
- Point of care (POC)
- Where
- France
- Volunteers
- 20,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Renal Colic
"Point of Care" Ultrasound and Renal Colic
The management of renal colic in emergency departments follows the recommendations established at the 8th consensus conference of 2008 on the management of renal colic in emergency services.
- Trial name
- ECHOLINE (NCT04169555)
- Testing
- Ultrasound, Standard care
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Lille Catholic University
Emergency, Point of Care Ultrasound (POCUS)
Italian Data Registry of Patients Undergoing Peripheral Nerve Block Performed in the Emergency Departments
This data registry aim is to describe the practice of Point-of-Care Ultrasound Guided Regional Anaesthesia (POCUS-GRA) in emergency departments of nosocomial hospitals where, the organizational structure, has already provided for…
- Conditions
- Emergency, Point of Care Ultrasound (POCUS), Anesthesia, Acute Pain
- Trial name
- ED-RA (NCT06707558)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Bone Fractures
Ultrasound Assessment of Pediatric Fracture Healing With the PLUS Score
This observational study investigates whether ultrasound can safely and accurately monitor the healing of bone fractures in children, comparing it to standard X-rays.
- Trial name
- USG-FRACTHEAL (NCT07755787)
- Testing
- Point-of-care ultrasound
- Where
- Czechia
- Volunteers
- 1,200 people
- Sponsor
- University Hospital Hradec Kralove
Combined Point of Care Diagnostic of HIV, HBV and HCV
Prospective Clinical Performance Evaluation of the In-Vitro Diagnostics Medical Device MaGIA IBC for the CombIned screENing of HIV, Hepatitis B and Hepatitis C
Prospective, cross-sectional, adaptative study to evaluate the clinical performance of the In-Vitro Diagnostics Medical Device MagIA IBC (a Multiplex Point-of-Care Test for the detection of HIV, HBV and HCV) in detecting anti-HIV…
- Trial name
- MAGICIEN (NCT06082336)
- Testing
- MagIA IBC test in capillary blood, MagIA IBC test in other blood matrices
- Where
- 2 sites in France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- MagIA Diagnostics
Heart Failure
Comparing Diuretic Strategies in Hospitalized Heart Failure
We will conduct a pragmatic randomized trial comparing whether using a combination of two types of diuretics (loop + thiazide) compared with using a single diuretic (loop only) will result in shorter hospital stays for patients…
- Trial name
- NCT03999216
- Testing
- Loop Diuretics vs. loop + thiazide diuretics
- Where
- United States
- Sponsor
- Stanford University
Oral Potentially Malignant Lesions, Oral Potentially Malignant Disorders
Feasibility and Validation of an Automated AI-Enabled Deep Ultraviolet (DUV) Cytology Platform for Point-of-Care Oral Cancer Triage
This research study evaluates an experimental, point-of-care tool that combines Deep Ultraviolet (DUV) light imaging with Artificial Intelligence (AI) to rapidly screen for oral cancer and pre-cancer (dysplasia).
- Conditions
- Oral Potentially Malignant Lesions, Oral Potentially Malignant Disorders, Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Oral Cancer
- Trial name
- DEEP UV-M (NCT07842211)
- Testing
- Deep UV-M and AI Cytology Triage
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Anh Le
Hepatitis C, RDT
Simplifying Hepatitis C Pathways for People Who Inject Drugs in Armenia, Georgia, and Tanzania
The goal of this non-randomised, quasi-experimental, prospective comparative trial is to trial simplified care pathways for hepatitis C testing and treatment for people who inject drugs in Armenia, Georgia, and Tanzania.
- Trial name
- CUTTS HepC (NCT06159504)
- Testing
- sofosbuvir/velpatasvir (SOF/VEL), Shortened read time of rapid diagnostic test for hepatitis C virus.
- Where
- Armenia
- Volunteers
- 3,040 people
- Sponsor
- Médecins du Monde
Sickle Cell Disease
Sickle Cell Disease, Hemechip
Sickle cell disease is very common in Nigeria. Early diagnosis is important to prevent or reduce serious complications from the disease and to enable children stay healthy.
- Trial name
- NCT03948516
- Where
- 7 sites in United States, Nigeria
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Small Bowel Obstruction, Point of Care Ultrasound
POCUS for Small Bowel Obstruction in the ED: a Retrospective Study
This study protocol aims to evaluate the impact of point-of-care ultrasound (POCUS) on the diagnosis and management of small bowel obstruction (SBO) in the emergency department (ED).
- Trial name
- SBOCUS (NCT05864378)
- Volunteers
- 230 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Platelet Function Tests, Thrombin Generation Tests
Point-of-care Assessment of Thrombin Generation and Platelet Function in Children Requiring Cardiopulmonary Bypass
Coagulopathy after cardiopulmonary bypass (CPB) is associated with increased morbidity and mortality. Clot formation and clot stability are important factors in coagulation and hemostasis.
- Conditions
- Platelet Function Tests, Thrombin Generation Tests, Perioperative Coagulopathy
- Trial name
- NCT02833025
- Testing
- Thrombin generation and Platelet Function Testing
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- The Hospital for Sick Children
Diabetes Mellitus
Tailored Antiplatelet Therapy During Percutaneous Coronary Intervention in Patients With Diabetes Mellitus
The researchers aimed to investigate the effect of point-of-care platelet function assay on the periprocedural cardiac enzyme elevation in patients with diabetes mellitus.
- Trial name
- NCT01475552
- Testing
- Abciximab, control
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Seoul National University Bundang Hospital
Septic Shock, Sepsis
Impact of Systematic Point-of-Care Ultrasound Implementation on Clinical Outcomes and Survival in Septic Shock: A Retrospective Single-Center Cohort Study
This study aims to evaluate the clinical impact of the systematic implementation of point-of-care ultrasound (POCUS) in the management of patients with septic shock in the intensive care unit (ICU).
- Trial name
- SHOCK (NCT07565649)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Acute Coronary Syndrome, Chest Pain
PARA-HEART Pilot Implementation
Approximately 8-10 million patients complaining of chest pain present to an Emergency Department (ED) annually in the United States.
- Trial name
- PARA-HEART (NCT02709135)
- Where
- United States
- Volunteers
- 511 people
- Sponsor
- Wake Forest University Health Sciences
Prosthetic Joint Infection
Diagnostic Utility of a Novel Point-of-Care Test of Calprotectin for Revision Total Knee Arthroplasty
The purpose of this study is to investigate whether there are quantifiable differences in the level of calprotectin in the synovial fluid that allow separation of different modes of joint implant failure (e.g.
- Trial name
- NCT03694925
- Testing
- Calprotectin test
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- The Cleveland Clinic
Gastric Emptying, Gastroparesis
Gastric Emptying Recovery After GLP-1 RA Cessation
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can delay gastric emptying and may increase residual gastric contents before general anesthesia.
- Conditions
- Gastric Emptying, Gastroparesis, Preoperative Care
- Trial name
- NCT07360262
- Testing
- Preoperative gastric ultrasound
- Where
- 2 sites in South Korea
- Volunteers
- 186 people
- Sponsor
- Wonkwang University Hospital
Blood Loss Massive, Post Operative Hemorrhage
Evaluation of the Quantra QStat System in Obstetric Patients
This pilot study will assess the performance of the Quantra System with the QStat Cartridge versus standard of care coagulation testing in bleeding pregnant women at delivery.
- Trial name
- NCT05875987
- Testing
- Quantra System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- HemoSonics LLC
Enteral and Supplement Feeds Adverse Reaction, Gastrointestinal Diseases
Using Magnetic Field Tracking to Confirm Nasogastric Tube Placement at Point of Care
This is a trial on the feasibility of magnetic tracking for the confirmation of nasogastric tube location in human patients.
- Conditions
- Enteral and Supplement Feeds Adverse Reaction, Gastrointestinal Diseases, Esophagus Disorder
- Trial name
- NCT05204901
- Testing
- Insertion and withdrawal of a magnetic-tipped wire into the lumen of the nasogastric tube for tracking of its position
- Where
- Singapore
- Volunteers
- 10 people
- Sponsor
- Tan Tock Seng Hospital
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