Clinical trials: Point-of-Care Systems
Paracetamol Overdose
The Markers and Paracetamol Poisoning Study 2
Paracetamol overdose is one of the most common medical emergencies. Annually in the UK, 100,000 people seek medical attention and 50,000 need hospital admission.
- Trial name
- MAPP2 (NCT03497104)
- Testing
- Surplus blood tests
- Where
- United Kingdom
- Volunteers
- 464 people
- Sponsor
- NHS Lothian
Pneumonia, Childhood Pneumonia
Diagnostic Accuracy of Lung Ultrasound for Pneumonia Diagnosis in Children
Chest X-ray is historically being used as an imaging standard to aid to the diagnosis of childhood pneumonia, however, the evidence does not support it as a perfect imaging tool.
- Trial name
- LUS (NCT07331311)
- Testing
- LUS as a chest imaging tool
- Where
- Nepal
- Volunteers
- 320 people
- Sponsor
- Nagasaki University
Pregnancy Testing
Efficacy Evaluation of Using Finger Stick Peripheral Blood for Point of Care Pregnancy Testing
To evaluate the efficacy of using peripheral blood for POC pregnancy testing in known pregnant participants.
- Trial name
- POCPREG (NCT06747598)
- Testing
- pregnancy test
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Nebraska
End Stage Renal Disease
Reducing Arrhythmia in Dialysis by Adjusting the Rx Electrolytes/Ultrafiltration, Study A
The primary purpose of this study is to test the feasibility of trials which change the dialysate (dialysis bath prescription) of potassium and bicarbonate according to a standardized algorithm and according to the results of…
- Trial name
- RADAR-A (NCT03519347)
- Testing
- Potassium Removal Maximization, Potassium Gradient Minimization, Alkalosis Avoidance
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- NYU Langone Health
Coronary Artery Disease
Pre-hOspital Evaluation of Chest Pain Patients With sUspected Non ST-segment eLevation myocARdial Infarction Using the HEART-score With a Troponin Point-of-care Test
Overcrowding in the emergency department is an increasing problem in hospitals worldwide. Point-of-care Troponin (POC cTn) testing combined with a well investigated risk stratification tool (HEART-score) used in the ambulance may…
- Trial name
- POPular HEART (NCT04851418)
- Testing
- Possible NSTE-ACS
- Where
- 2 sites in Netherlands
- Volunteers
- 650 people
- Sponsor
- St. Antonius Hospital
Community-acquired Pneumonia
Impact of Comprehensive Molecular Tests on Antimicrobial Stewardship in Community-acquired Pneumonia
Background: Community-acquired pneumonia (CAP) continues to be a major health problem with significant mortality and it's one of the main causes of antibiotic prescription.
- Trial name
- RADICAP (NCT04158492)
- Testing
- real-time multiplex PCR, Standard diagnostic procedures
- Where
- 4 sites in Spain
- Volunteers
- 242 people
- Sponsor
- Hospital Universitari de Bellvitge
Gastric Feeding Tubes, Ultrasound
Gastric Ultrasound Feeding Tube Placement Confirmation Study
Objective This study aims to assess the accuracy and reliability of ultrasound in determining the correct placement of gastric feeding tubes (GFTs) in intensive care patients.
- Trial name
- GUT (NCT06595537)
- Testing
- Hand held ultrasound
- Where
- Netherlands
- Volunteers
- 58 people
- Sponsor
- Leiden University Medical Center
Covid19
Point of Care Evaluation of Novir 2019-nCoV Immunoglobulin G/ Immunoglobulin M (IgG/IgM) Antibody Test (Collodial Gold)
This clinical study is designed to test the efficacy of the Novir 2019-nCoV Immunoglobulin M/Immunoglobulin G Antibody Test in a point-of-care setting to support the increasing need for rapid screening in the detection of…
- Trial name
- NOVIR POC (NCT04902911)
- Testing
- COVID-19 SARS-CoV IgG/IgM antibody rapid test
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Heart Failure, Congestive, Cardiac Failure
Pocket-sized Ultrasound for Point-of-care Diagnosis of Heart Failure
Assessment of pocket sized ultrasound (Vscan GE Healthcare) for diagnosing heart failure in primary care patients, with a comprehensive cardiac ultrasound examination (Siemens Acusan P10) performed at a specialized the eco.lab…
- Trial name
- POCUS (NCT02939157)
- Testing
- Cardiac diagnostic ultrasound
- Volunteers
- 158 people
- Sponsor
- Umeå University
Syncope
Point-of-Care Ultrasound in the Emergency Department Evaluation of Syncope
The purpose of this study is to determine whether point-of-care (bedside) ultrasound assists physicians in the evaluation and management of patients with syncope.
- Trial name
- NCT01671371
- Testing
- Point-of-Care Ultrasound
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Yale University
Small Bowel Obstruction
Point of Care Ultrasound for Suspected Small Bowel Obstruction in the Emergency Department
The primary purpose of this study is to determine the accuracy of ultrasound in diagnosing small bowel obstruction in emergency department patients, as compared to the criterion standards of computed tomography, operative…
- Trial name
- NCT02190981
- Testing
- Ultrasound for Small Bowel Obstruction
- Where
- 3 sites in United States
- Volunteers
- 217 people
- Sponsor
- WellSpan Health
Preeclampsia
CercaTest™ Red Urine Test for Predicting Preeclampsia
The goal of this observational study is to predict preeclampsia in pregnant women aged 18 years or older with a singleton pregnancy at 20 or more weeks of gestation who present with suspected signs or symptoms of preeclampsia.
- Trial name
- PRE-CERCA (NCT07625501)
- Where
- Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- Chinese University of Hong Kong
Hip Orthopaedic
Cohort Study of Perioperative Ultrasound and Delirium Following Hip Surgery
About this study This is a single-center prospective observational cohort study involving older adults undergoing hip surgery. The investigators will collect clinical and ultrasound-related information without changing routine…
- Trial name
- UPED (NCT07820007)
- Testing
- Peri-operative observational data collection of bedside ultrasound and hemodynamic parameters
- Where
- China
- Volunteers
- 620 people
- Sponsor
- Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine
Intra-operative Hypotension
Preoperative Point of Care Ultrasound Guided Fluid Optimization and Intravenous Ondansetron to Prevent General Anesthesia-Induced Hypotension
Hypotension is a common side-effect of general anesthesia induction and is related to adverse outcomes including significantly increasing risk of one-year mortality.
- Trial name
- NCT05784350
- Testing
- fluid boluses guided by IVC diameter via US/administration of pre-operative IV Odansetrone
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Meir Medical Center
Deep Vein Thrombosis
Systematic Machine Learning Algorithm for Rapid Thrombosis Detection
The goal of this clinical trial is to compare the use of a machine learning-based algorithm and point-of-care D-dimer to laboratory D-dimer and compression ultrasound to exclude deep vein thrombosis in the under extremities in…
- Trial name
- DVT-SMART (NCT06842446)
- Testing
- POC D-dimer, POC ultrasound, Machine learning model
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Ostfold Hospital Trust
Preeclampsia, Pulmonary Edema
Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia
The study is planned to describe the prevalence and severity of cardiac, lung and optic-nerve sheath diameter (ONSD) ultrasound abnormalities in women with early onset preeclampsia with severe features.
- Conditions
- Preeclampsia, Pulmonary Edema, Cardiac Function
- Trial name
- NCT05662995
- Testing
- Lung ultrasound
- Where
- South Africa
- Volunteers
- 60 people
- Sponsor
- University of Cape Town
Anticoagulation
Point-of-Care Testing (POCT) for Guided Precision Anticoagulation With Warfarin: A Multicenter, Non-concurrent Controlled Study
This study aims to compare the key clinical indicators such as the time to achieve INR target, frequency of dose adjustment, and the incidence of thrombotic and hemorrhagic events between Point-of-Care Testing (POCT) and…
- Trial name
- NCT06645275
- Testing
- POCT test
- Volunteers
- 416 people
- Sponsor
- RenJi Hospital
Tuberculosis
Predicting the Future: Incipient Tuberculosis
The investigators will study, prospectively, if contacts (household or close contacts) of tuberculosis (TB) patients with high C-reactive protein (CRP), low hemoglobin (Hb) levels, and a positive Xpert Host Response (HR)…
- Trial name
- PreFIT (NCT04825327)
- Where
- 3 sites in Mozambique, South Africa and 1 more
- Volunteers
- 3,016 people
- Sponsor
- Amsterdam Institute for Global Health and Development
Emergency Medical Services, Nursing Care
High-Sensitivity Troponin I in Addition to Guideline-Based Care in EMS
The TIGER study is a study investigating the utlility of a point-of-care blood analyse of Troponin I to help identify patients with heart attacks in the prehospital emergency care.
- Conditions
- Emergency Medical Services, Nursing Care, Cardiology, Myocardial Infarction
- Trial name
- TIGER (NCT07008391)
- Testing
- high sensitivity Troponin I
- Where
- Sweden
- Volunteers
- 1,419 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Influenza, Influenza-like Illness
Abbott ID NOW Point-of-Care Testing
With the rapid aging of the global population, long-term care facilities (LTCFs) have become an increasingly important component of modern public health systems.
- Trial name
- IDNOW2026 (NCT07846423)
- Testing
- Abbott ID NOW Point-of-Care Testing, Standard Laboratory-Based RT-PCR Diagnostic Pathway
- Where
- Taiwan
- Volunteers
- 1,080 people
- Sponsor
- China Medical University Hospital
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