Clinical trials: Point-of-Care Systems
Blood Coagulation Disorders, Blood Coagulation Disorder With Prolonged Bleeding Time
Accuracy of a Portable International Normalized Ratio Monitor in Elderly Patients
Oral anticoagulants vitamin K antagonists (VKA) have been used for many years in the treatment of thromboembolic disorders, which are among the most costly diseases in terms of public health resources.
- Conditions
- Blood Coagulation Disorders, Blood Coagulation Disorder With Prolonged Bleeding Time, Blood Coagulation Disorder With Prolonged Coagulation Time
- Trial name
- AGINR (NCT01930916)
- Testing
- INR capillary measurement with INRatio 2 device, antiphospholipid antibodies and lupus anticoagulant
- Where
- 4 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
Dehydration, Seizure
Point of Care Device Use in the Pediatric Emergency Department
To compare the effect of "point-of-care" (POC) analysis of blood work with traditional laboratory methods on length of stay in a pediatric emergency department (PED).
- Conditions
- Dehydration, Seizure, Gastroenteritis, Hyperglycemia
- Trial name
- NCT00285285
- Testing
- Point of Care Device; i-Stat Analyzer
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yale University
Tuberculosis
Xpert Active Case-finding Trial 3 (XACT-3)
TB remains the foremost infectious disease killer globally. A startling statistic is that two out of every five TB cases globally (40%) remain undiagnosed and untreated.
- Trial name
- XACT-3 (NCT04303104)
- Testing
- GeneXpert Edge, GeneXpert Ultra
- Where
- 4 sites in Mozambique, South Africa and 2 more
- Volunteers
- 3,523 people
- Sponsor
- University of Cape Town
SARS-CoV2 Infection
Novel SARS-CoV-2 Point-of-care Testing
The aim of the project is to study the feasibility of implementing a novel point-of-care test (POCT) for rapid detection of SARS-CoV-2 infection.
- Trial name
- NCT05034978
- Testing
- no intervention
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Intensive Care Unit
Regional Anaesthesia in Intensive Care Unit
Pain is a major problem in Intensive Care Unit (ICU). Adequate pain management not only means decreasing the pain intensity, but also improving the functionality and allowing the early mobilization that is a prerequisite for…
- Trial name
- Week'ALR (NCT05131633)
- Where
- 19 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chest Pain
The Effects of Point-of-care Ultrasonography
Background: When used with standard diagnostic testing, point-of-care ultrasonography (POCUS) might improve the proportion of patients admitted with chest pain (CP) who are correctly diagnosed, decrease length of stay (LOS) in…
- Trial name
- NCT04429698
- Testing
- Point of care ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people
- Sponsor
- Sakarya University
Inflammatory Bowel Diseases, Crohn Disease
Intestinal Ultrasound Guided Management in Inflammatory Bowel Disease
This randomized controlled trial evaluates whether adding point-of-care intestinal ultrasound (IUS) to standard of care changes clinical management in patients with inflammatory bowel disease (IBD).
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Colitis, Ulcerative
- Trial name
- NCT07775352
- Testing
- Intestinal ultrasound (IUS), Standard of care
- Where
- Thailand
- Volunteers
- 137 people
- Sponsor
- Mahidol University
Acute Coronary Syndrome, Myocardial Infarction
RAMP 200 / RAMP Cardiovascular Tests at the Point-of-Care
This clinical investigation is designed to demonstrate the performance characteristics of the RAMP® cardiac tests analyzed on the RAMP® 200 by non-laboratorial Operators at the point-of-care when compared to the results for the…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Heart Failure, Congestive Heart Failure
- Trial name
- C-POC (NCT02191735)
- Testing
- RAMP 200, RAMP Reader
- Where
- 3 sites in United States
- Volunteers
- 719 people
- Sponsor
- Response Biomedical Corp.
Airway Assessment
Upper Airway Ultrasound in the Assessment of Difficult Visualization of the Larynx
failed and Difficult tracheal intubation after direct laryngoscopy is a dreaded complication of general anesthesia as it is associated with serious morbidity and mortality.
- Trial name
- NCT04273074
- Testing
- sonographic assessment
- Where
- Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Cairo University
Schizophrenia
Hematological Clozapine Monitoring With a Point-of-care Device (CHEMPAQ)
Clozapine remain the drug of choice for treatment resistant schizophrenia and up to 60% of patients not responding to other antipsychotics will respond to clozapine.
- Trial name
- CHEMPAQ (NCT01138618)
- Testing
- Venous blod sample, CHEMPAQ
- Where
- 6 sites in Denmark
- Volunteers
- 85 people
- Sponsor
- University of Aarhus
Asthma Management, Asthma
eAMS-Eco: Implementation of a Tool for Climate Conscious Inhaler Prescribing
The goal of this study is to determine whether an 'eco' version of the Electronic Asthma Management System (eAMS) can reduce inhaler carbon emissions in primary care, in patients with asthma.
- Conditions
- Asthma Management, Asthma, Computerized Decision Support System, Primary Care
- Trial name
- NCT07638735
- Testing
- Climate-Conscious Clinical Decision Support System for Asthma Management
- Where
- 2 sites in Canada
- Volunteers
- 95 people
- Sponsor
- University of Toronto
COVID-19, Asymptomatic COVID-19
A Clinical Evaluation of Proof Diagnostics Test System Including the Proof Diagnostics Reader and COVID-19 Test
To determine the accuracy of Proof Diagnostics COVID-19 Test in the intended, symptomatic and suspected/at-risk asymptomatic population and point-of-care use as compared to a standard molecular comparator, Quidel Lyra SARS-CoV-2…
- Trial name
- NCT05331976
- Testing
- Proof Lab Test System
- Where
- 3 sites in United States
- Volunteers
- 276 people
- Sponsor
- Proof Diagnostics
Extracorporeal Circulation of Blood; Thrombocytopenia
Thrombo-Elastography Guided Management of ECMO
Anticoagulation and coagulation management during ECMO is a challenge. Bleeding and clotting are major sources of morbidity and mortality. The currently used strategies are of poor evidence.
- Trial name
- TEGMO (NCT04268940)
- Testing
- Thromboelastography
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- Damian Ratano
Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection
A Study of the Cobas® Liat CT/NG/MG Test Versus Current Standard Practice for Managing Participants at Increased Risk of Sexually Transmitted Infections
This study is designed to assess the comparative clinical utility of the point of care cobas® liat CT/NG/MG to current standard practices in the diagnosis and treatment of urogenital infections with Chlamydia trachomatis (CT)…
- Conditions
- Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection, Mycoplasma Genitalium Infection
- Trial name
- NCT06369220
- Testing
- cobas® liat CT/NG/MG nucleic acid test, Standard of Care (SOC): Clinician's Standard Practice
- Where
- 4 sites in United States
- Volunteers
- 331 people
- Sponsor
- Hoffmann-La Roche
Osteoporosis
Salivary-based Bone Loss Marker Detection Platform for Point-of-care Screening - Phase II Study
The purpose of this study is to validate a human saliva sample analyzer technique designed to screen for low bone density and osteoporosis.
- Trial name
- NCT02315248
- Testing
- Quantitative computed tomography scan for bone density analysis
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Androgenetic Alopecia
Point-of-Care Adipose-derived Cells for Hair Growth
Androgenetic alopecia (AGA) is the most common form of hair loss and affects 50% and 23% of Caucasian men and women, respectively, over the age of 50.
- Trial name
- ASVF-2016 (NCT02729415)
- Testing
- Stromal Vascular Fraction Cells (SVF Cells) Injection, Liposuction, Hair Measurements
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Florida
Acute Decompensated Heart Failure
Does Ultrasound Assessment for Extravascular Lung Water and IVC Measurement Affect Outcomes in Inpatient Heart Failure Management?
This study evaluates daily POCUS/FCU exams on patients admitted for acute decompensated heart failure with primary end point of acute kidney injury while in hospital.
- Trial name
- NCT04436718
- Testing
- Daily pocus exam
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Riverside University Health System Medical Center
Heart Disease, Lung Disease
Evaluating the Use of Thromboelastography (TEG) in Patient's Requiring Extracorporeal Membrane Oxygenation (ECMO)
This is a pilot study that seeks to evaluate the feasibility and safety of using a TEG algorithm in addition to traditional laboratory tests to guide transfusion and coagulation management of ECMO patients.
- Trial name
- NCT02887820
- Testing
- Thromboelastograph
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stephen Esper
Hemodynamic Assessment, Bedside Ultrasonography
Assessment of LVOT VTI in Healthy Volunteers
Healthy subjects will have transthoracic echocardiography evaluation of Left Ventricular Outflow Tract Velocity-Time Integral (LVOT VTI) performed by operators after brief training.
- Conditions
- Hemodynamic Assessment, Bedside Ultrasonography, Point of Care Ultrasound (POCUS)
- Trial name
- NCT07600931
- Testing
- transthoracic echocardiography
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
HIV
Point-of-care Viral Load Testing Among HIV-infected Adolescents in Haiti
This study is designed as an individual randomized trial among 150 HIV-infected adolescents aged 10-24 years who have been on ART for >6 months and will be randomized in a 1:1 fashion to one of two arms: 1) the intervention arm…
- Trial name
- NCT03288246
- Testing
- point-of-care viral load test
- Where
- Haiti
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
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