Clinical trials: Point-of-Care Systems
This is a Pilot Study Which Aims to Assess the Validity and Applicability of Lateral Flow Assays (LFAs) Which Can be Used as a Point of Care Test for COVID-19, Covid19
The LAVA (Lateral Flow Antigen Validation and Applicability) Study for COVID-19
This is a pilot study which aims to assess the validity and applicability of lateral flow assays (LFAs) which can be used as a point of care test for COVID-19.
- Trial name
- LAVA (NCT04629157)
- Testing
- Innova Lateral Flow Device
- Where
- 2 sites in United Kingdom
- Volunteers
- 400 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Neurodegenerative Diseases, Alzheimer's Disease
Functionalized Point of Care and 3D Printed Dental Aligners as Devices for Early Detection of Neurodegenerative Diseases
The treatment of dementias of neurodegenerative origin is currently limited to symptomatic drugs that are unable to interfere with the underlying mechanisms of neurodegeneration, as the pathological processes leading to dementia…
- Trial name
- PREDICTIVE (NCT07870070)
- Where
- Italy
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Prehospital Emergency Medical Services, Prehospital Emergency Care
The Pre-POCT-Non-Conveyance Trial: Prehospital Point-of-Care Testing to Support Non-Conveyance Decisions
The goal of this clinical trial is to evaluate whether rapid blood tests performed in the ambulance can be implemented in routine prehospital assessment of adults who are initially considered for transport to hospital.
- Conditions
- Prehospital Emergency Medical Services, Prehospital Emergency Care, Point of Care Testing
- Trial name
- NCT07503470
- Testing
- Point-of-care testing (POCT)
- Where
- Denmark
- Volunteers
- 1,500 people
- Sponsor
- Central Denmark Region
Cardiovascular Diseases, Valvular Heart Disease
Reliability of Artificial Intelligence (AI)-Augmented Point-of-care Cardiac Ultrasound in the Hands of Internists
The study aim is to test the diagnostic performance of internists interpreting echo images aided by the AISAP CARDIO V0.7 diagnostic support system.
- Trial name
- NCT05455541
- Testing
- AI augmented POCUS examination
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Endotracheal Tube, Cricoid Cartilage
Point of Care Ultrasound to Confirm Endotracheal Tube Cuff Position in Relationship to the Cricoid in Pediatric Population.
Anatomically, the infra-glottic area (subglottis) and the cricoid ring are the narrowest part of the larynx. In order to limit the incidence of damage related to mucosal pressure injuries from the presence of an endotracheal tube…
- Conditions
- Endotracheal Tube, Cricoid Cartilage, Ultrasound
- Trial name
- NCT04479839
- Testing
- Ultrasound of the airway
- Where
- Qatar
- Volunteers
- 80 people
- Sponsor
- Sidra Medicine
Acute or Programmed Hip Replacement (Gamma Nail, Total Prosthesis or Throuhg DHS) / Knee Surgery
Assessment of Blood Loss With a Point Of Care Device
Main Objective: The purpose of this study is to demonstrate whether there is a correlation between perioperative blood loss and the degree of platelet inhibition assessed by a point of care assay in patients undergoing hip or…
- Trial name
- BLOOD (NCT01430273)
- Where
- 3 sites in France
- Volunteers
- 28 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Immersive Virtual Reality, Discomfort
Effect of a Virtual Reality Program on Patient Comfort in the Surgical Intensive Care Unit
Admission to a surgical intensive care unit (ICU) following major surgery is associated with a number of discomforts, not only related to the disease itself, but also to the care provided or the ICU environment itself (lights…
- Conditions
- Immersive Virtual Reality, Discomfort, IPREA, Intensive Care Unit
- Trial name
- ZION (NCT06830369)
- Testing
- HypnoVR, usual health care
- Where
- France
- Volunteers
- 194 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
HBV Infection, Pregnancy
"HBV unIversal vs Point-Of-Care-based Antiviral treatMent to Prevent Mother-to-child Transmission"
To achieve global elimination of hepatitis B virus (HBV), it is crucial to eliminate HBV mother-to-child transmission (MTCT) by ensuring high coverage of birth dose vaccine and expanding the adoption of peripartum antiviral…
- Trial name
- HIPOCAMP (NCT07054359)
- Testing
- HBsAg RDT Women, Treatment by TDF if HBcrAg RDT positive, Treatment by TDF
- Where
- Vietnam
- Volunteers
- 3,200 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Surgical Site Infection (SSI), Emergency Laparotomies
The Spotlight Study: Early Identification of Post-Surgical Infections Using Bedside Ultrasound.
Introduction: The goal of this observational study is to learn whether point-of-care ultrasound (POCUS) can help detect early fluid build-up under the skin after open abdominal surgery (laparotomy) and whether these findings can…
- Conditions
- Surgical Site Infection (SSI), Emergency Laparotomies, Point of Care Ultrasound (POCUS)
- Trial name
- SPOTLIGHT (NCT07549880)
- Testing
- Point-of-Care Ultrasound (POCUS), Microbiological Wound Swab, ASEPSIS Wound Assessment
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Slagelse Hospital
Colorectal Cancer
Point of Care Faecal Immunochemical Testing for Colorectal Cancer
Blood that can be detected in stool via faecal immunochemical testing is a recognised risk factor for the presence of colorectal cancer. There are a number of point of care faecal immunochemical testing devices available.
- Trial name
- POCFIT (NCT04402424)
- Testing
- Faecal Immunochemical Testing
- Where
- United Kingdom
- Volunteers
- 631 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Yaws
Dual Point-of-care Test for the Diagnosis of Yaws
A dual POC immunoassay simultaneously detecting non-treponemal and treponemal antibodies was developed for the diagnosis of infections with T. pallidum.
- Trial name
- YARADI (NCT01841203)
- Where
- 2 sites in Papua New Guinea
- Volunteers
- 703 people
- Sponsor
- Oriol Mitja
Heart Attack, Stroke
CV Wizard: Does a Clinical Decision Support Tool Improve CVD Risk Factor Control in Safety Net Clinics?
This project aims to reduce disparities in cardiovascular disease (CVD) risk factor control and in rates of heart attacks and strokes among the low-income, racially / ethnically diverse Americans who receive primary care at…
- Conditions
- Heart Attack, Stroke, Cardiovascular Diseases
- Trial name
- CV_WIZARD (NCT03001713)
- Testing
- CV WIZARD
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Sickle Cell Disease (SCD)
Integrating Point of Care Testing (POCT) For Newborn Screening and Early Care for Sickle Cell Disease in Yopougon, Côte d'Ivoire
The goal of this clinical trial is to learn if a multifaceted intervention composed of Gazelle-Multispectral sickle cell disease (SCD) point of care testing (POCT) and early initiation of comprehensive SCD care in children with…
- Trial name
- STEP (NCT07488520)
- Testing
- Gazelle-Multispectral point of care testing for newborn sickle cell disease screening; and initiation of early comprehensive clinical interventions
- Where
- 2 sites in Côte d’Ivoire
- Volunteers
- 120 people
- Sponsor
- Swiss Tropical & Public Health Institute
Acquired Immunodeficiency Syndrome, Histoplasmosis AIDS
Point of Care Tests to Identify Opportunistic Infections in Advanced HIV Patients in Mexico City
In Mexico City, the main cause of mortality among people living with HIV (PLHIV) continues to be opportunistic infections (OIs). Early detection of OIs allows their timely treatment and improves their prognosis.
- Conditions
- Acquired Immunodeficiency Syndrome, Histoplasmosis AIDS, Tuberculosis Infection, Cryptococcal Meningitis
- Trial name
- PREVALIOCDMX (NCT05685641)
- Testing
- Histoplasma Urine Antigen Lateral Flow Antigen test, Cryptococcal Lateral Flow Antigen test, Tuberculosis-lipoarabinomannan Lateral Flow Antigen test
- Where
- 4 sites in Mexico
- Volunteers
- 211 people
- Sponsor
- National Institute of Respiratory Diseases, Mexico
Breast Neoplasms, Lymphoma
Feasibility and Accuracy of Nanosensor-based Cancer Diagnosis at the Point-of-care (Chedza)
Prospective feasibility and validation study of a novel, near-to-care modality for diagnosis of malignancy among cancer suspects.
- Trial name
- Chedza (NCT04119154)
- Testing
- Contrast Microhalography (CEM)
- Where
- Botswana
- Volunteers
- 270 people
- Sponsor
- Harvard School of Public Health (HSPH)
Influenza, COVID-19
Routine Application of Point-of-care PCR Test to Identify and Direct Therapy for Acute Respiratory Infection in the Emergency Department Trial
The RAPID-ARIED Trial is a pragmatic, single-centre, parallel group, open-label, randomised controlled trial to be conducted in the Accident and Emergency Department of Queen Mary Hospital in Hong Kong.
- Conditions
- Influenza, COVID-19, Acute Respiratory Infections (ARIs)
- Trial name
- RAPID-ARIED (NCT06780566)
- Testing
- Point-of-care PCR testing for respiratory viruses, Laboratory PCR testing for respiratory viruses
- Where
- Hong Kong
- Volunteers
- 1,050 people
- Sponsor
- The University of Hong Kong
Low Risk of Preterm Delivery
Medico-economic Impact of Screening Atopobium Vaginae and Gardnerella Vaginalis in Molecular Biology by "Point-of-care" During Pregnancy
Infection is the principal cause of preterm births. Most (90%) women with preterm deliveries have no abnormal history. It is widely agreed that preterm delivery is often associated with bacterial vaginosis.
- Trial name
- AuTop (NCT02288832)
- Testing
- -self-collected vaginal samples, zithromax, usual practices
- Where
- 2 sites in France
- Volunteers
- 6,800 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Shock, Dyspnea
AFrican Resuscitation Ultrasound In Critically-ill Adults
The proposed study is a prospective cohort study in which a select group of emergency physicians at Komfo Anokye Teaching Hospital (KATH) in Ghana will be trained in cardiopulmonary ultrasound (CPUS).
- Trial name
- AFRICA (NCT02794909)
- Testing
- Cardiopulmonary ultrasound exam
- Where
- Ghana
- Volunteers
- 180 people
- Sponsor
- Rockefeller Oteng
Osteonecrosis
Use of Adipose Derived Regenerative Cells in Bilateral Femoral Head Osteonecrosis
This randomized clinical trial aims to determine if cells from a patient's own adipose tissue is safe and capable of helping regenerate the femoral head in patients with osteonecrosis.
- Trial name
- NCT03269409
- Testing
- Lactated Ringers, The Celution 800/GP System (Cytori Therapeutics), Adipose Derived Regenerative Cells (ADRC)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mayo Clinic
SARS-CoV-2, Influenza A
Clinical Validation of the LumiraDx SARS-CoV-2 & Flu A/B Combo Test
This is a prospective multicenter study conducted to evaluate the performance of the LumiraDx SARS-CoV-2 \& Flu A/B tests at point of care sites.
- Conditions
- SARS-CoV-2, Influenza A, Influenza B, Asymptomatic COVID-19
- Trial name
- ITAP1489 (NCT05787444)
- Testing
- LumiraDx SARS-CoV-2 & Flu A/B
- Where
- United States
- Volunteers
- 1,081 people
- Sponsor
- LumiraDx UK Limited
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