Clinical trials: Point-of-Care Systems
Hypotension, Point of Care Ultrasound
Sonography in Hypotension and Cardiac Arrest in the Emergency Department.
This study is designed to determine if there is any relationship between performing an abdominal ultrasound on patients who present with hypotension and their clinical outcomes (as measured by 7, 30 day and discharge mortality).
- Conditions
- Hypotension, Point of Care Ultrasound, Shock
- Trial name
- SHoC-ED (NCT01419106)
- Testing
- Ultrasound (A point of care ultrasound protocol)
- Where
- 6 sites in Canada, South Africa
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Horizon Health Network
COVID-19, Acute Respiratory Infection
Prophylaxis and Treatment of COVID-19
An observation study evaluating physiologic responses and host biomarker expression patterns in early SARS-CoV-2 and acute respiratory infections (ARI) and among their close contacts.
- Trial name
- PROTECT-APT (NCT04844541)
- Where
- 3 sites in United States, Thailand
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Sepsis
Role of Early Point of Care Ultrasound in Management of Sepsis in Emergency Department
Aim of the study is to determine the diagnostic accuracy of point-of-care ultrasound and to determine its role in sepsis management .
- Trial name
- NCT05849194
- Testing
- POCUS examination
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Alexandria University
Acute Heart Failure (AHF), Sarcopenia
Sarcopenia in Older Patients Hospitalized for Acute Heart Failure.
Acute heart failure (AHF) is the leading cause of hospitalization in people over 65, with the group with preserved ejection fraction (HFpEF) being the most closely related to aging.
- Conditions
- Acute Heart Failure (AHF), Sarcopenia, Heart Failure
- Trial name
- MUSICA (NCT07530029)
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Acute Kidney Injury
Point-of-care Ultrasound for Acute Kidney Injury
It is aimed to determine prerenal, renal and postrenal diagnoses of patients with acute kidney injury with POCUS performed in the emergency department.
- Trial name
- NCT04470661
- Testing
- Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Mehmet Ali Aslaner
Congenital Heart Disease
Evaluation of Coagulation Testing in Patients Undergoing Cardiac Surgery
Neonates, children with single ventricle congenital heart disease, and those undergoing multiple complex cardiac surgeries are at high risk of increased perioperative blood loss, and blood product transfusions.
- Trial name
- NCT02410473
- Testing
- Discarded blood samples, Discarded Urine Sample
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
Hepatitis C, Hepatitis C, Chronic
Enhancing Hepatitis C Testing and Treatment Among People Who Inject Drugs Attending Needle and Syringe Programs
This project aims to evaluate two strategies of Hepatitis C virus (HCV) testing compared to standard of care among people who inject drugs at needle and syringe program (NSP) services in Australia, to see if it can improve the…
- Trial name
- TEMPO (NCT04014179)
- Testing
- Xpert HCV Viral Load Fingerstick, Aptima HCV Quant DX Assay
- Where
- 17 sites in Australia
- Volunteers
- 1,801 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Coronavirus, Respiratory Failure
Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19
This is a protocol-driven observational study of lung ultrasound and focused echocardiography images obtained in the Emergency Department (ED) and Intensive Care Unit (ICU) settings as a part of existing standard of care.
- Trial name
- CLUSCO (NCT04379544)
- Testing
- Observation only
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Pennsylvania
Type 2 Diabetes Mellitus
A 6-month Clinical Study to Evaluate the Effect of a Digital Disease Management Tool in Patients With T2DM
Type 2 diabetes mellitus is a complex, chronic disease that requires a comprehensive treatment plan aimed at meeting multitude therapeutic targets associated with micro- and macro-vascular risk reduction.
- Trial name
- NCT03090464
- Testing
- Use of digital disease management tool
- Where
- 46 sites in United States
- Volunteers
- 328 people
- Sponsor
- AstraZeneca
Hepatitis B, Hepatitis B Infection
A Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Sites
A prospective cross-sectional study in which surgically non-invasive sample-taking is done only for the purpose of the study. Capillary (fingerstick) whole blood and EDTA venipuncture whole blood are collected by a healthcare…
- Trial name
- NCT06368466
- Testing
- iStatis HBsAg Test
- Where
- Australia
- Volunteers
- 175 people
- Sponsor
- bioLytical Laboratories
Point of Care Ultrasonography in the Emergency Department.
Initial Patient Evaluation in the Emergency Department With Point-of-Care Ultrasonography
Background: It is well known that emergency physicians can conduct ultrasound examinations as a supplement to initial physical examination.
- Trial name
- NCT02099045
- Testing
- Point of Care Ultrasonography
- Where
- Denmark
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Cancer
Clinical Evaluation of an Investigational Blood Creatinine Point-of-Care Test Device
This study is being done to see if the Nova Creatinine Meter can give a correct measure of creatinine (a blood test used to measure kidney function) when the blood is taken from a capillary (smallest type of blood vessels).
- Trial name
- NCT00607529
- Testing
- hand-held POC creatinine analyzer-blood test
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
General Anaesthesia, Propofol
Blood Propofol Measurement During Anaesthesia Using Propofol Target Controlled Infusion
Propofol is a commonly used agent for sedation and anaesthesia in the intensive care unit and the operating room. The pharmacokinetics of propofol are difficult to predict in patients not conforming to the norms in which the…
- Conditions
- General Anaesthesia, Propofol, Target Controlled Infusion, Pharmacokinetics
- Trial name
- NCT01549639
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Sepsis, Sepsis Bacterial
A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor
The overall purpose of this study is to demonstrate the usability of a clinical-grade device in the form of a finger clasp similar to a pulse oximeter for monitoring lactate values, by comparing its performance in reading…
- Conditions
- Sepsis, Sepsis Bacterial, Lactate Blood Increase, Infectious Disease
- Trial name
- NCT04796285
- Testing
- Lab Clasp
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Syphilis, HIV Infections
Syphilis and HIV Point of Care Testing (POCT) in Saskatchewan
The goal of this clinical trial is to learn about Syphilis and HIV point of care testing among inner city, remote, rural and hard to reach populations in Saskatchewan. The main question[s] it aims to answer are: 1.
- Trial name
- SHIVER (NCT05863117)
- Testing
- Reveal Rapid TP (from MedMira)
- Where
- 2 sites in Canada
- Volunteers
- 1,650 people, healthy volunteers welcome
- Sponsor
- Wellness Wheel Medical Clinic
Effect of NOAC on POCT
Ex-vivo Effect of New Oral Anticoagulants on Point-of-care Devices
Concentration determinations of anticoagulants require plasma instead of whole blood, and results are not immediately available to clinicians.
- Trial name
- NCT01613443
- Volunteers
- 100 people
- Sponsor
- Cardioangiologisches Centrum Bethanien
Image
MRI Gadopiclenol Enhanced Imaging of CNS Tumors
The purpose of this pilot study is to compare a standard of care MRI scan to a non-standard of care MR imaging with portable (0.064 Tesla) MRI following the administration of non-SOC contrast called Gadopiclenol on 10 subjects…
- Trial name
- NCT06127810
- Testing
- CE MRI on 0.064T Scanner, Gadopiclenol
- Sponsor
- Medical University of South Carolina
Platelet Function Tests, Thrombin Generation Tests
Point-of-care Assessment of Thrombin Generation and Platelet Function in Children Requiring Cardiopulmonary Bypass
Coagulopathy after cardiopulmonary bypass (CPB) is associated with increased morbidity and mortality. Clot formation and clot stability are important factors in coagulation and hemostasis.
- Conditions
- Platelet Function Tests, Thrombin Generation Tests, Perioperative Coagulopathy
- Trial name
- NCT02833025
- Testing
- Thrombin generation and Platelet Function Testing
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- The Hospital for Sick Children
Extracorporeal Membrane Oxygenation Complication, Coagulation Factor Deficiency
Evaluation of Coagulation Factors and Point-of-care Devices During Veno-venous ECMO Therapy
Hemorrhagic and thromboembolic complications are common in Veno-venous ECMO therapy. The aim of this study is to provide a detailed analysis of the activity of different coagulation factors and changes in functional coagulation…
- Trial name
- NCT03754868
- Testing
- Detailed coagulation monitoring
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Goettingen
Tuberculosis, Tuberculosis, Pulmonary
Point-of-care Triage Test for Active Tuberculosis
Background: Tuberculosis (TB) is a bacterial lung infection leaving 3.6 million people undiagnosed each year. Thirty percent of infected people do not receive treatment due to failure to receive diagnostic testing or being lost…
- Trial name
- TriageTB (NCT04232618)
- Testing
- Multi-biomarker point-of-care test
- Where
- South Africa
- Volunteers
- 900 people
- Sponsor
- University of Stellenbosch
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