Clinical trials: Point-of-Care Systems
Kaposi Sarcoma
Smartphone Confocal Microscopy for Diagnosing Kaposi's Sarcoma
The investigators propose to evaluate a novel diagnostic approach for Kaposi's sarcoma (KS) that may be eventually deployed with portable, point-of-care techniques. This approach features confocal microscopy.
- Trial name
- NCT03050788
- Testing
- Smartphone confocal microscopy
- Where
- Uganda
- Volunteers
- 363 people
- Sponsor
- Massachusetts General Hospital
Intensive Care (ICU)
Ultrasound vs Chest X-ray for NG Tube Placement in ICU
his study evaluates the diagnostic accuracy of bedside gastric ultrasonography for confirmation of nasogastric tube placement in intensive care unit patients, using chest radiography as the reference standard.
- Trial name
- NCT07376083
- Volunteers
- 170 people
- Sponsor
- Tepecik Training and Research Hospital
SARS (Severe Acute Respiratory Syndrome), Covid19
A Clinical Evaluation of Pine Trees Health Test System Including the Pine Trees Health Reader and COVID-19 Test for Point-of-Care
The scope of this study is to validate the Pine Trees Health COVID-19 Molecular Test with unique clinical specimens from across two (2) geographically diverse point-of-care testing sites in the United States.
- Trial name
- NCT05107258
- Testing
- The Pine Trees Health Test System
- Where
- 3 sites in United States
- Volunteers
- 195 people
- Sponsor
- Pine Trees, Inc.
Vitamine K Antagonist (VKA) Treatment, International Normalized Ratio (INR) Measure at Home
INR at Home Measurement by the LabPad® Point-of-care in Patients on Vitamin K Antagonist Drugs (VKA)
This study evaluates the impact of using LabPad® point-of-care to measure International Normalized Ratio (INR) at home on the patient's follow up on vitamine K antagonist (VKA) treatment during 6 months.
- Conditions
- Vitamine K Antagonist (VKA) Treatment, International Normalized Ratio (INR) Measure at Home, Thromboembolic Pathology
- Trial name
- INRADOM (NCT04117048)
- Testing
- LabPad® point-of-care
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Medicalps
Lower Respiratory Infection, LRTI
Effectiveness of Point-of-care Lung Ultrasound for the Management of Childhood Lower Respiratory Infections
The goal of this clinical trial is to evaluate the effectiveness of point-of-care lung ultrasound versus chest X-ray for the management of childhood lower respiratory infections in a low-resource setting.
- Conditions
- Lower Respiratory Infection, LRTI, Pneumonia, Bronchiolitis
- Trial name
- ELUS (NCT05921526)
- Testing
- Point-of-care lung ultrasound, Chest X-ray (digital images)
- Where
- Nepal
- Volunteers
- 616 people
- Sponsor
- Nagasaki University
Fasting Status
Effect of a Liberal Fasting Regime (Sip-til-Send) on Preoperative Gastric Volume Measured Using Point of Care Ultrasound
Pulmonary aspiration of gastric contents during surgery is a rare but potentially catastrophic event. Current guidelines recommend that patients should fast for six hours for solid food and two hours for clear liquids.
- Trial name
- NCT07656649
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Mother to Child HIV Transmission
Evaluation of Measurement of Maternal Viral Load at Delivery to Optimise Post-natal Prophylaxis of HIV-exposed Newborns
The main objective is to evaluate the operationality of introducing the measurement of viral load in HIV-1 infected mothers at delivery by POC to optimise post-natal prophylaxis and neonatal diagnosis of children according to the…
- Trial name
- IPOP (NCT05017558)
- Testing
- point of care
- Where
- Guinea
- Volunteers
- 70 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Tuberculosis, Pulmonary, Rifampicin Resistant Tuberculosis
GeneXpert Performance Evaluation for Linkage to Tuberculosis Care
The investigators' overall objective is to assess the effectiveness, implementation and costs of a streamlined TB diagnostic evaluation strategy based around rapid, onsite molecular testing.
- Trial name
- XPEL-TB (NCT03044158)
- Testing
- GeneXpert I, Process re-design, Performance Feedback
- Where
- 20 sites in Uganda
- Volunteers
- 10,644 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes
Continuous Glucose Monitoring in Critically Ill
The goal of this clinical research study is to learn if The Guardian® blood-sugar monitoring device can be used reliably in patients with high blood sugar who are receiving care in the ICU.
- Trial name
- NCT00707434
- Testing
- Guardian® blood-sugar monitoring device
- Where
- 6 sites in United States
- Volunteers
- 6 people
- Sponsor
- M.D. Anderson Cancer Center
Artificial Intelligence, Usability
AI-based Informational Assistant for Automated Point-of-care Documentation and Protocol Retrieval
Clinical rounds in the intensive care unit (ICU) involve substantial manual documentation. Retrieving the correct protocol text and structuring notes at the bedside is time-consuming and may contribute to variation in…
- Trial name
- NCT07493616
- Volunteers
- 25 people
- Sponsor
- Willemijn Berkhout
Endotracheal Tube Wrongly Placed During Anesthetic Procedure
Intra-op POCUS for Identification of Endotracheal Tube Position in the Pediatric Population
Chest X-ray and/or fluoroscopy is not routinely used in the OR to confirm endotracheal tube (ETT) placement by anesthesiologists. Multiple studies have shown that ~19% of all intubations result in inappropriate ETT placement.
- Trial name
- POCUS (NCT03031548)
- Testing
- Point-of-care ultrasound exam, Reposition ETT
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Loma Linda University
Influenza, COVID-19
Routine Application of Point-of-care PCR Test to Identify and Direct Therapy for Acute Respiratory Infection in the Emergency Department Trial
The RAPID-ARIED Trial is a pragmatic, single-centre, parallel group, open-label, randomised controlled trial to be conducted in the Accident and Emergency Department of Queen Mary Hospital in Hong Kong.
- Conditions
- Influenza, COVID-19, Acute Respiratory Infections (ARIs)
- Trial name
- RAPID-ARIED (NCT06780566)
- Testing
- Point-of-care PCR testing for respiratory viruses, Laboratory PCR testing for respiratory viruses
- Where
- Hong Kong
- Volunteers
- 1,050 people
- Sponsor
- The University of Hong Kong
Myocardial Infarction
Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Reactivity in Patients With ST-elevation Myocardial Infarction (STEMI)
This is a single-center, randomized, single-blind, investigator-initiated, pharmacological study with a parallel design. Patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention and…
- Trial name
- PRO-GR-4 (NCT01338909)
- Testing
- Prasugrel, Clopidogrel
- Where
- Greece
- Volunteers
- 35 people
- Sponsor
- University of Patras
COVID, SARS-CoV 2
Somerset and South Essex Coronavirus Antigen Testing
This study is to evaluate the utility of the PCL Rapid Antigen Test for Coronavirus (COVID-19) in a real world clinical setting.
- Trial name
- SOCRATES (NCT04403906)
- Testing
- PCL COV05 - COVID 19 Ag Rapid FIA test (Rapid Antigen Test)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Somerset NHS Foundation Trust
NAFLD, Nonalcoholic Fatty Liver
Accurate Point of Care Liver Disease Diagnostics
This research study is being conducted to find out more about techniques to non-invasively evaluate liver disease. The investigators are testing a new technology to evaluate the liver (LiverScope®), and they will compare it to…
- Trial name
- NCT05986916
- Testing
- Liverscope® exam, MR exam, FibroScan® exam (optional)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Murmur, Heart, Innocent Murmurs
Real-World Evaluation of Eko Murmur Analysis Software in a Point of Care Setting
The purpose of this research is to evaluate the impact of Eko AI plus EMAS (Eko Murmur Analysis Software) on a clinician's referral decision in a real-world primary care setting.
- Conditions
- Murmur, Heart, Innocent Murmurs, Heart Murmurs, Pathologic Murmur
- Trial name
- NCT05176899
- Testing
- Use of Eko CORE electronic stethoscope
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Eko Devices, Inc.
Resting Energy Expenditure
Predicting Resting Energy Expenditure in Critically Ill Patients by Measuring Lean Body Mass by US
The study aims to correlate Lean Body Mass (LBM) Evaluated by Musculoskeletal Ultrasound with Resting Energy Expenditure (REE) measured by Indirect Calorimetry and to generate a predictive equation of REE based on LBM, in…
- Trial name
- NCT03193632
- Testing
- US Muscle layer thickness (MLT) estimation, REE estimation by indirect calorimetry
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Eslam Ayman Mohamed Shawki
Hematemesis, Melena
Point of Care Testing of Platelet Function in Patients With Acute Upper Gastrointestinal Bleeding
Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency. In an ageing population, antiplatelet drugs are increasingly being prescribed for treatment and prophylaxis against cardiovascular thrombo-embolic…
- Conditions
- Hematemesis, Melena, Gastrointestinal Hemorrhage, Platelet Dysfunction
- Trial name
- POCGIB (NCT03028064)
- Testing
- blood taking
- Where
- China
- Volunteers
- 476 people
- Sponsor
- Chinese University of Hong Kong
Infection, Bacterial, Antibiotic Resistant Infection
Rapid Test for Detection of the Focus of Infection in Post Neurosurgical Patients.
Background: Due to anatomical restrictions, the inflammatory response to intra-cerebral bacterial infections exposes swollen brain tissues to pressure and ischemia, resulting in life-threatening damage.
- Conditions
- Infection, Bacterial, Antibiotic Resistant Infection, Diagnostic Self Evaluation, Meningitis, Bacterial
- Trial name
- NCT03252028
- Where
- 2 sites in Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fariba Nayeri
Heart Failure Acute, Point-of-care Ultrasound
Simulation-Based Cardiac Point-of-Care Ultrasound Program to Improve Clinical Outcomes in Acute Heart Failure Patients
The aim of this study is to co-design a cardiac POCUS simulation training intervention and implementation strategy for EM clinicians and evaluate the effectiveness of the cardiac point-of-care ultrasound (POCUS) simulation-based…
- Conditions
- Heart Failure Acute, Point-of-care Ultrasound, Simulation Training, Implementation Science
- Trial name
- NCT07592598
- Testing
- Simulation POCUS training, Clinical Practice Guidelines
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Duke University
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