Clinical trials: Point-of-Care Systems
Cardiovascular Diseases
Point-of-Care Ultrasound in Chronic Heart Failure
This study aims to determine whether Point-of-Care Ultrasound (POCUS)-guided treatment is non-inferior to standard NT-proBNP-based care in ambulatory patients following hospitalization for heart failure (HF) over a 12-month…
- Trial name
- POCUS-HF (NCT06887179)
- Testing
- HF focused POCUS, Standard Care (in control arm)
- Where
- Czechia
- Volunteers
- 112 people
- Sponsor
- Masaryk University
Hepatitis C, Hepatitis C, Chronic
Enhancing Hepatitis C Testing and Treatment Among People Who Inject Drugs Attending Needle and Syringe Programs
This project aims to evaluate two strategies of Hepatitis C virus (HCV) testing compared to standard of care among people who inject drugs at needle and syringe program (NSP) services in Australia, to see if it can improve the…
- Trial name
- TEMPO (NCT04014179)
- Testing
- Xpert HCV Viral Load Fingerstick, Aptima HCV Quant DX Assay
- Where
- 17 sites in Australia
- Volunteers
- 1,801 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Risk Reduction
PrEP Point-of-Care Brief-Intervention for Adherence Among Young Men Who Have Sex With Men
Despite advances in HIV prevention, the HIV incidence among young men who have sex with men (YMSM) is increasing, threatening to derail achievement of the United States End the HIV Epidemic goals.
- Trial name
- PrEP2-BAY (NCT05353283)
- Testing
- Motivational Interviewing Counselling, Point-of-care Urine Tenofovir Measurement
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Differentiated Thyroid Cancer, Lymph Node Metastases
Thyroglobulin Point of Care Assay for Rapid Detection of Metastatic Differentiated Thyroid Carcinoma
Background: Despite a favorable prognosis, metastatic cervical lymph nodes (LN), are not uncommon among patients with differentiated thyroid cancer (DTC).
- Trial name
- NCT05078853
- Testing
- Point of care assay for thyroglobulin (POC-Tg) evaluation of a suspected cervical lymph node
- Where
- 5 sites in Israel
- Volunteers
- 250 people
- Sponsor
- Soroka University Medical Center
HIV, PrEP
The ACT-PrEP Study
AIM: To evaluate the integration of point-of-care etiological STI testing, cognitive behavioral counselling (CBC), and sexual partner engagement strategies to improve STI management, PrEP uptake and 3-month PrEP persistence among…
- Conditions
- HIV, PrEP, Acceptability, Appropriateness
- Trial name
- NCT07867990
- Testing
- POC STI testing, CBC, and partner self-testing to improve PrEP uptake and persistence among pregnant and postpartum women., Standard of Care
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Intubation Complication
Diagnostic Accuracy of Core Stethoscope Auscultation vs. Point of Care Ultrasound in Placement of Endotracheal Tube
Misplacement of endotracheal tube (ETT) can have devastating complications for patients, some of which include respiratory failure, atelectasis, and pneumothorax.
- Trial name
- NCT04797520
- Testing
- Eko CORE Stethoscope, Point of care ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
HIV-1
Prevention of Mother-to-child Transmission of HIV-1 Using a Responsive Intervention
The second visit of the Expanded Programme of Immunization when the child is 2 months old (EPI-2) represents a unique opportunity to link the EPI and PMTCT programmes and to introduce preventive and therapeutic rescue…
- Trial name
- PROMISE-EPI (NCT03870438)
- Testing
- Lamivudine Oral Solution
- Where
- 6 sites in Burkina Faso, Zambia
- Volunteers
- 1,506 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Heart Diseases
POC - Transfusion Algorithm Cardiac Study
This multi-centre study will provide sound, generalizable data on the effectiveness of a POC-based algorithm to determine to what extent this guideline can reduce blood product transfusions.
- Trial name
- TACS (NCT02200419)
- Testing
- POC-based transfusion algorithm
- Where
- 12 sites in Canada
- Volunteers
- 7,402 people
- Sponsor
- University Health Network, Toronto
Heart Failure
PRIMARY-HF: Heart Failure Screening in Primary Care Using Point-of- Care
The goal of this clinical trial is to evaluate whether the use of NT-proBNP testing and point-of-care ultrasound (POCUS) can improve the diagnosis and management of heart failure in adults aged 50 years or older with suspected…
- Trial name
- PRIMARY-HF (NCT07711821)
- Testing
- NT-proBNP testing, Cardiac Point-of-Care Ultrasound (POCUS), standard of care
- Where
- 4 sites in Portugal
- Volunteers
- 160 people
- Sponsor
- Universidade do Porto
Training
Feasibility of Point-of-Care Ultrasound Training and Remote Quality Assurance for Community Physicians in Conflict-Affected Syria
Background: POCUS can extend diagnostic capabilities where conventional imaging is unavailable, yet evidence on its implementation in active conflict zones remains scarce.
- Trial name
- NCT07677553
- Testing
- Training in POCUS
- Where
- Israel
- Volunteers
- 9 people
- Sponsor
- Meir Medical Center
Cervical Cancer, HPV Infection
ELEVATE Acceptability Study
This study includes a community-based, two-arm prospective acceptability study, whereby arm 1 consists of an educational session on sexual health and cervical cancer (screening) and a follow-up assessment after 3 months.
- Conditions
- Cervical Cancer, HPV Infection, Acceptability of Health Care
- Trial name
- ELEVATE AS (NCT06136702)
- Testing
- Educational session, Self-sampling, Follow-up assessment
- Where
- 4 sites in Belgium, Brazil and 2 more
- Volunteers
- 1,048 people, healthy volunteers welcome
- Sponsor
- University Ghent
Hypertension, Pregnancy-Induced, HELLP Syndrome
PROTECT-Africa: Biomarker Validation for Preeclampsia Triage
Preeclampsia is a serious high blood pressure condition that can develop during pregnancy. It is one of the leading causes of death and illness for mothers and babies in Africa.
- Conditions
- Hypertension, Pregnancy-Induced, HELLP Syndrome, Eclampsia, Fetal Growth Retardation
- Trial name
- PROTECT-Africa (NCT07810439)
- Where
- Zimbabwe
- Volunteers
- 1,106 people
- Sponsor
- Africa Clinical Research Network (ACRN)
Peripherally Inserted Central Catheters
Point of Care Ultrasound for PICC Line Monitoring Study
A prospective comparative study evaluating chest x-ray determination of PICC line tip location and POC ultrasound PICC line tip location.
- Trial name
- PUP (NCT03954977)
- Testing
- PICC line ultrasound
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Blood Transfusion Complications
Point-of-Care RBC Washing to Prevent Transfusion-Related Pulmonary Complications
This study is designed to determine if point-of-care washing of allogeneic Leukocyte-Reduced Red Blood Cells reduces pulmonary complications when compared to standard-of-care Leukocyte-Reduced Red Blood Cells in a cardiac…
- Trial name
- NCT02094118
- Testing
- Point-of-care washed red blood cell transfusion., Standard of care red blood cell transfusion.
- Where
- 2 sites in United States
- Volunteers
- 171 people
- Sponsor
- Mayo Clinic
Clinical Competence, Ultrasonography
Remote Guidance for eFAST Training Using a Head-Mounted Device
This study looks at the best way to remotely teach and guide doctors-in-training to perform a bedside ultrasound exam called eFAST (extended Focused Assessment with Sonography for Trauma), which is used to quickly check injured…
- Conditions
- Clinical Competence, Ultrasonography, Medical Education, Point-of-care Ultrasound (POCUS)
- Trial name
- Remote-eFAST (NCT07686497)
- Testing
- Standardized instructional eFAST video, Real-time audio remote expert guidance (Microsoft Teams), Head-mounted-device remote expert guidance (Arc 3, RealWear)
- Where
- Switzerland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Philipp Fürnstahl
Syphilis
Point of Care Tests for Syphilis and HIV
This study will evaluate the performance of two point-of-care dual syphilis and HIV tests [Multiplo TP/HIV test (MedMira Inc, Halifax, Nova Scotia) and the INSTI Multiplex HIV-1/HIV-2/Syphilis Antibody Test (bioLytical…
- Trial name
- PoSH (NCT04514848)
- Testing
- INSTI Multiplex HIV-1/2 Syphilis AB test, Multiplo Rapid TP/HIV test
- Where
- Canada
- Volunteers
- 1,526 people
- Sponsor
- University of Alberta
Spinal Puncture, Diagnostic Imaging
Ultrasound-Assisted Lumbar Puncture
Although the lumbar puncture is a common procedure and has been performed without ultrasound for decades, other research studies suggest that there may be some benefits to using ultrasound.
- Trial name
- NCT03167190
- Testing
- Point-of-care ultrasound, Traditional Landmark-based Lumbar Puncture
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Antibiotic Resistant Infection, Critical Illness
CD64 and Antibiotics in Human Sepsis
The purpose of the study is to find out whether CD64 expression on neutrophils measured by a new bedside test (LeukoDx) within 30 minutes is associated with effective antibiotic therapy in critically ill adult patients at risk of…
- Conditions
- Antibiotic Resistant Infection, Critical Illness, SIRS, Sepsis
- Trial name
- CD64SEPLDX (NCT02922998)
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- University of Ulm
Critical Illness, Cardiac Complication
The INSIGHT Feasibility Study Ultrasound in the Intensive Care Unit: A Randomised Controlled Feasibility Trial
Point-of-care ultrasound (PoCUS) is a rapidly evolving method of clinical assessment within the intensive care unit (ICU) with training predominantly aimed at physicians.
- Conditions
- Critical Illness, Cardiac Complication, Pleural Effusion, Consolidation
- Trial name
- INSIGHT (NCT05569798)
- Testing
- Whole body point of care ultrasound scan
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- King's College Hospital NHS Trust
Upper Respiratory Infections
Evaluation of Accuracy and Ease of Use of the FilmArray™ Respiratory Panel (RP EZ) in a CLIA-Waived Clinical Setting
The purpose of this study is to assess the accuracy and ease-of-use of a simplified FilmArray Respiratory Panel test (FilmArray RP EZ) when performed according to the manufacturer's instructions by personnel in laboratories…
- Trial name
- NCT02232711
- Where
- 4 sites in United States
- Volunteers
- 1,082 people
- Sponsor
- BioFire Diagnostics, LLC
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.