Clinical trials: Point-of-Care Systems
Procedural Pain, Procedural Sedation and Analgesia
Effect of Ketamine on Optic Nerve Sheath Diameter During Procedural Analgesia
The goal of this observational study is to learn whether ketamine given for procedural analgesia changes intracranial pressure in adult emergency department patients.
- Conditions
- Procedural Pain, Procedural Sedation and Analgesia, Intracranial Pressure
- Trial name
- NCT07916064
- Testing
- ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ankara Etlik City Hospital
Covid19, Vaccine Refusal
COVID-19 Vaccine Education at the Point of Testing to Increase Vaccine Uptake in Vulnerable Communities in SE Louisiana
This project is a 2-year study to investigate vaccine hesitancy and vaccine completion among vulnerable communities in the Southeastern Louisiana region.
- Conditions
- Covid19, Vaccine Refusal, Vaccine Hesitancy
- Trial name
- NCT04939506
- Testing
- COVID-19 Vaccine Education at the Point of COVID-19 Testing
- Where
- United States
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Respiratory Tract Infections (RTI), Influenza-like Illness
Clinical Assessment of Respiratory Events for Kids: Integrating Diagnostics and Stewardship
This study, called Care4Kids, aims to improve the management of respiratory infections in children visiting emergency departments.
- Conditions
- Respiratory Tract Infections (RTI), Influenza-like Illness, Children
- Trial name
- CARE4KIDS (NCT07453914)
- Testing
- SPOTFIRE R
- Where
- 3 sites in France, Greece and 1 more
- Volunteers
- 720 people
- Sponsor
- BioMérieux
Type 2 Diabetes, Pre-diabetes
Point-of-care Capillary HbA1c Testing for Type 2 Diabetes Screening Among At-risk Individuals in Rural Dali, China
This project aims to compare Point-of-care capillary HbA1c (POC-cHbA1c) testing and fingerstick random blood glucose (RBG) testing in terms of type 2 diabetes detection rate and cost-effectiveness, in order to optimise current…
- Trial name
- NCT07718867
- Testing
- POC-cHbA1c, Fingerstick RBG
- Where
- China
- Volunteers
- 720 people
- Sponsor
- The University of Hong Kong
Coagulopathy
Validation of Point-of-care Thromboelastography (TEG 6s) in Pediatric Patients
The goal of this observational study is to learn about the performance of the TEG6s in normal pediatric patients. The main questions it aims to answer are: What are the normal TEG 6S lab results in normal pediatric patients and…
- Trial name
- NCT05874843
- Testing
- Thromboelastography (TEG 6S)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Indiana University
Traumatic Brain Injury
Evaluation of the Abbott i-STAT TBI Biomarker Test
According to the Centers for Disease Control and Prevention, approximately 200,000 hospitalizations occurred in 2020 related to Traumatic Brain Injury (TBI), which does not include many TBIs treated only in emergency departments…
- Trial name
- NCT06766435
- Testing
- i-STAT TBI Test
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
MASLD, MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease)
Accurate Point of Care Liver Disease Diagnostics (Phase 2)
This research study is being conducted to find out more about techniques to non-invasively evaluate liver disease. This is the second phase of a project in which we are testing a new technology to evaluate the liver…
- Conditions
- MASLD, MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease), NAFLD, NAFLD (Nonalcoholic Fatty Liver Disease)
- Trial name
- NCT07518784
- Testing
- LiverScope® exam, MR exam, Blood draw
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of California, San Diego
Covid19
Leveraging CHWs to Improve COVID-19 Testing and Mitigation Among CJIs Accessing a Corrections-focused CBO
Given the likelihood of COVID-19 remaining an endemic disease among high-risk populations, establishing effective mitigation interventions will be critical to stemming community transmission.
- Trial name
- NCT04878328
- Testing
- Onsite Point-of-care
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Montefiore Medical Center
Infections, Infection, Bacterial
Development and Validation of (Bio)Sensors for the Identification of Pathogens
The recent COVID-19 pandemic has revealed the need to develop tests that are accurate, rapid, and inexpensive for the diagnosis of infectious diseases.
- Conditions
- Infections, Infection, Bacterial, Infection Viral, Infection, Parasite
- Trial name
- NCT06548841
- Testing
- Nanobiotechnology platforms
- Where
- Italy
- Volunteers
- 149 people
- Sponsor
- University of Bologna
Breast Cancer
Tablet-based Mobile Health Ultrasound for Point-of-care Breast Cancer Diagnosis in Nigeria
The purpose of this study is to train Nigerian radiologists to perform ultrasound-guided breast biopsies on women that present to the hospital with a suspicious breast mass.
- Trial name
- NCT04501419
- Testing
- US-guided breast biopsy, Ultrasound-guided breast biopsy training program
- Where
- Nigeria
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Acute Respiratory Tract Infection
PCOT for Outpatients With Acute Respiratory Tract Infection at Risk of Severe Disease in Primary Healthcare
This study aims to evaluate the clinical value of point-of-care multiplex PCR testing (POCT) in guiding early diagnosis and target treatment for acute respiratory infections in primary healthcare settings.
- Trial name
- NCT07159230
- Testing
- point-of-care multiplex PCR test
- Where
- China
- Volunteers
- 16,868 people
- Sponsor
- Capital Medical University
Community-acquired Acute Lower Respiratory Infection
Advanced Diagnostics for Enhanced QUality of Antibiotic Prescription in Respiratory Tract Infections in Emergency Rooms
This study is a randomized controlled trial where participants are randomly assigned in a 1:1 ratio to either a rapid test group or a control group. Standard care is provided in the control group.
- Trial name
- ADEQUATE (NCT04781530)
- Testing
- BioFire FilmArray Respiratory Panel 2.1 plus (RP2.1plus)
- Where
- 6 sites in Germany, Greece and 3 more
- Volunteers
- 522 people
- Sponsor
- PENTA Foundation
Septic Shock
POCUS-Guided Esmolol in Septic Shock: A Pilot RCT
The goal of this pilot clinical trial is to determine if conducting a larger study using point-of-care ultrasound (POCUS) to guide beta-blocker therapy in patients with septic shock is feasible.
- Trial name
- Epic-Beta (NCT07313605)
- Testing
- Esmolol
- Volunteers
- 100 people
- Sponsor
- John Basmaji
Tetanus
TETANUS Antibody Detection in Saliva Study
This study aims to design, develop and optimise a non-invasive, saliva sample-based point-of-care lateral flow test for use in low and middle income settings that can return a qualitative result on whether an individual has or…
- Trial name
- TETANUS (NCT07446166)
- Testing
- Point of care, saliva-based lateral flow test, Blood based immunoassay
- Where
- Rwanda
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
COVID, Coronavirus Infection
Point Of Care UltraSonography for Risk-stratification of COVID-19 Patients
COVID-19 pandemic has developed worldwide in less than 4 months. While most patients have a mild or uncomplicated disease (80%), approximately 15% need hospital care and 5% intensive care.
- Trial name
- POCUSCO (NCT04338100)
- Testing
- Follow-up at 14 days
- Where
- 11 sites in Belgium, France
- Volunteers
- 307 people
- Sponsor
- University Hospital, Angers
The Study Will Focus on Assessing the Survival Benefit on an Enhanced Package of Care for Patients With Advanced HIV Disease
An Enhanced Package of Care to Reduce Reduce Mortality in Advanced HIV Disease
A community-based Phase III, cluster randomized trial that seeks to determine the 24 week survival with retention in care of point of care CD4 testing with visitect and an enhanced package of screening and prophylaxis for…
- Trial name
- ENCORE (NCT05085171)
- Testing
- Enhanced care package
- Where
- Uganda
- Volunteers
- 2,400 people
- Sponsor
- Makerere University
Non-Small Cell Lung Carcinoma (NSCLC)
Improving Clinical Trial Awareness in NSCLC: Pilot Testing A Novel Healthcare IT Platform for Incorporating Education at the Point of Care
The objective of this study is to 1) evaluate the impact of a novel individualized care planning/ educational technology (the On Q Care Planning System or CPS) on oncology patient and provider knowledge, attitudes and beliefs…
- Trial name
- NCT02558998
- Testing
- Survey
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Pharyngitis Acute
Point of Care Streptococcal Pharyngitis Testing
Sore throat is a common problem in children typically caused by viral or bacterial infections. While viral infections resolve without treatment, bacterial infections, such as "strep throat," are treatable with antibiotics.
- Trial name
- NCT03744832
- Testing
- Alere i™ Strep A assay, Throat culture
- Where
- Canada
- Volunteers
- 145 people
- Sponsor
- University of British Columbia
Chronic Kidney Diseases, Kidney Injury, Acute
Clinical Performance of a Point-of-Care Creatinine Testing System in Individuals With Kidney Disease
The goal of this clinical performance study is to evaluate the accuracy and usability of the Eaglenos Creatinine Test System（referred to as EG）, a point-of-care testing (POCT) system that consists of a handheld device and its…
- Trial name
- NCT07251075
- Testing
- Reference Creatinine Test System（Cobas c 111）, Investigational Creatinine Test System （EG）
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tingting Xu
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Diagnosing Obstructive Lung Disease With Point of Care Ultrasound
The objective of this study is to evaluate the diagnostic accuracy of Point of Care Ultrasound (POCUS) in identifying obstructive lung diseases (OLDs), using pulmonary function tests (PFTs) as the gold standard for comparison.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive, Asthma, COPD
- Trial name
- NCT06251271
- Testing
- Point-of-Care Ultrasound
- Where
- Israel
- Volunteers
- 301 people
- Sponsor
- Soroka University Medical Center