Clinical trials: Point-of-Care Systems
Heart Disease
Prediction of Bleeding and Transfusion Outcomes and Assessment of Perioperative Platelet Reactivity in Cardiac Surgery
Excessive bleeding after cardiopulmonary bypass (CPB) operations remains to be a persistent problem. Antiplatelet therapy (APT) is an integral component of perioperative management in patients undergoing cardiac surgery.
- Trial name
- NCT02277379
- Where
- Croatia
- Volunteers
- 113 people
- Sponsor
- University of Zagreb
Pulmonary Embolism, Pulmonary Embolus/Emboli
Point-of-care Ultrasound in Suspected Pulmonary Embolism
Pulmonary embolism (PE) is a common cardiovascular condition with an estimated incidence of 0.60 to 1.12 per 1000 inhabitants in the United States of America, and the diagnosis is challenging as patients with PE present with a…
- Trial name
- NCT04882579
- Testing
- Point-of-care-ultrasound examination
- Where
- 5 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Odense University Hospital
HIV-1
Preventing Childhood HIV: Rescue Intervention. ANRS 12388 PREVENIR-PEV
The second visit of the Expanded Programme of Immunization when the child is 2 months old (EPI-2) represents a unique opportunity to link the EPI and PMTCT programmes and to introduce preventive and therapeutic rescue…
- Trial name
- PREVENIR-PEV (NCT03869944)
- Testing
- Lamivudine Oral Solution
- Where
- Burkina Faso
- Volunteers
- 97 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Visceral Leishmaniasis
Single Dose Liposomal Amphotericin B for Visceral Leishmaniasis
The study is designed to determine the use of delivering point of care, rapid diagnosis with rK39 and treatment with AmBisome single dose of 10 mg/kg when administrated in the Primary Health Center (PHC) settings with regard to…
- Trial name
- NCT01566552
- Testing
- AMBISOME
- Where
- India
- Volunteers
- 1,300 people
- Sponsor
- Banaras Hindu University
Sepsis
Use of Procalcitonin, a Blood Test to Guide Antibiotic Therapy for Sepsis in Adults
Trial design: Randomised controlled, two-arm, parallel, clinical trial to assess the efficacy and safety of sequential daily procalcitonin assessments to guide de-escalation of empirical antibiotic therapy in adult patients with…
- Trial name
- PROCALBAN (NCT05955612)
- Testing
- Procalcitonin measurement
- Where
- Bangladesh
- Volunteers
- 532 people
- Sponsor
- University of Oxford
Left Ventricular Hypertrophy
Point-of-care Ultrasound and Treatment Disparities for Left Ventricular Hypertrophy
The objective of the proposed project is to quantify the prevalence and disparities of undiagnosed left ventricular hypertrophy (LVH) in Emergency Department (ED) patients with persistently elevated asymptomatic BP, and to…
- Trial name
- NCT05730309
- Testing
- Customized discharge and expedited referral instructions
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Yale University
Bowel Obstruction
Diagnostic Performance of Point of Care Ultrasound to Identify Intestinal Obstruction
As reported in previous studies, Point-of-Care Ultrasound (POCUS) has good performance for the diagnosis of bowel obstruction even when compared with CT. This inexpensive, radiation-free tool is available in a majority of ED.
- Trial name
- OCCLUS (NCT04848415)
- Testing
- Point-of-Care Ultrasound
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Nantes University Hospital
Respiration Failure, Diaphragmatic Dysfunction
Dynamic POCUS of Diaphragm Function to Predict Respiratory Failure in Septic Shock
This prospective observational cohort study aims to evaluate the prognostic value of serial bedside ultrasound assessment of diaphragmatic function in adult patients with septic shock.
- Conditions
- Respiration Failure, Diaphragmatic Dysfunction, Mechanical Ventilation, Septic Shock
- Trial name
- POCUS in RF (NCT07820267)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Ischemic Stroke, Atrial Fibrillation
Ischemia Care Biomarkers of Acute Stroke Etiology (BASE)
The proposed study will validate the clinical use of new biomarker blood tests to identify blood components that may differentiate between diverse stroke etiologies and clinical outcomes as listed below: 1.
- Conditions
- Ischemic Stroke, Atrial Fibrillation, Transient Ischemic Attacks, Transient Cerebrovascular Events
- Trial name
- BASE (NCT02014896)
- Testing
- Biomarker blood draw
- Where
- 22 sites in United States
- Volunteers
- 1,750 people
- Sponsor
- Ischemia Care LLC
Surgical Site Infection (SSI), Emergency Laparotomies
The Spotlight Study: Early Identification of Post-Surgical Infections Using Bedside Ultrasound.
Introduction: The goal of this observational study is to learn whether point-of-care ultrasound (POCUS) can help detect early fluid build-up under the skin after open abdominal surgery (laparotomy) and whether these findings can…
- Conditions
- Surgical Site Infection (SSI), Emergency Laparotomies, Point of Care Ultrasound (POCUS)
- Trial name
- SPOTLIGHT (NCT07549880)
- Testing
- Point-of-Care Ultrasound (POCUS), Microbiological Wound Swab, ASEPSIS Wound Assessment
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Slagelse Hospital
Healthy Adults, Venous Leg Ulcer
Pressure and Temperature Sensor for Therapeutic Compression Garments
Pilot study of a soft, flexible pressure and temperature sensor
- Trial name
- NCT03461549
- Testing
- Pressure and Temperature Sensor
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Deep Venous Thromboses, Deep Venous Thrombosis of Left Leg
Point of Care Ultrasound For The Diagnosis Of Deep Venous Thrombosis And Its Effect On Length Of Hospital Stay
This is a Clinical Trial on the use of Point Of Care Ultrasound for the diagnosis of deep venous thrombosis (DVT) and its effect on length of hospital stay.
- Conditions
- Deep Venous Thromboses, Deep Venous Thrombosis of Left Leg, Deep Venous Thrombosis of Right Leg, Deep Venous Thrombosis Proximal
- Trial name
- NCT03038893
- Testing
- Point Of Care Ultrasound (PODUS), Echo Doppler Ultrasound (EDUS)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Nosocomial Pneumonia
The Role of Point-of-care Polymerase Chain Reaction in Managing Nosocomial Pneumonia
The study compares a device that is used for the detection of bacteria and MDR pathogens from skin, soft tissue and nose with the gold-standard (microbiological lab).
- Trial name
- NCT05928208
- Testing
- no intervention
- Where
- Romania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Diabetes Mellitus
Dexcom G6 Intervention Study
The study will assess if Continuous Glucose Monitoring (CGM) represents a better tool to guide healthcare providers in adjusting insulin therapy, by providing a more complete 24-hour assessment of glucose values compared to Point…
- Trial name
- NCT03877068
- Testing
- Dexcom G6 CGM - Continues Glucose Monitoring sensor system, POC BG - Point-of-Care Blood Glucose monitoring
- Where
- 3 sites in United States
- Volunteers
- 185 people
- Sponsor
- Emory University
Dyspnea
Point-Of-Care Ultrasound-Driven vs Standard Diagnostic Pathway in Emergency Department Patients With Dyspnea
The POCUS PATHWAY-trial is a multi-center, randomized, investigator-initiated, open labelled, pragmatic, controlled trial of a point-of-care ultrasound-driven diagnostic pathway vs standard diagnostic pathway in dyspneic…
- Trial name
- POCUS PATHWAY (NCT05674916)
- Testing
- Point-of-care ultrasound-driven diagnostic pathway
- Where
- 9 sites in Denmark
- Volunteers
- 674 people
- Sponsor
- Aarhus University Hospital
Malaria, Diagnoses Disease
Clinical Validation of Novel Malaria Diagnostic Tools for POC Point-of-Care Testing
The aim of this study is to perform a performance evaluation of novel diagnostic tools for detecting malaria in malaria-endemic countries.
- Conditions
- Malaria, Diagnoses Disease, RDT
- Trial name
- NCT06225700
- Where
- Rwanda
- Volunteers
- 509 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Gingivitis, Periodontal Disease
Rapid Point-of-Care Salivary Diagnostic for Periodontal Health
The purpose of this study is to learn if a chair-side testing device will accurately measure levels of a salivary biomarker and thus indicate if a patient has periodontal health, gingivitis or periodontal disease.
- Trial name
- NCT02403297
- Testing
- Quik Check PD
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Innovative Diagnostics Inc
Acute Respiratory Distress Syndrome
Evaluation of POC Lung Ultrasound Combined With Pressure-volume Curve to Titration Adjust PEEP for ARDS Lung Recruitment
Using lung ultrasound re-aeration score(LUS-RAS) combined with pressure-volume curve(PVC) adjust maintain positive end-expiratory pressure(PEEP) after recruitment maneuver, to achieve real-time adjustment, reduce…
- Trial name
- NCT03076450
- Testing
- Lung Ultrasound, Maximum Oxygenation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Pudong New Area Gongli Hospital
SARS CoV-2
A Clinical Evaluation of COVID-19 Rapid Point of Care Antigen Tests
The current standard of care for diagnosis of Severe Acute Respiratory Syndrome associated Coronavirus -2 (SARS-CoV-2 ) infection involves sample collection to be prepared and measured via real time-polymerase chain reaction…
- Trial name
- NCT04568356
- Testing
- Direct Antigen Tests for COVID-19
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- E25Bio, Inc.
Type 1 Diabetes
A Study Comparing Dexcom Continuous Glucose Monitoring to Point of Care Glucose Testing for the Management of Hospital and Post-Discharge Subjects With Type 1 Diabetes
This study aims to compare inpatient glycemic control by measuring the percentage of time in the range of 70-180 mg/dl and the frequency of hypoglycemia between Dexcom G7 Continuous Glucose Monitoring (CGM) and Point of Care…
- Trial name
- NCT06752928
- Testing
- Dexcom G7 rtCGM, Capillary Blood glucose Testing (POC)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
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