Clinical trials: Pollution; Exposure
Exposure to Pollution
Chemometers to Determine the Environmental and Human Exposome by Mixtures of Pollutants
Motivation of this study Human life is full of chemicals: They support the provision of cure, clothes, shelter, transportation and even nourishment of the world population.
- Trial name
- EXPOSO-METER (NCT05927077)
- Testing
- planned surgery for weight reduction
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Helmholtz Centre for Environmental Research - UFZ
Pollution; Exposure
Scalability of a Home Health Navigator Program to Reduce Arsenic, Nitrate, and Lead in Private Well Water
Approximately 34 million Americans rely on private wells to supply their drinking water. Private wells are excluded from the Safe Drinking Water Act.
- Trial name
- NCT05395663
- Testing
- Community health worker
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Acute Coronary Syndrome, Atrial Fibrillation
Short- and Long-term Health Effects of Air Pollution in Poland
The effects of air pollution on the frequency of hospital admissions and mortality due to acute coronary syndromes, atrial fibrillation, and renal disfunction are noted also in areas perceived as pollution-free (due to the lack…
- Conditions
- Acute Coronary Syndrome, Atrial Fibrillation, Kidney Diseases, Particulate Matter Inhalation Injury
- Trial name
- EP-PARTICLES (NCT05198492)
- Testing
- Impact of air pollution
- Where
- Poland
- Volunteers
- 8,300,000 people
- Sponsor
- Medical University of Bialystok
Exposure to Pollution
Responses to Exposure to Low Levels of Concentrated Ambient Particles in Healthy Young Adults
Purpose: To determine whether exposure to levels of fine particles that are close to the current standard will cause cardiovascular changes in healthy individuals.
- Trial name
- RECAP (NCT03232086)
- Testing
- Clean Air, PM2.5
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Risk Factors for Respiratory and Cardiovascular Disease
Influence of Indoor Air Filtration Strategies on Occupant Health Indicators
The purpose of this study is to evaluate whether two different central air purification technologies reduce air pollutant exposure and beneficially influence health as evaluated with a suite of biological markers related to…
- Trial name
- NCT02769208
- Testing
- Central air handling unit air purification technologies
- Where
- China
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Feng Li
Endothelial Dysfunction
Combustion Derived Air Pollution and Vascular Function
Air pollution is a major cause of cardiovascular morbidity and mortality. The components of air pollution responsible and the mechanisms through which they might mediate these harmful effects remain only partially understood.
- Trial name
- NCT00775099
- Testing
- Forearm Vascular Study, Badimon Chamber
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Non-smoking, Healthy Adults
Effect of Short-term Portable Air Purifier Use on Occupant Health Indicators
The purpose of this research project is to examine whether short-term use of portable air pollution filtration can result in changes in indoor airborne pollutants and impact on cardiovascular and respiratory health outcomes of…
- Trial name
- NCT02736487
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Exposure to Environmental Pollution, Non-occupational
The Interaction of Social Factors With Air Pollution
Purpose: The purpose of this protocol is to understand how social factors such as psychosocial stress may modify how people respond to air pollution.
- Trial name
- SOZIAL (NCT02206750)
- Testing
- Clean Air, Ozone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Diet Habit, Pollution; Exposure
Children's Health Study Diet and Air Pollution
This study is built upon the existing data in the Children's Health Study to examine the longitudinal association between childhood exposure to air pollutants and changes in diet among adolescents.
- Conditions
- Diet Habit, Pollution; Exposure, Child Obesity
- Trial name
- CHS DIET (NCT03379298)
- Volunteers
- 3,142 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Respiratory Conditions Due to Unspecified External Agent
Anti-pollution Effects of AP Green Tea Extracts
The objective of this clinical trial is to evaluate the anti-pollution effects of AP green tea extracts in subjects with discomforts related to the respiratory system by prolonged exposure to particulate matter in air pollution
- Trial name
- NCT04340375
- Testing
- AP green tea extracts
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amorepacific Corporation
Gingival Pigmentation, Occupational Heat Exposure
Reducing Gingival Pigmentation Through Workplace Mitigation in Restaurant Oven Workers
Restaurant workers who spend much of their workday near ovens, grills, or other cooking equipment may breathe smoke and experience high heat.
- Conditions
- Gingival Pigmentation, Occupational Heat Exposure, Occupational Air Pollution Exposure
- Trial name
- NCT07805824
- Testing
- Workplace Heat and Air Pollution Mitigation Package, Delayed Workplace Heat and Air Pollution Mitigation Package
- Where
- Iraq
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Salah M. Ibrahim
Tobacco Smoke Pollution
PRIDE: Preventing Respiratory Illnesses During Childhood Study
Environmental tobacco smoke (ETS0, also known as secondhand smoke, is the combination of smoke given off by the burning end of a tobacco product and the smoke exhaled by the smoker.
- Trial name
- PRIDE (NCT00927264)
- Testing
- Motivational Interviewing Intervention for ETS Reduction, Educational Program for ETS Reduction
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Coronary Heart Disease
Controlled Exposures to Air Pollution in Patients With Coronary Heart Disease
Air pollution is a major cause of cardiovascular morbidity and mortality. The components of air pollution responsible and the mechanisms through which they might mediate these harmful effects remain only partially understood.
- Trial name
- NCT00437138
- Testing
- Exposure to dilute diesel exhaust (300µg/m3) or filtered air
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Health Effects of Ambient Air Pollution
Effects of Omega-3 Fatty Acids in Ambient Air Pollution Exposure in Healthy Adults
This observational study recruits healthy individuals who have been routinely taking high amount (at least 3 g/wk) of dietary eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and those who don't, and examines the…
- Trial name
- PISCES (NCT02921048)
- Testing
- omega-3 fatty acids
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- U.S. EPA Human Studies Facility
Asthma, Pollution; Exposure
Residential Ventilation Systems and Filtration for Asthma Control in Adults
The goal of this study was to investigate the effectiveness of three common approaches to upgrading residential mechanical ventilation systems in existing homes for improving asthma-related health outcomes, reducing indoor…
- Trial name
- NCT06098287
- Testing
- Residential mechanical ventilation system (Exhaust), Residential mechanical ventilation system (CFIS) and air filtration upgrades, Residential mechanical ventilation system (ERV) and air filtration upgrades
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Illinois Institute of Technology
Cardiovascular Diseases (CVD), Metabolic Syndrome
Ambient Air and Noise Effect on Cardiovascular Health Risk and Lifestyle Intervention to Attenuate It (METSGREEN)
This study, combining both an observational study and an interventional clinical trial, aims to assess how exposure to ultrafine particulate matter (PM0.1) and noise pollution affects the risk of cardiovascular diseases and…
- Conditions
- Cardiovascular Diseases (CVD), Metabolic Syndrome, Air Pollution Exposure, Environmental Exposure
- Trial name
- METSGREEN (NCT07111208)
- Testing
- Green Space Activity Group - Daily Physical Activity, Mediterranean Diet Group - Dietary Intervention
- Where
- 2 sites in Lithuania
- Volunteers
- 180 people
- Sponsor
- Regina Grazuleviciene
Asthma
Indoor Air Pollution and Children With Asthma: An Intervention Trial
The purpose of this study is to determine whether reducing indoor exposure to NO2 and particles improves respiratory health in children with asthma.
- Trial name
- CAPS (NCT02258893)
- Testing
- NO2 Scrubber, HEPA filter, Control
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Yale University
Healthy Adults
Statins Against Bushfire Smoke
The goal of this clinical trial is to test whether statins can protect the heart and brain from the biological stress and inflammatory responses caused by breathing bushfire smoke in healthy adult volunteers aged 18-64 years.
- Trial name
- SABS (NCT07462715)
- Testing
- Atorvastatin
- Where
- Australia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Menzies Institute for Medical Research
Blood Pressure, Cardiac Ischemia
The Use of L-arginine to Mitigate the Cardiovascular Effects of Exposure to Traffic-related Air Pollution
The present study is aimed to investigate whether oral L-arginine supplementation reduces the adverse cardiovascular effects of exposure to traffic-related air pollution among a group of non-smoking adults with elevated blood…
- Trial name
- NCT03433963
- Testing
- L-Arg supplement
- Where
- 3 sites in China
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Peking University
Air Pollution Exposure, Heart Rate
Assessing the Health Impact of Indoor Air Purification Using Health Data Obtained From Apple Watch Wearers
This study aims to use the Apple Watch health metrics to assess short-term physiological responses in a randomized, double-blind, crossover real-world indoor purification intervention.
- Conditions
- Air Pollution Exposure, Heart Rate, Resting Heart Rate, HRV
- Trial name
- NCT07477834
- Testing
- Real Filtration
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- New York University Abu Dhabi