Clinical trials: Polycystic Ovarian Syndrome (PCOS)
Polycystic Ovary Syndrome
Use of Myo-inositol as Adjuvant Therapy in Patients With Polycystic Ovary Syndrome (PCOS) in Vitro Fertilization (IVF)
The original mechanism of action of myo-inositol and preliminary results available in the literature on its use in IVF suggest its value as adjuvant gonadotropin therapy to reduce the risk of OHSS in PCOS patients.
- Trial name
- FIV-INOPK (NCT02221154)
- Testing
- Inofolic®, Gonadotropins; Folic Acid
- Where
- 4 sites in France
- Volunteers
- 49 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Polycystic Ovarian Syndrome, Hyperandrogenism
Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by Antioxidants
We investigate parameters of hemocoagulation and lipoperoxidation in women using combined oral contraceptives with antiandrogenic activity (containing drospirenone with 20 or 30 mcg ethinylestradiol; or cyproterone acetate)…
- Conditions
- Polycystic Ovarian Syndrome, Hyperandrogenism, Menstrual Irregularities
- Trial name
- NCT02027337
- Testing
- 20 mcg ethinylestradiol /3 mg drospirenone, 20 mcg ethinylestradiol/3 mg drospirenone and Selmevit, 30 mcg ethinylestradiol/3 mg drospirenone
- Where
- Russia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tyumen State Medical University
Polycystic Ovary Disease
"KETOGENIC MEDITERRANEAN VERSUS HYPOCALORIC BALANCED DIET ON POLYCYSTIC OVARIAN ADOLESCENTS"
study was designed to determine the effect of ketogenic Mediterranean diet versus hypocaloric balanced diet on adolescent female with polycystic ovary disease.
- Trial name
- keto- MEDITERR (NCT06610812)
- Testing
- KETOGENIC MEDITERRANEAN diet, hypo-caloric diet:, moderate aerobic exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MTI University
PCOS, Offspring, Adult
Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study
The Offspring Born to Mothers with Polycystic Ovary Syndrome in Guangzhou Cohort study (PCOS-BIG) was established to investigate the short- and long-term effects of intrauterine exposure to maternal PCOS on the health of…
- Conditions
- PCOS, Offspring, Adult, Hyperandrogenism, Epigenetics
- Trial name
- PCOS-BIG (NCT03742011)
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Polycystic Ovary Syndrome
Ovary Syndrome for Efficient Diagnosis and Targeted Therapy
OBJECTIVES: 1. Analysis of DNA methyl transferases (DNMT1, DNMT3A and DNMT3B) and Histone deacetylases (HDAC 1,2,3 and SIRTs) polymorphisms (Somatic and germ line variations). 2.
- Trial name
- PCOS-01 (NCT06102629)
- Testing
- laparoscopy / laparotomy, NO INTERVENTION
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Asian Institute of Gastroenterology, India
Polycystic Ovary Syndrome, Vitamin D Deficiency
Vitamin D Increases Serum Levels of the Soluble Receptor for Advanced Glycation End Products in Women With PCOS
The purpose of this study is to investigate the mechanism that explain the beneficial clinical effect of vitamin D treatment in women with PCOS.
- Trial name
- NCT03644212
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Polycystic Ovary Syndrome
Combined Metformin and Clomiphene Citrate (CC) or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to compare and determine the efficacy of combined metformin and Clomiphene citrate administration to that of laparoscopic ovarian diathermy (LOD) in infertile women with Polycystic ovary syndrome…
- Trial name
- NCT00969631
- Testing
- metformin HCl (Cidophage®; CID,Cairo, Egypt), CC (Clomid®; Global Napi Pharmaceuticals,Cairo, Egypt),Cairo, Egypt), Laparoscopic ovarian diathermy (LOD)
- Where
- Egypt
- Volunteers
- 282 people
- Sponsor
- Mansoura University
Polycystic Ovarian Syndrome
Effects of Traditional Moderate Intensity Training and High Intensity Interval Training in Polycystic Ovarian Syndrome
To determine the comparative effects of traditional moderate intensity training and high intensity interval training on Anxiety, fatigue and Quality of Life in females with polycystic ovarian syndrome
- Trial name
- NCT06303219
- Testing
- RADITIONAL MODERATE INTENSITY TRAINING, HIGH INTENSITY INTERVAL TRAINING
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Quality of Life
Anxiety and Sexual Malfunction Functions in Infertile Pcos Women
Polycystic ovary syndrome (PCOS) is a common hormonal disorder in females in reproductive age associated with signs and symptoms as amenorrhea or oligomenorrhea, obesity,infertility acne and hirsutism tism that mostly Reduce self…
- Trial name
- NCT05056272
- Where
- Egypt
- Volunteers
- 129 people
- Sponsor
- Assiut University
Pre-Eclampsia, Intrauterine Growth Restriction
PEPPI Study: Identification of Women at Risk for Placental Dysfunction
The main purpose of this study is to evaluate Fetal Medicine Foundation's pre-eclampsia risk calculator using maternal characteristics, first trimester serum placental growth factor (PlGF) and mean arterial pressure (MAP) in a…
- Conditions
- Pre-Eclampsia, Intrauterine Growth Restriction, Polycystic Ovary Syndrome, Iron-deficiency
- Trial name
- NCT06115122
- Testing
- Pre-eclampsia screening program
- Where
- Finland
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Polycystic Ovary Syndrome, Infertility
Effect of Progestin-Induced Withdrawal Bleed on Ovulation Induction Cycles With Clomiphene Citrate
Women with polycystic ovary syndrome (PCOS) can suffer from infertility because they do not produce an egg each month, resulting in irregular periods.
- Trial name
- NCT01966575
- Testing
- Progestin
- Where
- Canada
- Sponsor
- University of British Columbia
Polycystic Ovary Syndrome, Insulin Resistance
Effects of Intermittent Fasting on Polycystic Ovary Syndrome (PCOS) Compared to Standard Treatment
The purpose of this study is to assess the effects of Time restricted eating in patients diagnosed with polycystic ovary syndrome, comparing it to the standard hormonal treatment.
- Trial name
- NCT06031753
- Testing
- Time restricted eating
- Where
- Mexico
- Volunteers
- 16 people
- Sponsor
- Instituto Superior de Investigación en Estética Médica, Nutrición y Anti-Envejecimiento
Polycystic Ovary Syndrome
The Effect of Polycystic Ovary Syndrome Treatment on Metabolomics
The aim of this study is to determine the effect of the treatment of polycystic ovary syndrome with two different oral contraceptives that contain cyproterone acetate and drospirenone
- Trial name
- NCT04831151
- Testing
- Yasmin, Diane-35
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Inonu University
Polycystic Ovary Syndrome, Hyperandrogenism
Urinary DENND1A.V2 as a Predictor of Pubertal Hyperandrogenemia
Polycystic ovary syndrome (PCOS) is a common disorder marked by hyperandrogenism, oligo-/anovulation, and subfertility. The precise causes of PCOS are unclear, but the pathophysiology involves complex genetic and environmental…
- Conditions
- Polycystic Ovary Syndrome, Hyperandrogenism, Puberty
- Trial name
- DENND1A (NCT02611128)
- Testing
- Phenotype/genotype assessment
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome
Could the Therapy With Inositol Affect the Cardiovascular Risk in PCOS Women? Results of a Randomized Clinical Trial
Polycystic ovary syndrome (PCOS) is associated with an increased cardiovascular risk. The aim of the study was to evaluate long-term effects of inositol on some cardiovascular risk factors in PCOS patients.
- Trial name
- NCT01574261
- Testing
- Inositol
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Polycystic Ovary Syndrome
A Cooking and Eating Study
Background. The polycystic ovary syndrome (PCOS) is a complex hormonal disorder that presents in susceptible girls around the time of menarche. Females with PCOS have high levels of androgens (e.g., testosterone).
- Trial name
- ACES (NCT01079845)
- Testing
- Nutrition Education, Dietary Counseling, and Cooking
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Boston Children's Hospital
Polycystic Ovary Syndrome
Laparoscopic Ovarian Drilling and Subendometrial Blood Flow
Serum level of total testosterone was measured in the early follicular phase (days 2-4 of spontaneous cycle in oligomenorrhic patients).
- Trial name
- PCOS (NCT03334955)
- Testing
- Laparoscopic ovarian drilling
- Volunteers
- 200 people
- Sponsor
- Zagazig University
Polycystic Ovary Syndrome
Evaluation of Endocrine and Metabolic Parameters in the New Diagnostic Phenotypes of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a very frequent endocrine disease of women in reproductive age, with an estimated prevalence of 5 to 10 % according to the studied population.
- Trial name
- NCT00784615
- Testing
- Blood samples, transvaginal ultrasound
- Where
- Argentina
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Córdoba
PCOS (Polycystic Ovary Syndrome), Insulinemic Response
The Effects Of Low Insulinemic Index Diet On Overweight And Obese Patients With Polycystic Ovary Syndrome
The aim of this study was to investigate the relationship between PCOS and insulinemic index in overweight and/or obese women with PCOS and to evaluate potential beneficial effects on PCOS.
- Trial name
- NCT07124767
- Testing
- 6 weeks of diet with low insulin index diet, 6 weeks of dieting according to TÜBER nutrition recommendations
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Betül Gümüş
Infertility
The Influence of AMH on Ovarian Responsiveness to Ovulation Induction With GnRH in Women With PCOS
The investigator suggests that PCOS women with high AMH levels are resistant to ovarian stimulation and may need adjustment of the dose of gonadotrophin.
- Trial name
- NCT02673632
- Testing
- Merional ®
- Volunteers
- 30 people
- Sponsor
- Ain Shams Maternity Hospital
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