Clinical trials: Polycystic Ovary
Polycystic Ovary Syndrome, Adolescent Behavior
Adolescent Polycystic Ovary Syndrome on a Low-carbohydrate Diet
The aim of the study was to investigate the changes in the clinical and biochemical parameters of adolescents on a low-carbohydrate diet in relation to their PCOS phenotype in the 3rd trimester.
- Conditions
- Polycystic Ovary Syndrome, Adolescent Behavior, Diet Habit
- Trial name
- PCOS (NCT06429618)
- Testing
- Low carbonhydrate diet
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Obstructive Sleep Apnea Syndrome, Polycystic Ovary Syndrome
Effect of Obstructive Sleep Apnea Syndrome on Insulin Sensitivity and Cardiovascular Risk in PCOS Adolescents
Polycystic ovary syndrome (PCOS) is one of the most common disease caused by hormonal imbalance and is also associated with overweight and obesity. It affects 5-10% of adolescent girls and women capable of having children.
- Conditions
- Obstructive Sleep Apnea Syndrome, Polycystic Ovary Syndrome, Sleep Apnea
- Trial name
- NCT01840618
- Testing
- Nasal Continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Pregestational Obesity (BMI > 27kg/m2), History of Polycystic Ovary Syndrome
Medical Nutrition Therapy Plus Transgestational Metformin For Preventing Gestational Diabetes In High Risk Mexican Women
Gestational diabetes mellitus is one of the most frequent complications of pregnancy, that affect between 1 to 14% of population around the world.
- Trial name
- NCT01675310
- Testing
- medical nutrition therapy + metformin, Medical nutrition therapy
- Where
- Mexico
- Volunteers
- 90 people
- Sponsor
- Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Polycystic Ovary Syndrome
Pioglitazone Treatment in Polycystic Ovary Syndrome
In this study, the investigators wish to investigate how pioglitazone treatment effects hirsute women. Hirsute women are often overweight and have an increased amount of male sex hormone in their blood.
- Trial name
- NCT00145340
- Testing
- pioglitazone
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Odense University Hospital
Polycystic Ovary Syndrome
Psychological Traits, Sexuality and Quality of Life in Patients With Polycystic Ovary Syndrome
A prospective assessment of psychological characteristics, quality of life and sexuality in naïve patients.
- Trial name
- NCT03306459
- Testing
- SF-36 (Short Form Health Survey)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Polycystic Ovary Syndrome, Severe Obesity
Effect of Metabolic Surgery on Live Birth Rate of Offspring in Obesity Polycystic Ovarian Syndrome Patients
This is a experimental study, which subjects are obese PCOS patients requiring LSG surgery. Aim to investigate the effects of LSG surgery in PCOS patients whether increases the live birth rate of the offspring.
- Conditions
- Polycystic Ovary Syndrome, Severe Obesity, Laparoscopic Sleeve Gastrectomy
- Trial name
- NCT04151459
- Testing
- Metformin
- Where
- China
- Volunteers
- 18 people
- Sponsor
- RenJi Hospital
Polycystic Ovary Syndrome, Glucose Profile
Glucose Profiles in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome is a very common condition that is associated with metabolic complications. Patients with polycystic ovary syndrome exhibit insulin resistance and are at greater risk to develop type 2 diabetes.
- Conditions
- Polycystic Ovary Syndrome, Glucose Profile, Insulin Resistance, Continuous Glucose Monitoring
- Trial name
- PROGLYSOPK (NCT07483723)
- Testing
- sensor, Age reader
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
PCOS (Polycystic Ovary Syndrome), Obese Adolescents
Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)
This pilot randomized controlled study will plan to enroll 36 adolescent females with Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS) to evaluate the effectiveness and feasibility of a tailored…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Obese Adolescents, Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities, Overweight Adolescents
- Trial name
- Beef+ (NCT07780188)
- Testing
- Beef+
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Texas A&M University
Polycystic Ovary Syndrome
Acupuncture for Insulin Resistance in Women With Polycystic Ovary Syndrome
This two-stage clinical research programme aims to evaluate the preliminary effectiveness and safety of acupuncture for improving insulin resistance in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT07806656
- Testing
- Active Acupuncture, Lifestyle Management
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome, Infertility, Female
GnRH Agonist Plus Hormone Replacement Therapy vs Hormone Replacement Therapy on IVF Outcomes
The study is conducted at Arash Women's Hospital on all women undergoing the frozen embryo transfer cycle. Patients who signed informed consent will be randomly divided into two groups.
- Trial name
- NCT05189873
- Testing
- Long GnRH agonist + HRT, HRT
- Where
- Iran
- Volunteers
- 128 people
- Sponsor
- Tehran University of Medical Sciences
Polycystic Ovary Syndrome
Effects of GLP-1 Analogue Combined With Metformin and Metformin on Gonadal and Metabolic Profiles in Chinese Overweight/Obese PCOS Patients With Hyperandrogenemia.
To study the effects of GLP-1 analogues combined with metformin and metformin on gonadal and metabolic profiles in PCOS patients with BMI ≥ 24 in China. 60 cases of overweight PCOS patients were collected from Shengjing hospital.
- Trial name
- NCT04969627
- Testing
- Metformin, Exenatide
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Bing He
PCOS
Cabergoline & Letrozole Versus Letrozole in Ovulation Induction in PCOS
Does combined Cabergoline and letrozole increase ovulation rate What medical problems do participants have when taking drug Cabergoline and Letrozole ? Researchers will compare drug combination of Cabergoline and letrozole to…
- Trial name
- PCOS OID (NCT07255911)
- Testing
- Letrozole 0.5mg, Cabergoline 0.5 mg
- Where
- Bangladesh
- Volunteers
- 72 people
- Sponsor
- Mst.Sumyara Khatun
Polycystic Ovary Syndrome, Dietary Habits
Comparison of Lifestyle Markers Between Women With and Without Polycystic Ovary Syndrome
The purpose of the study is to identify lifestyle factors associated with PCOS and understand how diet and activity levels impact features of PCOS.
- Conditions
- Polycystic Ovary Syndrome, Dietary Habits, Physical Activity
- Trial name
- NCT01859663
- Where
- 3 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Cornell University
PCOS GnRH Antagonist and GnRH Agonist IVF/ICSI Cycles, IVF Outcomes
Effect of Estradiol Pretreatment on Follicular Synchronization and IVF Outcomes in Women With Polycystic Ovary Syndrome Undergoing ICSI Using GnRH Antagonist Protocol
This randomized clinical trial included 60 infertile women diagnosed with PCOS undergoing ICSI cycles using a GnRH antagonist protocol.
- Trial name
- NCT07727863
- Testing
- GnRH Antagonist Protocol, Estradiol Valerate 4mg
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University
Polycystic Ovarian Syndrome
Sitagliptin or BeiDouGen Capsule Improve the Pregnancy Outcome in Patients with PCOS
This study will be carried out under the guidance of professional doctor, patients with PCOS will be treated with Sitagliptin or BeiDouGen capsule or both two to assess their ovarian function and reproductive outcomes, and…
- Trial name
- NCT06587698
- Testing
- Sitagliptin, BeiDouGen, Sitagliptin+BeiDouGen
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Polycystic Ovarian Syndrome, Subfertility
Comparison Between the Role of Follicular Output Rate and Preovulatory Count in the Prediction of Pregnancy in Women With Polycystic Ovarian Syndrome Undergoing Intra Cytoplasmic Sperm Injection (ICSI)
Our study is observational, we are observing data from routine measurements during IVF/ICSI. Our study does not assess IVF/ICSI as an intervention, we are evaluating the role of FSI and preovulatory count which are calculated by…
- Conditions
- Polycystic Ovarian Syndrome, Subfertility, ICSI
- Trial name
- NCT02190006
- Where
- 2 sites in Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome Health-related Quality of Life
Translation and Validation of the French mPCOSQ (mPCOSQ-F).
This study is a prospective, observational, bicentric study, evaluating the validity and reliability of a French version of the mPCOSQ questionnaire (mPCOSQ-F), used to assess health-related quality of life (HRQOL) in women with…
- Trial name
- NCT07016035
- Testing
- mPCOSQ-F and SF-36
- Where
- France
- Volunteers
- 350 people
- Sponsor
- CHU de Reims
Polycystic Ovary Syndrome, Dental Caries
Oxidative Stress in Polycystic Ovary Syndrome With Periodontal Disease and Dental Caries Lesions
This study evaluates the oxidative stress parameters in females with polycystic ovary syndrome (PCOS) and clinically healthy. Because of the fact that both oral disease included periodontitis and dental caries, and metabolic…
- Trial name
- NCT03594968
- Testing
- polycystic ovary syndrome
- Where
- Turkey (Türkiye)
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Polycystic Ovary Syndrome (PCOS), Myo-inositol
Myo-Inositol and D-Chiro-Inositol for Menstrual Irregularities and Hormone Changes in Women With Polycystic Ovarian Syndrome
The goal of this clinical trial is to determine whether a combination of myo-inositol (MI) and D-chiro-inositol (DCI) with folic acid is more effective than placebo (Folic acid alone) in improving menstrual irregularities and…
- Conditions
- Polycystic Ovary Syndrome (PCOS), Myo-inositol, D-chiro-inositol
- Trial name
- NCT07701525
- Testing
- Myo-Inositol and D-Chiro-Inositol Combination Therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Polycystic Ovarian Syndrome (PCOS), Pregnancy Outcomes
Comparison of Pregnancy Outcomes in Women with Polycystic Ovarian Syndrome with and Without Glucophage
The goal of this clinical trial is to learn if Glucophage (metformin) improves pregnancy outcomes in women with polycystic ovarian syndrome (PCOS). It will also evaluate the safety of Glucophage during pregnancy.
- Trial name
- NCT06713967
- Testing
- Metformin (Glucophage), Standard Care (Diet and Exercise Only)
- Volunteers
- 70 people
- Sponsor
- University of Health Sciences Lahore