Clinical trials: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) Women
Meal Timing on Glucose and Hyperandrogenism in PCOS Women
The objective of this study is to investigate the effects of two isocaloric maintenance diets with different meal timing distribution on insulin resistance hyperandrogenism and cytochrome P450c17 alpha activity in lean PCOS…
- Trial name
- MealTimePCOS (NCT01711476)
- Testing
- Active Comparator: Lifestyle counseling ARM 1
- Where
- Venezuela
- Volunteers
- 60 people
- Sponsor
- Hospital de Clinicas Caracas
Polycystic Ovary Syndrome, Puberty Disorders
Does Treatment of Androgen Excess Using Spironolactone Improve Ovulatory Rates in Girls With Androgen Excess?
Adolescent girls with androgen excess have a higher rate of irregular periods and decreased ovulation rates compared to normal girls, and are considered at-risk for developing polycystic ovary syndrome (PCOS).
- Conditions
- Polycystic Ovary Syndrome, Puberty Disorders, Ovulation Disorder
- Trial name
- CBS009 (NCT04075149)
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome, Infertility
Clomiphene Citrate Plus uFSH Versus Aromatase Inhibitor Plus uFSH in Clomiphene Resistant Infertile PCOS Women
Polycystic ovarian syndrome (PCOS) is a condition characterized by infertility, infrequent periods and amenorrhea or irregular bleeding plus anovulatory infertility.
- Trial name
- NCT01793038
- Testing
- Aromatase inhibitor (litrezole) plus uFSH arm, clomiphene citrate-uFSH arm
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Mansoura Integrated Fertility Center
Polycystic Ovary Syndrome (PCOS)
App Impact on Quality of Life and Symptoms in PCOS
This study investigates the influence of a PCOS app on the quality of life and symptoms of individuals with polycystic ovary syndrome (PCOS).
- Trial name
- NCT06912594
- Testing
- PCOS-App
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- Endo Health GmbH
Polycystic Ovary Syndrome
Oral Administration of DCI to Women With PCOS
To determine if oral DCI administration to women with PCOS increases the total DCI content in urine and blood, and, if so, if that change is accompanied by i) an increase in DCI-IPG release in blood (as determined by bioactivity)…
- Trial name
- PCOS (NCT00497653)
- Testing
- DCI
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Virginia Commonwealth University
Polycystic Ovary Syndrome
Metformin and Lifestyle Intervention in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome is a frequent cause of abnormal menses and infertility. It has also been related to cardiovascular disease.
- Trial name
- NCT00679679
- Testing
- Metformin
- Where
- Argentina
- Volunteers
- 30 people
- Sponsor
- Hospital Privado de Cordoba, Argentina
Obesity, Polycystic Ovary Syndrome
Effect of Diet Plus Sibutramine on Hormonal and Metabolic Features in Overweight and Obese Women With PCOS
Studies on the effect of sibutramine, an anti-obesity drug, on hormonal and metabolic features of women with polycystic ovary syndrome (PCOS) are lacking.
- Trial name
- NCT00463112
- Testing
- Sibutramine
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hippocration General Hospital
Polycystic Ovarian Syndrome, Obesity, Abdominal
Acupuncture in the Regulation of Dai Meridian for Polycystic Ovarian Syndrome Patients With Abdominal Obesity
The purpose of this study is to determine whether the use of electroacupuncture to dredge and regulate Dai Meridian combined with lifestyle modification are more effective than lifestyle modification only in the treatment of…
- Trial name
- NCT02785965
- Testing
- electroacupuncture, lifestyle modification
- Where
- 2 sites in China
- Volunteers
- 84 people
- Sponsor
- Dongfang Hospital Beijing University of Chinese Medicine
Poly Cystic Ovary Syndrome
Inspiratory Muscle Training for the Management of Polyendocrine Metabolic Ovarian Syndrome
Inspiratory muscle training (IMT) is a relatively simple and accessible form of exercise that specifically targets the respiratory muscles and has been reported to improve inspiratory muscle strength, respiratory efficiency…
- Trial name
- NCT07871175
- Testing
- Exercise
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Polycystic Ovary Syndrome
OCP vs Metformin for Improvement in Clinical Symptoms and Metabolic Markers in Indian PCOS Women
Objective: To assess effectiveness of ISD (Insulin sensitizing drugs) Vs OCP (Combined E\&P cyproterone acetate) in improving clinical, hormonal and metabolic features of PCOS( polycystic ovary syndrome)women from India.
- Trial name
- OCP (NCT02744131)
- Testing
- Oral contraceptive pill combination of ethyl estradiol and Cyproterone acetate, Metformin 1500mgs per day
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Kar Clinic & Hospital Pvt. Ltd.
Polycystic Ovary Syndrome
N-acetyl Cysteine and Clomiphene Citrate or Metformin and Clomiphene Citrate for Women With CC Resistant Polycystic Ovary Syndrome (PCOS).
The purpose of this study is to compare and determine the efficacy of combined N-acetyl cysteine and clomiphene citrate(CC)with combined metformin and CC in infertile women with Polycystic ovary syndrome(PCOS)not responding to…
- Trial name
- NCT01008046
- Testing
- combined N-acetyl cysteine -CC, combined metformin-CC
- Where
- Egypt
- Volunteers
- 192 people
- Sponsor
- Mansoura University
Polycystic Ovary Syndrome
AMH for the Identification of PCOM in PCOS Diagnosis
The purpose of this study is to validate the anti-müllerian hormone (AMH) cut-off established and validated in the APHRODITE study, for the determination of PCOM as part of the diagnosis of PCOS, using the Elecsys AMH Plus…
- Trial name
- HARMONIA (NCT05527353)
- Where
- Finland
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Voice Change
Voice Analysis in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting up to one in five reproductive-aged women. It is associated with clinical and/or biochemical hyperandrogenism, oligomenorrhea, and polycystic appearance of…
- Trial name
- NCT06085170
- Testing
- Acoustic Analysis by MDVP
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Minia University
Polycystic Ovary Syndrome
L-Carnitine and Clomiphene Citrate for Induction of Ovulation in Women With Polycystic Ovary Syndrome
The purpose of the study to assess the efficacy of adding L-carnitine to clomiphene citrate for increasing the ovulation and the pregnancy rate in women with PCOS.
- Trial name
- NCT03476356
- Testing
- oral clomiphene citrate, oral carnitine supplementation
- Where
- Egypt
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome, Cardiovascular Disease
LIPT - Liraglutide in Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) affects 5-10% of women in fertile age. PCOS is associated with metabolic syndrom, diabetes and and increased risk og cardiovascular disease.
- Trial name
- LIPT (NCT02073929)
- Testing
- Liraglutide for 26 weeks
- Where
- 3 sites in Denmark
- Volunteers
- 72 people
- Sponsor
- Jens Faber
PCOS- Polycystic Ovary Syndrome
The Synbiotics Effects in Polycystic Ovary Syndrome: A Randomized Controlled Trial
The goal of this clinical trial is to compare the effect of synbiotics and placebo in Thai women with polycystic ovary syndrome.
- Trial name
- PCOS (NCT06169566)
- Testing
- synbiotics
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maharaj Nakorn Chiang Mai Hospital
Polycystic Ovary Syndrome
Role of Insulin Action and Free Fatty Acids in Hyperandrogenism of Women With Polycystic Ovary Syndrome
The investigators hypothesis is that free fatty acids (FFA) accumulation in non fatty tissues would lead to insulin resistance and hyperandrogenism in PCOS women.
- Trial name
- NCT01019356
- Testing
- Rosiglitazone, Acarbose
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Jean-Patrice Baillargeon
Polycystic Ovary Syndrome, Obesity
Effect of Berberine on Hormonal and Metabolic Features in Obese Women With Polycystic Ovary Syndrome (PCOS)
Berberine has showed effective in lowering blood sugar levels in db/db mice and anti-dyslipidemia in human.Studies on the effect of berberine on metabolic and hormonal features of women with polycystic ovary syndrome (PCOS) are…
- Trial name
- NCT01138930
- Testing
- Berberine
- Where
- 4 sites in China
- Volunteers
- 120 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Polycystic Ovary Syndrome (PCOS) With Concurrent Nonalcoholic Fatty Liver Disease (NAFLD)
Evaluation of the Therapeutic Effects of Curcumin on Changes in Lipid, Metabolic, and Hormonal Profiles, Liver Enzyme Activity, and Ultrasonography Morphology of the Liver in Women With Polycystic Ovary Syndrome and Nonalcoholic Fatty Liver Disease: A Double-blind, Placebo-controlled Clinical Trial
Background and Objectives: Polycystic ovary syndrome (PCOS) and nonalcoholic fatty liver disease (NAFLD) commonly co-occur and are associated with insulin resistance, chronic inflammation, and metabolic and hormonal imbalances.
- Trial name
- NCT07278128
- Testing
- Patients (women of reproductive age suffering from non-alcoholic fatty liver with polycystic ovary syndrome) receiving 500 mg curcumin capsules (prepared from the extraction of turmeric in the laborat
- Where
- Iran
- Volunteers
- 74 people
- Sponsor
- Fateme Moshirenia
Polycystic Ovary Syndrome
Metabolic Disturbances in Polycystic Ovary Syndrome (PCOS)
The scope of the study was to investigate different metabolic aspects that may lead to or are a consequence of insulin resistance in premenopausal women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT00606671
- Where
- Denmark
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
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