Clinical trials: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
Myo-Inositol for Ovarian Stimulation and ICSI Outcomes in Women With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder that may affect ovarian function, insulin sensitivity, and fertility.
- Trial name
- NCT07779850
- Testing
- Myo-Inositol, Folic Acid
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Kafrelsheikh University
Polycystic Ovary Syndrome
Letrozole Versus Chinese Herbal Medicine on Polycystic Ovary Syndrome (PCOS)
This is a multicenter double-blind randomized controlled trial. A total of 420 anovulatory Chinese women with PCOS will be recruited, and the randomization will be stratified by each participating site.
- Trial name
- NCT01431352
- Testing
- Letrozole
- Where
- 18 sites in China
- Volunteers
- 420 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Infertility
Influence of a Prematuration Culture With a Phosphodiesterase-3 Inhibitor (PDE3-I) on Embryonic Aneuploidy Rate and Developmental Potential
A single centre randomised controlled trial investigating the influence of a novel prematuration system (PMS) using a phosphodiesterase-3 inhibitor for in-vitro maturation of oocytes - pilot study.
- Trial name
- NCT00822874
- Testing
- prematuration culture
- Where
- Belgium
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Polycystic Ovary Syndrome
Resting Metabolic Rate, Fat Distribution, Endocrine and Metabolic Features in Polycystic Ovary Syndrome
In a longitudinal, prospective and observational study, patients with PCOS and controls wore the SenseWear Armband for 2 days. Resting metabolic rati (kcal/die), total energy expenditure (MET, kcal) were evaluated.
- Trial name
- NCT03132545
- Testing
- SenseWear Armband (SWA) monitoring, total body dual-energy X-ray absorptiometry
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Induction of Ovulation, PCO - Polycystic Ovaries
Sodium-Glucose Co-Transporter-2 Inhibitors as Adjuvant Therapy With Letrozole in Induction of Ovulation in Women With Polycystic Ovarian Syndrome
The aim of the study is to assess the efficacy of adjuvant therapy dapagliflozin, metformin as monotherapy and combination of both in comparison to control group in induction of ovulation with letrozole in women PCOS, focusing…
- Trial name
- SGLT-2/PCOS (NCT07589075)
- Testing
- Metformin 1000 mg Oral Tablet, Dapagliflozin 10 MG Oral Tablet [Farxiga], Combined Dapagliflozin-Metformin 5/1000mg
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Reproductive Age, PCOS (Polycystic Ovary Syndrome)
Functional Proteins in Polycystic Ovary Syndrome
The concentration of functional proteins: kisspeptin, ghrelin, zonulin will be measured and compared in women with polycystic ovary syndrome (PCOS) and insulin resistance (IR), in women with PCOS without IR, and in women without…
- Trial name
- NCT06793098
- Testing
- Measurement of kisspeptin concentration, Measurement of ghrelin concentration, Measurement of zonulin concentration
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Polycystic Ovary Syndrome
A Study of Safety and Efficacy of Tildacerfont in Females With Polycystic Ovary Syndrome and Elevated Adrenal Androgens
An investigation of the safety and efficacy of tildacerfont in women with PCOS and elevated adrenal androgens
- Trial name
- NCT05370521
- Testing
- Tildacerfont
- Where
- 21 sites in United States
- Volunteers
- 27 people
- Sponsor
- Spruce Biosciences
Weight Loss, Anovulation
Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss
The objective of this study is to explore the effects of weight loss on body composition, metabolic status, reproductive hormones, and ovarian follicle development in obese women with regular menstrual cycles versus obese women…
- Conditions
- Weight Loss, Anovulation, Amenorrhea, Infertility
- Trial name
- NCT01785719
- Testing
- Commercial Weight Loss Program
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Cornell University
PCOS
Comparison of Myoinositol and Metformin in PCO
Aim of the study is to compare the effect of myoinositol and metformin in the resumption of the spontaneous menstrual cycle in patients diagnosed with PCOS or having oligo/amenorrhea, reduction in weight and BMI, Improvement in…
- Trial name
- PCO (NCT04204044)
- Testing
- Metformin Hydrochloride, Myo-inositol
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Rashid Latif Medical College
Polycystic Ovary Syndrome
The Effect of Escitalopram in PCOS
In a randomized study the investigators aim to characterize the effect of antidepressive medicine on quality of life, body composition, adrenal activity and glucose metabolism in PCOS.
- Trial name
- NCT05840692
- Testing
- Escitalopram 20 mg
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Non-alcoholic Fatty Liver Disease in Women With PCOS
Saroglitazar Magnesium 4 mg in the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in Women With PCOS (EVIDENCES VII)
This is a multicenter, phase 2A, randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of Saroglitazar Magnesium in women with well characterized PCOS.
- Trial name
- NCT03617263
- Testing
- Saroglitazar Magnesium 4 mg Tablet
- Where
- 19 sites in United States, Mexico
- Volunteers
- 60 people
- Sponsor
- Zydus Therapeutics Inc.
Obesity, Polycystic Ovaries Syndrome
The Effect of Weight Loss on Anti-Müllerian Hormone Levels in Women With Polycystic Ovary Syndrome (PCOS)
The first aim of the investigators study, was to investigate the combined effect of diet,physical exercise and orlistat, for 24 weeks, on serum Anti-Müllerian Hormone (AMH) levels in obese women with polycystic ovary syndrome…
- Trial name
- NCT01475019
- Testing
- Orlistat, Sibutramine, Diet and physical exercise
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- Aristotle University Of Thessaloniki
PCOS (Polycystic Ovary Syndrome)
Optimal Allogeneic PRP Concentration for Oocyte In Vitro Maturation in Women With PCOS
In vitro maturation is a long-studied technique used to obtain mature oocytes outside the human body. However, this method can increase the risk of ovarian hyperstimulation syndrome (OHSS), particularly in patients with…
- Trial name
- NCT07514234
- Testing
- PRP plasma rich platelets
- Where
- Indonesia
- Volunteers
- 15 people
- Sponsor
- Gadjah Mada University
Polycystic Ovary
Serum Fetuin Level in Polycystic Ovary Syndrome
polycystic ovary syndrome is a common gynecological problem
- Trial name
- NCT03819998
- Testing
- measurement of Fetuin-A level in serum
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
PCOS GnRH Antagonist and GnRH Agonist IVF/ICSI Cycles, IVF Outcomes
Effect of Estradiol Pretreatment on Follicular Synchronization and IVF Outcomes in Women With Polycystic Ovary Syndrome Undergoing ICSI Using GnRH Antagonist Protocol
This randomized clinical trial included 60 infertile women diagnosed with PCOS undergoing ICSI cycles using a GnRH antagonist protocol.
- Trial name
- NCT07727863
- Testing
- GnRH Antagonist Protocol, Estradiol Valerate 4mg
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome, Infertility
Effect of Progestin-Induced Withdrawal Bleed on Ovulation Induction Cycles With Clomiphene Citrate
Women with polycystic ovary syndrome (PCOS) can suffer from infertility because they do not produce an egg each month, resulting in irregular periods.
- Trial name
- NCT01966575
- Testing
- Progestin
- Where
- Canada
- Sponsor
- University of British Columbia
Polycystic Ovary Syndrome
Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients.
To study the effects of pioglitazone combined with metformin and metformin on gonadal and metabolic profiles in PCOS patients with BMI < 24 in China. 60 cases of nonobese PCOS patients were collected from Shengjing hospital.
- Trial name
- NCT05519813
- Testing
- Metformin, Pioglitazone Hydrochloride And Metformin Hydrochloride Tablets
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Bing He
Polycystic Ovarian Syndrome (PCOS), Infertility
Letrozole Step up Protocol for Ovulation Induction in Infertile Women With Polycystic Ovary Syndrome
The goal of this clinical trial is to learn if drug letrozole in step up dose works better to treat anovulation in infertile women with polycystic ovary syndrome.
- Trial name
- NCT07143682
- Testing
- Letrozol step up dose, Conventional fixed dose letrozole
- Where
- Bangladesh
- Volunteers
- 70 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Polycystic Ovary Syndrome (PCOS)
Appetite Response to Meals With Different Protein Sources in Women With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by insulin resistance, hyperandrogenism, and reproductive dysfunction.
- Trial name
- NCT07142603
- Testing
- Metabolic response to protein source
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas, Fayetteville
PCOS, Obesity
Polycystic Ovary Syndrome and Liraglutide
The purpose of this study was to determine whether liraglutide is more effective than metformin in the treatment of obese women with newly diagnosed polycystic ovary syndrome (PCOS).
- Trial name
- NCT01899430
- Testing
- liraglutide, metformin
- Where
- Slovenia
- Volunteers
- 32 people
- Sponsor
- University Medical Centre Ljubljana
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