Clinical trials: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
Serum Metabolomics Study of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a complex, heterogeneous disorder, which produces in 5-20% reproductive age women. In this study, a nontargeted metabolomics approach based on ultra high-performance liquid chromatography…
- Trial name
- NCT03618342
- Where
- China
- Volunteers
- 1,272 people, healthy volunteers welcome
- Sponsor
- Heilongjiang University of Chinese Medicine
Menorrhagia, Endometrial Neoplasms
Evaluation of the Goldstein SonoBiopsy™ Catheter for Diagnosing Endometrial Pathology
To assess the adequacy of an endometrial biopsy sample obtained using sonohysterography.
- Conditions
- Menorrhagia, Endometrial Neoplasms, Polycystic Ovary Syndrome, Uterine Neoplasms
- Trial name
- NCT01969396
- Testing
- SonoBiopsy Catheter, Endometrial biopsy catheter
- Where
- Panama
- Volunteers
- 2 people
- Sponsor
- Cook Group Incorporated
Unexplained Infertility, Polycystic Ovarian Syndrome
Nimodipine to Prevent LH Surge During Ovulation Induction: Blinded Placebo-controlled RCT
The main purpose of this study is to test the effectiveness of nimodipine in preventing a luteinizing hormone (LH) surge in women undergoing ovulation induction with clomiphene citrate.
- Conditions
- Unexplained Infertility, Polycystic Ovarian Syndrome, Anovulatory
- Trial name
- NIMO (NCT01672801)
- Testing
- Nimodipine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boston IVF
PCOS
PCOS and Brain Health
The purpose of this study is to determine how polycystic ovary syndrome (PCOS) impacts overall brain health, such as cerebral blood flow (CBF), brain structure and connectivity, and cognitive performance.
- Trial name
- NCT07727512
- Testing
- MRI Visit, Laboratory Visit
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Polycystic Ovary Syndrome
Minimal Stimulation or Clomiphene Citrate in Treatment of Polycystic Ovary Syndrome
The purpose of this study is to compare and determine the the efficacy of minimal stimulation and clomiphene citrate(CC) as the first-line treatment in infertile women with Polycystic Ovary Syndrome(PCOS).
- Trial name
- NCT01157312
- Testing
- clomiphene citrate +highly purified uFSH, clomiphene citrate
- Where
- Egypt
- Volunteers
- 113 people
- Sponsor
- Mansoura University
Polycystic Ovarian Syndrome in Adolescent Females, Vitamin D Deficiency
Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)
This study is a double blind, placebo controlled, randomized trial of study subjects with PCOS and low vitamin D to 2 groups- placebo and vitamin D replacement.
- Trial name
- NCT04355572
- Testing
- Vitamin D 4000IU daily
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Polycystic Ovary Syndrome, Vitamin D Deficiency
Vitamin D Increases Serum Levels of the Soluble Receptor for Advanced Glycation End Products in Women With PCOS
The purpose of this study is to investigate the mechanism that explain the beneficial clinical effect of vitamin D treatment in women with PCOS.
- Trial name
- NCT03644212
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Insulin Sensitizers Role in Control of PCOS Vicious Cycle.
PCOS is a common and complex disease affecting women of reproductive age. It is characterized by its complex pathological symptoms and mechanisms resulting in endocrine and metabolic dysfunction.
- Trial name
- NCT06170463
- Testing
- Metformin Hydrochloride, MI/DCI combination in 40:1 ratio, Combination of Metformin hydrochloride and MI/DCI
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Zagazig University
Hyperandrogenemia, Obesity
Effect of Short Term Adrenal Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess
Short term hydrocortisone to test whether improves excess androgen production from adrenal gland and ovaries
- Conditions
- Hyperandrogenemia, Obesity, Polycystic Ovary Syndrome
- Trial name
- NCT01422707
- Testing
- Hydrocortisone
- Where
- United States
- Sponsor
- University of Virginia
PCOS
The Effect of Polycystic Ovary Syndrome on the Embryo Morphokinetics ( PCOS )
Polycystic ovarian syndrome (PCOS) is a complex endocrine and metabolic syndrome which accounts for 75% of women with anovulatory infertility. The cause of infertility in PCOS is already unknown.
- Trial name
- NCT05438355
- Where
- China
- Volunteers
- 153 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Polycystic Ovary Syndrome
Adipocytokines and Polycystic Ovary Syndrome (PCOS)
Inflammation may play a role in the development of polycystic ovary syndrome (PCOS). In this study, the investigators investigated the expression of different mediators of inflammation in fatty tissue and in blood in women with…
- Trial name
- NCT00975832
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Polycystic Ovary Syndrome, Abnormal Weight Gain
Go Girls! Fitness Support Group Intervention Effectiveness Study
The main purpose of this study is to determine if the Go Girls! program to take place at the Kluge Children's Rehabilitation Center Therapeutic Recreation Gymnasium, intended to introduce girls to a fun, non-threatening…
- Conditions
- Polycystic Ovary Syndrome, Abnormal Weight Gain, Excess Weight, Insulin Resistance
- Trial name
- CBS002 (NCT02117063)
- Testing
- Go Girls! Fitness Support Group
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome
Effect of Dietary Fiber Intervention on Patients With Polycystic Ovary Syndrome
The purpose of the study is to understand the effect of dietary fiber on patients with polycystic ovary syndrome.
- Trial name
- NCT05431816
- Testing
- Dietary intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome, Infertility
Graceful Lifestyle Changes Study for PCOS and Infertility
The purpose of this study is to help women with PCOS to improve their symptoms and ovulation rate through a lifestyle intervention program which introduces a specific diet, a physical activity regimen and mindfulness exercises to…
- Trial name
- GLC (NCT02630485)
- Testing
- Graceful Lifestyle Changes, Myo-inositol, Letrozole
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cardiac Disease
Women With Polycystic Ovary Syndrome Are at High Risk for Cardiac Insults
Objectives: Evaluation of the cardiovascular (CV) risk in a sample of CV asymptomatic infertile women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT05344547
- Testing
- Cardiac risk ratio (CRR)
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Tanta University
Polycystic Ovary Syndrome, Vitamin D Deficiency
30000 IU Per Week Vitamin D Treatment in PCOS Patients
This is a human, II/b phase, multicentre, randomised, double blind, placebo-controlled study to assess the safety and the efficacy of a weekly administered dose of 30,000 IU vitamin D (colecalciferol) in deficient patients…
- Trial name
- NCT04840238
- Testing
- Cholecalciferol
- Where
- 8 sites in Hungary
- Volunteers
- 115 people
- Sponsor
- Semmelweis University
Polycystic Ovary Syndrome
Effect of Meal Composition on Postprandial Testosterone Concentration in Women With Polycystic Ovary Syndrome
The primary objective is to determine if meals of different fat and fiber content affect postprandial plasma testosterone concentration in women with polycystic ovary syndrome.
- Trial name
- NCT00455338
- Testing
- Meal Composition
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Polycystic Ovary Syndrome
Letrozole Versus Chinese Herbal Medicine on Polycystic Ovary Syndrome (PCOS)
This is a multicenter double-blind randomized controlled trial. A total of 420 anovulatory Chinese women with PCOS will be recruited, and the randomization will be stratified by each participating site.
- Trial name
- NCT01431352
- Testing
- Letrozole
- Where
- 18 sites in China
- Volunteers
- 420 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Polycystic Ovary Syndrome, Insulin Resistance
Effects of Intermittent Fasting on Polycystic Ovary Syndrome (PCOS) Compared to Standard Treatment
The purpose of this study is to assess the effects of Time restricted eating in patients diagnosed with polycystic ovary syndrome, comparing it to the standard hormonal treatment.
- Trial name
- NCT06031753
- Testing
- Time restricted eating
- Where
- Mexico
- Volunteers
- 16 people
- Sponsor
- Instituto Superior de Investigación en Estética Médica, Nutrición y Anti-Envejecimiento
Polycystic Ovary Syndrome
Multimodal Ocular Diagnosis-Guided Precision Acupuncture and Lifestyle Intervention for PCOS
This study is designed as a prospective, multicenter, parallel-group randomized controlled trial to evaluate the effectiveness of a "precision acupuncture + personalized lifestyle" intervention, guided by dynamic multimodal risk…
- Trial name
- NCT07809503
- Testing
- Model-Guided Precision Acupuncture, Personalized Lifestyle Intervention, Conventional Acupuncture
- Where
- 2 sites in China
- Volunteers
- 210 people
- Sponsor
- Peking University Third Hospital
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