Clinical trials: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome, Severe Obesity
Effect of Metabolic Surgery on Live Birth Rate of Offspring in Obesity Polycystic Ovarian Syndrome Patients
This is a experimental study, which subjects are obese PCOS patients requiring LSG surgery. Aim to investigate the effects of LSG surgery in PCOS patients whether increases the live birth rate of the offspring.
- Conditions
- Polycystic Ovary Syndrome, Severe Obesity, Laparoscopic Sleeve Gastrectomy
- Trial name
- NCT04151459
- Testing
- Metformin
- Where
- China
- Volunteers
- 18 people
- Sponsor
- RenJi Hospital
Polycystic Ovary Syndrome (PCOS)
A Clinical Trial to Evaluate the Efficacy, Tolerability, and Safety of a Fixed Dose Combination of Spironolactone, Pioglitazone & Metformin (SPIOMET) in Polycystic Ovary Syndrome (PCOS)
This is a multi-centre, multi-national, double-blinded, placebo-controlled, parallel, randomised Phase II clinical trial to evaluate the efficacy, tolerability, and safety of a fixed dose combination of Spironolactone…
- Trial name
- SPIOMET4HEALTH (NCT05394142)
- Testing
- Pioglitazone, Spironolactone, Metformin
- Where
- 7 sites in Austria, Denmark and 4 more
- Volunteers
- 364 people
- Sponsor
- Fundació Sant Joan de Déu
Polycystic Ovary Syndrome
Analysis of Clinical Characteristics and Study of Diagnostic Markers in Patients with Polycystic Ovary Syndrome
The investigators collected clinical data and serum samples of patients with polycystic ovary syndrome in this study, used statistical software such as SPSS for data analysis, and used experimental techniques such as ELISA to…
- Trial name
- NCT05063383
- Testing
- This study does not involve any interventions
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai 10th People's Hospital
Polycystic Ovary Syndrome, Hyperinsulinism
Effects Of Combined Cryolipolysis And High Intensity Interval Training On Insulin Resistance And Body Composition In Polycystic Ovarian Patients
this study will be carried to investigate the effect of cryolipolysis and high intensity interval training on insulin resistance and body composition in pco women
- Trial name
- NCT04744896
- Testing
- cryolipolysis(3 max cool shaping), Treadmill (jkexer focus 8020A)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, T2D
Study on the Efficacy and Safety of Chiglitazar Sodium in PCOS With T2DM
Purpose and significance: To explore the clinical efficacy and safety of Chiglitazar sodium in polycystic ovary syndrome with type 2 diabetes Methods: From October 2022 to September 2024, a total of 142 PCOS with T2DM patients…
- Trial name
- NCT05760677
- Testing
- pioglitazone group: lifestyle intervention+ metformin+ orlistat (obese patients)+ pioglitazone, the Chiglitazar group: lifestyle intervention+ metformin+ orlistat (obese patients)+ Chiglitazar
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Affiliated Hospital of Nantong University
Polycystic Ovary Syndrome, Obesity
Effects of Exercise for Overweight Women With Polycystic Ovary Syndrome
The effects of a 16-week exercise training program on insulin resistance and adiposity in overweight/obese women with Polycystic ovary syndrome (PCOS).
- Trial name
- POLY (NCT01150539)
- Testing
- 16-week exercise training program, Control Group without PCOS
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Pennington Biomedical Research Center
Polycystic Ovary Syndrome
Efficacy of Mazdutide for Treating PCOS
The goal of this clinical trial is to learn the efficacy of Mazdutide in treating obese female adults diagnosed with polycystic ovary syndrome (PCOS).
- Trial name
- NCT06519656
- Testing
- Mazdutide
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Shanghai Zhongshan Hospital
Pregnancy, Polycystic Ovary Syndrome
Pregnancy in Polycystic Ovary Syndrome II
The primary research hypothesis is that ovulation induction with an aromatase inhibitor (letrozole) is more likely to result in live birth than ovulation induction with a selective estrogen receptor modulator (clomiphene citrate)…
- Trial name
- PPCOSII (NCT00719186)
- Testing
- Clomiphene citrate, Letrozole
- Where
- 12 sites in United States
- Volunteers
- 750 people
- Sponsor
- Yale University
Quality of Life
Anxiety and Sexual Malfunction Functions in Infertile Pcos Women
Polycystic ovary syndrome (PCOS) is a common hormonal disorder in females in reproductive age associated with signs and symptoms as amenorrhea or oligomenorrhea, obesity,infertility acne and hirsutism tism that mostly Reduce self…
- Trial name
- NCT05056272
- Where
- Egypt
- Volunteers
- 129 people
- Sponsor
- Assiut University
PCOS, Insulin Resistance
Myoinositol Treatment and Asprosin Levels in PCOS
Policystic ovary syndrome is the most common endocrinopthy during reproductive period. One of the factors implicated in the pathogenesis is insulin resistance.
- Trial name
- NCT05951309
- Testing
- inofolic combi, Glucophage 500Mg Tablet
- Where
- Cyprus
- Volunteers
- 30 people
- Sponsor
- Near East University, Turkey
Obesity
Clinical Efficacy and Safety of a Laparoscopic Sleeve Gastrectomy in Obese Patients
This study aim to evaluate the clinical efficacy and safety after laparoscopic sleeve gastrectomy in patients with obesity. 300 patients with obesity and 49 healthy individuals with normal BMI were enrolled.
- Trial name
- NCT04548232
- Testing
- Laparoscopic sleeve gastrectomy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Insulin Sensitizers Role in Control of PCOS Vicious Cycle.
PCOS is a common and complex disease affecting women of reproductive age. It is characterized by its complex pathological symptoms and mechanisms resulting in endocrine and metabolic dysfunction.
- Trial name
- NCT06170463
- Testing
- Metformin Hydrochloride, MI/DCI combination in 40:1 ratio, Combination of Metformin hydrochloride and MI/DCI
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Zagazig University
Polycystic Ovary Syndrome
Sebum Measurement in Newborn to Detect Hyperexposure to Androgens
The source of PCOS is unknown. Our hypothesis is that over exposure to testosterone of the foetus in utero alters the expression of genes thought to be involved in the cause of PCOS.
- Trial name
- NCT04065100
- Testing
- Sebum test
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Homerton University Hospital NHS Foundation Trust
Reproductive Disorder, PCOS
Dampening the Reproductive Axis With Continuous Kisspeptin
The goal of this study is to assess response to kisspeptin as well as the baseline patterns of luteinizing hormone (LH) secretion in individuals with polycystic ovarian syndrome (PCOS).
- Conditions
- Reproductive Disorder, PCOS, Polycystic Ovary Syndrome
- Trial name
- NCT05971849
- Testing
- kisspeptin 112-121
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Stephanie B. Seminara, MD
Polycystic Ovary Syndrome, Overweight and Obesity
Lifestyle Intervention in Pregnant Women With PCOS
Polycystic ovarian syndrome (PCOS) is the most common reproductive disorder in women of childbearing age and is also associated with metabolic abnormalities including obesity, type 2 diabetes, dyslipidemia, etc.
- Conditions
- Polycystic Ovary Syndrome, Overweight and Obesity, Gestational Diabetes
- Trial name
- NCT04216485
- Testing
- Intensive Lifestyle Intervention, Standard Care
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Capital Medical University
Polycystic Ovary Syndrome (PCOS), Female Endocrine Disorder
A Study of AZD4901 in Females With Polycystic Ovary Syndrome
To assess the effects of AZD4901 when given in multiple doses to females with Polycystic Ovary Syndrome
- Trial name
- NCT01872078
- Testing
- AZD4901 (oral)
- Where
- 7 sites in United States, Germany and 1 more
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Polycystic Ovary Syndrome
Metformin in Infertile PCOS Patients
Metformin, an oral biguanide administrated for treating type-2 diabetes mellitus, is a safe and effective drug recently experimented also in patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT00501904
- Testing
- Metformin
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University Magna Graecia
PCOS, Myo-inositol-resistance
Myo-inositol Plus Alpha-lactalbumin in PCOS Myo-inositol-resistant Patients
The investigator's aim is to evaluate if the combination of myo-inositol and alpha-lactalbumin can overcome the resistance to myo-inositol in PCOS patients
- Trial name
- NCT03667443
- Testing
- Myo-inositol + folic a. + α-lactalbumin, Myo-inositol + folic a.
- Where
- Bulgaria
- Volunteers
- 50 people
- Sponsor
- Lo.Li.Pharma s.r.l
Polycystic Ovary
Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome
The aim of the study is to assess the efficacy of adjuvant therapy dapagliflozin, metformin as monotherapy and combination of both in comparison to control group in induction of ovulation with letrozole in women PCOS, focusing…
- Trial name
- NCT06405178
- Testing
- Metformin, Dapagliflozin, Dapagliflozin/Metformin
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
Polycystic Ovary Syndrome, Infertility
New Application of Sequential in Vitro Muturation System for Infertility Patients With Polycystic Ovary Syndrome
Oocyte in vitro maturation (IVM) is an artificial reproductive technologies (ART) in which cumulus-oocyte complex (COC) are collected at the immature germinal vesicle (GV) stage from unstimulated or FSH-primed ovaries and matured…
- Trial name
- NCT03773263
- Testing
- sequential IVM system, intracytoplasmic sperm injection (ICSI), Thawed embryo transfer (TET)
- Where
- 5 sites in China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-sen University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.