Clinical trials: Polycystic Ovary Syndrome
Metabolic Syndrome, Polycystic Ovary Syndrome
Evaluation of Licorice Root on Metabolic Syndrome in Polycystic Ovary Syndrome Females
The goal of this study is to learn about the effect of licorice root powder on parameters of metabolic syndrome in those women diagnosed with PCOS with age range of 15-49 years of age.
- Trial name
- NCT06043375
- Testing
- Licorice Root Powder Capsule
- Where
- Pakistan
- Volunteers
- 55 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Polycystic Ovary Syndrome
High Versus Normal Protein Diet in Polycystic Ovary Syndrome (PCOS)
The objective of this study is to assess the effects of a high protein (HP) and a normal protein diet (NP) on patients with polycystic ovary syndrome (PCOS) and body mass index (BMI)-matched controls in a sample of southern…
- Trial name
- NCT01184963
- Testing
- High protein diet, Normal protein diet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Polycystic Ovary Syndrome (PCOS)
The Value of LC-MS/MS Detection of Androgen Profiles in the Diagnosis of PCOS: A Prospective, Multicenter Real-world Study
Introduction : Androgens play a vital role in the female reproductive system, influencing ovarian follicular development, oocyte quality, and ovarian responsiveness to controlled ovarian stimulation.
- Trial name
- NCT07916909
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Polycystic Ovary Syndrome
Inositol Treatment in Different Type of PCOS Phenotype
Evaluation of the efficacy of inositol treatment in women with PCOS in relation to the phenotype (according to the Rotterdam Criteria)
- Trial name
- NCT05678114
- Testing
- Myo-inositol
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Lo.Li.Pharma s.r.l
Hepassocin (Hepatocyte-derived Fibrinogen-related Protein 1), Polycystic Ovary Syndrome
Hepassocin Levels in Patients With Polycystic Ovary Syndrome
The investigators aimed to investigate hepassocin levels in patients with polycystic ovary syndrome (PCOS). There are 3 groups aged between 18 and 35 years as non-obese healthy women, non-obese women with PCOS, and obese women…
- Conditions
- Hepassocin (Hepatocyte-derived Fibrinogen-related Protein 1), Polycystic Ovary Syndrome, Obesity, Insulin Resistance
- Trial name
- NCT04369248
- Testing
- hepassocin
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fatma ketenci gencer
Polycystic Ovary Syndrome
Metformin Suspension and Insulin Sensitivity
Metformin is an insulin sensitizing drug routinely used for the treatment of anovulatory patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT00437333
- Testing
- Metformin cloridrate
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University Magna Graecia
Infertility, Female, Polycystic Ovary Syndrome
Antioxidant Supplement Associated With Oral Probiotics in Patients With PCOS in IVF
The aim of the study is to study the effect of an antioxidant food supplement associated with probiotics on the oocyte quality response, oxidative stress and microbiota function in an in vitro fertilization cycle in patients with…
- Trial name
- NCT04670393
- Testing
- FertyBiotic Woman Plus
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fertypharm
PCOS (Polycystic Ovary Syndrome)
The Aim of This Study is to Gain Insight Into the Occurrence of Irritable Bowel Symptoms During Ovarian Stimulation in Individuals With PCOS and in Women Who Wish to Freeze Their Eggs. This Study Uses Questionnaires.
This exploratory study investigates the impact of fertility treatments on symptoms of irritable bowel syndrome (IBS) in women. Specifically, the study focuses on two groups: Women with polycystic ovary syndrome (PCOS) who are…
- Trial name
- FIBS (NCT07533968)
- Testing
- questionnaires
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Polycystic Ovary Syndrome
Theca Cell Function in Women With Polycystic Ovary Syndrome (PCOS)
The mechanism for increased androgen production in women with polycystic ovary syndrome (PCOS) is not well understood. Excess androgen production by the ovary is stimulated by increased pituitary luteinizing hormone (LH)…
- Trial name
- NCT00747617
- Testing
- recombinant human chorionic gonadotropin
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Polycystic Ovary Syndrome, Hypothalamic-Pituitary-Ovarian Axis Dysfunction (Disorder)
Subclinical Hypothyroidism and Normogonadotropic Anovulation
Thyroid hormones (TH) can modify the functioning of the hypothalamic-pituitary-ovarian axis, affecting the functions of granulosa cells and the development and apoptosis of preantral follicles.
- Trial name
- NCT05782725
- Testing
- Comparison of laboratory test results in women in the 4 study arms
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Jagiellonian University
Infertility
HRT Versus MOS for Endometrial Preparation Prior to FET in Non PCOS Patients
Evaluation of endometrial preparation using either hormonal therapy or ovarian stimulation prior to frozen-thawed embryo transfer (FET) in patients without polycystic ovarian syndrome (PCOS)
- Trial name
- NCT02330757
- Testing
- Estradiol valerate, Sequential Clomiphene citrate and Gonadotropin
- Where
- 2 sites in Egypt
- Volunteers
- 150 people
- Sponsor
- Mansoura University
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Dysglycemia
Glucose Evaluation Through Continuous Glucose Monitors in Polycystic Ovary Syndrome
PCOS is the most common endocrine disorder of reproductive aged women. In addition to menstrual and endocrine abnormalities, PCOS is characterized by insulin resistance and glycemic dysregulation.
- Conditions
- PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Dysglycemia, Insulin Resistance
- Trial name
- GEMS-PCOS (NCT06050265)
- Testing
- DEXCOM Continuous Glucose Monitor (CGM)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Polycystic Ovary Syndrome (PCOS)
Fertility and Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and affects approximately 10% of women worldwide.
- Trial name
- FERTIOPK (NCT07499518)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 473 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Polycystic Ovary Syndrome
Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
Polycystic ovary syndrome (PCOS) is a common endocrinopathy affecting 6.5%-6.7% of women in reproductive age, and is commonly associated with obesity, menstrual irregularity, insulin resistance (IR), infertility, and clinical…
- Trial name
- NCT01021579
- Testing
- Metfomin plus Simvastatin
- Where
- Iran
- Volunteers
- 84 people
- Sponsor
- Fasa University of Medical Sciences
Polycystic Ovary Syndrome
Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS
Polycystic ovary syndrome (PCOS) is the most common reproductive disorder in women of reproductive age and despite decades of research the etiology the disorder is not known.
- Trial name
- PULSE (NCT01482286)
- Testing
- Metformin, Dietary Restriction, Exercise Training
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Pennington Biomedical Research Center
Polycystic Ovarian Syndrome (PCOS)
Treatment of Women With Hyperandrogenic PCOS With Two Different Ratios of Myo-inositol:D-chiro-inositol: A Comparison
In this study, female patients diagnosed with polycystic ovary syndrome (PCOS) will be enrolled. In particular, those with elevated testosterone or with clinical signs of hyperandrogenism, along with menstrual cycle alterations…
- Trial name
- NCT06715527
- Testing
- Myo-Inositol and D-Chiro-Inositol (40:1), Myo-Inositol and D-Chiro-Inositol (3.6:1)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Lo.Li.Pharma s.r.l
PCOS (Polycystic Ovary Syndrome)
The Effects of the Mediterranean Diet and Synbiotics in Polycystic Ovary Syndrome
This study will look at whether a reduced-calorie Mediterranean-style eating plan, together with a synbiotic supplement, can improve health measures and quality of life in women who have polycystic ovary syndrome (PCOS) and are…
- Trial name
- NCT07342946
- Testing
- Synbiotic Supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Atlas University
Polycystic Ovary Syndrome
Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.
This study aimed to understand whether metformin therapy can improve insulin resistance in adolescent PCOS patients, both during treatment and after discontinuation, and to evaluate its action on the hormonal and metabolic…
- Trial name
- NCT06015594
- Testing
- Metformin
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Polycystic Ovary Syndrome, Infertility
Therapy for Infertile PCOS Patients Ovulating Under Clomiphene Citrate or Metformin
Several data demonstrated that both clomiphene citrate (CC) and metformin are two safe and valid first-step options to induce ovulation in infertile anovulatory PCOS patients.
- Trial name
- NCT00502229
- Testing
- Clomiphene citrate, metformin, highly purified urinary FSH
- Where
- Italy
- Sponsor
- University Magna Graecia
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Letrozole Alone Protocol Versus Using Letrozole and HCG Protocol
Letrozole is a chemical compound, CGS 20267 which is a third-generation, nonsteroidal aromatase inhibitor. Letrozole blocks estrogen synthesis by directly affecting the hypothalamic-pituitary-ovarian axis, subsequently, increases…
- Trial name
- NCT06367712
- Testing
- Letrozole tablets
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Egymedicalpedia
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