Clinical trials: Polycystic Ovary Syndrome
Polycystic Ovarian Syndrome
Flaxseed Lignan (Brevail)
PCOS is a disorder which is characterized by hyperandrogenism (high serum male hormone levels), ovulatory dysfunction, and polycystic ovaries (multiple follicles-over 12- in the ovary).
- Trial name
- NCT01396369
- Testing
- Birth control, Birth control plus Brevail
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Kansas Medical Center
PCOS (Polycystic Ovary Syndrome), Stone, Urinary
Polycystic Ovary Syndrome and Urinary Tract Stones: a BMI-Adjusted Analysis in Iraqi Women
The goal of this observational case-control study is to find out the impact of PCOS as a risk factor for the presence of urinary tract stones taking into account the BMI of women aged 18-40 years consulting the gynecology and…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Stone, Urinary, BMI, Obesity
- Trial name
- NCT06729359
- Testing
- Ultrasonography of the abdomen and pelvis
- Where
- Iraq
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- Al-Kindy College of Medicine
Obesity, Hyperandrogenemia
Effect of Spironolactone on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess
Whether 12 weeks of spironolactone can reduce androgen production from ovaries and adrenal glands of girls with obesity and androgen excess
- Conditions
- Obesity, Hyperandrogenemia, Polycystic Ovary Syndrome
- Trial name
- NCT01422759
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Laparoscopic, Ovarian Drilling
Unilateral vs Bilateral Laparoscopic Ovarian Drilling In Clomiphene Citrate Resistant Cases of Polycystic Ovarian Syndrome
The aim of the current study is to compare the efficacy of laparoscopic unilateral ovarian drilling with bilateral ovarian drilling in clomiphene citrate resistant cases of polycystic ovarian syndrome in terms of clinical…
- Conditions
- Laparoscopic, Ovarian Drilling, Clomiphene Citrate, Polycystic Ovarian Syndrome
- Trial name
- NCT06537102
- Testing
- Unilateral laparoscopic ovarian drilling, Bilateral laparoscopic ovarian drilling
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Tanta University
Polycystic Ovary Syndrome
Insulin Resistance, Polycystic Ovary Syndrome, and Bone Research Study
The purpose is to investigate the effects of 2 different treatments (drospirenone/ethinyl estradiol versus rosiglitazone) on insulin sensitivity and androgen levels, inflammatory markers, vascular markers and bone development in…
- Trial name
- NCT00640224
- Testing
- rosiglitazone, drospirenone/ethinyl estradiol
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Silva Arslanian
Polycystic Ovary Syndrome
Living With Polycystic Ovary Syndrome
This project aims to develop and pilot an evidence-based structured education program that can be run in groups to enable women with PCOS to make lifestyle changes, which will help them improve their PCOS and reduce the risk of…
- Trial name
- LW-PCOS (NCT04777461)
- Testing
- Survey on patient's perspectives on the development of an structured education programme for PCOS, Pre-pilot questionnaire, Piloting the structured education programme for PCOS
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Hull
PCOS- Polycystic Ovary Syndrome
Translation and Validation of MPCOSQ in Urdu Language
To translate and validate modifies polycystic ovary syndrome quality of life (MPCOQ) questionnaire into Urdu. To evaluate the reliability, validity and of Urdu version of modified polycystic ovary syndrome quality of life…
- Trial name
- NCT05010551
- Where
- 2 sites in Pakistan
- Volunteers
- 180 people
- Sponsor
- Riphah International University
Infertility, Ovulation Induction
SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women
Efficacy and safety studies in the past have suggested that a starting dose of 75 International Unit (IU) of SJ-0021, and an increase in the dose by 37.5 IU every 7 days, are safe for treatment of subjects with ovulatory…
- Trial name
- NCT01185782
- Testing
- Gonalef® (Follitropin alfa), Purified pituitary gonadotropin (Fertinorm-P®)
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Polycystic Ovary Syndrome
Effects of Melatonin in PCOS Women
The aim of our study is to investigate the effects of a treatment with melatonin on clinical, endocrine and metabolic features in women affected by PCOS.
- Trial name
- NCT02663570
- Testing
- Melatonin
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Catholic University of the Sacred Heart
Polycystic Ovary Syndrome
Effect of Ultrasound Acupoints on Patients With Polycystic Ovary Syndrome
This study will be conducted to evaluate the effect of ultrasound acupoints on menstrual irregularity and hormone levels on polycystic ovary syndrome (PCOS) patient.
- Trial name
- NCT06844903
- Testing
- Pulsed ultrasound at acupuncture points, Standard care program
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Kafrelsheikh University
Polycystic Ovary Syndrome
n-3 Polyunsaturated Fatty Acids (PUFA) Supplementation in Young Women With Polycystic Ovary Syndrome (PCOS)
This is a dietary intervention study designed to assess the impact of long chain (LC) n-3 polyunsaturated fatty acids (PUFA) in young women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT01189669
- Testing
- LC n-3 PUFA (fish oil) Supplement
- Where
- 2 sites in Ireland
- Volunteers
- 25 people
- Sponsor
- The Adelaide and Meath Hospital
Polycystic Ovary Syndrome
L-Carnitine and Clomiphene Citrate for Induction of Ovulation in Women With Polycystic Ovary Syndrome
The purpose of the study to assess the efficacy of adding L-carnitine to clomiphene citrate for increasing the ovulation and the pregnancy rate in women with PCOS.
- Trial name
- NCT03476356
- Testing
- oral clomiphene citrate, oral carnitine supplementation
- Where
- Egypt
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome
Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients
The purpose of this study was to determine whether metformin combined with exenatide once weekly (EQW) is more effective than metformin alone in the treatment of overweight/obese women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT04029272
- Testing
- Metformin, Exenatide 2 MG
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking Union Medical College Hospital
Polycystic Ovary Syndrome, Resistance, Insulin
Effects of Myo-inositol in Women With Polycystic Ovary Syndrome
The study will be carried out at the hospital of the medical school of sao paulo (HC-FMUSP) and the goal is to compare the effects of the administration of myo-inositol in relation to the effects of metformin in women with…
- Conditions
- Polycystic Ovary Syndrome, Resistance, Insulin, Glucose Intolerance
- Trial name
- NCT04892186
- Testing
- Myo-inositol, Metformin
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Polycystic Ovary Syndrome, PCOS
Insulin Differences Between African-American and Caucasian Female Adolescents With Polycystic Ovary Syndrome (PCOS)
The purpose of this research study is to see if there are differences between African-American and Caucasian girls with Polycystic Ovary Syndrome (PCOS) in how their bodies respond to a type of sugar, called glucose, the body's…
- Trial name
- NCT02052479
- Testing
- Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nationwide Children's Hospital
Polycystic Ovary Syndrome
Reproductive Endocrinology Oxford Study (RepOx)
This is a prospective observational study that aims to identify the underlying mechanisms of PolyCystic Ovarian Syndrome (PCOS) and associated comorbidities such as subfertility, miscarriage; and pregnancy complications such as…
- Trial name
- RepOx (NCT05177562)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 1,175 people
- Sponsor
- University of Oxford
Polycystic Ovary Syndrome
Effect of Increased Circulating Androgens on Granulosa Cell Responses to FSH.
The purpose of this study is to evaluate the effect of increased circulating androgens on estradiol production by the granulosa cells in response to FSH stimulus.
- Trial name
- NCT02389088
- Testing
- Letrozole
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Polycystic Ovary Syndrome, Insulin Resistance
Acupuncture or Metformin for Insulin Resistance in Women With PCOS
The hypothesis is that acupuncture is equally effective as metformin (both treatments combined with lifestyle management) in improving whole body glucose homeostasis in insulin resistant women with polycystic ovary syndrome…
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Hyperandrogenism
- Trial name
- PIAII (NCT02647827)
- Testing
- Lifestyle management, Acupuncture, Metformin
- Where
- 2 sites in China, Sweden
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Poly Cystic Ovary Syndrome
Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients
This study evaluates the efficacy of alpha-lipoic acid combined with myo-inositol, with or without metformin, in improving menstrual regularity and ovulation in non-diabetic women with polycystic ovary syndrome (PCOS).
- Trial name
- ALA-MYO-PCOS (NCT07630779)
- Testing
- Myo-inositol, Folic Acid, Alpha Lipoic Acid
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Beni-Suef University
Amenorrhea, Oligomenorrhea
Treatment of Menstrual Cycle Alterations in Adolescents
the aim of the present study is intended to evaluate how treatment with Myo-Inositol and Dioscorea Villosa can help improve menstrual cycle irregularities in adolescents, both with and without PCOS.
- Conditions
- Amenorrhea, Oligomenorrhea, PCOS (Polycystic Ovary Syndrome)
- Trial name
- HP-phD_Adolesc (NCT06800170)
- Testing
- myo-Inositol plus DIoscorea Villosa
- Where
- 2 sites in Georgia, Russia
- Volunteers
- 41 people
- Sponsor
- Lo.Li.Pharma s.r.l
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