Clinical trials: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
Study of Metabolism and Cardiovascular Disease(CVD) in Women With Polycystic Ovary Syndrome (PCOS)
PCOS is the most common endocrine disorder in reproductive women. It is estimated that 5 to 10% of women of reproductive age have PCOS.
- Trial name
- NCT01117558
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Polycystic Ovarian Syndrome (PCOS), Pittsburg Sleep Quality Index
Diaphragmatic Breathing Exercises on Sleep Disorders un Polycystic Ovarian Syndrome
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in females in reproductive age and not completely understood. Women with PCOS appear to have an increased frequency of sleep problems.
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Pittsburg Sleep Quality Index, Fatigue Severity Scale, Insomnia Severity Index
- Trial name
- NCT07698925
- Testing
- Diaphragmatic breathing exercises, Lifestyle modification advices
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Adly A Adam
Polycystic Ovary Syndrome
Metformin in Assisted Reproduction-MET-AR-study
Aim of study: To investigate whether four months of metformin treatment before IVF (in-vitro-fertilisation) or ICSI (intra-cytoplasmic-sperm-injection) might increase clinical pregnancy rate in normal-weight (body mass index…
- Trial name
- NCT00159575
- Where
- 2 sites in Norway
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Polycystic Ovary Syndrome
Berberine Phytosome for Signs and Symptoms of Polycystic Ovary Syndrome (PCOS)
This multicenter, randomized, controlled clinical trial aims to evaluate the effectiveness of berberine phytosome supplementation in improving signs and symptoms associated with polycystic ovary syndrome (PCOS).
- Trial name
- NCT07465575
- Testing
- Berberine Phytosome (Sophy®), Lifestyle Advice
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Cardiovascular Diseases
Reexamining Her Cardiovascular Risk - Ottawa WomeN's Longitudinal Cohort Study
The full HER CROWN will be a prospective cohort study to propose a novel, women-specific cardiovascular risk score/ algorithm in the prediction of hard cardiovascular outcomes (myocardial infarction, unstable angina, coronary…
- Trial name
- HER-CROWN (NCT05632601)
- Testing
- PET scan
- Where
- Canada
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
PCOS, Polycystic Ovary Syndrome
Clinical, Metabolic and Endocrine Effects of the Treatment With Drospirenone and Ethinyl Estradiol Alone or in Combination With Myo-inositol in Young Women With Polycystic Ovary Syndrome (PCOS) and Insulin Resistance
Polycystic ovary syndrome (PCOS) is a heterogeneous syndrome with a variety of metabolic and endocrine abnormalities and clinical symptoms.
- Trial name
- NCT01511822
- Testing
- Drospirenone Ethinyl estradiol, Drospirenone Ethinyl estradiol Myo-inositol
- Where
- Italy
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Polycystic Ovarian Syndrome
Sitagliptin or BeiDouGen Capsule Improve the Pregnancy Outcome in Patients with PCOS
This study will be carried out under the guidance of professional doctor, patients with PCOS will be treated with Sitagliptin or BeiDouGen capsule or both two to assess their ovarian function and reproductive outcomes, and…
- Trial name
- NCT06587698
- Testing
- Sitagliptin, BeiDouGen, Sitagliptin+BeiDouGen
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome, Infertility, Female
Effect of ALA Combined With Letrozole on Polycystic Ovary Syndrome Clinical Outcome in Infertile Females
This research study aims to investigate the effect of adding Alpha lipoic acid (ALA) supplement to letrozole treatment in infertile women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT06418347
- Testing
- Alpha lipoic acid, Letrozole
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome
PCOS Indirect and Intangible Economic Burden
The primary purpose of the PCOS Indirect and Intangible Economic Buren study is to estimate the economic costs of having PCOS in terms of quality of life and work productivity.
- Trial name
- PCOSCHALLENGE (NCT05903404)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- PCOS Challenge: The National Polycystic Ovary Syndrome Association
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Subclinical Hypothyroidism
Best Treatment for Women With Both (Polycystic Ovary Syndrome) PCOS and Subclinical Hypothyroidism
The goal of this randomized controlled trial is to compare letrozole alone versus letrozole plus levothyroxine for ovulation induction in infertile women with both PCOS and subclinical hypothyroidism.
- Conditions
- PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Subclinical Hypothyroidism, Female Infertility
- Trial name
- NCT06041204
- Testing
- Letrozole 2.5mg, Levothyroxine 25 Mcg (0.025 Mg) Oral Tablet
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy
Polycystic Ovary Syndrome
Research of Intensive Lifestyle Intervention for PCOS Patients With IGT
Compare the efficacy between intensive lifestyle intervention and drugs (GLP-1 Receptor Agonists, metformin and acarbose) for PCOS patients with early onset diabetes in their metabolic and reproductive abnormalities treatment…
- Trial name
- NCT02446834
- Testing
- intensive lifestyle intervention, GLP-1 Receptor Agonists, Metformin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Poly Cystic Ovary Syndrome
Evaluation of the Effects of Diosmin/Hespiridin Combination on the Clinical Outcomes in Patients With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is one of the most prevalent disorders worldwide. Insulin resistance, inflammation and disturbance in sex hormone levels are the main contributing factors of this disease.The majority of studies…
- Trial name
- NCT06083935
- Testing
- Daflon, Combined oral contraceptive, Metformin
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome, Obesity
Time Restricted Eating for the Treatment of PCOS
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility among young women. This syndrome is a reproductive and endocrinological disorder that affects up to 18% of reproductive-aged women.
- Conditions
- Polycystic Ovary Syndrome, Obesity, Overweight
- Trial name
- NCT05629858
- Testing
- 6-h Time restricted eating (TRE), Calorie restriction (CR), Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Polycystic Ovary Syndrome
Multi-omics Analysis of Women With PCOS and Obesity Compared With Non-PCOS Obese Controls
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in reproductive-aged women， which associated with increased risks to develop metabolic disorders, including cardiovascular diseases, diabetes mellitus…
- Trial name
- NCT05468476
- Testing
- No intervention
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Zhang Manna
Infertility, Obesity
Metabolomic Embryo Profiles of Obese in Vitro Fertilization (IVF) Patients and Their Relationship With Polycystic Ovary Syndrome (PCO)
The present study aims to elucidate if there is a metabolomic profile alteration in the embryos of obese women in order to understand if the reduced implantation rate observed in these patients is directly related to this factor.
- Trial name
- NCT01448863
- Testing
- Culture medium metabolomic analysis
- Where
- 2 sites in Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Polycystic Ovary Syndrome
Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy
Oral contraceptives are known to improve menstrual cycles and symptoms in PCOS, however may increase cholesterol. Metformin, a drug to improve insulin resistance, may benefit metabolic state.
- Trial name
- NCT00283816
- Testing
- Metformin, Oral Contraceptive Pill, Lifestyle Management Program
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Infertility
Letrozole Versus Laparoscopic Ovarian Drilling in Polycystic Ovary Syndrome
Polycystic ovary syndrome is the major cause of anovulatory infertility. Clomiphene citrate is the most commonly used oral agent for ovulation induction in this group, but there are some drawbacks with the use of it.
- Trial name
- NCT03009838
- Testing
- Letrozole, ovarian drilling
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Infertility, Polycystic Ovarian Syndrome
Ovarian Stimulation and Intrauterine Insemination in Women With Polycystic Ovarian Syndrome
The study null hypothethesis is: intrauterine insemination (IUI) does not improve pregnancy rates in women with polycystic ovary syndrome.
- Conditions
- Infertility, Polycystic Ovarian Syndrome, Intrauterine Insemination
- Trial name
- OSIPS (NCT01675843)
- Testing
- Intrauterine insemination (IUI)
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Mansoura University
PCO - Polycystic Ovaries, Obesity and Obesity-related Medical Conditions
The Effectiveness of Astaxanthin Supplementation on the Clinical Symptoms and Cardio-metabolic Profile in Women with Polycystic Ovary Syndrome
Abstract Background: This trial aims to investigate the effect of 12 weeks of 10 mg/day astaxanthin (ASX) administration compared with the control group on insulin sensitivity, lipid profile, circulating MDA levels, severity of…
- Trial name
- NCT06642363
- Testing
- Subjects in the intervention group will receive one capsule containing 10 mg Astaper day made by the "Zyest Technology Tarawat Zendig" institute in Iran. The dosage of ASX is determined based on the s
- Where
- Iran
- Volunteers
- 44 people
- Sponsor
- Isfahan University of Medical Sciences
Polycystic Ovary Syndrome (PCOS)
Phenotyping of Patients With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the leading endocrine disorder of the reproductive system, affecting 10 to 13% of women of childbearing age.
- Trial name
- SOPK (NCT07339930)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
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