Clinical trials: Polycystic Ovary Syndrome
Women Health, Polycystic Ovary Syndrome (PCOS)
Mobile Application for Women With Polycystic Ovary Syndrome
Objective: The aim is to develop a mobile application based on the Health Promotion Model for the management of PCOS and to determine the effect of this application on improving nutrition and exercise behavior in women with PCOS.
- Conditions
- Women Health, Polycystic Ovary Syndrome (PCOS), Physiotherapy and Rehabilitation, Dietetics
- Trial name
- Polycystic (NCT07371364)
- Testing
- Mobile application, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Istanbul Medipol University Hospital
Polycystic Ovary Syndrome
Multimodal Ocular Diagnosis-Guided Precision Acupuncture and Lifestyle Intervention for PCOS
This study is designed as a prospective, multicenter, parallel-group randomized controlled trial to evaluate the effectiveness of a "precision acupuncture + personalized lifestyle" intervention, guided by dynamic multimodal risk…
- Trial name
- NCT07809503
- Testing
- Model-Guided Precision Acupuncture, Personalized Lifestyle Intervention, Conventional Acupuncture
- Where
- 2 sites in China
- Volunteers
- 210 people
- Sponsor
- Peking University Third Hospital
Cardiovascular Diseases
Reexamining Her Cardiovascular Risk - Ottawa WomeN's Longitudinal Cohort Study
The full HER CROWN will be a prospective cohort study to propose a novel, women-specific cardiovascular risk score/ algorithm in the prediction of hard cardiovascular outcomes (myocardial infarction, unstable angina, coronary…
- Trial name
- HER-CROWN (NCT05632601)
- Testing
- PET scan
- Where
- Canada
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Polycystic Ovary Syndrome, Infertility, Female
The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System
A Prospective, Multicenter, Randomized, Pivotal Study of the May Health System in Transvaginal Ablation of Ovarian Tissue under Ultrasound Guidance in Women with Infertility due to Polycystic Ovary Syndrome
- Trial name
- NCT06206746
- Testing
- May Health System
- Where
- 19 sites in United States
- Volunteers
- 93 people
- Sponsor
- May Health
Polycystic Ovary Syndrome
Acupuncture for Insulin Resistance in Women With Polycystic Ovary Syndrome
This two-stage clinical research programme aims to evaluate the preliminary effectiveness and safety of acupuncture for improving insulin resistance in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT07806656
- Testing
- Active Acupuncture, Lifestyle Management
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Peking University Third Hospital
Type 1 Diabetes Mellitus, Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome in Type 1 Diabetes
BACKGROUND Functional ovarian hyperandrogenism, including the polycystic ovary syndrome (PCOS), is very prevalent in women with type 1 diabetes (T1D). The pathogenic mechanisms of this association remain unclear.
- Trial name
- NCT07490964
- Testing
- Type 1 diabetes mellitus, Elevated circulating androgen levels, Sex dimorphism
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Polycystic Ovary Syndrome
Effect of Sitagliptin on Polycystic Ovarian Syndrome Patients
The Study aims to determine the proposed positive influence of Sitagliptin in manipulating hormonal , metabolic and inflammatory parameters in the treatment of Polycystic ovary syndrome and subsequent infertility
- Trial name
- NCT05972928
- Testing
- Sitagliptin 100mg
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Obese
Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome
Girls and women 12-35 years old with obesity and polycystic ovarian syndrome who are on or off metformin, will receive a glucagon like peptide-1 receptor agonist intervention for 10 months to induce metabolic changes, weight loss…
- Trial name
- RESTORE (NCT05819853)
- Testing
- Semaglutide Injectable Product (Wegovy and/or Ozempic)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Colorado, Denver
Polycystic Ovary Syndrome (PCOS) Women
Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS
This double-blind, placebo-controlled, parallel-group randomized controlled trial evaluated changes in metabolic, vitamin B12, iron-status, erythropoietic, and hematological parameters among women with polycystic ovary syndrome…
- Trial name
- MET-PCOS (NCT07793838)
- Testing
- Metformin
- Where
- Jordan
- Volunteers
- 400 people
- Sponsor
- Jerash Private University
Polycystic Ovary
The Supporting Understanding of PCOS Education and Research (SUPER) Study
This research will test whether a Dietary Approaches to Stop Hypertension (DASH) or a very low-carbohydrate diet better improves outcomes like blood glucose control and body weight for adults with polycystic ovary syndrome.
- Trial name
- SUPER (NCT05452642)
- Testing
- DASH diet, Very low-carbohydrate diet
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- University of Michigan
Polycystic Ovary
Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome
The aim of this study is to compare the hormonal, metabolic and clinical effects of metformin and liraglutide in infertile women with PCOs.
- Trial name
- NCT05965908
- Testing
- liraglutide, Metformin
- Where
- Egypt
- Volunteers
- 183 people
- Sponsor
- Beni-Suef University
PCOS
PCOS and Brain Health
The purpose of this study is to determine how polycystic ovary syndrome (PCOS) impacts overall brain health, such as cerebral blood flow (CBF), brain structure and connectivity, and cognitive performance.
- Trial name
- NCT07727512
- Testing
- MRI Visit, Laboratory Visit
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Polycystic Ovary Syndrome
Myo-Inositol for Ovarian Stimulation and ICSI Outcomes in Women With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder that may affect ovarian function, insulin sensitivity, and fertility.
- Trial name
- NCT07779850
- Testing
- Myo-Inositol, Folic Acid
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Kafrelsheikh University
PCOS (Polycystic Ovary Syndrome), Obese Adolescents
Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)
This pilot randomized controlled study will plan to enroll 36 adolescent females with Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS) to evaluate the effectiveness and feasibility of a tailored…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Obese Adolescents, Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities, Overweight Adolescents
- Trial name
- Beef+ (NCT07780188)
- Testing
- Beef+
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Texas A&M University
Polycystic Ovary Syndrome (PCOS)
Intra-Ovarian PRP Compared With Gonadotropin for Ovarian Response in Letrozole-Resistant PCOS
The goal of this randomized clinical trial is to compare autologous platelet-rich plasma (PRP) with gonadotropin for improving ovarian response in women with letrozole-resistant polycystic ovary syndrome (PCOS).
- Trial name
- NCT07777640
- Testing
- Autologous Platelet-Rich Plasma (PRP), Gonadotropin
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- Bangladesh Medical University
Polycystic Ovary Syndrome
Evaluation of the Venous Thrombotic Biological Profile of Different PCOS Phenotypes: French Cross-sectional Study
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of women of childbearing age. PCOS can be individualized into several phenotypes, taking into account in particular the presence of hyperandrogenism, insulin…
- Trial name
- Hemo-PCOS (NCT06339567)
- Testing
- Thrombotic profile
- Where
- France
- Volunteers
- 352 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Polycystic Ovarian Syndrome (PCOS), Polyendocrine Metabolic Ovarian Syndrome (PMOS)
Comparison of Clomiphene Alone Versus Clomiphene Plus Sildenafil for Ovulation in Women With Polycystic Ovary Syndrome
The goal of this randomized clinical trial is to compare the effectiveness of clomiphene citrate alone with clomiphene citrate combined with sildenafil citrate for inducing ovulation and achieving pregnancy in women with…
- Trial name
- NCT07769476
- Testing
- Clomiphene Citrate 100 mg, Sildenafil Citrate 25Mg Tab
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Nishtar Medical University
Polycystic Ovarian Syndrome (PCOS)
This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms.
The rationale for this study is to observe the impact of a consumer-grade commercially available product called Milamend Hormone Balance on quality of life and hormonal health in women with self-reported symptoms associated with…
- Trial name
- NCT07764328
- Testing
- A dietary supplement powder for women
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Mila Mend Inc.
Polycystic Ovary Syndrome (PCOS) Women, Insulin Resistance Syndrome
Relationship Between Metformin Treatment, Anemia, and Erythropoietin Levels in Women With Polycystic Ovary Syndrome in Jordan
This prospective longitudinal interventional study aims to evaluate the effects of routine metformin therapy on metabolic, iron-related, erythropoietin, lipid, and hematological parameters in adult women with polycystic ovary…
- Trial name
- Metformin-APO (NCT07759674)
- Testing
- Metformin
- Where
- Jordan
- Volunteers
- 25 people
- Sponsor
- Jerash Private University
Polycystic Ovary Syndrome, Familial Partial Lipodystrophy
Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS)
Diagnostic case-control study (1 case for 2 controls). Inclusion of patients with severe insulin resistance syndrome of genetic origin, then inclusion of controls: patients examined for PCOS in day hospital with matching age (+/…
- Conditions
- Polycystic Ovary Syndrome, Familial Partial Lipodystrophy, LMNA (LaMin Nuclear A) Related Disorders
- Trial name
- ANDROLIPO (NCT07412028)
- Testing
- Genetic analysis, Biological analysis, imaging test
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris