Clinical trials: Polycystic Ovary Syndrome
Infertility, Female, Polycystic Ovary Syndrome
Letrozole for Frozen Embryo Transfer (FET) in Patients With Polycystic Ovary Syndrome (PCOS)
To offer patients with oligomenorrhoea or amenorrhoea an alternative to frozen embryo transfer in an artificial cycle, endometrial preparation using letrozole may be a valuable option.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, IVF, Ovulation Disorder
- Trial name
- LEFT (NCT04002635)
- Testing
- Letrozole, estradiol valerate
- Volunteers
- healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Polycystic Ovary Syndrome, IVF
Follicular Fluid Raman Shifts and IVF Outcomes
This study intends to collect about 150 cases of follicular fluid samples from PCOS and non-PCOS infertility patients undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles (in clinical…
- Trial name
- NCT04838535
- Testing
- Raman spectrum
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility, Female, PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
The Effects of Acetyl-L-Carnitine and Myo/Chiro-Inositol in Patients With PCOS
The large number of women in their child bearing age is affected by Polycystic ovarian syndrome (PCOS) leading to infertility. However it is considered as a multisystem disorder with comorbidities rather than a gynecological and…
- Trial name
- PCOS (NCT05767515)
- Testing
- metformin
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Khyber Medical University Peshawar
Polycystic Ovary Syndrome
Myo-inositol Versus Metformin in Obese Women With Polycystic Ovary Syndrome
The aim of this study is to compare the effects of six months treatment of two insulin-lowering therapies on the clinical and endocrine-metabolic parameters in obese women affected by polycystic ovary syndrome.
- Trial name
- NCT01791647
- Testing
- metformin 1500 mg, myoinositol 1500 mg
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Polycystic Ovarian Syndrome
Comparison of Bone Morphogenetic Protein-4 (BMP-4) and 7 Levels Between Control and Polycystic Ovarian Syndrome (PCOS) Patients.
The investigators aim to compare the levels of bone morphogenetic protein-4 and -7 (BMP-4 and 7) in blood, follicular fluid and ovarian organ culture supernatant obtained from healthy subjects and polycystic ovarian syndrome…
- Trial name
- NCT01162447
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- V.K.V. American Hospital, Istanbul
Polycystic Ovary Syndrome
Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity
In the present study, serum chitotriosidase activity and its relationship with insulin resistance were determined in patients with Polycystic Ovary Syndrome (PCOS).
- Trial name
- NCT01382576
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Polycystic Ovary Syndrome, Metabolic Syndrome
Lifestyle Intervention for Polycystic Ovary Syndrome: Pulse-Based Diet and Exercise
The purpose of our study is to evaluate the effectiveness of a lifestyle program for women with Polycystic Ovary Syndrome (PCOS). The investigators want to assess the effect of a pulse-based diet (i.e.
- Trial name
- NCT01288638
- Testing
- Pulse-based diet, TLC diet
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- University of Saskatchewan
Polycystic Ovarian Syndrome
Effects of Traditional Moderate Intensity Training and High Intensity Interval Training in Polycystic Ovarian Syndrome
To determine the comparative effects of traditional moderate intensity training and high intensity interval training on Anxiety, fatigue and Quality of Life in females with polycystic ovarian syndrome
- Trial name
- NCT06303219
- Testing
- RADITIONAL MODERATE INTENSITY TRAINING, HIGH INTENSITY INTERVAL TRAINING
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Polycystic Ovary Syndrome
Efficacy of Metformin in PCOS: Metabolic and Hormonal Factors
Hypothesis: Metformin treatment normalises hormone values and metabolic parameters in women with PCOS. Ovulation is restored and bleeding periods become regular.
- Trial name
- NCT00317928
- Testing
- Metformin
- Volunteers
- 50 people
- Sponsor
- Aarhus University Hospital Skejby
Polycystic Ovary Syndrome
Serum Metabolomics Study of Traditional Chinese Medicine Formula （Shen Qi Tiao Ti Formula） Intervention to Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a most common, heterogeneous, complex endocrinopathy disease.Traditional Chinese medicine (TCM) has been used in the treatment of PCOS for many years.
- Trial name
- NCT03623451
- Testing
- Chinese Medicine Formula
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Heilongjiang University of Chinese Medicine
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Obese
Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome
Girls and women 12-35 years old with obesity and polycystic ovarian syndrome who are on or off metformin, will receive a glucagon like peptide-1 receptor agonist intervention for 10 months to induce metabolic changes, weight loss…
- Trial name
- RESTORE (NCT05819853)
- Testing
- Semaglutide Injectable Product (Wegovy and/or Ozempic)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Colorado, Denver
PCOS (Polycystic Ovary Syndrome)
Letrozole 5 mg for 10 Days Versus Letrozole 10 mg for 5 Days for Ovarian Stimulation in PCOS
The goal of this clinical trial is to learn if drug letrozole 5mg for 10 days works better than letrozole 10mg for 5 days for ovarian stimulation in infertile women with PCOS.
- Trial name
- PCOS OID (NCT07448272)
- Testing
- Tab letrozole 5mg for 10 days, Tabletrozole 10mg for 5 days
- Where
- Bangladesh
- Volunteers
- 80 people
- Sponsor
- Mst.Sumyara Khatun
Kallmann Syndrome, Hypogonadotropic Hypogonadism
Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate
The purpose of this study is to explore the genetic basis of reproductive disorders and cleft lip and/or palate.
- Conditions
- Kallmann Syndrome, Hypogonadotropic Hypogonadism, Hypothalamic Amenorrhea, Polycystic Ovarian Syndrome
- Trial name
- NCT01601171
- Where
- Switzerland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Polycystic Ovary Syndrome
Gut Microbiome in Patients With Polycystic Ovary Syndrome
The polycystic ovary syndrome is intimately associated with body weight and nutrition.The genomic era did not bring a breakthrough to the understanding of the syndrome.
- Trial name
- NCT02078505
- Testing
- diet
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Clomiphene Citrate Resistant Polycystic Ovary Syndrome
NAC in CC Resistant PCOS After LOD
This prospective randomized placebo-controlled double blind clinical trial will conducted in Ain Shams University maternity Hospital including 120 women diagnosed with clomiphene citrate resistant polycystic ovary syndrome.
- Trial name
- NAC (NCT02775734)
- Testing
- N-acetyl-cysteine, Clomiphene citrate
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome
Effect of Dosage of Metformin on Menstruation and Lipid Profile in Women With Polycystic Ovary Syndrome
Polycystic ovarian syndrome (PCOS) is the most common cause of anovulatory infertility and causes menstrual disruption in 6.6-6.8% of women in reproductive age and is characterized by insulin resistance, hyperinsulinemia…
- Trial name
- NCT01474967
- Testing
- Metformin
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Hormozgan University of Medical Sciences
PCOS (Polycystic Ovary Syndrome)
Letrozole and Cabergoline Versus Letrozole Alone in Ovulation Induction
Polycystic Ovarian Syndrome (PCOS) is the most common endocrine disorders in women of reproductive age. According to the World Health Organization (WHO) estimation revealed over 116 million women (3.4%) are affected by PCOS…
- Trial name
- NCT07168837
- Testing
- Letrozole tablets
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Polycystic Ovarian Syndrome, Infertility
Healthy Eating for Reproductive Health: Greenville
This study will be a 6-month intervention that is examining how different dietary approached may be useful for women with Polycystic Ovarian Syndrome (PCOS) who are attempting pregnancy, particularly by measuring changes in…
- Conditions
- Polycystic Ovarian Syndrome, Infertility, Obesity, Overweight
- Trial name
- HER Health (NCT01716429)
- Testing
- Vegan diet, Low calorie diet
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of South Carolina
Polycystic Ovary Syndrome (PCOS), Obesity
Effects of GLP-1RAs on Fertility Outcomes in Obese Women With PCOS
The goal of this clinical trial is to examine whether GLP1-RA and healthy lifestyle education in women with PCOS and obesity prior to fertility treatment improves live birth rate and other reproductive, maternal and perinatal…
- Conditions
- Polycystic Ovary Syndrome (PCOS), Obesity, Infertility, Female
- Trial name
- NCT07687667
- Testing
- GLP-1 receptor agonist, Metformin
- Where
- China
- Volunteers
- 406 people
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome
Combined Metformin and Clomiphene Citrate (CC) or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to compare and determine the efficacy of combined metformin and Clomiphene citrate administration to that of laparoscopic ovarian diathermy (LOD) in infertile women with Polycystic ovary syndrome…
- Trial name
- NCT00969631
- Testing
- metformin HCl (Cidophage®; CID,Cairo, Egypt), CC (Clomid®; Global Napi Pharmaceuticals,Cairo, Egypt),Cairo, Egypt), Laparoscopic ovarian diathermy (LOD)
- Where
- Egypt
- Volunteers
- 282 people
- Sponsor
- Mansoura University
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