Clinical trials: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome, Healthy
Vitamin D Treatment, Pharmacogenetics and Glucose Metabolism
Background: Polycystic ovary syndrome (PCOS) is as common as 5-10% of all women in Austria. PCOS women frequently present with metabolic disturbances, hyperandrogenism and infertility. New therapy concepts are warranted.
- Conditions
- Polycystic Ovary Syndrome, Healthy, Vitamin D Deficiency
- Trial name
- NCT01721915
- Testing
- Vitamin D supplementation
- Where
- Austria
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Pioglitazone
Pioglitazone Versus Metformin as First Treatment in Infertile Women With Polycystic Ovary Syndrome
Participants with PCOS will be divided into two groups then each group will randomly recieve one of the following treatment 1. metformin will be adminstered in adose of 500 mg 3 times daily for 3 months to group B. 2.
- Trial name
- NCT03566225
- Testing
- Pioglitazone, Metformin, Clomiphene Citrate
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anovulation, Polycystic Ovary Syndrome
Ovarian Laser Treatment in Women With Polycystic Ovarian Syndrome: A Randomized Study on the Laser Dose
BACKGROUND: A new effective way, transvaginal ultrasound-guided ovarian interstitial laser-coagulation treatment, in management of anovulation in patients with polycystic ovary syndrome (PCOS), has been presented in the data…
- Conditions
- Anovulation, Polycystic Ovary Syndrome, Infertility
- Trial name
- NCT00643708
- Testing
- ovarian interstitial laser treatment
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Shen-Zhen City Maternity and Child Healthcare Hospital
Polycystic Ovarian Syndrome (PCOS)
Effect of Theronomic Ova-All Care on Biomarkers of Ovarian Health in Adult Female With Polycystic Ovarian Syndrome
Theronomic Ova-All Care is a tribiotic health product aimed at improving ovarian health in people with polycystic ovarian syndrome (PCOS).
- Trial name
- Ova-All Care (NCT06963840)
- Testing
- Theronomic Ova-All Care
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Wellizen Australia
Polycystic Ovary Syndrome
Effect of Vitamin D on Hormonal, Metabolic and Cardiovascular Risk Factors in Patients With Polycystic Ovary Syndrome
This is a double blind randomised placebo-controlled study involving women with polycystic ovary syndrome (PCOS). The patients will be randomised either to Vitamin D 3200 IU or placebo for three months.
- Trial name
- NCT02513381
- Testing
- Vitamin D3, 3200IU
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Polycystic Ovarian Syndrome
Letrozole Combined With Gonadotropins (Gn) for Ovarian Stimulation Undergoing in Vitro Fertilization/Intracytoplasmic Sperm Injection (IVF/ICSI) in Patients With Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine whether letrozole combined with gonadotropins are effective in the ovarian hyperstimulating for IVF/ICSI in patients with PCOS.
- Trial name
- NCT00894608
- Testing
- letrozole + gonadotropins, GnRHa + gonadotropins
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Yunyang Medical College
Polycystic Ovary Syndrome
Insulin Resistance, Polycystic Ovary Syndrome, and Bone Research Study
The purpose is to investigate the effects of 2 different treatments (drospirenone/ethinyl estradiol versus rosiglitazone) on insulin sensitivity and androgen levels, inflammatory markers, vascular markers and bone development in…
- Trial name
- NCT00640224
- Testing
- rosiglitazone, drospirenone/ethinyl estradiol
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Silva Arslanian
Polycystic Ovarian Syndrome (PCOS), Irregular Menstrual Cycles
Effect of a Commonly Used Antibiotic, Doxycycline, in Women With Polycystic Ovarian Syndrome
The purpose of this study is to study the effect of a commonly used antibiotic, doxycycline, on the production of ovarian hormones and menstrual cycles in women with Polycystic Ovarian Syndrome (PCOS).
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Irregular Menstrual Cycles, Androgen Excess
- Trial name
- MI-PCOS (NCT01788215)
- Testing
- doxycycline, Sugar Pill
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Rochester
IVF, Oocyte Maturation Defect 1
IVF Outcome Following Progestogen Ovarian Stimulation
The new strategy is by using the progestogen to block the luteinizing hormone(LH) surge either endogenous during luteal phase stimulation, or exogenous in the follicular phase i.e progestin primed ovarian stimulation (PPOS).
- Conditions
- IVF, Oocyte Maturation Defect 1, Clinical Pregnancy Rate, Ovarian Hyperstimulation
- Trial name
- NCT04175990
- Testing
- Dydrogesterone Pill
- Where
- Malaysia
- Volunteers
- 155 people
- Sponsor
- National University of Malaysia
Polycystic Ovarian Syndrome (PCOS)
Longitudinal Metabolic Assessment in PCOS
This prospective observational cohort study aims to evaluate longitudinal changes in metabolic status and cardiopulmonary exercise capacity in women with polycystic ovary syndrome (PCOS).
- Trial name
- PCOS-CPET (NCT07869017)
- Testing
- the investigators give inositol for two months.
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Karadeniz Technical University
PCOS
Genetics of Polycystic Ovary Syndrome
The purpose of this study is to look at genes (DNA) and how they affect health and disease. Genes are the instruction manual for the body. The genes you get from your parents decide what you look like and how your body behaves.
- Trial name
- NCT00647335
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- University of Pennsylvania
Pregnancy, Polycystic Ovary Syndrome
Metformin and Folate in Pregnant Polycystic Ovary Syndrome(PCOS) Women
A more recent prospective nonrandomized placebo-controlled double-blind clinical study demonstrated that metformin exerts a slight but significant deleterious effect on serum homocysteine (Hcy) levels in patients with PCOS, and…
- Trial name
- NCT01115140
- Testing
- Metformin plus folic acid
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Polycystic Ovary Syndrome (PCOS) Women, Insulin Resistance Syndrome
Relationship Between Metformin Treatment, Anemia, and Erythropoietin Levels in Women With Polycystic Ovary Syndrome in Jordan
This prospective longitudinal interventional study aims to evaluate the effects of routine metformin therapy on metabolic, iron-related, erythropoietin, lipid, and hematological parameters in adult women with polycystic ovary…
- Trial name
- Metformin-APO (NCT07759674)
- Testing
- Metformin
- Where
- Jordan
- Volunteers
- 25 people
- Sponsor
- Jerash Private University
Polycystic Ovary Syndrome
Pharmacogenetics of Metformin Action in PCOS
1. The polycystic ovary syndrome is the major cause of infertility in the United States. Metformin has been shown to increase frequency of ovulations in PCOS, and is used in clinical practice to treat infertility, but some women…
- Trial name
- NCT00703508
- Testing
- Metformin 500 mg tablet
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Virginia Commonwealth University
Polycystic Ovary Syndrome
Expression of CVD and HA Between Obesity and Non-obesity Polycystic Ovary Syndrome (PCOS) Women in Taiwan
Polycystic Ovarian Syndrome (PCOS) is the most common endocrine disorder in reproductive women. It is estimated that 5 to 10% of women of reproductive age have PCOS.
- Trial name
- NCT01113918
- Where
- Taiwan
- Volunteers
- 627 people
- Sponsor
- Taipei Medical University WanFang Hospital
Polycystic Ovary Syndrome
Cinnamon and COH in PCOS Women Underdoing IVF/ICSI Cycles
In patients with polycystic ovary syndrome, insulin resistance increases, and since the extracts from cinnamon reduces insulin resistance by two mechanisms (1- increasing activation of the IRS/PI-3 kinase insulin signaling…
- Trial name
- NCT06199024
- Testing
- Oral cinnamon supplementation
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Royan Institute
Infertility, Female, PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
The Effects of Acetyl-L-Carnitine and Myo/Chiro-Inositol in Patients With PCOS
The large number of women in their child bearing age is affected by Polycystic ovarian syndrome (PCOS) leading to infertility. However it is considered as a multisystem disorder with comorbidities rather than a gynecological and…
- Trial name
- PCOS (NCT05767515)
- Testing
- metformin
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Khyber Medical University Peshawar
Polycystic Ovary Syndrome
Impact of Metformin on In Vitro Fertilization Outcomes in Overweight and Obese PCOS Women
RCT to investigate whether metformin co-treatment would improve IVF outcomes in overweight and obese women with PCOS.
- Trial name
- NCT02910817
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Assiut University
Polycystic Ovary Syndrome
The Effect of Dipeptidyl Peptidase 4 Inhibition on Growth Hormone Secretion in Women With Polycystic Ovarian Syndrome
Adults with abdominal obesity are at high risk for cardiovascular disease and also exhibit diminished growth hormone (GH) secretion; the latter further contributes to the development of visceral adiposity, impaired fibrinolysis…
- Trial name
- NCT02122380
- Testing
- Sitagliptin
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Vanderbilt University
PCOS (Polycystic Ovary Syndrome)
The Physical and Mental Impact of ART: IVM vs Conventional Ovarian Stimulation
Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine conditions, affecting around 10% of women in reproductive age (ESHRE PCOS guideline, 2023).
- Trial name
- QolART (NCT07274202)
- Testing
- Questionnaires
- Volunteers
- 84 people
- Sponsor
- Universitair Ziekenhuis Brussel
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