Clinical trials: Polycystic Ovary Syndrome
Menstrual Cycle, Ovulation
Apple Women's Health Study
This is an observational longitudinal study to advance the understanding of menstrual cycle and gynecologic health conditions including PCOS, infertility and breast cancer.The study will be hosted within the Research…
- Conditions
- Menstrual Cycle, Ovulation, Menstruation, Polycystic Ovary Syndrome
- Trial name
- NCT04196595
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Coenzyme q10
Coenzyme q 10 and Fertility Outcome in Women With Clomiphene Resistant PCOS
The study evaluates the effect of coenzyme q 10 on ovulation and subsequent pregnancy in women with polycystic ovarian syndrome.
- Trial name
- NCT04302532
- Testing
- Coenzyme Q10, clomiphene citrate
- Where
- Pakistan
- Volunteers
- 149 people
- Sponsor
- Karachi Medical and Dental College
Anovulation, Obesity
An RCT of Metformin Vs Orlistat in Obese Anovulatory Women
This study aims to investigate the role of the weight reduction agent, Orlistat compared to the Metformin for the management of women who are obese and do not ovulate or have difficulty conceiving.
- Trial name
- NCT00292799
- Testing
- Orlistat Vs Metformin
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Polycystic Ovary Syndrome, Dietary Habits
Comparison of Lifestyle Markers Between Women With and Without Polycystic Ovary Syndrome
The purpose of the study is to identify lifestyle factors associated with PCOS and understand how diet and activity levels impact features of PCOS.
- Conditions
- Polycystic Ovary Syndrome, Dietary Habits, Physical Activity
- Trial name
- NCT01859663
- Where
- 3 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Cornell University
Polycystic Ovarian Syndrome (PCOS)
This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms.
The rationale for this study is to observe the impact of a consumer-grade commercially available product called Milamend Hormone Balance on quality of life and hormonal health in women with self-reported symptoms associated with…
- Trial name
- NCT07764328
- Testing
- A dietary supplement powder for women
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Mila Mend Inc.
Adverse Effects of Medical Drugs
Effects of Isotretinoin on The Gonads and Hirsutism
The investigators consider that there are some rising concerns about the use of isotretinoin by women of reproductive age with depleted ovarian reserve, hence it is important to detect the effect of isotretinoin on ovarian…
- Trial name
- NCT02855138
- Testing
- oral isotretinoin
- Volunteers
- 80 people
- Sponsor
- Kayseri Education and Research Hospital
Polycystic Ovary Syndrome
Auricular Acupressure (AA) For Overweight/Obese Adolescent and Young Polycystic Ovary Syndrome ( PCOS)
The purpose of this trial is to investigate the effect and safety of auricular acupressure on adolescent and young women with PCOS.
- Trial name
- NCT02326714
- Testing
- Auricular acupressure
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Polycystic Ovary Syndrome
Effect of Nicotinic Acid on Cardiovascular Risks Indices in Polycystic Ovary Syndrome
Niacin will improve postprandial hyperlipidaemia and cardiovascular risks indices via its lipid lowering as well as via pleiotropic effects in patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT01118598
- Testing
- tredaptive (nicotinic acid/ laropiprant)
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
PCOS, Insulin Resistance
Effect of Bromocriptine on Insulin Resistance in Polycystic Ovarian Syndrome - A Pilot Study
The primary aim of this study is to determine the effect of dopamine agonist therapy on insulin resistance in lean vs. obese women with polycystic ovary syndrome.
- Trial name
- PCOS-Pilot (NCT02133755)
- Testing
- Bromocriptine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- IWK Health Centre
Polycystic Ovary Syndrome
Treating Obese PCOS Patients With LSG vs. Met
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to 15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation disorders and/or hyperandrogenemia, and often…
- Trial name
- NCT04508634
- Testing
- laparoscopic sleeve gastrectomy, Metformin Pill
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai 10th People's Hospital
Polycystic Ovary Syndrome, Metformin
Effects of Metformin on Metabolic and Reproductive Outcomes in Chinese PCOS Patients
Polycystic ovary syndrome (PCOS) is a reproductive endocrine disease characterized by reproductive and metabolic abnormalities, which is a crucial cause of female infertility and an essential risk factor for type 2 diabetes.
- Trial name
- NCT05463627
- Testing
- Metformin
- Where
- China
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Polycystic Ovarian Syndrome, Infertility
Healthy Eating for Reproductive Health (HERHealth)
This study will be a 6-month intervention that is examining how different dietary approached may be useful for women with Polycystic Ovarian Syndrome (PCOS) who are attempting pregnancy, particularly by measuring changes in…
- Conditions
- Polycystic Ovarian Syndrome, Infertility, Obesity, Overweight
- Trial name
- HERHealth (NCT01509066)
- Testing
- Diet
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
PCOS
An Integrated Self-Management Intervention for Adolescents With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder, affecting 7%-18% of reproductive-age women. Women with PCOS are at increased risk for a number of adverse physical and mental health outcomes.
- Trial name
- NCT03600337
- Testing
- Working to Optimize Wellness in Tees with PCOS (WOW)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Texas at Austin
Polycystic Ovary Syndrome, Infertility, Female
GnRH Agonist Plus Hormone Replacement Therapy vs Hormone Replacement Therapy on IVF Outcomes
The study is conducted at Arash Women's Hospital on all women undergoing the frozen embryo transfer cycle. Patients who signed informed consent will be randomly divided into two groups.
- Trial name
- NCT05189873
- Testing
- Long GnRH agonist + HRT, HRT
- Where
- Iran
- Volunteers
- 128 people
- Sponsor
- Tehran University of Medical Sciences
Polycystic Ovary Syndrome
Mean Platelet Volume and TXA2 Levels in Patients With Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS)is closely associated with insulin resistance and hyperinsulinemia as well as with increased incidence in diabetes, hypertension, dyslipidemia and atherosclerosis.
- Trial name
- NCT01538602
- Where
- Italy
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Polycystic Ovary Syndrome (PCOS), Menstrual Irregularity
Ovarian Ultrasonography for the Clinical Evaluation of Polycystic Ovary Syndrome
The investigators would like to determine how aspects of adiposity and age influence ultrasound features of the ovaries which are used to diagnose polycystic ovarian syndrome (PCOS).
- Conditions
- Polycystic Ovary Syndrome (PCOS), Menstrual Irregularity, Overweight and Obesity
- Trial name
- NCT03547453
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Cornell University
Unexplained Infertility, Polycystic Ovarian Syndrome
Endocrine Disrupting Chemicals: Potential Effects on Male and Female Reproductive Health in Saskatchewan
The overall objective of this study is to determine whether serum BPA and/or phthalate concentrations differ in fertile versus infertile men and women in Saskatchewan. The investigators will test the following hypothesis: 1.
- Conditions
- Unexplained Infertility, Polycystic Ovarian Syndrome, Male Infertility
- Trial name
- NCT02272439
- Where
- Canada
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Polycystic Ovary Syndrome, Familial Partial Lipodystrophy
Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS)
Diagnostic case-control study (1 case for 2 controls). Inclusion of patients with severe insulin resistance syndrome of genetic origin, then inclusion of controls: patients examined for PCOS in day hospital with matching age (+/…
- Conditions
- Polycystic Ovary Syndrome, Familial Partial Lipodystrophy, LMNA (LaMin Nuclear A) Related Disorders
- Trial name
- ANDROLIPO (NCT07412028)
- Testing
- Genetic analysis, Biological analysis, imaging test
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Effect of Metformin on Patients With Polycystic Ovary Syndrome
The purpose of the study is to understand the effect of Metformin on patients with PCOS.
- Trial name
- NCT05802212
- Testing
- Metformin intervention for 12 weeks
- Where
- China
- Volunteers
- 77 people
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome, Anovulation
LOD vs Gn in Anovulatory PCOs Resistant to First Line Agents
PCOS is a complex disease that is diagnosed by the presence of two of the following three: oligo/anovulation, clinical and/or biochemical hyperandrogenism, or polycystic ovaries by ultrasound .
- Trial name
- NCT04325295
- Testing
- Laparoscopic ovarian drilling, Recombinant FSH (rFSH)
- Volunteers
- 200 people
- Sponsor
- Assiut University