Clinical trials: Polycystic Ovary Syndrome
Polycystic Ovary, Progesterone Resistance
Progesterone Action on Endometrium of PCOS
Objective: To study the influence of metabolic factors on the action of progesterone on the endometrium of women with PCOS. Design: A prospective open-label clinical trial.
- Trial name
- NCT05062135
- Testing
- Progesterone 400 Mg Vaginal Suppository on PCOS
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group;, At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether;
The Potential Biochemical Diagnosis Criteria and Therapeutic Effect Indexes: Sex Hormone Binding Globulin Levels and Free Androgen Index in Blood of Patients With Polycystic Ovary Syndrome
To explore whether Free androgen index（FAI）can be regarded as biochemically diagnostic indexes of high androgen hormone in blood of patients with Polycentric ovary syndrome（PCOS）.
- Conditions
- The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group;, At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether;, 534 Patients in the Cases Group and 580 Women in the Control Group Received no Measures, While 579 Patients Received Drugs;, The Investigators Monitored Basic Indexes in Blood of All the Subjects in This Suvey,and Also Monitored Indexes of 579 Patients After Treatment.
- Trial name
- NCT01784380
- Testing
- Diane-35;metformin;Clomiphene citrate; Human menopausal gonadotropin
- Where
- 2 sites in China
- Volunteers
- 1,159 people
- Sponsor
- Zhongshan Bo Ai Hospital
Pioglitazone
Pioglitazone Versus Metformin as First Treatment in Infertile Women With Polycystic Ovary Syndrome
Participants with PCOS will be divided into two groups then each group will randomly recieve one of the following treatment 1. metformin will be adminstered in adose of 500 mg 3 times daily for 3 months to group B. 2.
- Trial name
- NCT03566225
- Testing
- Pioglitazone, Metformin, Clomiphene Citrate
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome
Low Dose Growth Hormone in Obese PCOS Women
Study hypothesis: Growth hormone (GH), through its generation of free 'bioavailable' insulin-like growth factor (IGF)-I, can improve insulin sensitivity and the metabolic profile of women with polycystic ovary syndrome.
- Trial name
- NCT00518635
- Testing
- Nutropin
- Where
- United States
- Sponsor
- Oregon Health and Science University
Polycystic Ovary Syndrome
Adipose Tissue Function and Response to Exercise Training in Women With and Without Polycystic Ovary Syndrome
The primary aim of this trial is to investigate adipose tissue function in women with and without polycystic ovary syndrome (PCOS). PCOS is a common endocrine disorder in young women.
- Trial name
- HIT-FAT (NCT02943291)
- Testing
- 4x4 minutes high intensity interval training, 10x1 minute high intensity interval training
- Where
- 2 sites in Australia, Norway
- Volunteers
- 15 people
- Sponsor
- Norwegian University of Science and Technology
Polycystic Ovary Syndrome, Gingivitis
Evaluation of the Effect of Non-Surgical Periodontal Treatment in Women With Polycystic Ovary Syndrome
The goal of this clinical trial is to compare women with polycystic ovary syndrome and systemically healthy woman in relation to their gums and gum treatment outcomes as well as to investigate the role of a new biomarker in gum…
- Trial name
- NCT06567132
- Testing
- Non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Polycystic Ovary Syndrome
The Changes of Body Fat Distribution in Obese Patients With PCOS After LSG
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to 15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation disorders and/or hyperandrogenemia, and often…
- Trial name
- NCT04690634
- Testing
- laparoscopic sleeve gastrectomy (LSG)
- Where
- China
- Volunteers
- 153 people
- Sponsor
- Shanghai 10th People's Hospital
Polycystic Ovary Syndrome
Extended-release vs Immediate-release Metformin in PCOS Women
The aim of our study is to compare the different effects of 6 months treatment with extended-release metformin and immediate-release metformin on clinical, endocrine and metabolic parameters in women affected by polycystic ovary…
- Trial name
- NCT02984722
- Testing
- Metformin
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Catholic University of the Sacred Heart
Infertility
The Effect of Ethinyl Estradiol on Polycystic Ovary Syndrome Women Undergoing Intrauterine Insemination
According to the studies CC is successful at inducing ovulation in 50%-75% of cases, but only 30-40% becomes pregnant. The difference has been attributed to a negative action of clomifen citrate(CC) in the form of prolonged…
- Trial name
- NCT01219101
- Testing
- clomiphene citrate with ethinyl esteradiol, clomiphene citrate with plasebo
- Where
- Iran
- Volunteers
- 95 people
- Sponsor
- Royan Institute
Infertility, Poly Cystic Ovary Syndrome
The Effectiveness of CPII for Infertility Induced by PCOS in China
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age and is associated with metabolic, reproductive and mental health complications.
- Trial name
- CPII-PCOS-I (NCT07906756)
- Testing
- Standard Treatment for PCOS-Induced Infertility, Counselling-Integrated Standard Care for PCOS-Induced Infertility, Personalized Care-Integrated Intervention (PII)
- Where
- 4 sites in China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Polycystic Ovary Syndrome
Oral Contraceptive and Cardiovascular Risk in PCOS
Oral contraceptive therapy is routinely used for the treatment of menstrual disturbances of patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT00593294
- Testing
- Physical exercise, OC - Drospirenone plus Ethynylestradiol, Vitamin, polyvitamins tablets
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federico II University
Polycystic Ovary Syndrome
Analysis of Clinical Characteristics and Study of Diagnostic Markers in Patients with Polycystic Ovary Syndrome
The investigators collected clinical data and serum samples of patients with polycystic ovary syndrome in this study, used statistical software such as SPSS for data analysis, and used experimental techniques such as ELISA to…
- Trial name
- NCT05063383
- Testing
- This study does not involve any interventions
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai 10th People's Hospital
Ovarian Cysts
Ultrasonographic Evaluation of Ovarian Stromal Vascularity in Women With Polycystic Ovary Syndrome (PCOS)
The most common endocrine condition in reproductive women is polycystic ovary syndrome. It has a prevalence of 5-10%. According to the Rotterdam criteria, oligo/anovulation, clinic or biochemical hyperandrogenism, PCOS morphology…
- Trial name
- NCT05418595
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Usak State Hospital
PCOS (Polycystic Ovary Syndrome)
Letrozole 5 mg for 10 Days Versus Letrozole 10 mg for 5 Days for Ovarian Stimulation in PCOS
The goal of this clinical trial is to learn if drug letrozole 5mg for 10 days works better than letrozole 10mg for 5 days for ovarian stimulation in infertile women with PCOS.
- Trial name
- PCOS OID (NCT07448272)
- Testing
- Tab letrozole 5mg for 10 days, Tabletrozole 10mg for 5 days
- Where
- Bangladesh
- Volunteers
- 80 people
- Sponsor
- Mst.Sumyara Khatun
Polycystic Ovary Syndrome
High-Intensity Interval Training On Women With Polycystic Ovary Syndrome.
This RCT is aimed towards determining the effectiveness of exercises based intervention strategy involving high intensity interval training exercises in improving serum testosterone level, body fat composition and physical…
- Trial name
- NCT04942366
- Testing
- High intensity interval training, Strength training
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Ziauddin University
PCOS
Sitagliptin Improved Beta Cell Function and Prevented a Conversion Rate to Impaired Glucose Tolerance and Type 2 Diabetes in Metformin Intolerant Obese Women With Polycystic Ovary Syndrome
Metformin is the first-line therapy for PCOS with high metabolic risk, yet a large proportion of patients cannot tolerate it due to associated gastrointestinal adverse events.
- Trial name
- NCT03122041
- Testing
- Sitagliptin, Lifestyle intervention
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Polycystic Ovary Syndrome
Clinical and Biochemical Presentation of Polycystic Ovary Syndrome in Different Age Group
To study the clinical and biochemical characteristics women with polycystic ovary syndrome (PCOS) in different aged groups.
- Trial name
- NCT01350895
- Where
- Taiwan
- Volunteers
- 781 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Polycystic Ovary Syndrome
Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients
The purpose of this study was to determine whether metformin combined with exenatide once weekly (EQW) is more effective than metformin alone in the treatment of overweight/obese women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT04029272
- Testing
- Metformin, Exenatide 2 MG
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking Union Medical College Hospital
IVM, PCOS (Polycystic Ovary Syndrome)
Low vs. Air Oxygen Concentration CAPA-IVM Culture of Cumulus-oocyte Complexes
IVM with a pre-maturation step, known as capacitation IVM (CAPA-IVM), has demonstrated enhanced maturation of human oocytes in vitro and successful live births.
- Trial name
- NCT06087354
- Testing
- The way of Cumulus-oocyte complexes (COC) CAPA-IVM culture condition
- Where
- Vietnam
- Volunteers
- 20 people
- Sponsor
- Mỹ Đức Hospital
Polycystic Ovary Syndrome (PCOS)
Effects of Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients
The purpose of this study is to determine whether micronized trans-resveratrol improves clinical (excessive hair, menstrual cycle), endocrine (androgens)and metabolic (lipids, markers of systemic inflammation) in women with…
- Trial name
- NCT01720459
- Testing
- Micronized trans-resveratrol
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Poznan University of Medical Sciences
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