Clinical trials: Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS)
Mood and Nutrition Interventions in Polycystic Ovary Syndrome
The purpose of this study is to help determine the best treatment plan for women with PCOS who are overweight or obese and experiencing significant symptoms of depression and anxiety.
- Trial name
- MANI-PCOS (NCT01899001)
- Testing
- Cognitive Behavioral Therapy, Nutrition Counseling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
Atherosclerosis, Cardiovascular Diseases
Risk of Coronary Heart Disease in Women With Polycystic Ovary Syndrome
To investigate whether women with Polycystic Ovary syndrome (PCOS) have evidence of an increased prevalence rate of subclinical atherosclerosis as measured by the presence of plaque, increased intima-medial carotid artery wall…
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Carotid Artery Diseases
- Trial name
- NCT00005459
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pre-Eclampsia, Intrauterine Growth Restriction
PEPPI Study: Identification of Women at Risk for Placental Dysfunction
The main purpose of this study is to evaluate Fetal Medicine Foundation's pre-eclampsia risk calculator using maternal characteristics, first trimester serum placental growth factor (PlGF) and mean arterial pressure (MAP) in a…
- Conditions
- Pre-Eclampsia, Intrauterine Growth Restriction, Polycystic Ovary Syndrome, Iron-deficiency
- Trial name
- NCT06115122
- Testing
- Pre-eclampsia screening program
- Where
- Finland
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Oulu University Hospital
Polycystic Ovary Syndrome
Effect of Aerobics on Physical and Mental Health in Polycystic Ovary Syndrome
Polycystic ovary is one of the most common metabolic and endocrine disorders in women of reproductive age group. The Rotterdam criteria are used internationally for its diagnosis.
- Trial name
- NCT05577949
- Testing
- Structured aerobics exercise
- Where
- 4 sites in Pakistan
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Muhammad Irfan
PCOS, Obesity
PDE-4 Inhibitor Roflumilast and GLP-1 Agonist Liraglutide in Polycystic Ovary Syndrome
The purpose of this study was to determine whether monotherapy treatment with phosphodiesterase-4 (PDE-4) inhibitor roflumilast is more effective than treatment with glucagon-like protein 1 (GLP-1) liraglutide or treatment with…
- Trial name
- NCT02187250
- Testing
- metformin, liraglutide, roflumilast
- Where
- Slovenia
- Volunteers
- 45 people
- Sponsor
- University Medical Centre Ljubljana
PCOS (Polycystic Ovary Syndrome), Puberty
ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence
This study explores how a physical activity program can affect hormone health and diabetes risk in girls ages 8-12 who may be at higher risk.
- Conditions
- PCOS (Polycystic Ovary Syndrome), Puberty, Insulin Resistance, Physical Activity
- Trial name
- NCT07102797
- Testing
- ActiveGirls Physical Activity Program (Full), ActiveGirls Physical Activity Program (Delayed Lower Intensity)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Polycystic Ovary Syndrome (PCOS)
Fertility and Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and affects approximately 10% of women worldwide.
- Trial name
- FERTIOPK (NCT07499518)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 473 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Polycystic Ovary Syndrome
Clomiphene Stair-Step Protocol for Ovulation Induction in Women With Polycystic Ovarian Syndrome
The objective of our study is to evaluate the efficacy of the clomiphene stair-step protocol to induce ovulation in women with polycystic ovarian syndrome (PCOS) compared to traditional protocol.
- Trial name
- PCOSCCTvUSS (NCT01953796)
- Testing
- clomiphene
- Where
- Iraq
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kufa University
Infertility, Polycystic Ovarian Syndrome
Adding Prednisolone During Ovulation Induction With CC in Lean Women With CC Resistant PCOS
The purpose of this study is to evaluate the effect of concomitant administration of prednisolone during use of clomiphene citrate (CC) for induction of ovulation in infertile lean women having CC resistant polycystic ovarian…
- Trial name
- NCT02344888
- Testing
- Clomiphene citrate and Prednisolone, Clomiphene citrate and folic acid
- Where
- 2 sites in Egypt
- Volunteers
- 300 people
- Sponsor
- Mahmoud Thabet
Polycystic Ovary
The Supporting Understanding of PCOS Education and Research (SUPER) Study
This research will test whether a Dietary Approaches to Stop Hypertension (DASH) or a very low-carbohydrate diet better improves outcomes like blood glucose control and body weight for adults with polycystic ovary syndrome.
- Trial name
- SUPER (NCT05452642)
- Testing
- DASH diet, Very low-carbohydrate diet
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- University of Michigan
Polycystic Ovary Syndrome (PCOS)
Amelioration of Polycystic Ovary Syndrome Related Disorders by Supplementation of Thymoquinone and Metformin
Objective: To investigate the potential benefit of adding Thymoquinone to Metformin in alleviating symptoms of polycystic ovarian syndrome. Methods: 207 overweight and obese PCOS Patients were divided into two groups.
- Trial name
- NCT04852510
- Testing
- Metformin Versus a combination of Metformin and Thymoquinone (TQ)
- Where
- Saudi Arabia
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Saudi German Hospital - Madinah
Obesity, Polycystic Ovary Syndrome
Metformin and Gestational Diabetes in High-risk Patients: a RCTs
Gestational diabetes mellitus (DM) is one of the most frequent complications in pregnant patients with polycystic ovary syndrome (PCOS) in 20-40% of cases and ~40% of patients with gestational DM are likely to have underlying…
- Conditions
- Obesity, Polycystic Ovary Syndrome, Gestational Diabetes
- Trial name
- NCT00883259
- Testing
- Metformin
- Where
- 3 sites in Italy
- Volunteers
- 80 people
- Sponsor
- University Magna Graecia
Anovulation, Polycystic Ovary Syndrome
Circulating Androgen Levels Are Not Affected by the Administration of Vaginal Micronized Progesterone for Withdrawal Bleeding in Patients With Polycystic Ovarian Syndrome
Hormonal evaluation of women who are suspected of having Polycystic ovary syndrome (PCOS) involves the measurement of basal levels of androgens and 17-hydroxyprogesterone (17-OHP), which are generally used to establish the…
- Conditions
- Anovulation, Polycystic Ovary Syndrome, Hyperandrogenism
- Trial name
- NCT03088046
- Testing
- Micronized Progesterone
- Volunteers
- 15 people
- Sponsor
- Fundacion Dexeus
Infertility, PCOS
Metformin in Patients With PCOS and Predictors of Poor Ovarian Response Ongoing In-vitro Fertilization
Metformin should be administered with caution and could be potentially dangerous in infertile patients with PCOS who show a poor ovarian response and are undergoing gonadotropin-based ovarian stimulation.
- Conditions
- Infertility, PCOS, Prognosis for Poor Response
- Trial name
- NCT01208740
- Testing
- Metformin
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- University Magna Graecia
Polycystic Ovary Syndrome, Infertility
Progesterone Primed Ovarian Stimulation Protocol Versus Antagonist Protocol for PCO Patient
this study is designed to compare the Progesterone primed ovarian stimulation protocol versus the antagonist protocol as a method to stimulate PCO patients in ICSI cycles to decrease cost and decrease OHSS.
- Conditions
- Polycystic Ovary Syndrome, Infertility, IVF
- Trial name
- NCT05847660
- Testing
- Progesterone antagonist, conventional antagonist protocol
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Infertility, Polycystic Ovaries
Invitro Maturation of Oocytes for Patients With Polycystic Ovaries
In vitro maturation of oocytes after minimal gonadotropin stimulation in patients with polycystic ovaries, to prevent cases of ovarian hyperstimulation.
- Trial name
- NCT00631982
- Testing
- in vitro matuartion of oocytes
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Effect of Hyperandrogenism on IVF Outcomes in PCOS Patients
Ovulatory dysfunction affects 18 to 25% of infertile women, the most common identifiable condition is polycystic ovarian syndrome (PCOS).
- Trial name
- HIP (NCT05555680)
- Testing
- Ferriman-Gallwey Score
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Clinique Ovo
Polycystic Ovary Syndrome
Prevalence of Polycystic Ovary Syndrome In Trinidad
According to World Health Organization (WHO), in 2010, Polycystic Ovarian Syndrome (PCOS) affected approximately 116 million women worldwide (3.4% of the population).
- Trial name
- NCT05937360
- Testing
- cross-sectional community based study
- Where
- Trinidad and Tobago
- Volunteers
- 300 people
- Sponsor
- The University of The West Indies
Pregnancy Complications, Delivery Complications
CoPPer Study - Complications of Polycystic Ovary Syndrome (PCOS) Pregnancy: Evaluating Risk
The CoPPer study is a follow-up study of women diagnosed with Polycystic Ovary Syndrome (PCOS). Women will be included pre-conceptional and followed-up until after delivery.
- Conditions
- Pregnancy Complications, Delivery Complications, Neonatal Complications
- Trial name
- CoPPer (NCT00821379)
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- UMC Utrecht
PCOS, Insulin Resistance
Effects of Simvastatin and Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age. Hyperandrogenism is the central feature of PCOS.
- Trial name
- NCT02766803
- Testing
- Simvastatin and micronized trans-resveratrol
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
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