Clinical trials: Polycystic Ovary Syndrome
PCOS (Polycystic Ovary Syndrome)
Effect of Omega-3 Supplementation as Add on Therapy on Metabolic Syndrome in Women With Polycystic Ovary Syndrome.
The goal of this clinical trial is to learn if Omega-3 works to treat Polycystic ovary syndrome in women. It will also learn about the safety of drug Omega-3.
- Trial name
- NCT07036952
- Testing
- Omega 3 fatty acids, Omega -3 fatty acids
- Where
- Bangladesh
- Volunteers
- 68 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Polycystic Ovarian Syndrome, Weight Loss
Comparison of Intermittent Fasting and Caloric Deficit for Weight Loss in Women With Polycystic Ovarian Syndrome
Time restricted feeding (TRF) has been emerging as a potential weight loss strategy that avoids major dietary changes but achieves strong effects. It also improves insulin sensitivity through increased human growth hormone.
- Conditions
- Polycystic Ovarian Syndrome, Weight Loss, Intermittent Fasting
- Trial name
- NCT04452968
- Testing
- intermittent fasting, Caloric restriction
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Karachi Medical and Dental College
Polycystic Ovary Syndrome, Infertility
Treatment of Infertility in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting up to 10% of women. The primary symptoms of PCOS are menstrual irregularities, increased body and facial hair, acne, and infertility.
- Conditions
- Polycystic Ovary Syndrome, Infertility, Pregnancy
- Trial name
- NCT00068861
- Testing
- metformin XR, clomiphene citrate
- Where
- 11 sites in United States
- Volunteers
- 678 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Polycystic Ovary Syndrome (PCOS)
Mood and Nutrition Interventions in Polycystic Ovary Syndrome
The purpose of this study is to help determine the best treatment plan for women with PCOS who are overweight or obese and experiencing significant symptoms of depression and anxiety.
- Trial name
- MANI-PCOS (NCT01899001)
- Testing
- Cognitive Behavioral Therapy, Nutrition Counseling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pennsylvania
Polycystic Ovary Syndrome, Infertility, Female
Micronutrient Supplementation in PCO-syndrome
The role of micronutrients in fertility has recently gained increased attention. In women who suffer from polycystic ovary syndrome (PCOS) and infertility, we aim to test the impact of a standardized, multinutrient…
- Conditions
- Polycystic Ovary Syndrome, Infertility, Female, Micronutrient Deficiency
- Trial name
- NCT03306745
- Testing
- Profertil female, Folic acid 400 mg
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
PCOS
IVM Versus Standard IVF in Infertile Patients Diagnosed With PCOS
A single center, prospective, open-label, non-inferiority randomized controlled clinical trials (1:1 treatment ratio) regarding pregnancy outcomes between IVM and standard IVF among infertility couples with PCOS in China.
- Trial name
- NCT03463772
- Testing
- standard IVF, In vitro maturation
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Jie Qiao
Infertility, Female
Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome
Polycystic ovary syndrome accounts for the vast majority of anovulatory symptoms and hyperandrogenism in women. The diagnosis of Polycystic ovary syndrome has life-long implications, with increased risk for infertility, metabolic…
- Trial name
- NCT03135301
- Testing
- letrozole plus metformin, letrozole
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Polycystic Ovary Syndrome
The Effect of Lifestyle Program Women With PCOS
Polycystic Ovary Syndrome (PCOS) is a common hormonal condition affecting women of reproductive age. In addition to physical symptoms such as irregular menstruation, hormonal changes, and changes in body weight, women with PCOS…
- Trial name
- PCOS (NCT07880366)
- Testing
- Lifestyle Modification Program (LMP)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Polycystic Ovarian Syndrome, Subfertility
A Comparison of Letrozole and Clomifene Citrate
Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies, affecting 5% to 10% of women of reproductive age. Women with PCOS suffer from anovulatory infertility.
- Trial name
- NCT02647424
- Testing
- Letrozole, Clomiphene
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Polycystic Ovary Syndrome
Effects of Flutamide on Insulin and Glucose Metabolism in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is the major cause of infertility in the United States. Many women with PCOS demonstrate insulin resistance and a compensatory hyperinsulinemia.This is due to both an intrinsic form of insulin…
- Trial name
- PCOS (NCT00729560)
- Testing
- Flutamide
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Virginia Commonwealth University
Obstructive Sleep Apnea Syndrome, Polycystic Ovary Syndrome
Effect of Obstructive Sleep Apnea Syndrome on Insulin Sensitivity and Cardiovascular Risk in PCOS Adolescents
Polycystic ovary syndrome (PCOS) is one of the most common disease caused by hormonal imbalance and is also associated with overweight and obesity. It affects 5-10% of adolescent girls and women capable of having children.
- Conditions
- Obstructive Sleep Apnea Syndrome, Polycystic Ovary Syndrome, Sleep Apnea
- Trial name
- NCT01840618
- Testing
- Nasal Continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Infertility, Poly Cystic Ovary Syndrome
The Effectiveness of CPII for Infertility Induced by PCOS in China
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age and is associated with metabolic, reproductive and mental health complications.
- Trial name
- CPII-PCOS-I (NCT07906756)
- Testing
- Standard Treatment for PCOS-Induced Infertility, Counselling-Integrated Standard Care for PCOS-Induced Infertility, Personalized Care-Integrated Intervention (PII)
- Where
- 4 sites in China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Polycystic Ovary Syndrome, Infertility
Graceful Lifestyle Changes Study for PCOS and Infertility
The purpose of this study is to help women with PCOS to improve their symptoms and ovulation rate through a lifestyle intervention program which introduces a specific diet, a physical activity regimen and mindfulness exercises to…
- Trial name
- GLC (NCT02630485)
- Testing
- Graceful Lifestyle Changes, Myo-inositol, Letrozole
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Polycystic Ovary Syndrome
Clinical、metabolomics and the Study of Intestinal Flora of Jinfeng Pills in the Treatment of Polycystic Ovary Syndrome
The goal of this clinical trial is to compare the clinical effect of Jinfeng Pill and Diane-35 in patients with PCOS. The main questions it aims to answer are: a.
- Trial name
- NCT06823830
- Testing
- Jinfeng Pill
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Peking Union Medical College Hospital
Polycystic Ovary Syndrome, Gingivitis
Evaluation of the Effect of Non-Surgical Periodontal Treatment in Women With Polycystic Ovary Syndrome
The goal of this clinical trial is to compare women with polycystic ovary syndrome and systemically healthy woman in relation to their gums and gum treatment outcomes as well as to investigate the role of a new biomarker in gum…
- Trial name
- NCT06567132
- Testing
- Non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Polycystic Ovary Syndrome
Effect of Exercise on Cardiometabolic Profile in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a complex hormonal and metabolic disorder that has been shown to affect women's fertility. It can also share many symptoms with pre-diabetes, and women with PCOS often have an increased risk…
- Trial name
- NCT03678714
- Testing
- Exercise Intervention, Lifestyle Physical Activity
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Sheffield Hallam University
Polycystic Ovary Syndrome, L-arginine
The Role of L-arginine in Polycystic Ovary Syndrome
PCOS patients meeting the trial criteria were enrolled from the Shanghai 10th People's Hospital. The contents of this study were introduced to them, and they were invited to participate in the study.
- Conditions
- Polycystic Ovary Syndrome, L-arginine, Gut Microbiome
- Trial name
- NCT06728644
- Testing
- L-arginine intervention
- Where
- 2 sites in China
- Volunteers
- 31 people
- Sponsor
- Shanghai 10th People's Hospital
Polycystic Ovary Syndrome
Metformin Treatment Before in Vitro Fertilization (IVF) in Women With Ultrasound Evidence of Polycystic Ovaries
The aim of study was to investigate whether pre-treatment with metformin before and during IVF increases the live birth rate compared to placebo in women with sonographic evidence of polycystic ovaries (PCO), but without any…
- Trial name
- NCT01046032
- Testing
- Metformin
- Where
- 3 sites in United Kingdom
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Polycystic Ovary Syndrome
Weight Cycling on Hyperandrogenemia and Insulin Resistance in Polycystic Ovary Syndrome
This study prospectively includes PCOS patients with normal weight and overweight/obesity, closely follows up and intensively manages them, and observes the level and distribution of weight reduction achieved by patients after…
- Trial name
- WHIP (NCT06545721)
- Testing
- Adjusting dietary structure + exercise + behavioral intervention, Precision dietary prescription, Standard guideline-based low-energy diet
- Where
- China
- Volunteers
- 425 people
- Sponsor
- Peking Union Medical College Hospital
PCOS (Polycystic Ovary Syndrome)
The Aim of This Study is to Gain Insight Into the Occurrence of Irritable Bowel Symptoms During Ovarian Stimulation in Individuals With PCOS and in Women Who Wish to Freeze Their Eggs. This Study Uses Questionnaires.
This exploratory study investigates the impact of fertility treatments on symptoms of irritable bowel syndrome (IBS) in women. Specifically, the study focuses on two groups: Women with polycystic ovary syndrome (PCOS) who are…
- Trial name
- FIBS (NCT07533968)
- Testing
- questionnaires
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
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