Clinical trials: Polycystic Ovary Syndrome (PCOS)
PCOS (Polycystic Ovary Syndrome)
Development and Clinical Application of ApoC3 Protein as a Predictive Biomarker for Insulin Resistance in Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is the most common reproductive endocrine disorder causing infertility and miscarriage in women.
- Trial name
- NCT07739953
- Testing
- observational study
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Polycystic Ovary Syndrome, Insulin Resistance
Auricular Acupressure (AA) For Insulin Resistance in Women With Polycystic Ovary Syndrome
The present trial is a pilot study to investigate the effect of auricular acupressure on insulin resistance in women with PCOS.A total of 100 subjects will be enrolled into this study and will be randomized into two groups.
- Trial name
- NCT03546595
- Testing
- Auricular acupoints acupressure
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Heilongjiang University of Chinese Medicine
PCOS (Polycystic Ovary Syndrome)
Efficacy of a GLP-1/FGF21 Dual Agonist for Treating PCOS
Polycystic ovary syndrome (PCOS) is the most common reproductive endocrine and metabolic disorder among women of reproductive age.
- Trial name
- NCT07616037
- Testing
- GLP-1/FGF21 dual agonist (HEC88473)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Zhongshan Hospital
PCOS
Cavitation Ultrasound in Treatment of Patients With PCOS
The aim of the current work was to compare the efficacy of cavitation ultrasound, metformin or combination of both in obese women with polycystic ovary syndrome (PCOS) regarding clinical pregnancy rate, ovulation rate, insulin…
- Trial name
- NCT01622257
- Testing
- Cavitation US, Metformin, Cavitation US + Metformin
- Where
- Egypt
- Volunteers
- 198 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome, Dry Eye
PCOS and Problem of Eye Dryness: Is There a Benefit From Lifetyle Changes
Women with polycystic ovarian syndrome (PCOS) may complain dryness of their eyes especially obese ones. lifestye changes are main treatrment fro both problems
- Conditions
- Polycystic Ovary Syndrome, Dry Eye, Obesity
- Trial name
- NCT07366944
- Testing
- exercise and limiting diet, diet limitation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Insulin Sensitivity, Polycystic Ovarian Syndrome
Assessment of Cod Protein as an Insulin-sensitizing Agent in Women With Polycystic Ovary Syndrome.
The objective of our study is to determine the effects of fish protein on insulin sensitivity in PCOS women with insulin resistance, and its mechanism of action on glucose and endocrine metabolism.
- Trial name
- PCOS (NCT01766557)
- Testing
- Semi-controlled nutritional intervention with fish protein diet, Semi-controlled intervention with other animal proteins
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Laval University
Polycystic Ovary Syndrome
Effect of Ultrasound Cavitation Versus Electrolipolysis on Obese Infertile Women With Polycystic Ovarian Syndrome
This study aims to determine the difference between the effect of ultrasound cavitation and electrolipolysis on obese infertile women with polycystic ovarian syndrome.
- Trial name
- NCT06490419
- Testing
- Electrolipolysis, ultrasound cavitation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
PCOS
Effect of Chromium Supplementation on Intracytoplasmatic Sperm Injection (ICSI) Outcomes in Polycystic Ovary Syndrome Ladies
This study is a prospective, double-blind, randomized controlled trial . It included 60 infertile obese patients with polycystic ovary syndrome (PCOS), who are scheduled for intracytoplasmatic sperm injection (ICSI) cycle.
- Trial name
- NCT03503201
- Testing
- Chromium
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kasr El Aini Hospital
Polycystic Ovary Syndrome (PCOS)
Effect of a Digital Health Education Program on Quality of Life in Women With Polycystic Ovary Syndrome
This single-blind randomized controlled trial evaluated the effectiveness of a digital health education program delivered through WhatsApp in improving the quality of life of women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT07684430
- Testing
- Digital Health Education Program, routine care
- Where
- Cyprus
- Volunteers
- 70 people
- Sponsor
- Near East University, Turkey
Type 1 Diabetes Mellitus, Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome in Type 1 Diabetes
BACKGROUND Functional ovarian hyperandrogenism, including the polycystic ovary syndrome (PCOS), is very prevalent in women with type 1 diabetes (T1D). The pathogenic mechanisms of this association remain unclear.
- Trial name
- NCT07490964
- Testing
- Type 1 diabetes mellitus, Elevated circulating androgen levels, Sex dimorphism
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Polycystic Ovarian Syndrome (PCOS)
Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study
In polycystic ovary syndrome (PCOS), changes in physical appearance i.e. weight gain, hirsutism, menstrual disturbances and infertility result in reduced quality-of-life.
- Trial name
- NCT07459595
- Testing
- Myoinositol, Metformin
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Fatima Tariq
Polycystic Ovary Syndrome, Overweight
Clinical Sciences Research Proposal- The Effect of Physical Exercise on PCOS Overweight Female Adolescents
The Poly Cystic Ovary Syndrome (PCOS), is one of the most common reasons for subfertility, oligomenorrhea and amenorrhea. With the occurrence of 6-20% of the general adult women population.
- Trial name
- NCT03068221
- Testing
- anaerobic exercise
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Polycystic Ovary Syndrome
Reflexology's Effect on Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome (PCOS) is very common, affecting approximately 5% of women of reproductive age, and impacts not only on quality of life, but also has long-term health consequences for many sufferers, such as increased…
- Trial name
- REPOS (NCT00744510)
- Testing
- Reflexology
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- University of Nottingham
Polycystic Ovary Syndrome, Diet Habit
The Results of the Mediterranean Diet for PCOS
The aim was to evaluate the effects of the application of a Mediterranean diet on the reproductive and metabolic parameters in the 3rd month in patients with a body mass index of 25 and more who were followed up in our clinic due…
- Trial name
- PCOS (NCT06442189)
- Testing
- Mediterranean Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Polycystic Ovarian Syndrome, Ovarian Hyperstimulation Syndrome
Long Acting GnRH Antagonist in PCOS Women Undergoing IVF
PCOS is a common endocrinopathy affecting 5-10% of women in their reproductive age characterized by hyperandrogenism, chronic anovulation and polycystic ovaries.
- Conditions
- Polycystic Ovarian Syndrome, Ovarian Hyperstimulation Syndrome, Invitro Fertilization
- Trial name
- NCT02084940
- Testing
- GnRH antagonist depot Degarelix
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bioroma
Polycystic Ovarian Syndrome
Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome
Objective: 1. To investigate the changes in the levels of interleukin-6 and interleukin-8 after 3 months treatment with metformin alone and combination of metformin and pioglitazone in patients with polycystic ovarian syndrome…
- Trial name
- NCT03117517
- Testing
- Metformin, Metformin, Pioglitazone
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- Khyber Medical University Peshawar
Polycystic Ovary Syndrome
Improving Reproductive Function in Women With Polycystic Ovary Syndrome by High Intensity Interval Training
The aim is to investigate whether 16 weeks of high intensity interval training, followed by 36 weeks of home-based exercise, will improve menstrual frequency in women with Polycystic Ovary Syndrome (PCOS) compared with a…
- Trial name
- IMPROV-IT (NCT02419482)
- Testing
- 4x4 minutes high intensity interval training, 10x1 minute high intensity interval training
- Where
- 2 sites in Australia, Norway
- Volunteers
- 64 people
- Sponsor
- Norwegian University of Science and Technology
Polycystic Ovary Syndrome
Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S
This study will be carried out in an attempt to know which is more effective, Intermittent fasting diet or resistive exercise program on insulin resistance in obese woman with polycystic ovarian syndrome.
- Trial name
- NCT06882291
- Testing
- Intermittent fasting diet, Resistive exercise program, Medical treatment
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety
Online Brief CBT Intervention for Women With PCOS
Primary Objective: -To study if an online individual brief CBT (group A) intervention is effective for psychological distress (anxiety and depression) compared to a CAU group in patients with PCOS at 3 and 6 months relative to…
- Conditions
- PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety, Self Esteem
- Trial name
- How2deal (NCT05679362)
- Testing
- online brief CBT intervention
- Where
- Netherlands
- Volunteers
- 222 people
- Sponsor
- Erasmus Medical Center
Type2 Diabetes, Polycystic Ovary Syndrome
Myocardial Pathological Changes in Patients of Type 2 Diabetes With or Without PCOS Using Cardiac Magnetic Resonance
The study is prepared to use CMR technology for early screening of myocardial lesions in 561 age-matched women with type 2 diabetes without PCOS, with PCOS without type 2 diabetes and with type 2 diabetes combined with PCOS…
- Trial name
- NCT04805853
- Where
- China
- Volunteers
- 561 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
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