Clinical trials: Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome, Cardiovascular Disease
LIPT - Liraglutide in Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) affects 5-10% of women in fertile age. PCOS is associated with metabolic syndrom, diabetes and and increased risk og cardiovascular disease.
- Trial name
- LIPT (NCT02073929)
- Testing
- Liraglutide for 26 weeks
- Where
- 3 sites in Denmark
- Volunteers
- 72 people
- Sponsor
- Jens Faber
Polycystic Ovary Syndrome
Molecular Basis of PCOS in Oocytes and Surrounding Cells
Polycystic ovary syndrome (PCOS) is a common disorder in women of reproductive age that is characterized by elevated androgen levels, ovulatory dysfunction and polycystic ovarian morphology (PCOM).
- Trial name
- NCT04493788
- Testing
- Blood test, ultrasound and egg retrieval
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
PCOS, NAFLD
Androgens and NAFLD Longitudinal Cohort Study
The researchers want to learn how androgens, a type of sex hormone, might affect nonalcoholic fatty liver (NAFLD) in young women over time.
- Conditions
- PCOS, NAFLD, NASH
- Trial name
- NCT06124261
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
Polycystic Ovary Syndrome, In Vitro Fertilization
Polycystic Ovary Syndrome (PCOS) and In Vitro Fertilization (IVF): A Comparison Between Standard Long Protocol Versus an Antagonist Protocol Starting on Day 1
The aim of this study is to compare two different IVF-stimulation protocols in patients affected by PCOS: the use of a Gonadotropin-releasing hormone (GnRH) - antagonist starting on day 1 of controlled ovarian hyperstimulation…
- Trial name
- NCT00883766
- Testing
- Controlled ovarian hyperstimulation for IVF with a long agonist protocol, Controlled ovarian hyperstimulation for IVF with an antagonist protocol
- Where
- Spain
- Volunteers
- 172 people
- Sponsor
- Fundacion Dexeus
Polycystic Ovary Syndrome
Serum Anti-Mullerian Hormone (AMH) Levels in Overweight and Obese Adolescent Girls With Polycystic Ovaries
In this study the investigators aimed to investigate whether there is a relation between body weight and serum anti mullerian hormone levels in adults with polycystic ovary syndrome.
- Trial name
- NCT01856894
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Polycystic Ovary Syndrome (PCOS)
MLE4901 vs. Placebo for the Treatment of PCOS
This is a Phase 2b double-blind, randomized, parallel-group, placebo-controlled study of MLE4901 versus placebo in women with PCOS.
- Trial name
- NCT02865915
- Testing
- MLE4901
- Where
- 31 sites in United States
- Volunteers
- 55 people
- Sponsor
- Millendo Therapeutics US, Inc.
Polycystic Ovary Syndrome
Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET)
The investigator's global hypothesis is that women with Polycystic Ovary Syndrome (PCOS) can be separated into subtypes based on their response to metformin.
- Trial name
- NCT02086526
- Testing
- Metformin
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Mayo Clinic
Polycystic Ovary Syndrome
PCOSMIC Trial - PolyCystic Ovary Syndrome, Metformin for Infertility With Clomiphene
1. Metformin increases the pregnancy rate when added to the standard treatment of anovulatory polycystic ovary syndrome (PCOS). 2.
- Trial name
- PCOSMIC (NCT00795808)
- Testing
- Metformin, Metformin + Clomiphene, Clomiphene
- Where
- New Zealand
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Polycystic Ovary Syndrome, Anovulation
Short-term Structured Exercise Training Program Plus Diet Intervention in Patients With Polycystic Ovary Syndrome (PCOS)
Clomiphene citrate (CC) is the first-line therapy for infertile women with polycystic ovary syndrome (PCOS). Unfortunately, at least 20% of PCOS results are not responsive to CC.
- Trial name
- NCT01004068
- Testing
- SET-diet plus clomiphene, Clomiphene citrate, Structured exercise program plus hypocaloric diet
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- University Magna Graecia
Polycystic Ovary Syndrome, Diabetes, Gestational
Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome
Randomized, placebo controlled clinical trial that evaluate the role of taking metformin therapy during pregnancy in women with polycystic ovarian syndrome(PCOS) in reducing the development of gestational diabetes(GDM) and…
- Trial name
- MGDPCOS (NCT02802215)
- Testing
- metformin
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome
Laparoscopic Ovarian Drilling and Subendometrial Blood Flow
Serum level of total testosterone was measured in the early follicular phase (days 2-4 of spontaneous cycle in oligomenorrhic patients).
- Trial name
- PCOS (NCT03334955)
- Testing
- Laparoscopic ovarian drilling
- Volunteers
- 200 people
- Sponsor
- Zagazig University
Polycystic Ovary Syndrome
Treating Obese PCOS Patients With LSG vs. Met
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to 15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation disorders and/or hyperandrogenemia, and often…
- Trial name
- NCT04508634
- Testing
- laparoscopic sleeve gastrectomy, Metformin Pill
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai 10th People's Hospital
Polycystic Ovary Syndrome, Overweight
Clinical Sciences Research Proposal- The Effect of Physical Exercise on PCOS Overweight Female Adolescents
The Poly Cystic Ovary Syndrome (PCOS), is one of the most common reasons for subfertility, oligomenorrhea and amenorrhea. With the occurrence of 6-20% of the general adult women population.
- Trial name
- NCT03068221
- Testing
- anaerobic exercise
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Polycystic Ovary Syndrome, Obesity
Correlating Improvement in PCOS Symptoms to the Percentage of Body Weight Lost in Females Also Living With Obesity
The goal of this clinical trial is to study the effects of a intensive weight loss program (STREAM) in patients living with PCOS.
- Trial name
- FLOWERS-PCOS (NCT06325449)
- Testing
- STREAM program
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Ottawa Hospital Research Institute
Unexplained Infertility, Polycystic Ovarian Syndrome
Nimodipine to Prevent LH Surge During Ovulation Induction: Blinded Placebo-controlled RCT
The main purpose of this study is to test the effectiveness of nimodipine in preventing a luteinizing hormone (LH) surge in women undergoing ovulation induction with clomiphene citrate.
- Conditions
- Unexplained Infertility, Polycystic Ovarian Syndrome, Anovulatory
- Trial name
- NIMO (NCT01672801)
- Testing
- Nimodipine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Breast Diseases, Polycystic Ovary
Breast Ultrasonography and Polycystic Ovary Syndrome
The results of the evaluation of breast ultrasonography results of patients with polycystic ovary syndrome diagnosis over 30 years of age will be evaluated.
- Trial name
- NCT04231786
- Testing
- Breast ultrasonography findings
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Polycystic Ovary Syndrome
Effect of Dietary Fiber Intervention on Patients With Polycystic Ovary Syndrome
The purpose of the study is to understand the effect of dietary fiber on patients with polycystic ovary syndrome.
- Trial name
- NCT05431816
- Testing
- Dietary intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Polycystic Ovary Syndrome
Role of Melatonin Supplementation in Follicular Fluid of in Vitro Fertilization (IVF) Patients With Polycystic Ovarian Syndrome
To evaluate the effects of melatonin supplementation on the main in vitro fertilization (IVF) outcomes during ovarian stimulation in patients with Polycystic ovarian syndrome (PCOS).
- Trial name
- NCT01540747
- Testing
- Myo-inositol + folic acid + melatonin, Myo-inositol + folic acid
- Where
- Italy
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Polycystic Ovary Syndrome
Vitamin D Status in Relation to Insulin Sensitivity Among Saudi Women With Polycystic Ovary Syndrome
The study tests the hypothesis that correction of vitamin D deficiency among women with PCOS will improve insulin sensitivity and resistance and inflammatory response to PCOS.
- Trial name
- CEOR-04-08 (NCT02164552)
- Testing
- Vitamin D3 pills
- Where
- Saudi Arabia
- Volunteers
- 340 people
- Sponsor
- King Abdulaziz University
Polycystic Ovary Syndrome
Myo-inositol Versus Metformin in Obese Women With Polycystic Ovary Syndrome
The aim of this study is to compare the effects of six months treatment of two insulin-lowering therapies on the clinical and endocrine-metabolic parameters in obese women affected by polycystic ovary syndrome.
- Trial name
- NCT01791647
- Testing
- metformin 1500 mg, myoinositol 1500 mg
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
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