Clinical trials: Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome
Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome
In PCOS (Polycystic Ovary Syndrome), studies have found impaired incretin secretion and activity, particularly in overweight/obese individuals.
- Trial name
- NCT06576375
- Testing
- Dapagliflozin, Metformin
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Future University in Egypt
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Effect of Metformin on Patients With Polycystic Ovary Syndrome
The purpose of the study is to understand the effect of Metformin on patients with PCOS.
- Trial name
- NCT05802212
- Testing
- Metformin intervention for 12 weeks
- Where
- China
- Volunteers
- 77 people
- Sponsor
- Peking University Third Hospital
Reproductive Endocrinology, Polycystic Ovarian Syndrome
Metformin Improves Clinical Pregnancy Rate in Polycystic Ovarian Syndrome Patients
Polycystic ovary syndrome (PCOS) is the most common Female endocrine disorder , with a prevalence ranging between 6% to10% based on the National Institutes of Health (NIH) criteria and when the broader Rotterdam criteria are…
- Trial name
- NCT02562664
- Testing
- CC, Metformin
- Volunteers
- 66 people
- Sponsor
- Assiut University
PCOS, Infertility, Female
Effect of Acupuncture Plus Governor Vessel Moxibustion Combined With Letrozole on Live Birth in Anovulatory Infertile Women With Spleen-kidney Yang Deficiency PCOS
Investigators expected to verify this hypothesis through this study:acupuncture and moxibustion combined with LE induced ovulation in Chinese anovulatory PCOS women has a higher rate of live birth than LE induced ovulation alone.
- Trial name
- PCOS (NCT04987632)
- Testing
- Letrozole, acupuncture, Governor vessel moxibustion
- Volunteers
- 90 people
- Sponsor
- Qiu-ping Lin
Polycystic Ovary Syndrome
Effect of Nicotinic Acid on Cardiovascular Risks Indices in Polycystic Ovary Syndrome
Niacin will improve postprandial hyperlipidaemia and cardiovascular risks indices via its lipid lowering as well as via pleiotropic effects in patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT01118598
- Testing
- tredaptive (nicotinic acid/ laropiprant)
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Polycystic Ovary Syndrome, PCOS
Obstetric Outcomes in Women With PCOS
The aim of the study is to investigate body composition in newborn children of women with PCOS and controls and to investigate adverse obstetric outcomes in pregnant women with PCOS.
- Trial name
- NCT01983202
- Where
- Denmark
- Volunteers
- 1,248 people
- Sponsor
- Odense University Hospital
Polycystic Ovary Syndrome, Ovarian Hyperstimulation Syndrome
The Four Methods of Ovarian Stimulation in Patients With Polycystic Ovarian Syndrome
This study is a randomized controlled clinical trial to compare the pregnancy outcomes of mild and minimal stimulation in infertile women with polycystic ovarian syndrome.
- Trial name
- NCT03876145
- Testing
- Minimal ovarian stimulation
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Polycystic Ovary Syndrome, Anovulatory
Endometrial Thickness and Subendometrial Vascularity in Anovulatory Polycystic Ovarian Syndrome Patients Treated by Metformin
The participants will receive metformin 500mg 3times per day for 3months and one month is left for spontaneous pregnancy to occur or not (primary outcome ) and the investigators will check endometrial thickness and…
- Trial name
- NCT03486626
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Ain Shams Maternity Hospital
PCOS (Polycystic Ovary Syndrome)
Impact of Myo-Inositol Alone vs Myo-Inositol Plus Metformin on Conception, Adherence, and Tolerability in PCOS
The goal of this clinical trial (prospective randomized controlled trial) is to compare whether myo-inositol alone or in combination with metformin can improve conception rates, treatment compliance, and side-effect profiles in…
- Trial name
- NCT07323589
- Testing
- Myoinositol, Metformin 1500 mg daily
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- PAEC general hospital
Polycystic Ovarian Syndrome, Ovarian Hyperstimulation Syndrome
Long Acting GnRH Antagonist in PCOS Women Undergoing IVF
PCOS is a common endocrinopathy affecting 5-10% of women in their reproductive age characterized by hyperandrogenism, chronic anovulation and polycystic ovaries.
- Conditions
- Polycystic Ovarian Syndrome, Ovarian Hyperstimulation Syndrome, Invitro Fertilization
- Trial name
- NCT02084940
- Testing
- GnRH antagonist depot Degarelix
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Bioroma
PCOS
Changes in Hormonal Profile and Body Mass Index in Women With Polycystic Ovary Syndrome After Probiotic Intake
Changes in hormonal profile and body mass index in women with polycystic ovary syndrome were analised after probiotic intake.
- Trial name
- NCT06761625
- Testing
- SanProbi® Barrier capsules
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Pomeranian Medical University Szczecin
Polycystic Ovary Syndrome
Multi-omics Analysis of Women With PCOS and Obesity Compared With Non-PCOS Obese Controls
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in reproductive-aged women， which associated with increased risks to develop metabolic disorders, including cardiovascular diseases, diabetes mellitus…
- Trial name
- NCT05468476
- Testing
- No intervention
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Zhang Manna
Polycystic Ovary Syndrome
Evaluation of Endocrine and Metabolic Parameters in the New Diagnostic Phenotypes of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a very frequent endocrine disease of women in reproductive age, with an estimated prevalence of 5 to 10 % according to the studied population.
- Trial name
- NCT00784615
- Testing
- Blood samples, transvaginal ultrasound
- Where
- Argentina
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Córdoba
Polycystic Ovary Syndrome
Surgical Ovarian Drilling Versus Hormonal Treatment for Infertility Associated to PolyCystic Ovaries Syndrome (PCOS)
PolysCsytic Ovaries Syndrome (PCOS) is the most frequent endocrinopathy. The first stage of infertility treatment is Clomiphene Citrate which leads to 50 % pregnancies.
- Trial name
- PERCING (NCT00378729)
- Testing
- Metformin and FSHr, Ovarian drilling by FERTILOSCOPY
- Where
- France
- Volunteers
- 252 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Polycystic Ovary Syndrome, Insulin Resistance
Auricular Acupressure (AA) For Insulin Resistance in Women With Polycystic Ovary Syndrome
The present trial is a pilot study to investigate the effect of auricular acupressure on insulin resistance in women with PCOS.A total of 100 subjects will be enrolled into this study and will be randomized into two groups.
- Trial name
- NCT03546595
- Testing
- Auricular acupoints acupressure
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Polycystic Ovary Syndrome
Oral Administration of DCI to Women With PCOS
To determine if oral DCI administration to women with PCOS increases the total DCI content in urine and blood, and, if so, if that change is accompanied by i) an increase in DCI-IPG release in blood (as determined by bioactivity)…
- Trial name
- PCOS (NCT00497653)
- Testing
- DCI
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Virginia Commonwealth University
Polycystic Ovary Syndrome
The Relationship of PRL and Polycystic Ovary Syndrome (PCOS) in Taiwan's Women
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder of reproductive-age women. According to Rotterdam 2003 criteria: at least two of three criteria are met, hyperandrogenism, chronic anovulation, and…
- Trial name
- NCT01117272
- Where
- Taiwan
- Volunteers
- 474 people
- Sponsor
- Taipei Medical University WanFang Hospital
Polycystic Ovary Syndrome
Environmental Factors in the Development of Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is manifested as a heterogeneous mixture of clinical and bichemical characteristics that complicate study of its etiology.
- Trial name
- NCT00341731
- Where
- 2 sites in United States
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Adverse Effect of Oral Contraceptives, Sequela
Contraceptive Pill and Hormonal Vaginal Ring in Women With Polycystic Ovary Syndrome
The main aims of this study are: to investigate and compare the effects of long lasting use (59 weeks) of vaginal and oral contraceptives on androgen secretion, insulin and glucose metabolism, lipid profile, and serum levels of…
- Trial name
- NCT01588873
- Testing
- oc:E-E-desogestrel/vaginal ring:E-E -ethonogestrel
- Where
- Finland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Anovulation, Polycystic Ovary Syndrome
Circulating Androgen Levels Are Not Affected by the Administration of Vaginal Micronized Progesterone for Withdrawal Bleeding in Patients With Polycystic Ovarian Syndrome
Hormonal evaluation of women who are suspected of having Polycystic ovary syndrome (PCOS) involves the measurement of basal levels of androgens and 17-hydroxyprogesterone (17-OHP), which are generally used to establish the…
- Conditions
- Anovulation, Polycystic Ovary Syndrome, Hyperandrogenism
- Trial name
- NCT03088046
- Testing
- Micronized Progesterone
- Volunteers
- 15 people
- Sponsor
- Fundacion Dexeus
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