Clinical trials: Polycystic Ovary Syndrome (PCOS)
Polycystic Ovarian Syndrome (PCOS), Patients Sensitive to Exogenous Gonadotropins
In Vitro Maturation (IVM) of Human Oocytes
We hypothesize that the combination of natural cycle IVF or low dose gonadotropin injection combined with In Vitro Maturation (IVM) (Natural IVF/IVM) is a viable option for a selected population of infertility patients who cannot…
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Patients Sensitive to Exogenous Gonadotropins, Ovarian Hyper Stimulation Syndrome (OHSS)
- Trial name
- IVM (NCT01843569)
- Testing
- In Vitro maturation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Polycystic Ovary Syndrome
Incretin Effect in PCOS Women
This study investigates the incretin effect in women with polycystic ovary syndrome (PCOS) before and after removal of their insulin resistance by metformin.
- Trial name
- NCT01892254
- Testing
- Metformin
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
PCOS (Polycystic Ovary Syndrome)
Effect of Drospirenone-Ethinyl Estradiol (20microgram vs 30 Microgram) on Free Androgen Index in PCOS
Combined hormonal contraceptive (CHC) improves androgen parameter in women with PCOS. High-dose CHC increases insulin resistance, whereas low dose CHC has minimal effects on carbohydrate metabolism.
- Trial name
- PCOS FAI CHC (NCT07318337)
- Testing
- Drospirenone Ethinyl Estradiol (20 microgram), Drospirenone Ethinyl Estradiol (30 microgram)
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Mst.Sumyara Khatun
PCOS
A Metabolomic Study of Polycystic Ovary Syndrome With Insulin Resistance and Its Relationship With TCM Syndrome Types
The type-2 diabetes mellitus（T2DM）, metabolic syndrome, cardiovascular disease complications induced by polycystic ovary syndrome(PCOS) with insulin resistance(IR）, which become serious threat to public health.
- Trial name
- NCT02992093
- Testing
- all the indicators
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fujian Maternity and Child Health Hospital
Polycystic Ovarian Syndrome, Insulin Resistance
LNK in Polycystic Ovary Syndrome With Insulin Resistance
Insulin resistance (IR) is an important pathological feature of polycystic ovary syndrome (PCOS), with an incidence rate of up to 85%, which seriously affects the patient's fertility, quality of life, and offspring health, but…
- Trial name
- NCT05146063
- Testing
- Take the patient's subcutaneous fat tissue to detect the expression of LNK
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Polycystic Ovary Syndrome, Dietary Habits
Comparison of Lifestyle Markers Between Women With and Without Polycystic Ovary Syndrome
The purpose of the study is to identify lifestyle factors associated with PCOS and understand how diet and activity levels impact features of PCOS.
- Conditions
- Polycystic Ovary Syndrome, Dietary Habits, Physical Activity
- Trial name
- NCT01859663
- Where
- 3 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Cornell University
Type 1 Diabetes Mellitus, Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome in Type 1 Diabetes
BACKGROUND Functional ovarian hyperandrogenism, including the polycystic ovary syndrome (PCOS), is very prevalent in women with type 1 diabetes (T1D). The pathogenic mechanisms of this association remain unclear.
- Trial name
- NCT07490964
- Testing
- Type 1 diabetes mellitus, Elevated circulating androgen levels, Sex dimorphism
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Periodontal Diseases
"Effect of CPA/EE Drug on Periodontal Tissue and hsCRP Levels in PCOS Patients With Gingivitis
PCOS is a widely reported condition among young female population and anti-androgen agents are increasingly being used as part of the medical management of such cases.
- Trial name
- NCT05657171
- Testing
- cyproterone Acetate/Ethinyl Estradiol Combination
- Where
- India
- Volunteers
- 47 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Polycystic Ovary Syndrome, Insulin Resistance
Acupuncture to Treat Insulin Resistance in Women With and Without Polycystic Ovary Syndrome
The central hypothesis is that acupuncture break the vicious circle of androgen excess and reverse insulin resistance and improve health related quality of life and affective symptoms in overweight and obese women with and…
- Trial name
- PCOS-AcupIR (NCT01457209)
- Testing
- Acupuncture
- Where
- Sweden
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Polycystic Ovary Syndrome
Ovarian Morphology and Theca Cell Androgen Production in Women With Polycystic Ovary Syndrome (PCOS)
Women with PCOS suffer from excess male hormone (androgen) production by the ovary. Androgen is made by cells that surround follicles that contain eggs.
- Trial name
- NCT02145247
- Testing
- hCG
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Polycystic Ovary Syndrome, Obesity
Time Restricted Eating for the Treatment of PCOS
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility among young women. This syndrome is a reproductive and endocrinological disorder that affects up to 18% of reproductive-aged women.
- Conditions
- Polycystic Ovary Syndrome, Obesity, Overweight
- Trial name
- NCT05629858
- Testing
- 6-h Time restricted eating (TRE), Calorie restriction (CR), Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
PCOS (Polycystic Ovary Syndrome), Cumulus Cell
Transcriptomic Profiling of Cumulus Cells From CAPA-IVM
Capacitation in vitro maturation (CAPA-IVM) has improved oocyte maturation and resulted in live births. Because cumulus cells (CCs) communicate bidirectionally with the oocyte, their transcriptomic profile may serve as a…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Cumulus Cell, Capacitation IVM, Transcriptomic Profiling
- Trial name
- NCT07197255
- Where
- Vietnam
- Volunteers
- 10 people
- Sponsor
- Mỹ Đức Hospital
Polycystic Ovary Syndrome
Effect of Aerobic Exercise on Polycystic Ovary Syndrome
The development of Polycystic Ovary Syndrome has been linked to chronic low-grade inflammation (PCOS). In this context, the current study looked into the effects of aerobic exercise on IL6, TNF, and C-reactive protein (CRP) in…
- Trial name
- NCT05233514
- Testing
- Aerobic exercise in addition to Metformin treatment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
Effect of Laser Acupuncture on Insulin Resistance in Obese Women With Polycystic Ovarian Syndrome
This study will be conducted to investigate the effect of laser acupuncture on insulin resistance in obese women with polycystic ovarian syndrome.
- Trial name
- NCT06549647
- Testing
- low caloric diet, Laser Acupuncture
- Volunteers
- 40 people
- Sponsor
- Cairo University
Treatment Resistant Disorders
Adding L-carnitine in Clomiphene Resistant Polycystic Ovary Improves the Quality of Ovulation and the Pregnancy Outcome
Adding L-carnitine is more successful than clomiphene as a first line therapy for ovulation induction in women with clomiphene resistant PCOS
- Trial name
- NCT01665547
- Testing
- l-carnitine
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Polycystic Ovary Syndrome
Efficacy of Metformin in Lean Women With Polycystic Ovary Syndrome
Insulin resistance is an important feature of the polycystic ovary syndrome,and patiens are successfully treated with the insulin sensitizing agent metformin. The insulin resistance of lean patients with the syndrome is debated.
- Trial name
- NCT00319293
- Testing
- Metformin
- Volunteers
- 20 people
- Sponsor
- Aarhus University Hospital Skejby
Polycystic Ovary Syndrome (PCOS)
Efficacy of Empagliflozin or Linagliptin as an Alternative to Metformin for Treatment of Polycystic Ovary Syndrome
The study aims to compare the efficacy of Empagliflozin or Linagliptin as an alternative to Metformin for treatment of non-diabetic patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT05200793
- Testing
- Empagliflozin 25 mg, Linagliptin 10 mg, Metformin 1500 mg
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Alexandria University
Polycystic Ovary Syndrome, Insulin Resistance
Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls
The goal of this interventional study is to assess the effect of drug metformin in improving the fertility hormones and reducing the inflammatory hormones in polycystic ovarian syndrome (PCOS) patients.
- Trial name
- NCT06479434
- Testing
- Metformin
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Polycystic Ovary Syndrome
Treatment of Adolescent Polycystic Ovary Syndrome (PCOS)
A 24 week study to compare the use of Metformin, birth control pills and a carefully planned intensive lifestyle program that includes weight loss and exercise.
- Trial name
- NCT00714233
- Testing
- Metformin, Oral Contraceptive Pills (Yasmin), Lifestyle Modification
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Polycystic Ovary Syndrome
PCOS Indirect and Intangible Economic Burden
The primary purpose of the PCOS Indirect and Intangible Economic Buren study is to estimate the economic costs of having PCOS in terms of quality of life and work productivity.
- Trial name
- PCOSCHALLENGE (NCT05903404)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- PCOS Challenge: The National Polycystic Ovary Syndrome Association
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.