Clinical trials: Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome
Controlled Ovarian Stimulation Followed by Timed Intercourse or Intrauterine Insemination in Infertile PCOS Patients
At the present the first options to induce ovulation in polycystic ovary syndrome with anovulatory infertility are clomiphene citrate (CC) and metformin.
- Trial name
- NCT00502281
- Testing
- highly purified urinary FSH, timed intercourses, intrauterine insemination
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University Magna Graecia
Polycystic Ovary Syndrome
Research of Intensive Lifestyle Intervention for PCOS Patients With IGT
Compare the efficacy between intensive lifestyle intervention and drugs (GLP-1 Receptor Agonists, metformin and acarbose) for PCOS patients with early onset diabetes in their metabolic and reproductive abnormalities treatment…
- Trial name
- NCT02446834
- Testing
- intensive lifestyle intervention, GLP-1 Receptor Agonists, Metformin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Polycystic Ovary Syndrome, c Type Natriuretic Peptide
Comparison of Serum C Type Natriuretic Peptide Levels Between Polycystic Ovary Syndrome Patients and Healthy Women
Recent studies have shown that C natriuretic peptide is produced from granulosa cells, increasing cumulative guanosine monophosphate (cGMP) production by affecting cumulus cells through natriuretic peptide receptors.
- Conditions
- Polycystic Ovary Syndrome, c Type Natriuretic Peptide, Menstrual Irregularity, Hyperandrogenism
- Trial name
- CNP (NCT04006171)
- Testing
- C type natriuretic peptide
- Where
- Cyprus
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Polycystic Ovarian Syndrome
The Effect of Metformin on Different Hormones in PCOS Patients
Forty eight PCOS patients were included . The diagnosis of PCOS was made based on the three criteria set by the Rotterdam Consensus meeting definition of PCOS (ESHRE, ASRM, 2004). The criteria were as follows: 1.
- Trial name
- NCT02568488
- Testing
- Metformin
- Volunteers
- 48 people
- Sponsor
- Ahmed Maged
Polycystic Ovary Syndrome
Light Fasting Diet and Magnesium in Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age, which is associated with hormonal imbalances, dyslipidemia, chronic inflammation, and increased oxidative stress, and…
- Trial name
- NCT07322120
- Testing
- Light fasting, Magnesium supplementation
- Volunteers
- 46 people
- Sponsor
- Behnood Abbasi
Polycystic Ovarian Syndrome (PCOS), Reproductive Health
Management of Polycystic Ovarian Syndrome-associated Reproductive Dysfunction Through Kefir Supplementation
Polycystic ovary syndrome (PCOS) affect around 6-12% of women of age 18-25 years. Kefir contains bioactive compounds such as lactic acid bacteria, yeast, peptides, polysaccharides and organic acids and acts as a good probiotic…
- Trial name
- NCT07711782
- Testing
- (C0) Control group, (G1) Experimental group
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Lahore
Polycystic Ovary Syndrome, Infertility, Female
The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System
A Prospective, Multicenter, Randomized, Pivotal Study of the May Health System in Transvaginal Ablation of Ovarian Tissue under Ultrasound Guidance in Women with Infertility due to Polycystic Ovary Syndrome
- Trial name
- NCT06206746
- Testing
- May Health System
- Where
- 19 sites in United States
- Volunteers
- 93 people
- Sponsor
- May Health
Polycystic Ovary Syndrome
Therapeutic Monitoring of Metformin in Women With Polycystic Ovary Syndrome
Metformin is one of the most commonly prescribed drugs worldwide for the treatment of Type 2 Diabetes. It has been currently used for the treatment of: polycystic ovary syndrome, gestational diabetes, metabolic syndrome and…
- Trial name
- NCT01366391
- Testing
- Metformin
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Biocinese
Polycystic Ovary Syndrome
Use of Myo-inositol as Adjuvant Therapy in Patients With Polycystic Ovary Syndrome (PCOS) in Vitro Fertilization (IVF)
The original mechanism of action of myo-inositol and preliminary results available in the literature on its use in IVF suggest its value as adjuvant gonadotropin therapy to reduce the risk of OHSS in PCOS patients.
- Trial name
- FIV-INOPK (NCT02221154)
- Testing
- Inofolic®, Gonadotropins; Folic Acid
- Where
- 4 sites in France
- Volunteers
- 49 people
- Sponsor
- Centre Hospitalier Departemental Vendee
PCOS (Polycystic Ovary Syndrome)
The Aim of This Study is to Gain Insight Into the Occurrence of Irritable Bowel Symptoms During Ovarian Stimulation in Individuals With PCOS and in Women Who Wish to Freeze Their Eggs. This Study Uses Questionnaires.
This exploratory study investigates the impact of fertility treatments on symptoms of irritable bowel syndrome (IBS) in women. Specifically, the study focuses on two groups: Women with polycystic ovary syndrome (PCOS) who are…
- Trial name
- FIBS (NCT07533968)
- Testing
- questionnaires
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Vitamin D Receptor Defect
Endometrial Vitamin D Receptor in PCOS
Vitamin D receptor (VDR) is widely expressed not only in tissues responsible for calcium hemostasis, but also in reproductive organs, including the endometrium.
- Trial name
- NCT05885633
- Testing
- endometrial sampling with pipelle
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Uşak University
Polycystic Ovary Syndrome
A Reduced Carbohydrate Diet Intervention for Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) affects 5-10% of women of reproductive age, and is associated with infertility, risk for obesity and type 2 diabetes, and impaired quality of life.
- Trial name
- NCT01028989
- Testing
- Reduced Glycemic Load Diet, Standard Diet
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Polycystic Ovary Syndrome, Insulin Resistance
The Role of Insulin Resistance in PCOS
Polycystic ovary syndrome (PCOS) phenotype can be structured into three components: anovulation, hyperandrogenism and the metabolic syndrome (of which hyperinsulinemia, secondary to insulin resistance, is the central…
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Obesity
- Trial name
- NCT00173043
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hyperandrogenism, Polycystic Ovary Syndrome
Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?
The purpose of this study is to determine if, in mid- to late pubertal girls with hyperandrogenism (HA), androgen-receptor blockade (spironolactone) alone normalizes sleep-wake luteinizing hormone (LH) pulse frequency (primary…
- Conditions
- Hyperandrogenism, Polycystic Ovary Syndrome, Puberty
- Trial name
- CBS010 (NCT04723862)
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Myoma;Uterus, Vitamin D Deficiency
Vitamin D Levels And Myoma Uteri
Women with at least one uterine leiomyoma and polycystic ovary syndrome over 10 mm and women with normal ultrasonographic findings were included in the study.
- Conditions
- Myoma;Uterus, Vitamin D Deficiency, Polycystic Ovary
- Trial name
- NCT03871868
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Polycystic Ovary Syndrome
Effects of Gum Arabic Ingestion on Hormonal and Metabolic Changes in Patients With Polycystic Ovary Syndrome
To assess the effects on hormonal and metabolic changes in the PCOs patients after ingestion of Arabic gum
- Trial name
- GA&PCO (NCT04215380)
- Testing
- Acacia Senegal extract, Pectin
- Where
- Sudan
- Volunteers
- 60 people
- Sponsor
- Lamis Kaddam
Polycystic Ovary Syndrome
IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer
A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols include the use of the Steiner-Tan needle to optimize oocyte…
- Trial name
- IVMprt (NCT04149496)
- Testing
- in vitro maturation of oocytes
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Bruce Rose, MD
Polycystic Ovary Syndrome
High Versus Normal Protein Diet in Polycystic Ovary Syndrome (PCOS)
The objective of this study is to assess the effects of a high protein (HP) and a normal protein diet (NP) on patients with polycystic ovary syndrome (PCOS) and body mass index (BMI)-matched controls in a sample of southern…
- Trial name
- NCT01184963
- Testing
- High protein diet, Normal protein diet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Polycystic Ovary Syndrome
A Study to Explore Correlation Between Symptoms and Signs of Polycystic Ovarian Syndrome (PCOS) and Risk of Over-response to Ovarian Stimulation
This is a Phase IV, prospective, observational, single arm, multicenter trial to identify the population at high risk of overstimulation associated with signs and symptoms of PCOS and examines the utility of 12.5 international…
- Trial name
- ARTIST (NCT02607293)
- Testing
- Gonal-f®, Long GnRH agonist, GnRH antagonist
- Where
- Germany
- Volunteers
- 1,064 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
PCOS
IVM Versus Standard IVF in Infertile Patients Diagnosed With PCOS
A single center, prospective, open-label, non-inferiority randomized controlled clinical trials (1:1 treatment ratio) regarding pregnancy outcomes between IVM and standard IVF among infertility couples with PCOS in China.
- Trial name
- NCT03463772
- Testing
- standard IVF, In vitro maturation
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Jie Qiao
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.