Clinical trials: Polycystic Ovary Syndrome (PCOS)
Polycystic Ovary Syndrome, Insulin Resistance
PCOS & Insulin Resistance Exercise Study
This study evaluates the feasibility and metabolic effects of implementing a structured exercise program in women with polycystic ovary syndrome and insulin resistance.
- Trial name
- NCT02303470
- Testing
- Vigorous Exercise, Moderate Exercise
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Polycystic Ovary Syndrome
Treatment Benefits of Berberine Supplementation for Women With PCOS
Berberine is a plant alkaloid, reportedly possesses a wide range of pharmacological activities, including anti-obesity and anti-dyslipidemia.
- Trial name
- NCT05480670
- Testing
- Berberine
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Ayub Teaching Hospital
Polycystic Ovary Syndrome
Ocular Findings of Polycystic Ovary Syndrome
Purpose: This study aimed to compare the ocular surface disease test results, anterior segment parameters, and ocular response analyzer (ORA) findings of polycystic ovary syndrome (PCOS) patients with those of healthy…
- Trial name
- NCT03896841
- Testing
- Observation
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Polycystic Ovary Syndrome
Effects of GLP-1 Analogue Combined With Metformin and Metformin on Gonadal and Metabolic Profiles in Chinese Overweight/Obese PCOS Patients With Hyperandrogenemia.
To study the effects of GLP-1 analogues combined with metformin and metformin on gonadal and metabolic profiles in PCOS patients with BMI ≥ 24 in China. 60 cases of overweight PCOS patients were collected from Shengjing hospital.
- Trial name
- NCT04969627
- Testing
- Metformin, Exenatide
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Bing He
Polycystic Ovary Syndrome
Does Vaginal Delivery of Combined Hormonal Contraception Affect the Risk of Metabolic Syndrome in Overweight/Obese Women With PCOS
A prospective study to determine the metabolic effects of the contraceptive vaginal ring among overweight and obese women with polycystic ovary syndrome (PCOS).
- Trial name
- RING-PCOS (NCT04257500)
- Testing
- Etonogestrel/ethinyl estradiol vaginal ring
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Andrea Roe, MD, MPH
Polycystic Ovary Syndrome
Electroacupuncture on Menstrual Frequency in Women With Polycystic Ovary Syndrome: Study Protocol
Polycystic ovary syndrome (PCOS) is a dysfunction of endocrine system of women of reproductive age. Approximately 5%-10% women in China have this syndrome.
- Trial name
- NCT02653911
- Testing
- Acupuncture
- Volunteers
- 172 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Polycystic Ovarian Syndrome
Comparative Effects of Neurodynamic Stretch and Myofascial Pain Release in Polycystic Ovarian Syndrome.
The study will be a non-blinded randomized controlled trial, consisting of two groups. Non-probability Convenience sampling will be used to recruit participants who will meet the inclusion criteria.
- Trial name
- NCT07645014
- Testing
- Neurodynamic stretches, myofascial pain release technique Interventions:
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Polycystic Ovary Syndrome
Effect of Sitagliptin on Polycystic Ovarian Syndrome Patients
The Study aims to determine the proposed positive influence of Sitagliptin in manipulating hormonal , metabolic and inflammatory parameters in the treatment of Polycystic ovary syndrome and subsequent infertility
- Trial name
- NCT05972928
- Testing
- Sitagliptin 100mg
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
Polycystic Ovarian Syndrome (PCOS), Quality of Life
High Intensity Interval Training Versus Mat Pilates in Women With PCOS
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age and is associated with obesity, insulin resistance, poor physical fitness, and reduced quality of life.
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Quality of Life, Physical Fitness
- Trial name
- NCT07875400
- Testing
- High-Intensity Interval Training (HIIT), Mat Pilates group, General mobility exercises
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease
Liver Stiffness And Steatosis Assessment In Women With Polycystic Ovary Syndrome Using Fibroscan
Polycystic Ovary Syndrome (PCOS) is a complex endocrine and metabolic disorder prevalent among women of reproductive age. It is closely associated with insulin resistance, obesity, and metabolic dysfunction, often leading to…
- Trial name
- NCT07027332
- Testing
- FibroScan® (Echosens, Paris, France)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Polycystic Ovary Syndrome
The PCOS Challenge Study
The primary purpose of The PCOS Challenge Study will be to conduct high-quality research where patients are included in the design, and answering the questions that patients identify as important to their lived experience with…
- Trial name
- PCOSCHALLENGE (NCT05797909)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- PCOS Challenge: The National Polycystic Ovary Syndrome Association
Infertility and at High Risk of OHSS
Dual Trigger to Reduce Ovarian Hyperstimulation Syndrome
Gonadotropin releasing hormone (GnRH) agonist is sufficient for triggering final oocyte maturation in GnRH antagonist protocol and can significantly reduce incidence of ovarian hyperstimulation syndrome (OHSS) in high-risk…
- Trial name
- NCT02022228
- Testing
- triptorelin, hCG
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chenshiling
Infertility, Polycystic Ovary Syndrome
GnRH Antagonist Versus GnRH Agonist in Polycystic Ovary Syndrome During in Vitro Fertilization - Embryo Transfer
GnRH (Gonadotropin-releasing hormone) antagonists in IVF (in vitro fertilization) has been accomplished by several randomized controlled trials compared with conventional GnRH agonist long protocol in polycystic ovary syndrome…
- Trial name
- NCT01402336
- Testing
- GnRH antagonist (Cetrorelix), Conventional GnRH agonist (Triptorelin)
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Seoul National University Hospital
Polycystic Ovary Disease
"KETOGENIC MEDITERRANEAN VERSUS HYPOCALORIC BALANCED DIET ON POLYCYSTIC OVARIAN ADOLESCENTS"
study was designed to determine the effect of ketogenic Mediterranean diet versus hypocaloric balanced diet on adolescent female with polycystic ovary disease.
- Trial name
- keto- MEDITERR (NCT06610812)
- Testing
- KETOGENIC MEDITERRANEAN diet, hypo-caloric diet:, moderate aerobic exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MTI University
Ovulation Induction, Polycystic Ovary Syndrome
Myo-inositol Versus Clomiphene Citrate in PCOS
Specific aim: To compare inositol and the golden standard first line treatment of ovulation induction, namely clomiphene citrate.
- Conditions
- Ovulation Induction, Polycystic Ovary Syndrome, Clomiphene, Inositol
- Trial name
- NCT04306692
- Testing
- Myo-inositol, Clomiphene Citrate
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- University Hospital, Ghent
Polycystic Ovary Syndrome
Safety of Hormonal Contraceptives Therapies in Polycystic Ovary Syndrome (PCOS) Women
The purpose of this study to assess early markers of cardiovascular disease in women with polycystic ovary syndrome in use of oral contraceptive containing ethynilestradiol and chlormadinone acetate alone or associated with…
- Trial name
- NCT00842140
- Testing
- oral contraceptive, Oral contraceptive plus spironolactone, Oral contraceptive plus metformin
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- University of Sao Paulo
Polycystic Ovary Syndrome
Long Term Metformin in Women With Polycystic Ovary Syndrome
The investigators analyzed collection data of 10 years for the efficacy of metformin on body mass, menstrual frequencies, metabolic and hormonal outcomes in women with polycystic ovary syndrome (PCOS) and BMI ≥ 25kg/m2.
- Trial name
- NCT04043221
- Where
- Slovenia
- Volunteers
- 180 people
- Sponsor
- University Medical Centre Ljubljana
Infertility, Female, PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
The Effects of Acetyl-L-Carnitine and Myo/Chiro-Inositol in Patients With PCOS
The large number of women in their child bearing age is affected by Polycystic ovarian syndrome (PCOS) leading to infertility. However it is considered as a multisystem disorder with comorbidities rather than a gynecological and…
- Trial name
- PCOS (NCT05767515)
- Testing
- metformin
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Khyber Medical University Peshawar
Polycystic Ovary Syndrome, Ovulation Disorder
Clusterin Level and Polycystic Ovary Syndrome
Clusterin, a protein involved in metabolic syndrome, insulin resistance, and metabolic disorders associated with inflammation and oxidative stress such as atherosclerosis, Alzheimer's and some malignancies, has elevated levels in…
- Trial name
- NCT06601725
- Testing
- Clusterin level
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Polycystic Ovary Syndrome (PCOS)
Myo-Inositol Alone Versus Myo-Inositol Plus Alpha-Lactalbumin in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting reproductive-aged women and is associated with menstrual irregularities, infertility, hyperandrogenism, obesity, and insulin resistance.
- Trial name
- MIALA-PCOS (NCT07629895)
- Testing
- Myo-inositol, Alpha-Lactalbumin
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Quaid-e-Azam Medical College
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