Clinical trials: Polycystic Ovary Syndrome (PCOS)
Obesity, Hyperandrogenemia
Etiological Factors of Obesity-Associated Hyperandrogenemia in Peripubertal Girls
The purpose of this study is to learn if obese pre- and early pubertal girls with hyperandrogenemia (HA) are more insulin resistant (i.e., have lower insulin-stimulated glucose disposal) compared to obese peripubertal girls…
- Conditions
- Obesity, Hyperandrogenemia, Polycystic Ovary Syndrome
- Trial name
- CRM002 (NCT00928759)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome
Clinical and Basic Research on the Treatment of Polycystic Ovary Syndrome
Polycystic ovary syndrome is the most common endocrine and metabolic disorder in gynecology. Traditional Chinese medicine has a good clinical effect in the treatment of PCOS.
- Trial name
- NCT04120597
- Testing
- Zishen Qingre Lishi Huayu Granules
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Obesity, Hyperlipidemias
Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients
Developed nations worldwide are currently enduring a health crisis, as chronic diseases continue to decrease quality of life and promote additional disease states or even death for much of the population.
- Conditions
- Obesity, Hyperlipidemias, Polycystic Ovary Syndrome, Hypertension
- Trial name
- NCT06049420
- Testing
- Lifestyle counseling and coaching
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- West Virginia School of Osteopathic Medicine
Obesity & Overweight, Diabetes Mellitus, Type 2
Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks
This is a nationwide, multi-center, long-term follow-up study of overweight and obese adults in China. The study aims to recruit approximately 26,000 participants across 39 hospitals to better understand how body weight affects…
- Conditions
- Obesity & Overweight, Diabetes Mellitus, Type 2, Hypertension, Non-alcoholic Fatty Liver Disease (MASLD)
- Trial name
- NCT07884903
- Testing
- No intervention; observational assessment only
- Where
- China
- Volunteers
- 25,974 people
- Sponsor
- Shanxi Bethune Hospital
Polycystic Ovary Syndrome
Serum Metabolomics Study of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a complex, heterogeneous disorder, which produces in 5-20% reproductive age women. In this study, a nontargeted metabolomics approach based on ultra high-performance liquid chromatography…
- Trial name
- NCT03618342
- Where
- China
- Volunteers
- 1,272 people, healthy volunteers welcome
- Sponsor
- Heilongjiang University of Chinese Medicine
Polycystic Ovary
The Supporting Understanding of PCOS Education and Research (SUPER) Study
This research will test whether a Dietary Approaches to Stop Hypertension (DASH) or a very low-carbohydrate diet better improves outcomes like blood glucose control and body weight for adults with polycystic ovary syndrome.
- Trial name
- SUPER (NCT05452642)
- Testing
- DASH diet, Very low-carbohydrate diet
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- University of Michigan
Polycystic Ovary Syndrome
Effects of Alpha-acid Lipoic in PCOS Women
The aim of our study is to investigate the effects of six months treatment with alpha-lipoic acid on clinical, endocrine and metabolic features in women affected by PCOS.
- Trial name
- NCT02666170
- Testing
- Alpha-lipoic acid
- Volunteers
- 40 people
- Sponsor
- Catholic University of the Sacred Heart
PCOS
The Effect of Astaxanthin on Oxidative Stress Indices in Patients With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age It is hypothesized that ∼20 fold increase in reactive oxygen species (ROS) generation in Follicular fluid (FF) and granulosa…
- Trial name
- NCT03991286
- Testing
- Astaxanthin 8 mg
- Where
- Iran
- Volunteers
- 48 people
- Sponsor
- Tehran University of Medical Sciences
Polycystic Ovary Syndrome
Prevalence of Polycystic Ovary Syndrome In Trinidad
According to World Health Organization (WHO), in 2010, Polycystic Ovarian Syndrome (PCOS) affected approximately 116 million women worldwide (3.4% of the population).
- Trial name
- NCT05937360
- Testing
- cross-sectional community based study
- Where
- Trinidad and Tobago
- Volunteers
- 300 people
- Sponsor
- The University of The West Indies
Polycystic Ovary Syndrome
n-3 Polyunsaturated Fatty Acids (PUFA) Supplementation in Young Women With Polycystic Ovary Syndrome (PCOS)
This is a dietary intervention study designed to assess the impact of long chain (LC) n-3 polyunsaturated fatty acids (PUFA) in young women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT01189669
- Testing
- LC n-3 PUFA (fish oil) Supplement
- Where
- 2 sites in Ireland
- Volunteers
- 25 people
- Sponsor
- The Adelaide and Meath Hospital
Polycystic Ovarian Syndrome
Comparison of Clomid and Lezra With Lezra for Ovulation Induction in Clomid Resistant PCOS Case
Clomiphene citrate resistant i.e failure to ovulate after 6 cycles of ovulation induction effects 15-40% of patients with PCOS.Two treatment groups will be formed one recieving letrozole alone and another recieving CC and…
- Trial name
- NCT06813118
- Testing
- Clomiphene Citrate and letrozole
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- HITEC-Institute of Medical Sciences
Polycystic Ovary Syndrome
IVM With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Transfer
A protocol was developed to improve pregnancy results after IVM compared to results from studies in the literature. Differences from most published protocols include the use of the Steiner-Tan needle to optimize oocyte…
- Trial name
- IVMprt (NCT04149496)
- Testing
- in vitro maturation of oocytes
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Bruce Rose, MD
Polycystic Ovary Syndrome, Infertility
Treatment of Infertility in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting up to 10% of women. The primary symptoms of PCOS are menstrual irregularities, increased body and facial hair, acne, and infertility.
- Conditions
- Polycystic Ovary Syndrome, Infertility, Pregnancy
- Trial name
- NCT00068861
- Testing
- metformin XR, clomiphene citrate
- Where
- 11 sites in United States
- Volunteers
- 678 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
PCOS, NAFLD
Lifestyle Changes in PCOS with OSA and NAFLD
Complain of obstructive sleeping apnea and fatty liver is common in PCOS women so lifestyle changes are recommended
- Conditions
- PCOS, NAFLD, OSA
- Trial name
- NCT06591169
- Testing
- diet restriction and exercise, diet restriction
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Pregestational Obesity (BMI > 27kg/m2), History of Polycystic Ovary Syndrome
Medical Nutrition Therapy Plus Transgestational Metformin For Preventing Gestational Diabetes In High Risk Mexican Women
Gestational diabetes mellitus is one of the most frequent complications of pregnancy, that affect between 1 to 14% of population around the world.
- Trial name
- NCT01675310
- Testing
- medical nutrition therapy + metformin, Medical nutrition therapy
- Where
- Mexico
- Volunteers
- 90 people
- Sponsor
- Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Polycystic Ovary
Serum Ghrelin in Polycystic Ovary Syndrome
measuring serum gherlin in polycystic ovary syndrome patients and compare it to healthy levels
- Trial name
- NCT02087410
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- amr hesham el etreby
Polycystic Ovary Syndrome
Predictive Equations for Resting Energy Expenditure
Predictive equations are the main clinical tool for determining resting energy expenditure (REE). Thus, it is important to investigate the accuracy and agreement of these equations in different populations and context of…
- Trial name
- NCT02435888
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Minas Gerais
Menstrual Disorders, Polycystic Ovary Syndrome
Homoeopathy and Yoga in the Treatment of Menstrual Disorders in Females With Polycystic Ovarian Syndrome
This study is undertaken to compare effectiveness of homoeopathic treatment versus integrated approach of homoeopathy and yoga in the treatment of menstrual disorders in females with Polycystic ovarian syndrome.
- Trial name
- NCT03579303
- Testing
- Homoeopathic Remedies
- Where
- India
- Volunteers
- 84 people
- Sponsor
- Fr Muller Homoeopathic Medical College
Polycystic Ovary Syndrome, Healthy
Ovarian Response to Recombinant Follicle Stimulating Hormone in Women With PCOS
Women with PCOS suffer from anovulation and, as a result, infertility. Efforts to clinically induce ovulation in these women using follicle stimulating hormone (FSH) administered subcutaneously seemingly requires prolonged…
- Conditions
- Polycystic Ovary Syndrome, Healthy, Anovulation, Hyperandrogenism
- Trial name
- NCT03252223
- Testing
- Recombinant Follicle Stimulating Hormone
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Polycystic Ovary Syndrome
Effect of High Intensity Interval Training on Insulin Resistance in Polycystic Ovarian Syndrome
This study will be conducted to investigate the effect of high- intensity interval training on insulin resistance in polycystic ovarian syndrome.
- Trial name
- NCT07708766
- Testing
- Intermittent fasting diet group, High intensity interval training
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
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