Clinical trials: Polyethylene Glycol Solution
Healthy
Safety, Tolerance, and Pharmacokinetics of Single Oral Doses of BI 201335 NA and Bioavailability in Healthy Male Subjects
The objective of this study was to investigate the safety, tolerability, and pharmacokinetics of BI 201335 NA following administration of single rising doses from 4 mg to 1200 mg.
- Trial name
- NCT02182323
- Testing
- BI 201335 NA
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Safety, Tolerance, and Pharmacokinetics of Single Rising Oral Doses of BILB 1941 ZW Solution in Healthy Male Subjects, Followed With Bioavailability Comparison of BILB 1941 ZW Tablet and Solution Formulation Administered With or Without Food
The objective of the current study was to investigate the safety, tolerability, and pharmacokinetics of BILB 1941 ZW following the administration of single rising doses from 5 mg to 300 mg.
- Trial name
- NCT02256787
- Testing
- BILB 1941 ZW - single rising dose part, BILB 1941 ZW - solution, BILB 1941 ZW - tablet
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Safety, Tolerability, and Pharmacokinetics of Single Rising Oral Doses of BIRB 1017 BS as a Solution in PEG 400 / 26% Ethanol Administered to Healthy Male Subjects
Study to assess safety, tolerability and pharmacokinetics of BIRB 1017 BS in single rising oral doses of 5 to 800 mg in a polyethylene glycol 400 (PEG 400) / 26% ethanol solution in healthy male subjects
- Trial name
- NCT02184338
- Testing
- BIBR 1017 BS powder
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Bowel Preparation Before Colonoscopy
A Trial to Evaluate the Efficacy and Safety of PMF104 Compared to a Conventional PEG-electrolyte Solution in Children
A randomised, single-blind, active controlled, multi-centre trial to evaluate the efficacy, safety, tolerability, acceptability and palatability of PMF104 compared to a conventional PEG-electrolyte solution in paediatric subjects…
- Trial name
- NCT03106922
- Testing
- PMF104, Klean-prep
- Where
- 9 sites in Belgium, France and 1 more
- Volunteers
- 430 people
- Sponsor
- Alfasigma S.p.A.
Elective Colonoscopy
Efficacy and Safety of mAnnitol in Bowel Preparation During Elective Colonoscopy and Comparison With Moviprep®
The purpose of this dose finding/comparative efficacy study is to first single out the most appropriate dose of mannitol for bowel preparation (phase II) and, subsequently, demonstrate the non-inferiority of the efficacy of…
- Trial name
- SATISFACTION (NCT04759885)
- Testing
- Phase II: NTC015 low dose, Phase II: NTC015 medium dose, Phase II: NTC015 high dose
- Where
- 35 sites in France, Germany and 2 more
- Volunteers
- 886 people
- Sponsor
- NTC srl
Constipation
Safety and Tolerability of Oral Polyethylene Glycol (PEG 3350) Solution in Participants With Constipation (MK-8114-003)
The purpose of this study is to compare the safety and tolerability of oral ingestion of PEG 3350 solution concentrate to oral ingestion of a placebo solution concentrate, in participants with constipation.
- Trial name
- NCT01885104
- Testing
- Polyethylene Glycol (PEG 3350), Bisacodyl laxative tablets (rescue medication)
- Volunteers
- 65 people
- Sponsor
- Bayer
Colonoscopy
Comparison of 2L NRL994 With NaP Preparation in Colon Cleansing Prior to Colonoscopies for Colon Tumor Screening
To compare the efficacy, acceptability and safety of the new 2 liter gut cleansing solution (Moviprep) and NaP preparation in routine colon cleansing prior to tumor screening colonoscopies
- Trial name
- NCT00427089
- Testing
- Macrogol 3350 Na sulphate NaCl KCl Ascorbic Acid Na Ascorbate, Sodium Phosphate solution (NaP)
- Where
- 12 sites in Germany
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Norgine
Healthy
Safety, Tolerance, and Pharmacokinetics of BILN 2061 ZW in Healthy Male Subjects, Combined With Preliminary Evaluation of Food Effect
To assess the safety, tolerance and pharmacokinetics of 5 mg to 2400 mg BILN 2061 ZW 1. In rising single doses 2. With and without a 64 g fat breakfast at one selected dose
- Trial name
- NCT02268760
- Testing
- BILN 2061 ZW single rising doses, BILN 2061 ZW fixed dose, Standardized breakfast
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Colonoscopy
Investigation of PICOPREP and PEG-ELS for Bowel Preparation for Colonoscopy
Eligible subjects undergoing a colonoscopy will randomly receive either PICOPREP or polyethylene glycol 4000 electrolyte lavage solution before the procedure to evaluate its effectiveness, tolerability and safety.
- Trial name
- NCT01356407
- Testing
- PICOPREP, PEG-ELS
- Where
- 7 sites in China
- Volunteers
- 300 people
- Sponsor
- Ferring Pharmaceuticals
Constipation
Comparison of PEG Solutions With and Without Electrolytes in the Treatment of Constipation
The aim of the study is to show that new polyethylene glycol (PEG) solution without electrolytes is as effective in the treatment of constipation as PEG solution with electrolytes in the elderly institutionalized people.
- Trial name
- PEGorion (NCT00603681)
- Testing
- Polyethylene glycol 4000, Polyethylene glycol 4000 with electrolytes
- Where
- 10 sites in Finland
- Volunteers
- 67 people
- Sponsor
- Orion Corporation, Orion Pharma
Healthy
Single Rising Dose Study of BI 201335 ZW in Healthy Male Subjects
The objective of the current study is to investigate safety, tolerability, and pharmacokinetics of BI 201335 ZW following administration of single rising doses from 5 mg to 1500 mg.
- Trial name
- NCT02182271
- Testing
- BI 201335 ZW - single rising dose
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Safety, Pharmacokinetics, and Pharmacodynamics of BIRT 2584 XX in Healthy Male Volunteers
To assess safety, tolerability, pharmacokinetics, and pharmacodynamics of BIRT 2584 XX in single rising oral doses of 5 mg to 700 mg in a polyethylene glycol 400 (PEG 400) solution in healthy subjects
- Trial name
- NCT02259894
- Testing
- BIRT 2584 XX
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Safety, Pharmacokinetics and Pharmacodynamics of BIRT 1696 BS in Healthy Human Subjects
The objectives are: 1. To assess safety, pharmacokinetics, and pharmacodynamics of BIRT 1696 BS in rising single doses. 2. To assess safety, pharmacokinetics, and pharmacodynamics of single dose of 100 mg BIRT 1696 BS after…
- Trial name
- NCT02254096
- Testing
- BIRT 1696 BS, Grapefruit juice (GFJ), High fat meal (HFM)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim