Clinical trials: Polymers
Dentin Sensitivity
Exploratory Clinical Study to Investigate the Ability of an Experimental Combination Dentifrice to Protect Sensitive Teeth
This proof of principle (PoP) study will evaluate the ability of an experimental combination toothpaste formulation to protect sensitive teeth from dentine hypersensitivity.
- Trial name
- NCT05243745
- Testing
- 3% PVM/MA + 5% KNO3 Combination, 3% PVM/MA only, 5% KNO3 Only
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- HALEON
Infection, Post-operative Care
The Use of a Novel Microbicidal Liquid Polymer for the Reduction of Pin Track Infection
The purpose of the study is to investigate additional clinical uses for the polymer, which is a FDA approved, 510k, medical device, but has not been approved for use on patients with pin track sites as a way to lower the…
- Trial name
- NCT03756506
- Testing
- Novel Microbicidal Liquid Polymer
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Prevent-Plus LLC
Healthy
Bioavailability Study of 300 mg Trazodone Hydrochloride (New Polymer) vs. 300 mg Trazodone Hydrochloride (Contramid® Prolonged-release Tablets) Under Fasting Conditions
This study was designed to investigate the bioequivalence of the test and reference products when administered as single oral doses in two consecutive study periods, under fasting conditions.
- Trial name
- NCT05136521
- Testing
- Trazodone HCl - new polymer, Trazodone HCl - Contramid®
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Bioavailability Heathy Volunteers, Bioavailability Study
Bioavailability of Trazodone Hydrochloride (New Polymer) vs. Trazodone Hydrochloride Contramid® at Steady-state.
Two way, two parallel groups, crossover study to compare the bioavailability of 150 mg and 300 mg trazodone hydrochloride (new polymer) (Angelini Pharma S.p.A.) vs.
- Conditions
- Bioavailability Heathy Volunteers, Bioavailability Study, Bioequivalance
- Trial name
- NCT06773767
- Testing
- 150 mg trazodone hydrochloride, 300 mg trazodone hydrochloride
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
HIV Infections, Gonorrhea
Trial to Evaluate PRO 2000/5 Gels for the Prevention of Vaginally Acquired HIV Infection
The objective of the study is to determine the efficacy and safety of 0.5% and 2% PRO 2000/5 gels compared to placebo in preventing vaginally acquired HIV infection.
- Conditions
- HIV Infections, Gonorrhea, Chlamydial Infections, Genital Herpes
- Trial name
- NCT00262106
- Testing
- PRO 2000/5
- Where
- 6 sites in South Africa, Tanzania and 2 more
- Volunteers
- 9,404 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Healthy
A Novel Mouthwash Formulation CTP/BNZ With Mucus Adhesive Polymer
The purpose of the study is to evaluate the local tolerability and the systemic availability of benzydamine, if any, after single and multiple dose treatment with the test formulation containing cetylpyridinium chloride 0.05% +…
- Trial name
- NCT03706781
- Testing
- Cetylpyridinium Chloride 0.05% + Benzydamine HCl 0.15% + mucus adhesive polymer, Cetylpyridinium Chloride 0.05% + Benzydamine HCl 0.15%
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A