Clinical trials: Polymers
Metastatic Breast Cancer, Stage IV Breast Cancer
BP-C1 in Short-term Treatment of Thai Patients With Metastatic Breast Cancer
The purpose of this study is to determine whether BP-C1 is effective in the short-term treatment of metastatic breast cancer patients who have previously undergone at least three lines of chemotherapy.
- Trial name
- NCT03603197
- Testing
- BP-C1
- Where
- 4 sites in Thailand
- Volunteers
- 38 people
- Sponsor
- Meabco A/S
Angina, Unstable, Non-ST-Segment Elevation Myocardial Infarction
OCT Based Edge and In-stent Vascular Response After Cordimax Stent in patIents With NSTE-ACS
This study evaluates the completeness of strut coverage and vessel wall response, at different time points (3-6-12 Months), following CordimaxTM stent implantation in patients with non-ST elevation acute coronary syndrome
- Trial name
- NCT02868203
- Testing
- OCT, eLuting stent
- Volunteers
- 80 people
- Sponsor
- Xijing Hospital
Ballet Dancers, Caries, Cervical
PICN Versus Bioactive Composite for Cervical Restorations in Ballet Dancers
Background and Objectives: Professional ballet dancers endure high occlusal loads, increasing cervical defect prevalence. Conventional composites fail frequently under such conditions.
- Trial name
- NCT07598305
- Testing
- Polymer-infiltrated ceramic network (PICN) - carious, Polymer-infiltrated ceramic network (PICN) - abfraction, Self-curing bioactive bulk-fill composite - carious
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Gastric Distress, Running Performance
A Low-osmolaric Glucose Polymer Drink for Gastric Distress and Running Performance
The objective of this study is to investigate whether two newly developed sports drink will affect gastric distress (GD) and running performance (RP) compared to an iso-caloric control drink both in a short and longer distance…
- Trial name
- NCT02401152
- Testing
- Sports drink 1, Sports drink 2
- Where
- Netherlands
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- InnoSportNL
HIV Infections, Gonorrhea
Trial to Evaluate PRO 2000/5 Gels for the Prevention of Vaginally Acquired HIV Infection
The objective of the study is to determine the efficacy and safety of 0.5% and 2% PRO 2000/5 gels compared to placebo in preventing vaginally acquired HIV infection.
- Conditions
- HIV Infections, Gonorrhea, Chlamydial Infections, Genital Herpes
- Trial name
- NCT00262106
- Testing
- PRO 2000/5
- Where
- 6 sites in South Africa, Tanzania and 2 more
- Volunteers
- 9,404 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Ischemic Heart Disease
GENOSS Coronary Stent Clinical Trial
This study aims to evaluate the efficacy and safety of abluminal biodegradable polymer ultrathin sirolimus-eluting stent (Genoss stent) as compared with a durable-polymer everolimus-eluting stent (Xience stent) in patients with…
- Trial name
- NCT05444452
- Testing
- Implanatation of Genoss DES sirolimus-eluting coronary system, Implanatation of Xience DES everolimus-eluting coronary system
- Where
- South Korea
- Volunteers
- 850 people
- Sponsor
- Samsung Medical Center
Ischaemic Heart Disease
BIOFREEDOM Stent Versus ORSIRO Stent: SORT OUT IX
The aim of the Danish Organization for Randomized Trials with Clinical Outcome (SORT OUT) is to compare the safety and efficacy of the polymer-free Biolimus-eluting BIOFREEDOM stent with a biodegradable-polymer Sirolimus-eluting…
- Trial name
- SORT OUT IX (NCT02623140)
- Testing
- Biofreedom, Orsiro
- Where
- Denmark
- Volunteers
- 3,150 people
- Sponsor
- Odense University Hospital
Surgically-Created Resection Cavity
Cranial Reconstruction Using Mesenchymal Stromal Cells and Resorbable Biomaterials
Formal study hypothesis: Cranial reconstruction using mesenchymal stromal cells and resorbable biomaterials, will result in the patient producing their own bone to fill the void which will reduce the risk of infection and…
- Trial name
- NCT01742260
- Testing
- Repair of cranial defects by tissue engineering
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- R.P.Herrmann
Unrecognized Condition
Effect of TCFA on Neointimal Coverage After PCI at 9 Months Follow-up
Although drug-eluting stents have reduced rates of restenosis and late lumen loss compared with bare metal stents, late stent thrombosis (LST), a life-threatening complication of this technology, has emerged as a major concern.
- Trial name
- NCT02384837
- Testing
- EXCEL biodegradable polymer-coated sirolimus-eluting stent
- Where
- China
- Volunteers
- 33 people
- Sponsor
- General Hospital of Chinese Armed Police Forces
Aneurysmal Bone Cyst
Use of Stem Cells Cultured on a Scaffold for the Treatment of Aneurysmal Bone Cysts (ABC)
Patients qualified for this study are those diagnosed with ABCs and failed to be treated with other forms of classical therapies.
- Trial name
- NCT03066245
- Testing
- MSC-PLGA
- Where
- Jordan
- Volunteers
- 4 people
- Sponsor
- Sophia Al-Adwan
Coronary Artery Disease
Vessel Injury in Relation With Strut Thickness Assessed by OCT
The objective of the present study is to determine the relation between vascular injury induced by the stent and strut thickness.
- Trial name
- VISTA (NCT03026465)
- Testing
- Polymer-free stent, Biodegradable-polymer stent
- Where
- 3 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
Coronary Artery Disease
Procedural Advantages of a Novel Drug-Eluting Coronary Stent
This study sought to compare procedural performance of a new coronary stent generation, that is already available in Germany, with hitherto established current drug-eluting stents.
- Trial name
- NCT02881216
- Testing
- Synergy Stent, Currently common drug-eluting stent (DES)
- Volunteers
- 814 people
- Sponsor
- University Hospital Heidelberg
Coronary Artery Disease, Angina Pectoris
Bioresorbable Polymer ORSIRO Versus Durable Polymer RESOLUTE ONYX Stents
The introduction of drug-eluting stents (DES) in the treatment of coronary artery disease has led to a significant reduction in morbidity.
- Conditions
- Coronary Artery Disease, Angina Pectoris, Unstable Angina Pectoris, Acute Coronary Syndrome
- Trial name
- BIONYX (NCT02508714)
- Testing
- Orsiro, Resolute Onyx
- Where
- 7 sites in Belgium, Israel and 1 more
- Volunteers
- 2,470 people
- Sponsor
- Thorax Centrum Twente
Coronary Artery Disease
HELIOS China Registry: Evaluation of the HELIOS Stent in a 'Real-World' Patient Population
The study aims to evaluate the safety and efficacy of biodegradable polymer sirolimus-eluting coronary stent system (HELIOS) in patients with coronary artery disease .
- Trial name
- NCT03916432
- Testing
- HELIOS biodegradable polymer sirolimus-eluting stents
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Xijing Hospital
Low Back Pain
Study to Evaluate Ferris PainWrap in the Treatment of Chronic Low Back Pain
The purpose of this study is to see if the Ferris PainWrap is effective in the treatment of chronic low back pain.
- Trial name
- NCT00364065
- Testing
- Ferris PainWrap
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Pain and Rehabilitation Medicine
Appendectomy
Closure of the Appendiceal Stump
Laparoscopic appendectomy is a well-defined surgical technique. However, concerns remain about whether closure of the appendiceal stump should be done with clips, endoloops, staples, or other techniques.
- Trial name
- NCT06443749
- Testing
- appendectomy
- Volunteers
- 48 people
- Sponsor
- Sezgin Topuz
Common Cold
A Study of an Experimental Nasal Spray in Subjects With Early Signs of the Common Cold
This study will test 200 people to see if an experimental nasal spray has an effect on symptoms of the common cold if used when the symptoms start.
- Trial name
- NCT01488604
- Testing
- Polymeric Nasal Spray
- Where
- 3 sites in United Kingdom
- Volunteers
- 163 people
- Sponsor
- McNeil AB
Sirolimus-eluting Stainless Steel Coronary Stent Prolim®
First-in-man Sirolimus-eluting Prolim® Stent Registry
The aim of this study was to assess the safety and the efficacy of the novel sirolimus-eluting Prolim® stent with a biodegradable polymer in the all-comers population.
- Trial name
- NCT02545985
- Testing
- Prolim stent deployment
- Volunteers
- 204 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Severe Malnutrition, Enteritis
Hypoallergenic and Anti-inflammatory Feeds in Malawian Children With Severe Acute Malnutrition (SAM)
Children with complicated severe acute malnutrition (SAM), such as inability to take adequate feeds, infection and diarrhoea, require in-patient management.
- Trial name
- SAM (NCT02639416)
- Testing
- Polymeric formula, Elemental formula, Standard management
- Where
- Malawi
- Volunteers
- 95 people
- Sponsor
- Liverpool School of Tropical Medicine
Percutaneous Coronary Angioplasty
Angiographic and IVUS Follow-up After Simultaneously Implanted Different Drug-eluting Stents in Same Individuals (AIFSIDDES)
The safety and efficacy of drug-eluting stents (DES) with a biocompatible polymer have been demonstrated in randomized clinical trials as well as in real world practice.
- Trial name
- NCT01382043
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Liuhuaqiao Hospital