Clinical trials: Polyp, Colonic
Colon Polyp, Colon Adenoma
Impact of Screen Size on Colorectal Adenoma Detection
The purpose of this study is to assess whether the use of large screen during colonoscopy will increase adenoma detection rate.
- Conditions
- Colon Polyp, Colon Adenoma, Colorectal Neoplasms
- Trial name
- NCT04749303
- Testing
- Large Screen
- Where
- Hong Kong
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Polyps, Adenoma Colon
Early DiAgnosis Real-Time Healthcare System for CANcer Trial
The purpose of the study is to assess whether the AI characterisation system of the CADDIE device improves the endoscopists accuracy in the optical diagnosis of diminutive colorectal polyps in the bowel during colonoscopy.
- Conditions
- Polyps, Adenoma Colon, Colorectal Polyp, Colon Polyp
- Trial name
- EARTHSCAN (NCT05064124)
- Testing
- CADDIE - Computer Aided Detection and Diagnosis for Intelligent Endoscopy
- Where
- United Kingdom
- Volunteers
- 420 people
- Sponsor
- University College, London
Familial Adenomatous Polyposis, Colorectal Cancer
Multimedia Intervention in Patients With Familial Adenomatous Polyposis (FAP)
The goal of this research study is to test the first version of a website that will offer information and support for adolescents and young adults with FAP.
- Trial name
- NCT00525655
- Testing
- Web-Based Multimedia Intervention, Questionnaire
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- M.D. Anderson Cancer Center
Colonic Polyps
Efficacy and Safety of Precut-EMR for Resecting of Colonic Polyp
This study was attempted to determine the efficacy and complication of precut EMR comparing with convetional EMR for resecting of 10 ~ 20 mm colon polyp through prospective, randomized controlled trial.
- Trial name
- NCT04253990
- Testing
- Precut EMR, Conventional MER
- Where
- South Korea
- Sponsor
- Asan Medical Center
Screening Colonoscopy, Colonoscopic Control After Polypectomy
Study on the Use of Artificial Intelligence (Fujifilm) for Polyp Detection in Colonoscopy
Colonoscopy is currently the best method of detection of intestinal tumors and polyps, particularly because polyps can also be biopsied and removed.
- Conditions
- Screening Colonoscopy, Colonoscopic Control After Polypectomy, Suspected Colon Polyps
- Trial name
- Fuji AI (NCT04894708)
- Testing
- colonoscopy
- Where
- 10 sites in Germany
- Volunteers
- 1,572 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Colorectal Cancer, Colorectal Neoplasms
Investigating the Use of Fluorescent Lectins to Identify Dysplasia and Cancer During Endoscopy and Surgery
This is a feasibility study investigating the use of a fluorescently conjugated lectin to identify colorectal dysplasia and cancer during colonoscopy and surgery.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp
- Trial name
- NCT03070613
- Testing
- Fluorescent Lectin Application
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Oxford
Adenomatous Polyps
Detection of Ileoanal Pouch/Reservoir Adenomas
The detection of adenomas is the basis for the follow-up of patients with familial adenomatous polyposis, after colectomy, with a remnant rectum or an ileal pouch. The optimal method for the adenomas detection is not defined yet.
- Trial name
- DARIAC (NCT05954949)
- Testing
- Adenomas detection rate with the different observation methods
- Volunteers
- 40 people
- Sponsor
- Jean Christophe Saurin
ColoRectal Cancer, Colonic Polyps
Feasibility of Check-Cap's P1 Capsule System Screening
Prospective, Single arm, Multi-Center 1. To establish the safety and preliminary efficacy of the Check-Cap System in patients with negative FOBT (Fecal Occult Blood Test) 2.
- Trial name
- NCT01458925
- Testing
- The P1 Check-Cap capsule
- Where
- Israel
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Polyp of Colon
Combining Artificial Intelligence With Balloon Mucosal Exposure Device for Polyp Detection in Screening Individuals
The present trial is aimed at evaluating whether in individuals scheduled for colonoscopy in the framework of a structured FIT (Fecal Immunochemical stool test)-based colorectal cancer screening program, the combination of an AI…
- Trial name
- COMBAT (NCT05829447)
- Testing
- G-EYE 760 R endoscope
- Where
- Italy
- Volunteers
- 686 people
- Sponsor
- Valduce Hospital
Colonic Neoplasm
Narrow Band Imaging for Diagnosis of Proximal Serrated Polyps
Although colonoscopy is considered the gold standard for diagnosis of colonic polyps, the missed rate for colonic adenoma ranged from 15-32%.
- Trial name
- NCT01725321
- Testing
- Narrow band imaging
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colorectal Cancer
Is Barium Enema an Adequate Diagnostic Test for Patients With Positive FOBT?
The research protocol aim is to compare diagnostic tools for the proper evaluation of patient with fecal occult blood test positive (FOBT +), a routine screening test for colorecatl carcinoma.
- Trial name
- DCBE (NCT00619814)
- Testing
- Double-contrast Barium enema, colonoscopy
- Volunteers
- 50 people
- Sponsor
- VA Caribbean Healthcare System
Colonoscopy, Colon Polyps
A Study of AQUAVAN® Injection Versus Midazolam HCl for Sedation in Elderly Patients Undergoing Elective Colonoscopy
This study was designed to demonstrate that AQUAVAN® is effective in providing adequate sedation in elderly patients undergoing colonoscopy as well as to assess the safety profile of AQUAVAN versus that of midazolam.
- Trial name
- NCT00209599
- Testing
- fospropofol disodium
- Volunteers
- 100 people
- Sponsor
- Eisai Inc.
Colonic Polyps, Colonic Cancers
Trial for Single Port Versus Conventional Laparoscopic Colectomy
This study aims to compare the outcomes of patients who undergo single-port laparoscopic colectomy and conventional laparoscopic colectomy for colonic neoplasia (large polyp not amenable to endoscopic removal/ cancer) through a…
- Trial name
- NCT01101672
- Testing
- Single port laparoscopic colectomy, Conventional laparoscopic colectomy
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Colonic Polyps
Acetic Acid for Optical Characterization of Colonic Polyps
Adenomas and hyperplastic polyps are polypoid lesions that can occur in any part of the colon. Currently all polyps should be resected endoscopically, however adenomas have the potential to develop into colorectal cancer whereas…
- Trial name
- ATOMIC I (NCT02760381)
- Testing
- NBI + Acetic Acid (AA)
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Technical University of Munich
Colon Polyps, Colorectal Cancer
Study of KCC Peptide Application in the Colon
We are studying new ways to look for abnormal areas/tissues of the colon during a colonoscopy. The current scopes used for colonoscopies are very good.
- Conditions
- Colon Polyps, Colorectal Cancer, Inflammatory Bowel Disease (IBD)
- Trial name
- KCC 1B (NCT02156557)
- Testing
- Colon KCC Heptapeptide
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Danielle Kim Turgeon
Colonic Polyps
The Value of Polyp Surface Pattern Recognition in the Identification of Neoplasia: a Prospective Study
It is current practice to remove any polyps found during colonoscopy. This is because adenomatous polyps have the potential to turn into cancer.
- Trial name
- NCT01182623
- Testing
- Observation of surface patterns of polyps
- Where
- United Kingdom
- Volunteers
- 260 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Colonic Polyp
Prospective, Randomized, Parallel Clinical Controlled Study of Early Diet Opening on Postoperative Gastrointestinal Hemorrhage in Patients With Colonic Polyps
Currently, hemorrhage remains the most common postoperative complication in patients with colon polyps, with an incidence of approximately 1.5%.
- Trial name
- NCT05466903
- Testing
- Early diet opening
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Right Colon Adenoma Miss Rate, Right Colon Hyperplastic Polyp Miss Rate
Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy
This will be a prospective randomized controlled trial comparing CO2 insufflation and WE in terms of right colon combined adenoma miss rate (AMR) and hyperplastic polyp miss rate (HPMR) by tandem inspection.
- Trial name
- NCT03845933
- Testing
- Colon polypectomy
- Where
- Taiwan
- Volunteers
- 262 people
- Sponsor
- Evergreen General Hospital, Taiwan
Familial Adenomatous Polyposis, Duodenal Neoplasms
Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis
Duodenal carcinomas are the leading cause of mortality in patients with Familial Adenomatous Polyposis (FAP) who underwent prophylactic colorectal surgery.
- Conditions
- Familial Adenomatous Polyposis, Duodenal Neoplasms, Duodenal Polyps
- Trial name
- PreDuoFAP (NCT00808743)
- Testing
- Celecoxib, Ursodeoxycholic acid
- Where
- 5 sites in Netherlands
- Volunteers
- 37 people
- Sponsor
- Radboud University Medical Center
Colonic Adenoma, Colonoscopy
Blue Laser Imaging and White Light Imaging Colonic Polyps
The adenoma detection rate by colonoscopy for asymptomatic individuals aged 50 years and older is estimated to be at least 25%. It is known that during colonoscopy, lesions may be missed.
- Trial name
- NCT03421600
- Testing
- blue laser imaging, White light imaging
- Where
- Singapore
- Volunteers
- 184 people
- Sponsor
- Changi General Hospital