Clinical trials: Polyp, Colonic
Colonic Polyps, Colorectal Adenomas
Impact of Automatic Polyp Detection System on Adenoma Detection Rate
In recent years, with the continuous development of artificial intelligence, automatic polyp detection systems have shown its potential in increasing the colorectal lesions.
- Trial name
- NCT03967756
- Testing
- Automatic polyp detection system
- Where
- China
- Volunteers
- 1,118 people
- Sponsor
- Changhai Hospital
Colon Polyp
Comparison of Polyp Detection and False Alarm Rates in Water Exchange and Air Insufflation Colonoscopy
Water exchange (WE) improves adenoma detection rate (ADR) but missed polyps occur due to human limitations. Computer-aided detection (CADe) improves polyp detection and can overcome human omissions, but a limiting factor is feces…
- Trial name
- NCT04727814
- Testing
- Computer-aided detection system overlaid colonoscopy videos analysis
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- Dalin Tzu Chi General Hospital
Polyp of Colon
The Non-Optical Resect and Discard Study (NORD)
Eliminating the need for conventional histopathological assessment of diminutive colon polyps - The Non-Optical Resect and Discard (NORD) study
- Trial name
- NORD (NCT04032912)
- Testing
- iScan
- Where
- Canada
- Volunteers
- 1,200 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Colonic Polyps
Cold Polypectomy Site Study
Removal of polyps at colonoscopy reduces colon cancer. Snare polypectomy is the conventional method for removal however the snared area after removal can occasionally appear uneven raising the possibility that complete removal…
- Trial name
- NCT02205125
- Where
- Australia
- Volunteers
- 88 people
- Sponsor
- Professor Michael Bourke
Colon Polyp, Endocuff
Adenoma Miss Rate in Tandem Endocuff-assisted Colonoscopy
Colonoscopy is a valuable tool in reducing the incidence and mortality from colorectal cancer (CRC). Older back-to-back studies evaluating novel endoscopes indicated that conventional colonoscopy misses almost 20% of adenomas.
- Trial name
- NCT04805567
- Testing
- endocuff
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Venizelio General Hospital
Colonic Polyp
Detection of Colonic Polyps Via a Large Scale Artificial Intelligence (AI) System
Colonoscopy is the gold standard for detection and removal of precancerous lesions, and has been amply shown to reduce mortality.
- Trial name
- NCT04693078
- Testing
- AI polyp detection system based on deep learning
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Colon Polyp, Colon Adenoma
Impact of Screen Size on Colorectal Adenoma Detection
The purpose of this study is to assess whether the use of large screen during colonoscopy will increase adenoma detection rate.
- Conditions
- Colon Polyp, Colon Adenoma, Colorectal Neoplasms
- Trial name
- NCT04749303
- Testing
- Large Screen
- Where
- Hong Kong
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colon Cancer
Screening and Risk Factors of Colon Neoplasia
The investigators propose a screening population-based study to systematically evaluate the accuracy and clinical relevance of sDNA testing as a potential alternative to colonoscopy screening.
- Trial name
- NCT01647776
- Testing
- Stool DNA Test, biopsies of rectal and colon mucosa, Questionnaires
- Where
- United States
- Volunteers
- 3,315 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Colonic Polyp, Colorectal Cancer
Study on Second Forward View Examination in the Right Colon
It is estimated that there are about 1.4 million patients with colorectal cancer (CRC) worldwide, with a rising trend in CRC incidence in many Asian Pacific countries.
- Trial name
- NCT03121495
- Testing
- Second forward view (SFV) examination of the right colon
- Where
- 3 sites in Hong Kong
- Volunteers
- 1,011 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colonic Polyp, Colonoscopy
CUFF-assisted Colonoscopy vs Standard Colonoscopy
The goal of this study is to evaluate the interest of second-generation Endocuff Vision (ECV) to improve Adenoma detection rate and / or Polyp detection rate in routine colonoscopy.
- Trial name
- CUFF-TROCADERO (NCT03758872)
- Testing
- cuff assisted colonoscopy(with cuff use of endocuff vision second generation)
- Where
- France
- Volunteers
- 1,034 people
- Sponsor
- Clinique du Trocadéro
Colorectal Cancer, Colon Polyp
Efficacy of Free Versus Low Residue Diet as Preparation for Screening Colonoscopy
One tricky aspect of the recommendations for colonoscopy prep is diet. This has a significant impact on the experience of the patient or participant in the screening program and, on the other hand, low adherence has been found in…
- Conditions
- Colorectal Cancer, Colon Polyp, Colon Adenoma
- Trial name
- CriLi (NCT04664543)
- Testing
- Free diet, Three days low residue diet
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Parc Taulí Hospital Universitari
ColoRectal Cancer, Colon Polyp
Withdrawal Time and Use of Wide-angle Endoscope to Increase the Adenoma Detection Rate of Screening Colonoscopy
Colonoscopy outcome is strictly related to the adenoma detection rate (ADR). An endoscopy withdrawal time >6min has been suggested to increase the ADR since it allows for thorough evaluation of the several hidden areas of the…
- Trial name
- NCT02985944
- Testing
- Colonoscopy
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- ASST Rhodense
Chronic Kidney Diseases, Colon Polyp
Low-volume vs High-volume Polyethylene Glycol Based Bowel Preparation for Colonoscopy in People Receiving Hemodialysis
Current American Society for Gastrointestinal Endoscopy (ASGE) and European Society of Gastrointestinal Endoscopy (ESGE) guidelines recommend a split regimen of high-volume (4-liter polyethylene glycol-based preparation) or…
- Conditions
- Chronic Kidney Diseases, Colon Polyp, Dialysis; Complications, Colon Cancer
- Trial name
- PrepDial (NCT04709770)
- Testing
- 2-liters polyethylene glycol with citrate and simethicone, 4-liters polyethylene glycol with simethicone, Low-residue diet
- Volunteers
- 264 people
- Sponsor
- Alfredo Di Leo
Colonic Polyp, Colonic Adenoma
Effectiveness of Using the Speedometer During Colonoscopy
PURPOSE OF PROTOCOL Objective: To evaluate if the speedometer based on the real-time image analysis can help endoscopists increase their withdrawal time, which is defined as time spent examining the colon during withdrawal of the…
- Conditions
- Colonic Polyp, Colonic Adenoma, Adenoma Colon
- Trial name
- NCT04710251
- Testing
- Speedometer
- Volunteers
- 332 people
- Sponsor
- Norwegian Department of Health and Social Affairs
Colon Polyps
A Pilot Randomized Trial of Polypectomy Techniques for 4-6 mm Colonic Polyps
Complete polypectomy is one of the major factors for effectiveness of colonoscopy to prevent colon cancer. Given the prevalence of the 4-6 mm polyp, and the concern about interval cancers at polypectomy sites, there is a clear…
- Trial name
- NCT04666194
- Testing
- Cold forceps, Cold snare, Hot snare
- Where
- 3 sites in United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colonic Polyp
Evaluation of a Double Balloon Interventional Platform (DiLumen) for Complex Colonic ESD
The purpose of this randomized study is to compare ESD procedural time and cost facilitated with a dual balloon accessory device versus ESD procedures performed without the accessory device.
- Trial name
- NCT03846609
- Testing
- double balloon interventional platform (DiLumen), no double balloon interventional platform (DiLumen)
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Mercy Medical Center
Colorectal Cancer, Adenomatous Polyps
Multitarget Stool FIT-DNA Study for Colorectal Cancer Early Screening in China
The primary objective is to determine the diagnostic sensitivity and specificity of the newly developed multitarget FIT-DNA Colorectal Cancer (CRC) screening test (ColoClear) for detecting advanced neoplasia (including colorectal…
- Conditions
- Colorectal Cancer, Adenomatous Polyps, Adenoma, Advanced Adenoma
- Trial name
- CLEAR-C (NCT04287335)
- Testing
- Multitarget stool FIT-DNA test - ColoClear, FIT, Colonoscopy
- Where
- 8 sites in China
- Volunteers
- 4,758 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Polyps of Colon
Prospective Study of a New Endolumenal Device Used During Endoscopic Polypectomy in the Colon
This prospective observational study will evaluate the performance of the DiLumen C2 Endolumenal Interventional Platform and its instruments. Up to 100 subjects will be enrolled at up to 5 clinical sites.
- Trial name
- DiLumenC2 (NCT04657601)
- Testing
- DiLumen C2 Endolumenal Interventional Platform
- Volunteers
- 100 people
- Sponsor
- Lumendi, LLC
Polyp of Colon
Pronostic Score of Morbidity to Determine Risk of Complications After Endoscopic Submucosal Dissection for Colorectal Lesions
The mains complications in colo-rectal dissection are the pain, the delayed bleeding and the perforation and represent around 10%.
- Trial name
- NCT04647266
- Testing
- endoscopic submucosal dissection
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Central Hospital, Nancy, France
Colon Polyp
Collecting Recorded Videos of Colonoscopy Tests
The study shall mainly help to better evaluate the performance the APDS device and secondly it may help to assess the potential of the future alpha version of the device to be a useful and effective for the detection of colon…
- Trial name
- NCT03937063
- Testing
- Collecting recorded videos of Colonoscopy screening tests
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD