Clinical trials: Polyp, Colonic
Polyps, Neoplasms
Advanced Endoscopic Imaging in Colonoscopy
The aim of the study is to evaluate the usefulness of high-tech endoscopy in clinical practice. The important elements of this evaluation are: Evaluation of the character of neoplastic lesions in the colon based on different…
- Trial name
- AEI (NCT02929381)
- Testing
- Innovative colonoscopy (Olympus CF-HQ190L, NBI + Dual Focus), Conventional colonoscopy (Olympus CF-H180DL)
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Miroslaw Szura
Colonic Polyp, Colorectal Adenoma
Clinical Trial Evaluating External Evaluation and Training on the Incomplete Resection (POLIPEVA Study)
Introduction It has been shown that some quality indicators in endoscopy can be improved through educational interventions. There are marked differences in the proportion of incomplete polypectomies among endoscopists.
- Conditions
- Colonic Polyp, Colorectal Adenoma, Colorectal Cancer
- Trial name
- POLIPEVA (NCT04636619)
- Testing
- Colonic polypectomy, Online training course
- Where
- Spain
- Volunteers
- 1,920 people
- Sponsor
- Hospital del Rio Hortega
Colon Adenoma, Colon Polyp
A Double Balloon Endoscopic Platform for ESD
The purpose of this observational study is to record performance of a double balloon endolumenal interventional platform during complex colon polypectomy.
- Trial name
- NCT03551379
- Testing
- Double Balloon Endoluminal Platform
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Lumendi, LLC
Colonic Polyps, Colorectal Neoplasms
Comparative Effectiveness of Hot Versus Cold Snare Polypectomy of Small Colorectal Polyps
This study aims to investigate the comparative effectiveness between polyp removal with or without electrical current. The investigators want to include 600 polyps in the trial.
- Conditions
- Colonic Polyps, Colorectal Neoplasms, Adenoma
- Trial name
- HOT/COLD (NCT02484079)
- Testing
- Polypectomy
- Volunteers
- 429 people
- Sponsor
- Sorlandet Hospital HF
Colon Polyps, Colon Cancer Screening
Right Sided Colon Polyp Miss Rate: Impact Of Retroflexion In The Right Colon
Colonoscopy is the gold standard screening test for colorectal cancer. Removal of pre-malignant colon polyps during colonoscopy reduces colorectal cancer mortality by over 50%.
- Trial name
- NCT01704820
- Testing
- Retroflexion in the right colon
- Where
- 2 sites in United States
- Volunteers
- 1,020 people
- Sponsor
- Washington University School of Medicine
Colonic Polyp
Use of the Napoleon to Improve Polyp Measurement in Gastroenterology Fellows
This is a clinical trial assessing gastroenterology fellows' accuracy of colonic polyp measurement using a Micro-Tech Endoscopic Polyp Measurement Device named Napoleon.
- Trial name
- NCT04858477
- Testing
- Visual estimation of polyp size, Napoleon measurement of polyp size
- Where
- 4 sites in United States
- Volunteers
- 46 people
- Sponsor
- NYU Langone Health
Colo-rectal Cancer
Motility of the Check-cap's MD1 Colon Capsule in Subjects Following Colon Rectal Cancer Screening by Colonoscopy
To monitor the Whole Gut Transit Time and repeatability of the motility of MD1 capsules in the colon of subjects with known polyps and in healthy subjects. Multi-Center, Open, Home Monitoring, Prospective Study.
- Trial name
- NCT03785665
- Testing
- MDI
- Where
- Israel
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Colonic Dysplasia, Adenomatous Polyps
Study of Performance of Confocal Endomicroscope With Fluorescein Imaging Agent in the Colon
The overall aim of this research project is to evaluate the imaging performance of a confocal endomicroscope. Fluorescein, an FDA-approved topical fluorescent dye, will be used to provide topical mucosal contrast.
- Conditions
- Colonic Dysplasia, Adenomatous Polyps, Irritable Bowel Disease
- Trial name
- NCT03220711
- Testing
- confocal endomicroscope, Fluorescein
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Michigan
Adenoma Colon, Colon Polyp
COmparison of White Light and Linked COlor Imaging for Detection of RIght COlon Polyps
Comparison of the number of adenomas missed by the first exploration of the right colon by LCI (linked color imaging) or by white light during a colonoscopy, according to the order of randomization.
- Conditions
- Adenoma Colon, Colon Polyp, Colonoscopy
- Trial name
- COCORICO (NCT04112563)
- Testing
- exploration in white light (WLI), Exploration in LCI
- Where
- France
- Volunteers
- 686 people
- Sponsor
- Société Française d'Endoscopie Digestive
Adenoma, Colo-rectal Cancer
Clinical Value of G-EYE Colonoscopy in Daily Practice for Adenoma Detection and Time for Polyp Removal
Colonoscopy parameters will be compared before the introduction of the G-EYE endoscope and after the introduction of the G-EYE endoscope
- Trial name
- NCT04767971
- Testing
- Standard Colonoscopy, G-EYE Colonoscopy
- Where
- Germany
- Volunteers
- 2,795 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Colorectal Cancer, Adenomatous Polyps
Exploratory Study of a Novel Based rbcDNA Liquid Biopsy Technique for Colorectal Cancer Early Detection
Exploration of a novel rbcDNA liquid biopsy technique for early detection of colorectal cancer is a promising development in the field of disease diagnosis and screening.
- Conditions
- Colorectal Cancer, Adenomatous Polyps, Adenoma, Advanced Adenoma
- Trial name
- NCT05875584
- Testing
- rbcDNA test
- Where
- China
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Colorectal Cancer
Polyp Measurement Device
Colorectal cancer is the second-leading cause of cancer death in the United States. Colorectal cancer screening is recommended to begin at age 50 years for most men and women at average risk for this disease.
- Trial name
- NCT03856255
- Testing
- Micro-Tech Endoscopic Gauge
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Colorectal Cancer
Clinical Validation of PolyDeep: an Artificial Intelligence-based Computer-aided Polyp Detection (CADe) and Characterization (CADx) System. Polydeep Advance 2.
This study is a clinical validation of PolyDeep, a computer-aided polyp detection (CADe) and characterization (CADx) system. PolyDeep Advance 2 is a multicentric randomized clinical trial with a tandem colonoscopy design.
- Trial name
- NCT05512793
- Testing
- Standard technique First colonoscopy without PolyDeep, Combination technique First colonoscopy with PolyDeep
- Where
- 3 sites in Spain
- Volunteers
- 260 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Familial Adenomatous Polyposis
Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)
Familial Adenomatous Polyposis (FAP) is an autosomal dominant disorder characterized by the formation of multiple adenomatous colorectal polyps usually in the teenage years.
- Trial name
- NCT00927485
- Testing
- Calcumin (Curcumin), Risk Factor Questionnaire, Blood samples
- Where
- Puerto Rico
- Volunteers
- 44 people
- Sponsor
- University of Puerto Rico
Colon Polyp
Evaluation of the DiLumen Device During Colonoscopy
This is an observational registry study collecting data on the clinical performance of the study device (DiLumen™ ) for its intended use. The primary objective is to evaluate functional outcomes of the DiLumen device in humans.
- Trial name
- NCT03113578
- Testing
- DiLumen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Lumendi, LLC
Colonic Polyps
Cold Polypectomy Site Study
Removal of polyps at colonoscopy reduces colon cancer. Snare polypectomy is the conventional method for removal however the snared area after removal can occasionally appear uneven raising the possibility that complete removal…
- Trial name
- NCT02205125
- Where
- Australia
- Volunteers
- 88 people
- Sponsor
- Professor Michael Bourke
Familial Adenomatous Polyposis (FAP)
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
The main goal of this clinical trial is to learn if the drug eRapa works to slow down the progression of disease in patients diagnosed with Familial Adenomatous Polyposis (FAP). Researchers will compare eRapa to Placebo.
- Trial name
- SERENTA (NCT06950385)
- Testing
- eRapa (encapsulated rapamycin)
- Where
- 29 sites in United States, Denmark and 5 more
- Volunteers
- 168 people
- Sponsor
- Rapamycin Holdings Inc.
KLF4 Methylation, Epigenetic
KLF4 Epigenetic Modulation
The study investigates the epigenetic regulation of KLF4 during the progression from colorectal polyps to adenomas and carcinomas.
- Trial name
- POLYEP (NCT07901335)
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Colonoscopy
A Clinical Validation Study of a Computerized Movement Analysis of the Colonoscope
Colonoscopy is the considered gold standard for diagnosing diseases in the colon. A colonoscopy is normally divided into the insertion from anus to cecum, the technical difficult part, and a retraction or diagnostic part.
- Trial name
- NCT03587935
- Testing
- 3D-Colonoscopy Progression Score, 3D-Colonoscopy Retraction Score
- Where
- Denmark
- Volunteers
- 9 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Colonic Polyp, Colon Lesion
Comparative Analysis of AI Software for Enhanced Polyp Detection and Diagnosis
Purpose \& Research Questions The purpose of this study is to evaluate whether artificial intelligence (AI) improves the detection of polyps and whether the system can classify the type and severity of detected changes.
- Trial name
- NCT06077435
- Testing
- AI
- Where
- Sweden
- Volunteers
- 915 people
- Sponsor
- Sahlgrenska University Hospital