Clinical trials: Polyp, Colonic
Gastrointestinal Disease, Inflammatory Bowel Diseases
Using Virtual Reality for Patients With Gastrointestinal Disease
The primary aim of this study is to evaluate the effect and impact of a technology which creates a virtual reality (VR), personalized representation of a patient's endoscopic findings in comparison our standard practice (SP).
- Trial name
- NCT03719209
- Testing
- HealthVoyager, Standard Practice
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
Diverticulitis, Colon Polyps
Early Post-Op Recovery After Partial Large Bowel Resection
The purpose of this trial is to gather information on the postoperative recovery time and hospital length of stay experienced by patients having laparoscopic surgeries.
- Conditions
- Diverticulitis, Colon Polyps, Colorectal Cancer
- Trial name
- NCT00492193
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- University Hospitals Cleveland Medical Center
Colon Cancer
Screening and Risk Factors of Colon Neoplasia
The investigators propose a screening population-based study to systematically evaluate the accuracy and clinical relevance of sDNA testing as a potential alternative to colonoscopy screening.
- Trial name
- NCT01647776
- Testing
- Stool DNA Test, biopsies of rectal and colon mucosa, Questionnaires
- Where
- United States
- Volunteers
- 3,315 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Colonic Polyps, Colon Neoplasms
Precision of Optical Diagnosis in Polyps Between 5-15 mm and Its Implications on Surveillance. A Prospective, Multicenter Study.
This study evaluates the ability of endoscopists to perform a complete optical diagnosis of colorectal polyps between 5 and 15 mm, and the impact of the only endoscopic diagnosis on the follow-up program for those patients.
- Conditions
- Colonic Polyps, Colon Neoplasms, Colon Cancer, Serrated Adenoma
- Trial name
- POPS (NCT04232176)
- Where
- Spain
- Volunteers
- 545 people
- Sponsor
- University Hospital Virgen de las Nieves
Colorectal Cancer
Celecoxib in Preventing Cancer in Patients With Rectal Polyps or Colorectal Neoplasia
RATIONALE: Celecoxib may be effective in preventing colorectal cancer in patients who have a history of rectal polyps or colorectal neoplasia.
- Trial name
- NCT00043043
- Testing
- celecoxib
- Where
- 2 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Artificial Intelligence, Enteroscope
A Clinical Trial of the Effectiveness and Safety of Software Assisting Diagnose the Intestinal Polyp Digestive Endoscopy by Analysis of Colonoscopy Medical Images From Electronic Digestive Endoscopy Equipment
A clinical trial of the effectiveness and safety of intestinal polyp digestive endoscopy-assisted diagnosis software used in the analysis of colonoscopy medical images generated by electronic digestive endoscopy equipment.
- Conditions
- Artificial Intelligence, Enteroscope, Intestinal Polyposis, Adenomatous
- Trial name
- NCT05687318
- Testing
- DeFrame
- Where
- China
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Colorectal Cancer, Colorectal Adenoma
The Colorectal Cancer Chemoprevention Acceleration and Improvement Platform (CRC-CHAMP) Study
The overall goal of this study is to develop a platform for both large-scale chemoprevention trials and real-world chemoprevention studies for colorectal cancer (CRC) prevention.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Colorectal Adenomatous Polyp
- Trial name
- NCT05402124
- Testing
- acetylsalicylic acid delayed release tablets, 81mg
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Colonic Polyps
Positioning During Colonoscopy
Colonoscopy is the gold standard investigation in the screening of colorectal neoplasms. The investigators hypothesise that visualisation of the colonic mucosa on extubation may be improved by changing patient position as…
- Trial name
- NCT01254435
- Testing
- Colonoscopy
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Colon Cancer, Polyps
Evaluation of Stool Tagging for Improved Patient Compliance
Computed tomography (CT) colonography has gained widespread multi-disciplinary interest as an evolving noninvasive colorectal screening examination, with the potential of improved patient compliance.
- Trial name
- NCT00124163
- Testing
- Imaging procedure of CT colonography
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Center for Diagnostic Imaging
Colonic Lesions
Prospective Image Collection of Colorectal Polyps.
It concerns a study in which we wish to collect images and corresponding histological information (microscopic characteristics) in a prospective manner in various European and non-European centers (multicentric).
- Trial name
- NCT07401264
- Where
- Belgium
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colon Adenoma
Computer-assisted Detection of Colonic Polyps
Screening colonoscopy is considered the gold standard for adenoma detection in the colon. However, it has been shown that a considerable number of polyps can be missed during screening colonoscopy.
- Trial name
- KoloPol I (NCT02838888)
- Testing
- Automatic polyp detection software
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich
Colonic Adenoma, Colon Polyp
Comparison of the Benefit of Chromoendoscopy in Addition to High Definition White Light and Narrow Band Imaging for the Prediction of Submucosal Invasive Cancer in Colonic Lesions
To compare the incremental benefit of chromoendoscopy in addition to high definition white light and narrow band imaging in predicting submucosal invasion within laterally spreading lesions in the colon and in determining the…
- Conditions
- Colonic Adenoma, Colon Polyp, Submucosal Invasive Colon Adenocarcinoma, Colorectal Cancer
- Trial name
- LANS (NCT03506321)
- Testing
- chromoendoscopy, high definition white light and narrow band imaging
- Where
- Australia
- Volunteers
- 400 people
- Sponsor
- Western Sydney Local Health District
Colon Polyp
Endocuff Vision Assisted vs. Standard Polyp Resection in the Colorectum
Adenomas are premalignant polyps of the colon that should be resected endoscopically. Complete resection of adenomatous polyps is the major task of colonoscopy.
- Trial name
- EVASTA (NCT03117114)
- Testing
- Endocuff Vision assisted polypectomy, Standard polypectomy
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Technical University of Munich
Colorectal Polyps
Effectiveness of Cold Biopsy Forceps With Pre-lift for Complete Resection of Colonic Polyps ≤7mm in Size
There is no consensus method for removal of diminutive (5mm) to small(6-9mm) colorectal polyps at colonoscopy. Neither the European Society of Gastrointestinal Endoscopy or the American Society of Gastrointestinal Endoscopy have…
- Trial name
- NCT02354287
- Testing
- Cold forceps polypectomy with pre lift
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Colonic Polyp
Computer Aided Diagnosis (CADx) for Colorectal Polyps Resect-and-Discard Strategy
Colonoscopic removal of adenomatous polyps reduce both the incidence and mortality of colorectal cancer (CRC). The common clinical management of colorectal polyp detected during colonoscopy is to remove them and send for…
- Trial name
- CADx (NCT06062095)
- Testing
- AI-powered computer-aided diagnosis (CADx)
- Where
- Hong Kong
- Volunteers
- 1,764 people
- Sponsor
- Chinese University of Hong Kong
Rectal Cancer, Colo-rectal Cancer
Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery
When a patient is diagnosed with a rectal (bowel) polyp or cancer, radiology doctors read MRI scans to describe how deeply the cancer invades into the bowel wall (this is the 'stage' of the cancer).
- Trial name
- PRESERVE (NCT04103372)
- Testing
- MRI scan, Radiologist training
- Where
- 23 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Imperial College London
Colonic Neoplasia
Computed Tomography (CT) Colonography Versus Optical Colonoscopy
This study is designed to compare traditional Colonoscopy with CT Colonography, commonly known as "virtual colonoscopy". The study will compare the ability of both procedures as screening tests to identify polyps in the colon in…
- Trial name
- NCT01181739
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Colorectal Cancer, Colon Polyps
Prevalence and Topography of Adenomas in 40-49 Year Old Patients With a Family History of Colon Cancer
Conflicting guideline recommendations for screening colonoscopy result due to scant data upon which to develop appropriate recommendations.
- Conditions
- Colorectal Cancer, Colon Polyps, Adenomatous Polyp of Colon
- Trial name
- NCT02289053
- Where
- 6 sites in United States
- Volunteers
- 1,623 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Colonoscopy, Colon Polyps
A Study of AQUAVAN® Injection in the Presence of Pre-Medication in Patients Undergoing Elective Colonoscopy
This study was designed to assess the safety and efficacy of AQUAVAN® Injection in providing adequate sedation in patients undergoing colonoscopy.
- Trial name
- NCT00209534
- Testing
- fospropofol disodium
- Volunteers
- 200 people
- Sponsor
- Eisai Inc.
Polyp of Colon
Clinical vAliDation of ARTificial Intelligence in POlyp Detection
This study is an open label, unblinded, non-randomized interventional study, comparing the investigational artificial intelligence tool with the current "gold standard": Data acquisition will be obtained during one scheduled…
- Trial name
- CAD-ARTIPOD (NCT04442607)
- Testing
- artificial intelligence image processing
- Where
- Belgium
- Volunteers
- 856 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven