Clinical trials: Polyp, Colonic
Colorectal Neoplasms, Digestive System Diseases
Multi-Target Colorectal Cancer Screening Test for the Detection of Colorectal Advanced Adenomatous Polyps and Cancer
The primary objective is to determine the sensitivity and specificity of the Exact Colorectal Cancer (CRC) screening test for colorectal cancer, using colonoscopy as the reference method.
- Conditions
- Colorectal Neoplasms, Digestive System Diseases, Colonic Diseases, Colorectal Cancer
- Trial name
- DeeP-C (NCT01397747)
- Where
- 184 sites in United States, Canada
- Volunteers
- 12,776 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Colorectal Polyp, Colorectal Neoplasms
Colonoscopy vs Stool Testing for Older Adults With Colon Polyps
This is a multi-site comparative effectiveness randomized controlled trial (RCT) comparing annual fecal immunochemical testing (FIT) and colonoscopy for post-polypectomy surveillance among adults aged 65-82 with a history of…
- Conditions
- Colorectal Polyp, Colorectal Neoplasms, Colorectal Adenoma, Colorectal Cancer
- Trial name
- COOP (NCT05612347)
- Testing
- FIT, Colonoscopy
- Where
- 24 sites in United States, Canada
- Volunteers
- 6,434 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Colonic Polyps
Circumferential Submucosal Incision Endoscopic Mucosal Resection Versus Conventional Endoscopic Mucosal Resection of Colonic Polyps
That Circumferential Submucosal Incision Endoscopic Mucosal Resection (CSI-EMR) will be at least as safe but more effective than conventional EMR for injection assisted EMR of large laterally spreading tumour and sessile polyps…
- Trial name
- CSIEMR (NCT01369316)
- Testing
- Circumferential Submucosal Incision Resection, Endoscopic Mucosal Resection
- Where
- Australia
- Sponsor
- Professor Michael Bourke
Obstructing Colorectal Cancer
Preoperative Assessment for Synchronous Carcinoma or Polyps With Magnetic Resonance (MR) Colonography
The purpose of this study is to diagnose possible synchronous carcinomas and polyps with magnetic resonance (MR) colonography in patients booked for operation because of carcinoma in the descending or sigmoid colon, where a…
- Trial name
- NCT00300547
- Testing
- MR colonography
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Herlev Hospital
Colon Polyp, Colon Neoplasm
Effect of Enhanced Interactive Text Messages and Phone Instruction on the Quality of Bowel Preparation for Colonoscopy.
Efficacy Evaluation of Enhanced Bowel Preparation Instructions in Elective Colonoscopy.
- Trial name
- NCT04898426
- Testing
- Enhanced bowel preparation instruction
- Where
- Australia
- Volunteers
- 500 people
- Sponsor
- Griffith Base Hospital
Colorectal Cancer
Is Barium Enema an Adequate Diagnostic Test for Patients With Positive FOBT?
The research protocol aim is to compare diagnostic tools for the proper evaluation of patient with fecal occult blood test positive (FOBT +), a routine screening test for colorecatl carcinoma.
- Trial name
- DCBE (NCT00619814)
- Testing
- Double-contrast Barium enema, colonoscopy
- Volunteers
- 50 people
- Sponsor
- VA Caribbean Healthcare System
Colorectal Neoplasms
ENDO-AID Assisted Tandem Colonoscopy RCT
This study hypothesizes that more adenomas will be detected using the ENDO-AID assisted Colonoscopy compared to conventional colonoscopy.
- Trial name
- NCT05013125
- Testing
- ENDO-AID CADe assisted Colonoscopy
- Where
- Hong Kong
- Volunteers
- 360 people
- Sponsor
- Chinese University of Hong Kong
Colonic Polyp
Characterization of Colorectal Neoplasia
This is a post-marketing, single-arm, prospective study investigating the use of GI Genius CADx device in the real-time characterization of colorectal polyps (i.e. prediction of their histology during the colonoscopy).
- Trial name
- CHANGE (NCT04884581)
- Testing
- GI Genius CADx device
- Where
- Italy
- Volunteers
- 165 people
- Sponsor
- Nuovo Regina Margherita Hospital
ColoRectal Cancer, Colonic Polyps
Feasibility of Check-Cap's P1 Capsule System Screening
Prospective, Single arm, Multi-Center 1. To establish the safety and preliminary efficacy of the Check-Cap System in patients with negative FOBT (Fecal Occult Blood Test) 2.
- Trial name
- NCT01458925
- Testing
- The P1 Check-Cap capsule
- Where
- Israel
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Adenoma Colon, Colorectal Cancer
Retrospective Evaluation of 3 Colonic Adenoma Detection Strategies
Retrospective study, single blind (patient), allowing a posteriori clinical data collection of 90 patients during their passage to the ambulatory endoscopy circuit, to consider 3 groups and thus to deduce a colonic adenoma…
- Conditions
- Adenoma Colon, Colorectal Cancer, Colorectal Polyp, Colonic Adenocarcinoma
- Trial name
- COLODETECT (NCT05080088)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Colon Polyp
A First-in-human Clinical Trial Evaluating a Novel Colonic Intraluminal Endoscopic Support Structure (CIESS)
The aim of the first-in-human clinical trial is to evaluate the feasibility of performing colonoscopic polypectomy with a novel colonic intraluminal endoscopic support structure (CIESS) in-situ
- Trial name
- NCT07311590
- Testing
- Colonic Intraluminal Endoscopic Support Structure
- Volunteers
- 4 people
- Sponsor
- JurongHealth
CRC Screening
Evaluation of Capsule Endoscopy With PillCam® COLON 2 in Visualization of the Colon
This study was design to establish the effectiveness of PillCam® Platform with the PillCam® COLON 2 capsule as demonstrated by the identification of subjects with polyps as compared to optical colonoscopy.
- Trial name
- NCT01372878
- Testing
- PillCam® COLON 2 procedure, Colonoscopy
- Where
- 17 sites in United States, Israel
- Volunteers
- 884 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Colonic Neoplasms, Colonic Adenocarcinoma
Assessing the Additional Neoplasia Yield of Computer-aided Colonoscopy in a Screening Setting
Even if colonoscopy is considered the reference standard for the detection of colonic neoplasia, polyps are still missed. The risk of early post-colonoscopy cancer appeared to be independently predicted by a relatively low…
- Conditions
- Colonic Neoplasms, Colonic Adenocarcinoma, Polyps of Colon, Rectal Neoplasms
- Trial name
- GENIAL-CO (NCT04441580)
- Testing
- CADe colonoscopy using GI Genius device
- Where
- Italy
- Volunteers
- 900 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Colorectal Cancer (CRC), Colorectal Cancer and Pre-cancer Polyps
Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria
The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria.
- Conditions
- Colorectal Cancer (CRC), Colorectal Cancer and Pre-cancer Polyps, Blood Stream Infection, Anaerobic Infection
- Trial name
- AB-care (NCT06919068)
- Testing
- Colon capsule endoscopy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Colonic Polyps
High Definition Endoscopy With i-Scan for Small Colonic Polyp Evaluation: The HiScope Study
Current standard practice is to remove all colonic polyps found during colonoscopy as it has not been possible to distinguish between polyps with some malignant potential (adenomatous) and those with negligable malignant…
- Trial name
- HiSCOPE (NCT01761279)
- Testing
- High definition white light endoscopy
- Volunteers
- 84 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Colon Adenoma, Colon Polyp
St. Paul's Advanced Resection Center Cohort for Colorectal Neoplasia (SPARC-C)
The SPARC-C study is a prospective, multi-institutional observational study of patients referred for the management of large (≥ 20mm) non-pedunculated colorectal polyps (LNPCPs).
- Conditions
- Colon Adenoma, Colon Polyp, Colon Lesion
- Trial name
- SPARC-C (NCT05402696)
- Testing
- Endoscopic tissue resection
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 3,500 people
- Sponsor
- University of British Columbia
Colorectal Cancer, Precancerous Condition
Improving the Frequency of Colonoscopy in Patients With a Previous Colorectal Polyp
RATIONALE: Receiving a reminder letter from their doctor may increase the frequency of colonoscopy in patients who have had a colorectal polyp removed.
- Trial name
- NCT00397969
- Testing
- counseling intervention, screening colonoscopy
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Colonic Polyp, Adenoma Colon
Accuracy of CADx System for White Light Colonic Polyp Characterization
The endoscopist performances in the optical diagnosis (OD) of colonic polyps with the available technologies vary widely across centers and across endoscopists.
- Trial name
- GIC (NCT05492656)
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Valduce Hospital
Colon Adenoma, Colon Polyp
A Double Balloon Endoscopic Platform for ESD
The purpose of this observational study is to record performance of a double balloon endolumenal interventional platform during complex colon polypectomy.
- Trial name
- NCT03551379
- Testing
- Double Balloon Endoluminal Platform
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Lumendi, LLC
Polyp Colorectal, Adenoma Colon
AI Colorectal Polyp Detection
This study is intended to demonstrate the superiority of colorectal polyp detection using computer-assisted colonoscopy compared to conventional colonoscopy.
- Trial name
- NCT04979962
- Testing
- EW10-EC02 (Endoscopy Support Program)
- Where
- 10 sites in United States
- Volunteers
- 1,162 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.