Clinical trials: Polyp, Colonic
Recurrence
Post-resection Treatment of Large Colon Polyps
Patients who have provided informed consented and are scheduled to undergo endoscopic mucosal resection (EMR) of lesions 15mm and larger will be randomized to STSC (80 W, Effect 5) vs APC (preferred settings) vs No Treatment of…
- Trial name
- SAP (NCT03654209)
- Testing
- Argon Plasma Coagulation, Snare Tip Soft Coagulation
- Where
- 10 sites in United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colorectal Neoplasms
Third Eye Retroscope Randomized Clinical Evaluation
The Third Eye® Retroscope® is a device that can be inserted through the instrument channel of a standard colonoscope to provide an additional, retrograde (or backward) view that reveals areas behind folds and flexures in the…
- Trial name
- TERRACE (NCT01044732)
- Testing
- Third Eye Retroscope
- Where
- 9 sites in United States, Belgium and 3 more
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Avantis Medical Systems
Familial Adenomatous Polyposis (FAP), Pouches, Ileoanal
Evaluation of the Ileo-anal Pouch in FAP (ENDOPOL)
This international, multi-centre randomised controlled trial will compare dye-based chromoendoscopy with virtual chromoendoscopy, using NBI/BLI, for adenoma detection during routine surveillance pouchoscopy in adults with…
- Trial name
- ENDOPOL (NCT07726771)
- Testing
- Chromoendoscopy (Indigo Carmine), Virtual Chromoendoscopy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- London North West Healthcare NHS Trust
Colonic Polyps
Cold Polypectomy Site Study
Removal of polyps at colonoscopy reduces colon cancer. Snare polypectomy is the conventional method for removal however the snared area after removal can occasionally appear uneven raising the possibility that complete removal…
- Trial name
- NCT02205125
- Where
- Australia
- Volunteers
- 88 people
- Sponsor
- Professor Michael Bourke
Obstructing Colorectal Cancer
Preoperative Assessment for Synchronous Carcinoma or Polyps With Magnetic Resonance (MR) Colonography
The purpose of this study is to diagnose possible synchronous carcinomas and polyps with magnetic resonance (MR) colonography in patients booked for operation because of carcinoma in the descending or sigmoid colon, where a…
- Trial name
- NCT00300547
- Testing
- MR colonography
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Herlev Hospital
Colon Polyp, Colon Adenoma
Impact of Screen Size on Colorectal Adenoma Detection
The purpose of this study is to assess whether the use of large screen during colonoscopy will increase adenoma detection rate.
- Conditions
- Colon Polyp, Colon Adenoma, Colorectal Neoplasms
- Trial name
- NCT04749303
- Testing
- Large Screen
- Where
- Hong Kong
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colon Adenoma, Colorectal Carcinoma
Accuracy of the Optical Diagnosis of Small Colonic Polyps Using the Nice Classification
Adenomas and hyperplastic polyps are polypoid lesion and may occur at any location in the colon. At the present moment, all polyps should be resected endoscopically, although only adenomas, but not hyperplastic polyps have the…
- Conditions
- Colon Adenoma, Colorectal Carcinoma, Hyperplastic Polyp
- Trial name
- ADOPTION (NCT02009774)
- Testing
- NBI Function
- Where
- 3 sites in Germany
- Volunteers
- 380 people
- Sponsor
- Technical University of Munich
Colonic Polyps
Efficacy and Safety of Precut-EMR for Resecting of Colonic Polyp
This study was attempted to determine the efficacy and complication of precut EMR comparing with convetional EMR for resecting of 10 ~ 20 mm colon polyp through prospective, randomized controlled trial.
- Trial name
- NCT04253990
- Testing
- Precut EMR, Conventional MER
- Where
- South Korea
- Sponsor
- Asan Medical Center
Colorectal Adenoma, Colorectal Polyp
Examining Techniques on Adenoma Miss Rate in Proximal Colon
The primary aim of this study is to explore the usefulness of re-examination and retroflexion on adenoma miss rate (AMR) in the proximal colon.
- Trial name
- SINOCOLO2017 (NCT03355443)
- Testing
- Retroflexion, Re-examination
- Where
- 3 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Neoplasms, Colorectal Cancer
Microbiome Test for the Detection of Colorectal Polyps and Cancer
The purpose if this study is to measure the sensitivity, specificity and accuracy of the Metabiomics Colon Polyp and Colorectal Cancer Assay for the non-invasive detection of colon polyps or colorectal cancer.
- Trial name
- NCT02141945
- Where
- 2 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Metabiomics Corp
Familial Adenomatous Polyposis (FAP)
A Safety Study of ST316 in Participants With Familial Adenomatous Polyposis (FAP).
This is a Phase 1b, open- label, dose-optimization study evaluating ST316 in adult participants with familial adenomatous polyposis (FAP) who have undergone colectomy and have recurrent polyps.
- Trial name
- FAP (NCT07729371)
- Testing
- ST316 IV
- Volunteers
- 40 people
- Sponsor
- Sapience Therapeutics
Colorectal Polyps
Discard:Characterisation of Colonic Polyps in Vivo
Prospective study of accuracy of colonic polyp characterisation in vivo using high resolution white light endoscopy, narrow band imaging and chromoendoscopy.
- Trial name
- DISCARD (NCT00888771)
- Where
- United Kingdom
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Colonic Polyp
DeFect cLOsure After Colonic ESD With underwaTer Technique
This is a single centre randomised controlled study comparing underwater clip closure versus conventional gas insufflation clip closure of post-resection defect in patients undergoing colonic endoscopic resection.
- Trial name
- FLOAT (NCT04214678)
- Testing
- Underwater clip closure, Conventional clip closure
- Where
- Hong Kong
- Volunteers
- 64 people
- Sponsor
- Chinese University of Hong Kong
Colorectal Neoplasms, Colitis, Ulcerative
Post-Op Quality of Life After Colorectal Surgery
The purpose of this study is to produce a user-friendly tool- in the form of a questionnaire - to accurately assess early quality of life in patients after abdominal colorectal surgery from the first day after surgery to 6 months…
- Conditions
- Colorectal Neoplasms, Colitis, Ulcerative, Diverticulitis, Colonic Polyps
- Trial name
- NCT00468455
- Testing
- Laparoscopic or open colorectal surgery
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University Hospitals Cleveland Medical Center
Familial Adenomatous Polyposis (FAP)
Efficacy of Vitamin B1 in Familial Adenomatous Polyposis Patients.
This study aimed to investigate the efficacy of vitamin B1 in patients with familial adenomatous polyposis, and to determine the inhibitory effect of vitamin B1 on the size and number of colorectal adenomas by administering oral…
- Trial name
- VitB1; FAP (NCT06649825)
- Testing
- Vitamin B1
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shanghai Zhongshan Hospital
Colonic Polyp
Real Life AI in Polyp Detection
The objective of this study is to compare the polyp detection rate (PDR) of endoscopists unaware of a commercially available artificial intelligence (AI) device for polyp detection during colonoscopy and the PDR of endoscopists…
- Trial name
- RELIANT (NCT04335318)
- Testing
- AI-assisted colonoscopy
- Where
- Germany
- Volunteers
- 230 people
- Sponsor
- Wuerzburg University Hospital
Colorectal Cancer
High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of folic acid may be an effective way to prevent colorectal cancer in patients with polyps that…
- Trial name
- NCT00002650
- Testing
- folic acid
- Where
- 8 sites in United States
- Volunteers
- 80 people
- Sponsor
- Eastern Cooperative Oncology Group
Colonic Polyps, Cancer Colon
Evaluation of Reduced-volume PEG Bowel Preparation Administered the Same Day of Colonoscopy
The conventional total dose of 4 L of polyethylene glycol (PEG) given the day before the procedure is safe and effective. It has been the standard cleansing regimen for the last 25 years.
- Conditions
- Colonic Polyps, Cancer Colon, Inflammatory Bowel Disease
- Trial name
- LowVolumePEG (NCT01533090)
- Testing
- polyethylene glycol (PEG), PEG low volume with bisacodyl
- Where
- Italy
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Colon Polyp
The Study of Adenoma Characteristics of the COX-2 and DNMT Expressions in the Index Colonoscopy to Predict the Polyp Recurrence During Surveillance
The colorectal cancer is the first incidence and ranks the third cancer-death cause in Taiwan. Based on the Taiwan-national colon cancer screening program, early colorectal cancer detection rate and the survival are markedly…
- Trial name
- NCT05568810
- Volunteers
- 831 people
- Sponsor
- National Cheng-Kung University Hospital
Polyps, Adenoma Colon
Computer Assisted Selection of Serrated Adenomas and Neoplastic Polyps - a New Clinical DRAft
The aim of the study is to develop a computer program which is able to classify different entities of colorectal polyps on the basis of optical polyp features.
- Conditions
- Polyps, Adenoma Colon, Automatic Judgement, Colonic Neoplasms
- Trial name
- CASSANDRA I (NCT03550625)
- Testing
- Computer program
- Volunteers
- 300 people
- Sponsor
- Technical University of Munich