Clinical trials: Polyps of Colon
Colonic Polyps
Artificial Intelligence in the Characterization of Colorectal Polyps
Current guidelines recommend resection and histopathological analyses of all colorectal polyps. Real-time optical diagnosis can obviate non-neoplastic polyp resection ("diagnose-and-leave-behind") and histopathological analyses…
- Trial name
- NCT04749277
- Testing
- CAD EYE® (Fujifilm, Europe, Gesellschaft mit beschränkter Haftung, Dusseldorf, Germany)
- Where
- Portugal
- Volunteers
- 197 people
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Subjects Will Have a Pre-cancerous Colorectal Polyp, Family Member Has History of Colorectal Adenoma of Adenocarcinoma
Effect of Folate on Colon and Blood Cells
This study looks at the effect of folate supplementation and depletion on the blood cells and the colorectal cells. To examine the effect of these changes, blood samples and colorectal biopsy samples are collected.
- Trial name
- NCT00220012
- Testing
- Folate depletion and supplementation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Quality of Bowel Preparation for the Colon Capsule, Colon Capsule Completion Rates
Improving Bowel Preparation for the Colon Capsule
Colon capsule endoscopy is a technology that has been developed as a noninvasive method of examining the large bowel. The biggest limitation to its use has been finding a bowel preparation that will both clean the colon…
- Conditions
- Quality of Bowel Preparation for the Colon Capsule, Colon Capsule Completion Rates, Colon Capsule Polyp Detection
- Trial name
- NCT01655095
- Testing
- PEG, Prucalopride, Picosalax
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen's University
Colon Cancer, Colon Polyp
Performance of Artificial Intelligence in Colonoscopy for Right Colon Polyp Detection
The aim of the study is to assess whether the use of artificial intelligence improves polyp detection in a segment of the colon (the right colon).
- Conditions
- Colon Cancer, Colon Polyp, Colon Lesion, Colon Adenocarcinoma
- Trial name
- AIRCOP (NCT06216405)
- Testing
- Colonoscopy
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Colonic Polyp
Accuracy of aCETIC Acid to Predict Histopathology of Colonic Polyps
The use of acetic acid in the characterization of polyps, produces a homogeneous white staining in sessile serrated adenomas, but not in tubular or tubulo-villous adenomas, a simple approach to predict polyp histopathology.
- Trial name
- Acetic (NCT04157803)
- Testing
- Acetic acid % spray
- Where
- Argentina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Aleman
Colorectal Cancer, Colorectal Adenoma
Comparison of Expression of Carcinogenesis-related Molecular Markers in the Patients With Colon Cancer and Polyp
A study of carcinogenesis-related molecular markers in the patients with colorectal cancer and colorectal adenoma.
- Trial name
- NCT05638542
- Where
- South Korea
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Colonic Polyp
Trainee Participation Increases Colon Adenoma Detection Rate
Previous studies that examined whether the presence of an additional observer, more specifically a GI fellow, during colonoscopy can enhance detection of all polyps and adenomas yielded conflicting results.
- Trial name
- ADR (NCT03908229)
- Testing
- Trainee colonoscopy, Experienced physician colonoscopy
- Where
- 4 sites in Italy
- Volunteers
- 812 people
- Sponsor
- Ospedali Riuniti di Foggia
Colonic Neoplasms, Colonic Polyp
Effectiveness of Artificial Intelligence - Assisted Colonoscopy in Colorectal Neoplasms
The primary goal of this study is to estimate the effectiveness of a medical decision support system based on artificial intelligence in the endoscopic diagnosis of benign tumors.
- Conditions
- Colonic Neoplasms, Colonic Polyp, Diagnosis
- Trial name
- ArtInCol (NCT06469671)
- Testing
- The system based on real - time artificial intelligence - assisted for colonoscopy
- Where
- Russia
- Volunteers
- 1,000 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Adenomatous Polyposis Coli
Influence of Sulindac and Probiotics on the Development of Pouch Adenomas in Patients With Familial Adenomatous Polyposis
The purpose of this study is to determine whether sulindac and VSL#3 - inulin, either combined or alone, are effective in treating or preventing adenoma development in the ileal anal pouch in patients with familial adenomatous…
- Trial name
- NCT00319007
- Testing
- Sulindac (drug), VSL#3 (probiotic), Inulin (probiotic)
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Colorectal Cancer
Real-Time Characterizations of Diminutive Colorectal Polyps Using Narrow Band Imaging
Colorectal cancer is the second leading cause of cancer related death in the United States. Colonoscopy is the most commonly performed screening procedure and diminutive polyps (<5mm) are the most commonly found polyps during…
- Trial name
- NCT02441998
- Testing
- Education intervention: Training in Narrow Band Imaging
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Neoplasms, Colorectal
Endoscopic Mucosal Resection Versus Endoscopic Submucosal Dissection for Colorectal Laterally Spreading Lesions.
EMR and ESD are both effective and safe and are associated with a very low risk of procedure related mortality when performed for colorectal laterally spreading lesions (LSL).
- Trial name
- intERsection (NCT04593407)
- Testing
- Endoscopic mucosal resection (EMR), Endoscopic submucosal dissection (ESD)
- Where
- Spain
- Volunteers
- 236 people
- Sponsor
- José Carlos Marín Gabriel
Colonic Polyp, Colonic Adenoma
Nationwide Study of Artificial Intelligence in Adenoma Detection for Colonoscopy
The goal of this trial is to determine whether use of a Computer Assisted Detection (CADe) programme leads to an increase in ADR for either units or individual colonoscopists, independent of setting or expertise
- Conditions
- Colonic Polyp, Colonic Adenoma, Colo-rectal Cancer
- Trial name
- NAIAD (NCT05870332)
- Testing
- GI Genius (GIG)
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Colorectal Neoplasms, Adenoma Colon
Surveillance Intervals After Piecemeal Resection of Non-pedunculated Colorectal Lesions ≥20mm
Intensive endoscopic surveillance following piecemeal resection of non-pedunculated colorectal lesions (NPCL) ≥20 mm is the current standard of care, given the high recurrence rate of these lesions (15-30%).
- Conditions
- Colorectal Neoplasms, Adenoma Colon, Colonic Polyps, Serrated Adenoma
- Trial name
- NCT06791616
- Testing
- Colonoscopy
- Volunteers
- 746 people
- Sponsor
- Asociación Española de Gastroenterología
Colon Adenoma, Colon Polyp
The Australian Colonic Large Sessile Lesion Endoscopic Resection Study
A prospective, multicentre, observational study of all patients referred for endoscopic resection of sessile colorectal polyps sized ≥20 mm conducted with intention to treat analysis
- Trial name
- ACE (NCT03471793)
- Where
- Australia
- Volunteers
- 5,000 people
- Sponsor
- Western Sydney Local Health District
Right Colon Adenoma Miss Rate, Right Colon Hyperplastic Polyp Miss Rate
Right Colon Polyp Miss Rates of Water Exchange and Carbon Dioxide Insufflation Colonoscopy
This will be a prospective randomized controlled trial comparing CO2 insufflation and WE in terms of right colon combined adenoma miss rate (AMR) and hyperplastic polyp miss rate (HPMR) by tandem inspection.
- Trial name
- NCT03845933
- Testing
- Colon polypectomy
- Where
- Taiwan
- Volunteers
- 262 people
- Sponsor
- Evergreen General Hospital, Taiwan
Colorectal Neoplasms, Gastrointestinal Microbiome
Predicting Adenomatous Polyps in the Colon Using Images of a Human Tongue
This is a prospective, multicenter, single-arm clinical investigation designed to evaluate the accuracy of the Gixam™ System in identifying subjects with colorectal adenomas compared to optical colonoscopy.
- Trial name
- NCT06305364
- Testing
- Gixam
- Where
- 3 sites in United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Jubaan Ltd.
Colonic Polyps, Surveillance
Large Overuse of Post-polypectomy Surveillance Colonoscopy
In colorectal cancer screening era a huge burden of medical resources has been applied to surveillance. Although the adherence to post-polipectomy recommendations is a advocated as a mainstay for quality assurance colonoscopy…
- Conditions
- Colonic Polyps, Surveillance, Colonoscopy
- Trial name
- NCT01458093
- Testing
- colonoscopy
- Where
- Italy
- Volunteers
- 7,081 people
- Sponsor
- Valduce Hospital
Colon Cancer
Screening and Risk Factors of Colon Neoplasia
The investigators propose a screening population-based study to systematically evaluate the accuracy and clinical relevance of sDNA testing as a potential alternative to colonoscopy screening.
- Trial name
- NCT01647776
- Testing
- Stool DNA Test, biopsies of rectal and colon mucosa, Questionnaires
- Where
- United States
- Volunteers
- 3,315 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Colonic Polyps
Cold Polypectomy Site Study
Removal of polyps at colonoscopy reduces colon cancer. Snare polypectomy is the conventional method for removal however the snared area after removal can occasionally appear uneven raising the possibility that complete removal…
- Trial name
- NCT02205125
- Where
- Australia
- Volunteers
- 88 people
- Sponsor
- Professor Michael Bourke
Colo-rectal Cancer, Cancer Colon
AI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening Test
Freenome is using a type of artificial intelligence, called machine learning, to identify patterns of cell-free biomarkers in blood to detect cancer early.
- Conditions
- Colo-rectal Cancer, Cancer Colon, Cancer, Rectum, Neoplasms,Colorectal
- Trial name
- NCT03688906
- Where
- 30 sites in United States, Canada
- Volunteers
- 3,275 people, healthy volunteers welcome
- Sponsor
- Freenome Holdings Inc.