Clinical trials: Port Wine Stains
Port-Wine Stain
Postmarketing Safety Study of Hemoporfin in Patients With Port Wine Stain
This study is to provide safety information of hemoporfin during the post-marketing period as required by China Food and Drug Administration (CFDA) regulations in order to identify any potential drug related treatment factors in…
- Trial name
- NCT03181984
- Testing
- Hemoporfin
- Where
- 7 sites in China
- Volunteers
- 501 people
- Sponsor
- Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
Port-Wine Stain
Novel Treatment for Port Wine Stain Birthmarks
Port wine stains Birthmark are congenital, progressive vascular malformations of the skin that occur in approximately 0.7% of newborns.
- Trial name
- NCT01924273
- Testing
- Talaporfin sodium
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of California, Irvine
Port Wine Stain
A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.
The researchers want to collect data on safety and efficacy of combined pulsed dye laser and rapamycin to improve fading/blanching of port wine stain birthmarks as compared to pulsed dye laser alone, which is the current standard…
- Trial name
- NCT00830466
- Testing
- Laser and rapamycin versus laser alone
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Irvine
Port Wine Stain
A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.
The purpose of this study is to improve port wine stain therapeutic outcome in response to laser therapy. The researchers want to determine whether the combined use of pulsed dye laser therapy and rapamycin will improve PWS…
- Trial name
- NCT00800722
- Testing
- Rapamycin Treatment of Port Wine Stain
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of California, Irvine
Port-wine Stain
A Pilot Study of Hemoporfin PDT in Children(2-7 Years Old) With Port-wine Stain
This pilot study aims to evaluate the safety and efficacy of hemoporfin photodynamic therapy (PDT) with different light doses for port-wine stain (PWS）in 2-7 years old children.
- Trial name
- NCT04106258
- Testing
- Hemoporfin PDT
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
Port Wine Stain
Combining Topical Imiquimod 5% Cream With a Pulsed Dye Laser to Treat Port Wine Stain Birthmarks
Port wine stains are red birthmarks that without treatment persist for a lifetime. They are frequently found on the face and can be conspicuous and disfiguring, negatively impacting social interactions for these patients.
- Trial name
- Aldara (NCT00585247)
- Testing
- Imiquimod
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Irvine
Port-Wine Stain
Combined Bipolar Radiofrequency&Pulsed Dye Laser Treatment
Port wine stain Birthmark is a congenital, progressive vascular malformation of human skin. However, even though the pulsed dye laser is considered as the treatment of choice for Port wine stain Birthmark the degree of fading can…
- Trial name
- NCT01775722
- Testing
- Pulsed Dye Laser, Combined Bipolar Radiofrequency&Pulsed Dye Laser
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Irvine
Port Wine Stains
Lip Reduction Surgery for Port-wine Macrocheilia
Patients with port-wine stains often develop macrocheilia, however, there is currently no effective treatment to significantly reduce the three-dimensional volume increase of the lips.
- Trial name
- macrocheilia (NCT07128459)
- Testing
- The Five-Step lip reduction surgery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Port Wine Stain
Combined Alexandrite and Pulsed Dye Laser Treatment of Port Wine Stain Birthmarks
Port wine stain is a congenital, progressive vascular malformation of skin involving post-capillary venules that occurs in an estimated 4 children per 1,000 live births.
- Trial name
- NCT00580944
- Testing
- laser treatment of port wine stain birthmarks
- Sponsor
- University of California, Irvine
Capillary Malformations
Onreltea (Brimonidine) Gel In Pediatric Patients With Capillary Malformations
Capillary Malformations (CM) affect a significant proportion of otherwise healthy children and may lead to psychological discomfort if left untreated.
- Trial name
- NCT02764411
- Testing
- Brimonidine 0.33% gel
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- The Hospital for Sick Children
Port Wine Stain
Personalized Interactive Laser Therapy of Port Wine Stain
Lasers are being used to treat Port Wine Stains (PWS), but the laser doesn't always work. Only about 10% of PWS can be completely cleared.
- Trial name
- NCT00782483
- Testing
- ThermoVision A20M Infrared Camera, ScleroPLUS, 3D Digital Camera
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Arkansas
Telangiectases, Port Wine Stain
Evaluation and Optimization of the Technical and Clinical Performance of the Lumenis ONE Platform
The Intense Pulsed Light (IPL) technology, by selective phototermolysis, is used for eliminating, among other application, benign vascular lesions and unwanted leg veins. Light energy heats the deeper structures of the skin.
- Trial name
- NCT00247299
- Testing
- IPL Quantum Product manufactured by Luminis Ltd.
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Capillary Malformation, Port Wine Stain
Effect of Laser Treatment on Capillary Malformations
In this research study investigators want to learn more about capillary malformations which are also known as port wine stains. Investigators are asking children with capillary malformations (port wine stains) to be in the…
- Trial name
- NCT02035319
- Where
- United States
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Port-Wine Stain
Retrospective Cohort Study on the Impact of PDL Treatment History on the Efficacy of HMME-PDT in Treating PWS Children
This retrospective study investigated the influence of prior pulse dye laser (PDL) treatment on the effectiveness of Hemoporfin-PDT in young children aged 1-3 years with PWS.
- Trial name
- NCT06875492
- Testing
- HMME-PDT, PDL
- Where
- China
- Volunteers
- 273 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Port Wine Stains
Maximizing Laser Therapy Success for Port-Wine Birthmarks in Pediatric Patients
In this study the investigators aim to optimize Port-Wine-Birthmark (PBW) laser therapy in children in order to reduce the number of laser treatments required for clearance and improve outcomes for refractory cases.
- Trial name
- NCT07183644
- Testing
- Pulse Dye laser, Pulse Dye Laser (PDL) pulse width stacking, Pulse Dye Laser (PDL) followed by Nd:YAG (Neodymium-doped Yttrium Aluminum Garnet laser) laser.
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Texas Southwestern Medical Center
Acceptance of Visible Chronic Dermatological Disease, Disease Acceptance
Measure of Acceptance of chRonic Visible sKin conditionS
The objective of this protocol is to validate 4 scales for evaluating the acceptance of visible chronic dermatological diseases (port wine stains, alopecia areata, vitiligo, hyperpigmentation...) with a large number of patients…
- Conditions
- Acceptance of Visible Chronic Dermatological Disease, Disease Acceptance, Psychological Well-Being, Social Segregation
- Trial name
- MARKS (NCT06103903)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Tours
Port Wine Stains
Port Wine Stains Treatment Matrix RF Study
The purpose of this study is to evaluate the efficacy and safety of the Matrix RF for Port Wine Stains based on clinical and histological analyses.
- Trial name
- NCT01101360
- Testing
- Matrix RF, Matrix RF followed by Pulse Dye Laser, Pulse Dye Laser followed by Matrix RF
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Syneron Medical
Port Wine Stain
Optical Frequency Domain Imaging (OFDI) in Dermatology
This is a pilot exploratory study. The goal of this study is to evaluate a new imaging tool, optical frequency domain imaging (OFDI), to reveal the microvascular morphology of capillary malformations.
- Trial name
- NCT01438047
- Where
- United States
- Sponsor
- Massachusetts General Hospital
PORT WINE STAIN
Monitoring the Response of Port Wine Stain Birthmarks to Laser Therapy With Wide-field Functional Imaging Technologies
The researcher develop non-invasive imaging modalities for assessment of port wine stain during laser therapy treatment of Port Wine Stain.
- Trial name
- NCT01333553
- Testing
- Image-guided remove Port Wine Stain
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of California, Irvine
Port-Wine Stain
Treatment of Naevus Flammeus Using Intense Pulsed Light and Pulsed Dye Laser
The purpose of the trial is to compare efficacy and adverse effects of pulsed dye laser and intense pulsed light in patients with port wine stains.
- Trial name
- NCT00365118
- Testing
- Pulsed dye laser (Candela), Intense pulsed light (Palomar)
- Where
- Denmark
- Sponsor
- Bispebjerg Hospital