Clinical trials: Portal Systemic Shunt
Portal Hypertension
Electromagnetic Positioning-Assisted Ultrasound Guidance in Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Transjugular intrahepatic portosystemic shunt (TIPS) is an important method for treating complications related to portal hypertension. The difficulty of its surgical procedures lies in portal vein puncture.
- Trial name
- NCT06979622
- Testing
- ultrasound combined with electromagnetic positioning guidance
- Volunteers
- 20 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Cirrhosis
Feasibility of Critical Flicker Frequency Procedure for the Diagnosis of Minimal Encephalopathy
All patients eligible for TIPS (Transjugular intrahepatic portosystemic shunt) procedure will be considered for inclusion. After written inform consent, psychometric tests in order to calculate the psychometric hepatic…
- Trial name
- NCT01080144
- Testing
- Critical flicker frequency procedure
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Portopulmonary Hypertension, Pulmonary Arterial Hypertension (PAH)
Genetic Hallmarks of Patients With Congenital Portosystemic Shunts and Portopulmonary Hypertension
Congenital portosystemic shunt (CPSS) are rare vascular malformations causing blood from the intestines to bypass the liver and directly flow into body's general circulation.
- Conditions
- Portopulmonary Hypertension, Pulmonary Arterial Hypertension (PAH), Congenital Portosystemic Shunt
- Trial name
- Gen-PoPH-CPSS (NCT07314814)
- Testing
- targeted gene panels analysis, whole genome analysis
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prof. Valérie Mc Lin
Liver Cirrhosis, Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Magnetic Resonance Technics for the Assessment of Liver Function Before and After TIPS
Portal hypertension is the end-stage fatal complications of liver cirrhosis. Decompensated cirrhosis patients can pass through transjugular intrahepatic portosystemic shunt to effectively prevent bleeding and refractory ascites.
- Conditions
- Liver Cirrhosis, Transjugular Intrahepatic Portosystemic Shunt (TIPS), Functional Magnetic Resonance Imaging
- Trial name
- NCT03933891
- Testing
- TIPS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- West China Hospital
Esophageal and Gastric Varices, Liver Cirrhosis
Decompression Intervention of Variceal Rebleeding Trial (DIVERT)
The Decompression Intervention of Variceal Rebleeding Trial (DIVERT) is a multi-center prospective randomized clinical trial comparing the radiologic procedure of transjugular intrahepatic portal-systemic shunt (TIPS) with the…
- Trial name
- NCT00006161
- Testing
- Transjugular Intrahepatic Portosystemic Shunt (TIPS), Distal Splenorenal Shunt
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Cirrhotic Portal Hypertension
PTFE Covered Stents Versus Naked Stents in the TIPS (Transjugular Intra-hepatic Porto-systemic Shunt)
Transjugular intrahepatic portosystemic shunts (TIPS) have been increasingly used for the treatment of complications of portal hypertension in patients with cirrhosis.
- Trial name
- NCT00593528
- Testing
- Naked Stents: Wallstent® (Boston Scientific), Luminexx® (Bard), Zilver® (Cook), Palmaz Genesis® and Smart Control® (Cordis), PTFE Covered Stents: Fluency® (Bard), Advanta V12® (Atrium) and Viatorr® (Gore), Transjugular intrahepatic portosystemic shunt (TIPS)
- Where
- 12 sites in France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Tours
Liver Cirrhoses
Early Use of TIPS With Polytetrafluoroethylene(PTFE) Covered Stents in Cirrhotic Patients With Refractory Ascites
This multicenter RCT is designed to investigate if TIPS with covered stents improves transplant-free survival for cirrhotic patients with early stage of refractory ascites compared to LVP+albumin during 1 year follow-up period.
- Trial name
- NCT03172273
- Testing
- TIPS, paracentesis
- Where
- 2 sites in China
- Volunteers
- 180 people
- Sponsor
- Air Force Military Medical University, China
Portal Hypertension, Portal Vein Thrombosis
Preemptive TIPS for Variceal Bleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis
Portal vein thrombosis (PVT) can lead to a further increase in portal venous pressure and increase the risk of rebleeding. Whether patients with acute esophagogastric variceal bleeding with occlusive PVT benefit from preemptive…
- Conditions
- Portal Hypertension, Portal Vein Thrombosis, Esophageal Varix Bleeding, Portosystemic Shunt
- Trial name
- NCT06122753
- Testing
- preemptive TIPS, standard second prophylaxis
- Where
- China
- Volunteers
- 120 people
- Sponsor
- West China Hospital
Portal Hypertension
Austrian Registry on Transjugular Intrahepatic Portosystemic Shunts
Patients with TIPS will be recruited in this prospective registry study. The clinical course will be documented and biomarkers for prediction of complicatiosn will be assessed.
- Trial name
- AUTIPS (NCT03409263)
- Testing
- Observational study
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Thomas Reiberger
Hepatic Encephalopathy, Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Coil-Assisted Small-Diameter Covered-Stent Shunt Reduction for Refractory Hepatic Encephalopathy After TIPS
Refractory hepatic encephalopathy (RHE) after transjugular intrahepatic portosystemic shunt (TIPS) is a serious complication that can markedly impair quality of life and worsen prognosis.
- Conditions
- Hepatic Encephalopathy, Transjugular Intrahepatic Portosystemic Shunt (TIPS), Portal Hypertension, Liver Cirrhosis
- Trial name
- NCT07799948
- Testing
- Coil-assisted Small-diameter Stent Shunt reduction
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Air Force Military Medical University, China
Portal Hypertension Related to Cirrhosis, Ascites Hepatic
Effectiveness and Safety of TIPS Stent Graft in the Treatment of Cirrhosis and Complications of Portal Hypertension
This Study is a prospective, multi-center, single-arm objective perform an criteria (OPC) study. A 12 months follow-up study on the patients who intend to receive the treatment of cirrhosis and complications of portal…
- Conditions
- Portal Hypertension Related to Cirrhosis, Ascites Hepatic, Variceal Bleeding
- Trial name
- NCT06669806
- Testing
- TIPS Stent Graft
- Where
- China
- Volunteers
- 166 people
- Sponsor
- C. R. Bard