Clinical trials: Positive Affect
HIV/AIDS
Positive Affect Promotion to Empower Optimal Adherence to HIV Therapy
This study assesses the feasibility and acceptability of the APPEAL program, a 3-session intervention designed to promote positive affect among men and women living with HIV infection.
- Trial name
- NCT04035759
- Testing
- APPEAL
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- State University of New York - Downstate Medical Center
Suicidal Ideation, Suicide, Attempted
Skills to Enhance Positive Affect in Suicidal Adolescents
The prevalence of suicidal behaviors in adolescents remains unacceptably high and is a significant public health concern. The investigators propose a new treatment approach in which skills to increase positive emotions are taught…
- Trial name
- STEP (NCT02130583)
- Testing
- Positive Affect Skills Training, Treatment as Usual
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Brown University
Depression
Mindfulness Training During Accelerated TMS for Depression
This NIH-funded single-arm pilot tests the feasibility, acceptability, and preliminary effects of embedding brief guided mindfulness practice (via the Waking Up smartphone app) into the inter-session intervals of clinically…
- Trial name
- NCT07369557
- Testing
- Guided Mindfulness Practice using a study created web app that links to the commercially available Waking Up app
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Vaccination; Infection
Mood and Influenza Vaccine Response: A Feasibility Trial
This study is a 2-arm, parallel, randomised controlled feasibility trial of a brief video intervention designed to induce positive affect (mood) in older adults in primary care settings prior to the receipt of influenza…
- Trial name
- NCT03144518
- Testing
- Positive Affect Intervention, Neutral Control Intervention, Northern Hemisphere Influenza Vaccine 2017/18 (Delivered as part of Standard Care)
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Anxiety Disorders, Depressive Disorder
Feasibility of a Group Blended Transdiagnostic CBT Protocol for Emotional Disorders
The aim of this study is to analyze the feasibility of a blended transdiagnostic group protocol for the treatment of depression and anxiety disorders (emotional disorders) in a one-group clinical trial.
- Trial name
- NCT04008576
- Testing
- Group Blended Transdiagnostic treatment
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universitat Jaume I
Alcoholism, Healthy
The Effect of Positive and Negative Emotions on Brain Activity in Alcoholics and Nonalcoholics
This study was designed to learn more about the areas of the brain involved in the experience of positive and negative emotions.
- Trial name
- NCT00001675
- Where
- United States
- Volunteers
- 1,194 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Depression, Psychological Stress
Online Positive Emotion Skills Intervention for Symptoms of Depression
Major depressive disorder affects over 120 million people worldwide. Only 50% of Americans with depression receive adequate treatment, and one-third of those receiving treatment do not benefit.
- Conditions
- Depression, Psychological Stress, Affect
- Trial name
- MARIGOLD (NCT02861755)
- Testing
- Positive Affect Skills Training, 5-week Emotion Reporting
- Where
- United States
- Volunteers
- 677 people
- Sponsor
- Northwestern University
Depression, Anxiety
Brightline: Advancing Mental Health on Campus
This observational study will employ a multi-modal observation methodology, integrating data from wearable devices and smartphones to establish comprehensive digital biomarkers for identifying symptoms of mental health conditions…
- Conditions
- Depression, Anxiety, Stress, Positive Affect
- Trial name
- NCT06770075
- Testing
- Observational
- Where
- Singapore
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
High Arousing Positive Emotion, Low Arousing Positive Condition
Do Different Arousal Levels Affect Pressure Pain Thresholds?
This study examines whether emotional arousal level alone, while maintaining positive emotional valence, can influence pressure pain thresholds (PPTs) in healthy adults.
- Trial name
- DDEALAPPT (NCT07802444)
- Testing
- Emotional high arousing intervention, Low arousal intervention
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Influenza Like Illness, Asthma
How Does the Clinical Tool 'What's Going Around' Affect Clinical Practice
Previous work has shown that the epidemiological context of a patient's presentation can provide important information for clinicians to aid in diagnosis and treatment.
- Conditions
- Influenza Like Illness, Asthma, Group A Streptococcal Infection, Pertussis
- Trial name
- WGA (NCT01979588)
- Testing
- What's Going Around tool, Control
- Where
- United States
- Volunteers
- 206,703 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
HIV/AIDS
Does Provision of Point of Care CD4 Technology and Early Knowledge of CD4 Levels Affect Early Initiation and Retention on Anti-retroviral Treatment (ART) in HIV Positive Pregnant Women in the Context of Option B+ for PMTCT?
The study will be conducted at 32 health care facilities in three provinces in Zimbabwe and will compare the impact of the provision Point of Care CD4 technology and early knowledge of CD4 levels on retention at 12 months, with…
- Trial name
- E4E (NCT02070900)
- Testing
- POC CD4, Programmatic Mentoring
- Where
- 32 sites in Zimbabwe
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- WHO, Department of Maternal, Newborn, Child and Adolescent Health
Healthy Volunteers
Effect of Interest-Based Physical Training on Exercise Adherence
This study aims to examine whether a physical training program designed based on individual interests can improve exercise adherence and physical fitness among college students, and to explore whether positive affective…
- Trial name
- NCT07635927
- Testing
- Interest-Based Physical Training；, Regular Physical Training
- Where
- China
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Capital University of Physical Education and Sports, China
Depression and Anxiety Symptoms
The Effect of Loving-Kindness Meditation on Mood and Anxiety Symptoms, Interpersonal Relationships, and Emotions: An Initial Randomized Controlled Trial With a Non-Clinical Sample of Undergraduate Women
The goal of this clinical trial was to examine the effects of Loving-Kindness Meditation (LKM) on anhedonic depressivity, interpersonal relationships (other inclusive self-concept, willingness to sacrifice, interaction quality)…
- Trial name
- NCT07611253
- Testing
- Loving-Kindness Meditation, Visualization
- Where
- Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Luis Flores
Trauma, Psychological, Personality Disorders
Strengthening the Healthy Adult Mode: a Case Experimental Study Exploring the Effects of a New Schema Therapy Protocol in an Adult Outpatient Population.
Background: Strengthening the Healthy Adult schema mode is the ultimate goal in Schema Therapy, working as an assumed mechanism of long-term change through improved positive mental health.
- Conditions
- Trauma, Psychological, Personality Disorders, Chronic Psychiatric Disorder
- Trial name
- ST-HA (NCT04466163)
- Testing
- Schema Therapy and the Healthy Adult
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Zuyderland Medisch Centrum
Autism Spectrum Disorder
Social ABCs for Toddlers With Signs of Autism Spectrum Disorder: Trial of a Parent-Mediated Intervention
The Social ABCs is an innovative parent-mediated intervention for toddlers with confirmed or suspected Autism Spectrum Disorder (ASD).
- Trial name
- NCT02428452
- Testing
- Social ABCs parent-mediated intervention program
- Where
- 2 sites in Canada
- Volunteers
- 63 people
- Sponsor
- Jessica Brian
Aging, Chronic Low-back Pain
Adaptability and Resilience in Aging Adults-2
Chronic low back pain is a major health concern among older adults and is associated with increased economic, functional, and psychological burden.
- Trial name
- ARIAA-2 (NCT04068922)
- Testing
- Resilience Intervention
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Florida
Affect, Wellness, Psychological
The Effects of Walking in Nature (vs. an Urban Setting) on the Wellbeing of Postsecondary Students.
The goal of this randomized controlled trial is to examine the effects of a walking intervention (3 walks per week for a period of 4 weeks) in a nature vs. urban setting on the wellbeing of young adult postsecondary students.
- Conditions
- Affect, Wellness, Psychological, Depressive Symptoms, Anxiety Disorders and Symptoms
- Trial name
- NCT05889078
- Testing
- A 4-week walking intervention
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- McGill University
HIV/AIDS, HPV Infection
ORCHID: An Online Intervention for Persons With HIV (Miami)
The purpose of this research is to test ORCHID (Optimizing Resilience \& Coping with HIV through Internet Delivery), a skills-building intervention that improves mental health status for persons with HIV, who are at-risk for…
- Trial name
- ORCHID-Miami (NCT05935644)
- Testing
- ORCHID
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Cancer
Emotion Regulation and Pain in Children With Cancer
This study tested the effects of emotion regulation strategies (reappraisal, reassurance, and empathy) on pain responses in children with cancer.
- Trial name
- NCT03133507
- Testing
- Reapprasial Condition, Reassurance Condition, Distraction Condition
- Volunteers
- 73 people
- Sponsor
- University of California, Irvine
Anxiety Disorders, Public Speaking Fear
Reward Processes and Rehearsal in Exposure Therapy
The purpose of this study is to 1) examine the importance of self-reported relief following exposure and 2) test whether positive-focused rehearsal following exposure can improve treatment outcomes for participants who endorse…
- Trial name
- NCT06132425
- Testing
- Exposure, Rehearsal
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of California, Los Angeles