Clinical trials: Positive Attitude
Internet-based Treatment for Depression
Internet Delivered Intervention Program for the Prevention and Treatment of Depression
The purpose of this study is to determine the differential effectiveness of a self applied treatment delivered via Internet for the prevention and treatment of depression, with or without support by the therapist, compared to a…
- Trial name
- NCT02148354
- Testing
- Smiling is Fun
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universitat Jaume I
Osteoarthritis, Knee, Psychological Stress
Positive Cueing in Knee Arthroplasty.
To the knowledge of the investigators, the feasibility of an RCT assessing the use of positive cueing in an information video for patients undergoing primary TKA is currently unclear.
- Conditions
- Osteoarthritis, Knee, Psychological Stress, Mental Stress
- Trial name
- NCT05703087
- Testing
- Positive cueing in the information video before a primary TKA
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Leiden University Medical Center
Mental Health Wellness 1
Be a Mom: Effectiveness of an eHealth Intervention for Promoting Maternal Mental Health
Be a mom (a web-based cognitive-behavioral intervention) is being tested in another trial as a preventive intervention in the postpartum period (NCT03024645).
- Trial name
- BeAMom (NCT04055974)
- Testing
- Be a Mom
- Where
- Portugal
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Sleep Apnea Syndromes
Effect of Self-Management on Improving Sleep Apnea Outcomes
Obstructive sleep apnea syndrome (OSA) is a common sleep disorder that is associated with serious medical and psychological complications.
- Trial name
- NCT00310310
- Testing
- Sleep Apnea Self-Management Program, Usual care
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Smoking, HIV Infections
Smoking Cessation Using Motivational Therapy and Varenicline
People that are infected with HIV appear to be especially susceptible to the adverse effects of cigarette smoking. The purpose of this study is to determine if quitting smoking by using a specialized smoking cessation treatment…
- Trial name
- NCT00701896
- Testing
- Varenicline tartrate, Nicotine Replacement Therapy, Biological Control
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Philip Diaz
Advanced Cancer, Demoralization
A Feasibility Study of a Digitally-enabled Psychological Intervention for Demoralization in Advanced Cancer Patients
Advanced cancer is a leading cause of death worldwide and in China. Cancer patients often face reduced independence and self-care abilities, which may lead to psychological disturbances such as helplessness, hopelessness, or…
- Conditions
- Advanced Cancer, Demoralization, Psychological Intervention
- Trial name
- NCT07872254
- Testing
- A digitally-enabled positive psychological intervention for demoralization in advanced cancer patients
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Positive Parenting, Child Maltreatment
Parenting in the Preschool System in Malaysia
This study aims to evaluate the effectiveness of a hybrid human-digital playful parenting programme, "Naungan Kasih-Hybrid (NK-Hybrid)", in Malaysia.
- Conditions
- Positive Parenting, Child Maltreatment, Child Development, Child Behavior
- Trial name
- NCT07599566
- Testing
- Naungan Kasih Positive Parenting Programme
- Where
- Malaysia
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Major Depressive Disorder, Low Mood
Positive Feedback vs. No-Feedback Games for Behavioral Change
We aim to investigate here whether we can develop a reinforcement learning game which provides game-based feedback to encourage positive actions (behaviors) both inside and outside of the game.
- Trial name
- NCT06025838
- Testing
- positive feedback
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Bard College
Quality of Life, Physical Exercise
Physical Activity and Motivation in Colorectal Cancer Patients
The intervention will be a physical exercise program for colorectal cancer patients during the adjuvant chemotherapy. The exercise program aims on reducing the side effects of the treatment and improving patients' quality of…
- Conditions
- Quality of Life, Physical Exercise, Motivation, Side Effect
- Trial name
- NCT04506840
- Testing
- Physical activity
- Where
- 2 sites in Spain
- Volunteers
- 32 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Depression
B Vitamins in MTHFR Positive Patients With Major Depression: A Post Hoc Analysis of Findings
A randomized double-blind placebo controlled study of reduced B vitamins in patients with major depression who were positive for one or both of the common MTHFR polymorphisms was conducted between 8/1/2014 and 4/3/2015.
- Trial name
- BVMD (NCT02709668)
- Testing
- Enlyte
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- High Point Regional Health Systems
Myocardial Infarction, Acute
Gratitude Intervention in Promoting Self-care in Patients With Myocardial Infarction
Introduction: Positive psychological's constructs have shown a direct effect on adherence to pharmacological treatment, diet, physical activity and general commitment to health, in the same way that negative ones, such as…
- Trial name
- GReATCARE (NCT05955950)
- Testing
- Gratitude list, List of any event
- Where
- Brazil
- Volunteers
- 132 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
HIV Medication Adherence, Methamphetamine Use
Intervention Targeting Medication Adherence and Methamphetamine Use in HIV Positive Men (ACE)
The primary aim is to test an innovative 8-session intervention, based on Motivational Interviewing and Cognitive Behavioral Skills-Training for the co-occurrence of methamphetamine use and highly active antiretroviral therapy…
- Conditions
- HIV Medication Adherence, Methamphetamine Use, Sexual Risk, Poly-substance Use
- Trial name
- ACE (NCT01122186)
- Testing
- Motivational Interviewing + Cognitive Behavioral Skills Training, Education Attention Control
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Hunter College of City University of New York
Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8
Exercise Intervention After Cancer Treatment for Improving Health in Stage II-III Breast Cancer Survivors
This pilot trial studies how well exercise intervention after cancer treatment works in improving physical activity in stage II-III breast cancer survivors. An exercise intervention may promote regular physical activity.
- Conditions
- Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- PACT (NCT03523195)
- Testing
- Exercise Intervention, Informational Intervention, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Fred Hutchinson Cancer Center
Caregiver Burden, Mental Health Issue
Effectiveness of Positive Psychotherapy on Mental Wellbeing Among Caregivers of Cerebral Palsy Children
The Central idea of the proposed research proposal is first to translate adapt and validate the Caregiver Difficulties Scale \& Positive Psychotherapy sessions based manual into Urdu language then secondly, assessment of burnout…
- Conditions
- Caregiver Burden, Mental Health Issue, Cerebral Palsy
- Trial name
- NCT05613595
- Testing
- Positive Psychotherapy, Counseling Group
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- International Islamic University, Islamabad
Tuberculosis, HIV
Alcohol Reduction Among People With TB and HIV in India
The highest incidence of tuberculosis disease (TB) in the world is in India, accounting for 27% of all new cases globally, with approximately 86,000 among persons with HIV (PWH).
- Trial name
- HATHI (NCT04230395)
- Testing
- HATHI Intervention, Usual Care
- Where
- 2 sites in India
- Volunteers
- 450 people
- Sponsor
- Johns Hopkins University
Alcohol Use Disorder, Anxiety
Amplification of Positivity for Alcohol Use
The proposed study consists of two phases. During Phase 1, the investigators will recruit a small sample of participants to complete a psychosocial intervention termed Amplification of Positivity (AMP) for individuals…
- Conditions
- Alcohol Use Disorder, Anxiety, Depression
- Trial name
- AMP-A (NCT06030154)
- Testing
- Cognitive Behavioral Therapy, Amplification of Positivity Therapy, Surveys and Interviews
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Depression, HIV Infections
PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects
Background: Human immunodeficiency virus (HIV) infection is a serious disease with no cure. Some people with HIV have depression and other mood problems. They can have problems with thinking and memory.
- Conditions
- Depression, HIV Infections, HIV-Associated Cognitive Motor Complex
- Trial name
- NCT03581305
- Testing
- 18F-FDOPA, 11C-DASB
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Oncologic Complications
Patient Intake At the 'MOvement and REhabilitation (MO.RE.)
In recent years, there has been an exponential increase in studies regarding the benefits of physical activity in oncology, with significant results on improving both physical and psychological outcomes.
- Trial name
- BACKMORE2024 (NCT06858241)
- Where
- Italy
- Volunteers
- 95 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Smoking Cessation, Smoking, Tobacco
Version 2 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS)
The overall goal of this pilot study is to solicit feedback from nondaily smokers looking for smoking cessation support online (n=90) about Version 2 of a smartphone app investigators designed to support smoking cessation, and to…
- Trial name
- NCT03951766
- Testing
- Smiling Instead of Smoking (SiS) App Version 2
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Effects of Different Meals on the QT/QTc Interval, Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use
Food and Insulin Effect on QT/QTC Interval of ECG
Moxifloxacin is routinely used as a probe to confirm assay sensitivity in thorough electrocardiogram (ECG) studies. It has been shown that a meal shortens the QT interval, which may affect pharmacokinetics (PK) and/or…
- Conditions
- Effects of Different Meals on the QT/QTc Interval, Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use, C-Peptide Effects on the QT/QTc Interval, Moxifloxacin ECG Profile in Fed and Fasted State
- Trial name
- C11035 (NCT01642485)
- Testing
- Moxifloxacin 400 mg fasted, FDA breakfast, Continental breakfast
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Richmond Pharmacology Limited