Clinical trials: Positive End Expiratory Pressure (PEEP)
Morbid Obesity
Effect of Positive End Expiratory Pressure at the Time of Induction in Morbidly Obese Patients
Background: Positive end expiratory pressure (PEEP) at the time of induction increases oxygenation by preventing lung atelectasis. However, PEEP may not prove beneficial in all cases.
- Trial name
- NCT03024658
- Testing
- positive end expiratory pressure (PEEP)
- Volunteers
- 70 people
- Sponsor
- Sri Aurobindo Institute of Medical Sciences
Cardiac Arrest (CA), Out-of-hospital Cardiac Arrest (OHCA)
The Application of Positive End-Expiratory Pressure in Out-of-Hospital Cardiac Arrest: The Lazarus-PEEP Trial.
The goal of this clinical trial is to learn whether using Positive End-Expiratory Pressure (PEEP) during cardiopulmonary resuscitation (CPR) improves outcomes for adults who experience out-of-hospital cardiac arrest, a condition…
- Conditions
- Cardiac Arrest (CA), Out-of-hospital Cardiac Arrest (OHCA), Positive End-expiratory Pressure (PEEP), Ventilation During Resuscitation
- Trial name
- Lazarus-PEEP (NCT06939335)
- Testing
- Disposable PEEP Valve set at 5 cm H20., Controle
- Where
- 7 sites in Belgium, France
- Volunteers
- 132 people
- Sponsor
- University Hospital, Ghent
Respiratory Failure
NAVA Versus BiPAP Non-Invasive Respiratory Support in Infants Following Congenital Heart Surgery
Pediatric patients often require prolonged mechanical ventilation after cardiac surgery which comes with many undesirable effects.
- Trial name
- NAVA (NCT03180385)
- Testing
- Neurally-Adusted Ventilatory Assist (NAVA), Biphasic Positive Airway Pressure Support (BiPAP)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Surgery
Haemodynamic and Respiratory Effects of a Low Positive End Expiratory Pressure Associated With a Fluid Challenge in Knee-chest Position
The genu pectoral position is a surgical position used for spine surgery. This surgical position will lead to physiological hemodynamic and respiratory changes during the procedure.
- Trial name
- OPTIPEP (NCT06378710)
- Testing
- Optimized PEEP
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Caen
Regional Cerebral Oxygen Saturation
Effect of Different Positive End Expiratory Pressures on Regional Cerebral Oxygen Saturation
The goal of this prospective single-blind randomized clinical trial is to compare the effect of two different positive end expiratory pressure (PEEP) levels on regional cerebral oxygen saturation in patients scheduled for…
- Trial name
- NCT05961917
- Testing
- 5 cmH2O Positive end-expiratory pressure (PEEP), 10 cmH2O Positive end-expiratory pressure (PEEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bozyaka Training and Research Hospital