Clinical trials: Post - Tonsillectomy Pain
Post Tonsillectomy Pain
A Comparative Study With Parenteral Oxycodone, Morphine and Dexamethasone in Postoperative Pain in Paediatric Patients
The aim of this randomized, double-blind study is to compare parenteral pre-emptive oxycodone, morphine and dexamethasone with placebo in the treatment of postoperative pain in paediatric patients 4 to 12 years of age.
- Trial name
- DOM (NCT00733083)
- Testing
- 0,1 mg/kg of oxycodone, Morphine 0,1 mg/kg, Dexamethasone 0,5 mg/kg
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Turku
Dehydration
Measuring Pain and Hydration After Tonsillectomy
Pain after tonsillectomy remains a key barrier during the post operative period. The published return rate to the emergency department for hydration and pain control is approximately 4%.
- Trial name
- NCT02011230
- Testing
- Hoist Group
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Post Operative Pain
The Effectiveness of Local Infiltration Technique in Adult Tonsillectomy
Tonsillectomy is commonly associated with postoperative pain. The modified pre-incision infiltration of anesthetic mixture combined with general anesthesia was shown to decrease post-tonsillectomy pain in children.
- Trial name
- NCT03806335
- Testing
- Infiltration, General anesthesia
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Post-operative Pain
How Does Gabapentin Affects Post-operative Tonsillectomy Pain?
Gabapentin is a medicine that has been used in adults (but not yet in children) to treat pain after surgery. In children it has been used for many years to treat other conditions and has been shown to be very safe.
- Trial name
- NCT00624455
- Testing
- Gabapentin
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain, Postoperative
Bupivacaine in Tonsillectomy
A placebo-controlled and double-blind study is planned according to current legislation and ICH GCP guidelines with 80 patients at Nordland Hospital, Bodø.
- Trial name
- NCT04825704
- Testing
- Bupivacaine, Sodium chloride
- Where
- Norway
- Volunteers
- 84 people
- Sponsor
- Nordlandssykehuset HF
IPRF Post Tonsillectomy
Injectable Platelet Rich Fibrin Post Tonsillectomy
To evaluate the effect of injectable Prf on healing, hemostasis and pain post tonsillectomy
- Trial name
- NCT06304935
- Testing
- Use of injectable platelet rich fibrin after tonsillectomy by injection of IPRF in one tonsillar bed and use of other side as control
- Volunteers
- 100 people
- Sponsor
- Assiut University
Post Operative Pain
Peri Tonsillar Infiltration of Ketamine or Bupivacaine for Post Tonsillectomy Analgesia
Comparison between the analgesic effect of local infiltration of either Bupivacaine or ketamine in the peritonsillar area before the incision of tonsillectomy to achieve postoperative analgesia
- Trial name
- NCT05341323
- Testing
- Ketamine., Bupivacaine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
Postoperative Pain, Postoperative Nausea and Vomiting
Effect of Steroids on Post-tonsillectomy Morbidities
This study aims to evaluate the effect of postoperative systemic rapid onset and short acting dexamethasone followed by a tapering dose of oral prednisolone on post-tonsillectomy morbidities.
- Trial name
- NCT02401529
- Testing
- IV dexamethasone, Oral prednisolone, Paracetamol
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Fahd General Hospital
Post Operative Pain, Postoperative Hemorrhage
Efficacy of Local Infiltration of Tranexamic Acid and Lidocaine in Tonsillar Bed on Postoperative Bleeding and Pain During Tonsillectomy Surgery: Prospective, Randomized, Control Study
All anesthetic techniques aim to lessen intra-operative surgical site bleeding because it is a major problem and does not help with precision, surgery time, or postoperative wound healing.
- Trial name
- NCT05817474
- Testing
- lidocaine (2 %) 2 ml and tranexamic acid
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- mohamed
Tonsillectomy
Celecoxib After Tonsillectomy
Tonsillectomy is one of the most common pediatric surgical procedures in the United States. Postoperative pain is substantial, with typical regimens employing narcotic derivatives and acetaminophen for 1-2 weeks after surgery.
- Trial name
- NCT02934191
- Testing
- Celecoxib, Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Children's Hospital of Philadelphia
Post-tonsillectomy Pain, Post-tonsillectomy Activity
The Effects of Reducing Stomach Acid on Post-tonsillectomy Pain
This study was designed to determine whether post-operative pain following a tonsillectomy can be reduced by adding an antacid-like medication to the medications taken after surgery.
- Conditions
- Post-tonsillectomy Pain, Post-tonsillectomy Activity, Post-tonsillectomy Hydration
- Trial name
- NCT00472186
- Testing
- Lansoprazole
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Post Tonsillectomy Pain
The Effect of Pre Surgery Dog Visits on Post Surgery Consumption of Pain Medication
The objective of this study is to examine the effects of pre surgery dog visits as compared to a costumed character or parents-only on the consumption of pain medication after surgery.
- Trial name
- Dog (NCT00452738)
- Testing
- Therapy dog, Costumed character, Parents-only
- Where
- United States
- Sponsor
- Oklahoma State University Center for Health Sciences
Adenotonsillectomy, Post-operative Analgesia
Non-opioids for Analgesia After Adenotonsillectomy in Children
The goal of this study is to determine if non-opioid pain control is a safe way to manage pain after adenotonsillectomy surgery in children.
- Conditions
- Adenotonsillectomy, Post-operative Analgesia, Opioid Use
- Trial name
- NCT03618823
- Testing
- Oxycodone, Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- David Chi, MD
Pain, Postoperative, Tonsillar Hypertrophy
Management of Post-Tonsillectomy Pain in Pediatric Patients
Single-center, randomized, open-label, non-inferiority treatment pilot study to evaluate the effectiveness of a combined acetaminophen and ibuprofen regimen for treatment of post-operative tonsillectomy pain in the pediatric…
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis
- Trial name
- NCT04551196
- Testing
- Alternating Acetaminophen and Ibuprofen, Combined Acetaminophen and Ibuprofen
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Obstructive Sleep Apnea, Tonsillitis
Pediatric Pain Optimization After Tonsillectomy
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery.
- Conditions
- Obstructive Sleep Apnea, Tonsillitis, Pain, Procedural
- Trial name
- NCT05244226
- Testing
- Fentanyl/Hydromorphone, Methadone
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Duke University
Postoperative Pain
Tramadol Infiltration for Tonsillectomy
The purpose of this study is to evaluate the analgesic effect and IL-6 after tramadol infiltration or intravenous for tonsillectomy.
- Trial name
- NCT01636700
- Testing
- Tramadol 2mg/kg, Saline solution
- Where
- Brazil
- Sponsor
- Federal University of São Paulo
Pain
Does Montelukast Decrease Post Adenotonsillectomy Pain in Children
Objective: The purpose of the present study is to evaluate the effectiveness of preoperative Montelukast as an analgesic for adenotonsillectomy Study Design: Randomized controlled double blinded clinical trial.
- Trial name
- Montelukast (NCT02793375)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pain
Efficacy of a Nurse Telephone Follow-up on Pain Intensity After Removal of Tonsils in Children
The purpose of this study is to determine if a nurse telephone follow-up to parents of children who underwent a removal of their tonsils would be effective in reducing pain intensity, complications and resort to other healthcare…
- Trial name
- NCT01568372
- Testing
- Telephone follow-up
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Pain, Postoperative, Postoperative Hemorrhage
Effect of Bupivacaine-infused Fibrin Sealant Application on Post-tonsillectomy Pain & Hemorrhage
The purpose of this study is to evaluate the effect of combining two interventions already in use at some institutions for reducing post-operative pain following tonsillectomy or adenotonsillectomy.
- Trial name
- NCT02343263
- Testing
- Bupivacaine, Fibrin Sealant
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pain, Acute
Comparative Study Between the Effect of Diclofanic and Ketorolac in Post Tonsillectomy Pain Management
Compare between the analgesic efficacy of diclofenac sodium and ketorolac tromethamine in post-tonsillectomy pain management.and Compare between the effect of diclofenac sodium and ketorolac tromethamine on post-tonsillectomy…
- Trial name
- NCT03178539
- Testing
- diclofenac, ketorolac
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University